The triple co-expression of casScer\UAS.cKa, grhScer\UAS.cBa and AntpScer\UAS.cMb triggers an apparent reduction in the numbers of dividing neuroblasts and dividing neuroblast daughters in stage 12 embryos, as compared to controls.
Co-expression of casScer\UAS.cKa and AntpScer\UAS.cMb under the control of Scer\GAL4GMR42G10 results in a significant reduction in thoracic neuroblast proliferation at stage 12 (but not 14), neuroblast daughter cell proliferation at stage 14 (but not stage 12), and abdominal neuroblast and neuroblast daughter cell proliferation at both stage 12 and 14, as compared with controls.
Co-expression of E(spl)m8-HLHCK2.Scer\UAS.T:Zzzz\FLAG, casScer\UAS.cKa and AntpScer\UAS.cMb under the control of Scer\GAL4GMR42G10 enhances the reduced proliferation phenotype in neuroblast daughter cells, but does not enhance the reduced proliferation of neuroblasts, as compared with embryos expressing casScer\UAS.cKa and AntpScer\UAS.cMb under the control of Scer\GAL4GMR42G10.
Addition of AntpScer\UAS.cMb to Dfd16;Scr4 double mutant embryos (under the control of Scer\GAL4salm-459.2) results in both the Mx and Lb segments forming tracheal tubes instead of migratory gland primordia.
Expression of AntpScer\UAS.cMb under the control of Scer\GAL4lab.PH rescues the tritocerebral defects seen in lab14 embryonic brains. 34.9% of embryos show a complete rescue of the defects (taking into account that the phenotypic penetrance of the lab14 phenotype is 88.6%).
Co-expression of hthScer\UAS.cPa partially suppresses the antenna to leg transformation phenotypes produced by ectopic expression of AntpScer\UAS.cMb driven by Scer\GAL4dpp.blk1. The antennae produced are aristaless and occasionally duplicated, similar to the hthScer\UAS.cPa phenotype.