FlyBase Allele Report: Dmel\Myt1[GMR.PP]

General Information

Symbol

Dmel\Myt1^GMR.PP

Species

D. melanogaster

Name

glass multimer reporter construct of Price

FlyBase ID

FBal0138466

Feature type

allele

Associated gene

Dmel\Myt1

Associated Insertion(s)

Carried in Construct

P{GMR-Myt1.P}

Key Links

Transgenic product class

cDNA

(Price et al., 2002)

wild_type

(Price et al., 2002)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Price et al., 2002)

wild_type

(Price et al., 2002)

Mutagen

in vitro construct

(Price et al., 2002)

Progenitor genotype

Carried in construct

P{GMR-Myt1.P}

Cytology

Description

GMR regulatory sequences drive expression of a Myt1 cDNA fragment.

(Price et al., 2002)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

Myt1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Price et al., 2002)

Phenotype Manifest In

eye disc

(Price et al., 2002)

eye photoreceptor cell

(Price et al., 2002)

eye photoreceptor cell | increased number

(Price et al., 2002)

ommatidial precursor cluster

(Price et al., 2002)

ommatidium

(Price et al., 2002)

rhabdomere

(Price et al., 2002)

secondary pigment cell

(Price et al., 2002)

tertiary pigment cell

(Price et al., 2002)

Detailed Description

Statement

Reference

Flies expressing Myt1^GMR.PP have a dose sensitive rough eye phenotype. Mitoses in the second mitotic wave are reduced in number and delayed compared to wild type in third larval instar eye discs. Mitoses ahead of the morphogenetic furrow are unaffected. Ommatidial preclusters in the adult eye appear disorganised. Most ommatidial cell types appear to be present, but the number of photoreceptor cells in each ommatidium is often abnormal, with ommatidia containing too few or too many photoreceptor cells. The regular array of secondary and tertiary pigment cells is severely disrupted and the arrangement and size of the rhabdomeres is often irregular.

(Price et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Myt1^GMR.PP has visible phenotype, enhanceable by Df(2L)Mdh

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by Df(3R)Delta-BX12

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by Df(3R)Dr-rv1

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by Delta³

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by Delta⁷

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by Delta^B2

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by Df(2L)net-PMF

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by Delta^RevF10

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by stg^unspecified/stg[+]

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by Df(2L)r10

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by Cdk1^unspecified/cdc2[+]

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by Df(3L)pbl-X1

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, enhanceable by Df(3R)3450

(Price et al., 2002)

NOT Enhanced by

Statement

Reference

Myt1^GMR.PP has visible phenotype, non-enhanceable by CycA^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-enhanceable by CycB^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-enhanceable by CycE^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-enhanceable by dap^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-enhanceable by fzy^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-enhanceable by grp^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-enhanceable by mei-41^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-enhanceable by twe^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-enhanceable by Cdk2^unspecified

(Price et al., 2002)

Suppressed by

Statement

Reference

Myt1^GMR.PP, Wee1^GMR.PP has visible phenotype, suppressible by trbl^unspecified/trbl[+]

(Price et al., 2002)

Myt1^GMR.PP, Wee1^GMR.PP has visible phenotype, suppressible by N^unspecified

(Price et al., 2002)

NOT suppressed by

Statement

Reference

Myt1^GMR.PP has visible phenotype, non-suppressible by CycA^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-suppressible by CycB^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-suppressible by CycE^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-suppressible by Cdk2^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-suppressible by dap^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-suppressible by fzy^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-suppressible by grp^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-suppressible by mei-41^unspecified

(Price et al., 2002)

Myt1^GMR.PP has visible phenotype, non-suppressible by twe^unspecified

(Price et al., 2002)

Suppressor of

Statement

Reference

Myt1^GMR.PP is a suppressor of visible phenotype of p53^GMR.Ex

(Price et al., 2002)

Other

Statement

Reference

Myt1^GMR.PP, Wee1^GMR.PP has visible phenotype

(Price et al., 2002)

Phenotype Manifest In

Enhanced by

Statement

Reference

Myt1^GMR.PP has eye phenotype, enhanceable by Df(2L)Mdh

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by Df(3R)Delta-BX12

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by Df(3R)Dr-rv1

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by Delta³

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by Delta⁷

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by Delta^B2

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by Delta^RevF10

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by Df(2L)net-PMF

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by stg^unspecified/stg[+]

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by Cdk1^unspecified/cdc2[+]

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by Df(2L)r10

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by Df(3L)pbl-X1

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, enhanceable by Df(3R)3450

(Price et al., 2002)

NOT Enhanced by

Statement

Reference

Myt1^GMR.PP has eye phenotype, non-enhanceable by CycA^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-enhanceable by CycB^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-enhanceable by CycE^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-enhanceable by dap^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-enhanceable by fzy^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-enhanceable by grp^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-enhanceable by mei-41^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-enhanceable by twe^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-enhanceable by Cdk2^unspecified

(Price et al., 2002)

Suppressed by

Statement

Reference

Myt1^GMR.PP, Wee1^GMR.PP has eye phenotype, suppressible by trbl^unspecified/trbl[+]

(Price et al., 2002)

Myt1^GMR.PP, Wee1^GMR.PP has eye phenotype, suppressible by N^unspecified

(Price et al., 2002)

NOT suppressed by

Statement

Reference

Myt1^GMR.PP has eye phenotype, non-suppressible by CycB^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-suppressible by CycE^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-suppressible by Cdk2^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-suppressible by dap^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-suppressible by fzy^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-suppressible by grp^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-suppressible by mei-41^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-suppressible by twe^unspecified

(Price et al., 2002)

Myt1^GMR.PP has eye phenotype, non-suppressible by CycA^unspecified

(Price et al., 2002)

Suppressor of

Statement

Reference

Myt1^GMR.PP is a suppressor of eye phenotype of p53^GMR.Ex

(Price et al., 2002)

Myt1^GMR.PP is a suppressor of interommatidial bristle phenotype of p53^GMR.Ex

(Price et al., 2002)

Other

Statement

Reference

Myt1^GMR.PP, Wee1^GMR.PP has eye phenotype

(Price et al., 2002)

Myt1^GMR.PP, stg^unspecified/stg[+] has interommatidial bristle phenotype

(Price et al., 2002)

Myt1^GMR.PP, stg^unspecified has interommatidial bristle phenotype

(Price et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Myt1^GMR.PP stg^unspecified/+ eyes lack bristles. The eye phenotype caused by two copies of Myt1^GMR.PP combined with a single copy of wee^GMR.PP is partially suppressed by removal of one copy of trbl. The eye phenotype caused by two copies of Myt1^GMR.PP combined with a single copy of wee^GMR.PP is enhanced by Dl^unspecified, Df(2L)net-PMF, Df(2L)Mdh, Df(2L)r10, Df(2R)vg-C, Df(3R)Dl-BX12, Df(3R)3450 or Df(3R)Dr-rv1. The eye phenotype caused by two copies of Myt1^GMR.PP combined with a single copy of wee^GMR.PP is suppressed by N^unspecified, Df(1)N-8 or Df(3L)st4.

(Price et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Myt1^GMR.PP

Name Synonyms

glass multimer reporter construct of Price

(Price et al., 2002)

Secondary FlyBase IDs

References (1)

Report Sections

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