FlyBase Allele Report: Scer\GAL4[NP0225]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Scer\GAL4^NP0225

General Information

Symbol

Scer\GAL4^NP0225

Species

S. cerevisiae

Name

FlyBase ID

FBal0181651

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Also Known As

NP225-GAL4, NP225, GAL4-NP225, NP225Gal4

Genomic Maps

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

Cytology

Description

Allele components

Component

Use(s)

Inserted element

Encoded product / tool

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:14,479,031..14,479,031 [-]

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult antennal lobe projection neuron | subset

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus A1

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus A2

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus A3

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus A4

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus D4

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus D1

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus D5

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus I2

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus I4

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus L1

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus L2

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus L6

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus L8

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus M2

(Masuda-Nakagawa et al., 2005)

larval MB calyx glomerulus V5

(Masuda-Nakagawa et al., 2005)

adult antennal lobe projection neuron | subset

(Potter and Luo, 2010, Tanaka et al., 2004)

adult antennal lobe projection neuron

(Tanaka et al., 2008)

calyx of adult mushroom body

(Tanaka et al., 2008)

adult medial antennal lobe tract

(Tanaka et al., 2008)

adult lateral horn | restricted

(Potter and Luo, 2010)

adult antennal lobe glomerulus | subset

(Tanaka et al., 2004)

unilateral antennal lobe projection neuron | subset

(Tanaka et al., 2012)

adult antennal lobe projection neuron D adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DA2 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DL1 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DL4 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DL5 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM1 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM2 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM3 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM4 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM5 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DM6 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA2 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA3 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA4 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA6 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM2 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM3 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA7l adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VC1 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VC2 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM7v adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DA1 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DA3 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DA4l adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DC3 adPN

(Israel et al., 2022, Tanaka et al., 2012)

adult antennal lobe projection neuron DL3 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA1d adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA1v adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DC2 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VA7m lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VL2a adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VL2p lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM1 lPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron VM4 adPN

(Tanaka et al., 2012)

adult antennal lobe projection neuron DP1m adPN

(Tanaka et al., 2012)

adult uniglomerular antennal lobe projection neuron | subset

(Tanaka et al., 2012)

medial antennal lobe tract projection neuron

(Flybrain Neuron Database et al., 2018.6.28)

mushroom body pedunculus-vertical lobe arborizing neuron 1

(Flybrain Neuron Database et al., 2018.6.28)

uniglomerular antennal lobe projection neuron | subset

(Israel et al., 2022)

adult neuron | subset of adult subesophageal zone

(Israel et al., 2022)

adult neuron | subset of adult ventral nerve cord

(Israel et al., 2022)

Additional Information

Statement

Reference

Drives expression in a subset of larval mushroom body calyx glomeruli and of uniglomerular antennal lobe projection neurons.

(FlyBase Curators, 2017)

ScerGAL4^NP0225 drives expression in around 68 uniglomerular antennal lobe projection neurons. The cell bodies of around 31 of these neurons are positioned in the anterior-dorsal part of the antennal lobe. Around 29 cell bodies are found in the lateral part and around 9 are positioned ventrally. These neurons project to a large number of antennal lobe glomeruli including VM7d and VP4.

(Tanaka et al., 2012)

Expression is observed in 67-73 projection neurons in 35 of 43 antennal glomeruli.

(Tanaka et al., 2004)

Marker for

adult antennal lobe projection neuron

(Tanaka et al., 2008)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior | male, with VGlut1^UAS.cDa

(Grosjean et al., 2008)

abnormal learning | adult stage, with PQBP1^NIG.11820R

(Tamura et al., 2010)

abnormal locomotor behavior | adult stage | conditional, with Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.20xUAS.Venus}

(Aso et al., 2014)

abnormal memory | adult stage, with Ace^KK101926

(Gai et al., 2016)

Phenotype Manifest In

Detailed Description

Statement

Reference

Optogenetic activation (using Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.20xUAS.Venus} with 617 nm (red) light) of Scer\GAL4^NP0225 cells in adult females significantly increases angular speed, but not walking speed, compared to baseline, whereas no increase is seen in controls.

(Aso et al., 2014)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to rescue

Pde4^UAS.cCa/Scer\GAL4^NP0225 fails to rescue Pde4^dnc-1

(Scheunemann et al., 2012)

Syn^1-12.UAS/Scer\GAL4^NP0225 fails to rescue Syn⁹⁷

(Michels et al., 2011)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

605134

w¹¹¹⁸ P{10XUAS-IVS-Syn21-Chrimson-tdT-3.1}attP18; P{GawB}NP0225/CyO

112095

w^*; P{GawB}NP0225 / CyO, P{UAS-lacZ.UW14}UW14

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^NP0225

Scer\GAL4^NP225

Name Synonyms

Secondary FlyBase IDs

References (35)

Report Sections