FlyBase Allele Report: Scer\GAL4[Gyc89Db.3.4]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Scer\GAL4^Gyc89Db.3.4

General Information

Symbol

Scer\GAL4^Gyc89Db.3.4

Species

S. cerevisiae

Name

FlyBase ID

FBal0247197

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{Gyc89Db-GAL4.3.4}

Also Known As

Gyc-89Db^GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Morton et al., 2008)

Progenitor genotype

Carried in construct

P{Gyc89Db-GAL4.3.4}

Cytology

Description

A 3398bp fragment from the Gyc89Db promoter region is fused upstream of sequence encoding a GAL4 driver.

(Morton et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

Encoded product / tool

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

gustatory receptor neuron | subset

(Vermehren-Schmaedick et al., 2011)

gustatory receptor neuron | subset of labellum

Comment: 17 to 21 neurons

(Vermehren-Schmaedick et al., 2011)

Additional Information

Statement

Reference

ScerGAL4^Gyc-89Db.3.4 is expressed in a subset of the gustatory receptor neurons that innervate the labellar sensilla in third instar larvae. In the adult, it is expressed in a subset of the gustatory neurons of the labellum. Some of these gustatory neurons co-express the bitter-sensitive neuron marker DiscRFP^Gr66a.PD.

(Vermehren-Schmaedick et al., 2011)

Marker for

Reflects expression of

(Vermehren-Schmaedick et al., 2011)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal stress response | third instar larval stage, with Btau\PDE5A^UAS.cBa

(Vermehren-Schmaedick et al., 2010)

abnormal stress response | third instar larval stage, with CngA^KK108314

(Vermehren-Schmaedick et al., 2010)

abnormal stress response | third instar larval stage, with Gyc88E^GD11230

(Vermehren-Schmaedick et al., 2010)

abnormal taste perception, with Btau\PDE5A^UAS.cBa

(Vermehren-Schmaedick et al., 2011)

abnormal taste perception, with Gyc88E^GD11230

(Vermehren-Schmaedick et al., 2011)

lethal - all die before end of first instar larval stage, with Ctet\tetX^TNT-LC.UAS

(Morton et al., 2008)

some die during first instar larval stage, with Ctet\tetX^TNT-LC.UAS

(Morton et al., 2008)

viable, with Btau\PDE5A^UAS.cBa

(Vermehren-Schmaedick et al., 2010, Morton et al., 2008)

viable, with Ctet\tetX^IMPTNT-V.UAS

(Morton et al., 2008)

viable, with Gyc88E^GD11230

(Vermehren-Schmaedick et al., 2010)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^Gyc89Db.3.4/Gyc89Da^UAS.cVa is a suppressor of abnormal taste perception phenotype of Gyc89Db^MB03197

(Vermehren-Schmaedick et al., 2011)

Gyc89Db^UAS.cVa/Scer\GAL4^Gyc89Db.3.4 is a suppressor of abnormal stress response | third instar larval stage phenotype of Gyc89Da^e01821

(Vermehren-Schmaedick et al., 2010)

Scer\GAL4^Gyc89Db.3.4/Gyc89Da^UAS.cVa is a suppressor of abnormal stress response | third instar larval stage phenotype of Gyc89Db^MB03197

(Vermehren-Schmaedick et al., 2010)

NOT Suppressor of

Statement

Reference

Gyc89Db^UAS.cVa/Scer\GAL4^Gyc89Db.3.4 is a non-suppressor of abnormal taste perception phenotype of Gyc89Da^e01821

(Vermehren-Schmaedick et al., 2011)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^Gyc89Db.3.4/Gyc89Da^UAS.cVa rescues Gyc89Da^e01821

(Vermehren-Schmaedick et al., 2010)

Gyc89Db^UAS.cVa/Scer\GAL4^Gyc89Db.3.4 rescues Gyc89Db^MB03197

(Vermehren-Schmaedick et al., 2010)

Scer\GAL4^Gyc89Db.3.4/Gyc88E^UAS.cVa rescues Gyc88E^S451F/Gyc88E^V474M

(Vermehren-Schmaedick et al., 2010)

Fails to rescue

Scer\GAL4^Gyc89Db.3.4/Gyc89Da^UAS.cVa fails to rescue Gyc89Da^e01821

(Vermehren-Schmaedick et al., 2011)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

93113

y¹ w^*; P{Gyc89Db-GAL4.3.4}2

93556

y¹ w^*; P{Gyc89Db-GAL4.3.4}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Gyc-89Db^GAL4

(Vermehren-Schmaedick et al., 2010)

Scer\GAL4^Gyc-89Db.3.4

Scer\GAL4^Gyc89Db.3.4

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections