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General Information
Symbol
Dmel\PEKUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Malzer
FlyBase ID
FBal0248890
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-PERK, UAS-dPERK
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of PEK.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of PEKScer\UAS.cMa under the control of Scer\GAL4ppk.PU results dendritic arbor shortening in the class IV ddaC neurons.

Expression of PEKScer\UAS.cMa posterior to the morphogenetic furrow under the control of Scer\GAL4GMR.PF results in pupal lethality. Flies raised at 18[o]C emerge, and display a small, depigmented-eye phenotype.

In third instar eye imaginal discs expressing PEKScer\UAS.cMa under the control of Scer\GAL4GMR.PF, the second mitotic wave is less well defined compared to controls.

Eye disc mosaic clones expressing PEKScer\UAS.cMa under the control of Scer\GAL4αTub84B.PL (using the Gal80 system) show defects in the second wave of mitosis.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Phenotype Manifest In
Suppressed by
Statement
Reference

PEKUAS.cMa, Scer\GAL4GMR.PF has eye | temperature conditional phenotype, suppressible by grp[+]/grpGS.M

PEKUAS.cMa, Scer\GAL4GMR.PF has eye | temperature conditional phenotype, suppressible | partially by grpGD4189, Scer\GAL4GMR.PF

PEKUAS.cMa, Scer\GAL4GMR.PF has eye | temperature conditional phenotype, suppressible | partially by CycEUAS.cLa, Scer\GAL4GMR.PF

PEKUAS.cMa, Scer\GAL4GMR.PF has eye | temperature conditional phenotype, suppressible by Mmus\Ppp1r15aUAS.cMa, Scer\GAL4GMR.PF

Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of Gadd34Scer\UAS.cMa suppresses the eye defects caused by expression of PEKScer\UAS.cMa under the control of Scer\GAL4GMR.PF.

The small, depigmented-eye phenotype of flies expressing PEKScer\UAS.cMa under the control of Scer\GAL4GMR.PF is suppressed in a grpGS.M/+ background.

The small, depigmented-eye phenotype of flies expressing PEKScer\UAS.cMa under the control of Scer\GAL4GMR.PF is partially suppressed by co-expression of grpGD4189.

The small, depigmented-eye phenotype of flies expressing PEKScer\UAS.cMa under the control of Scer\GAL4GMR.PF is partially suppressed by co-expression of CycEScer\UAS.cLa.

Xenogenetic Interactions
Statement
Reference

Co-expression of Mmus\Ppp1r15aScer\UAS.cMa rescues the eye phenotype observed when PEKScer\UAS.cMa is expressed under the control of Scer\GAL4GMR.PF.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
PEKScer\UAS.cMa
PEKUAS.cMa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Malzer
Secondary FlyBase IDs
    References (7)