FlyBase Allele Report: Scer\GAL4[nompC.PP]

General Information

Symbol

Scer\GAL4^nompC.PP

Species

S. cerevisiae

Name

no mechanoreceptor potential C promoter construct of Petersen

FlyBase ID

FBal0263904

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{nompC-GAL4.P}

PBac{nompC-GAL4.P}

Also Known As

nompC-GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Petersen and Stowers, 2011)

Progenitor genotype

Carried in construct

P{nompC-GAL4.P}

PBac{nompC-GAL4.P}

Cytology

Description

GAL4 is expressed under the control of regulatory DNA from locations both upstream and downstream of the predicted translation start site of nompC.

(Petersen and Stowers, 2011)

Allele components

Component

Use(s)

Regulatory region(s)

nompC

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

larval multidendritic class III neuron

(Omamiuda-Ishikawa et al., 2020, Shearin et al., 2013, Tsubouchi et al., 2012)

larval abdominal lateral multidendritic neuron ldaB

(Petersen and Stowers, 2011)

abdominal dorsal multidendritic neuron ddaE

(Petersen and Stowers, 2011)

abdominal dorsal multidendritic neuron ddaA

(Petersen and Stowers, 2011)

abdominal dorsal multidendritic neuron ddaF

(Petersen and Stowers, 2011)

abdominal ventral multidendritic neuron v'dap

(Petersen and Stowers, 2011)

abdominal ventral multidendritic neuron vdaD

(Petersen and Stowers, 2011)

abdominal vch1 neuron

(Petersen and Stowers, 2011)

abdominal vch2 neuron

(Petersen and Stowers, 2011)

abdominal lch1 neuron

(Petersen and Stowers, 2011)

larval abdominal lch5 neuron

(Shearin et al., 2013, Petersen and Stowers, 2011)

chordotonal neuron

(Shearin et al., 2013)

vch1 neuron

(Shearin et al., 2013)

vch2 neuron

(Shearin et al., 2013)

lch1 neuron

(Shearin et al., 2013)

Additional Information

Statement

Reference

Drives expression in larval multidendritic class III neurons and chordotonal neurons.

(FlyBase Curators, 2017)

ScerGAL4^nompC.PP drives expression in larval multidendritic class III neurons and in larval scolopidial (chordotonal) neurons.

(Shearin et al., 2013)

ScerGAL4^nompC.PP drives expression in chordotonal organ and class III sensory neurons.

(Petersen and Stowers, 2011)

Marker for

larval multidendritic class III neuron

(Omamiuda-Ishikawa et al., 2020)

Reflects expression of

nompC

(Omamiuda-Ishikawa et al., 2020, Shearin et al., 2013, Tsubouchi et al., 2012, Petersen and Stowers, 2011)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Inhibition (using Ctet\TeTxLC^TNT.UAS) of Scer\GAL4^nompC.PP-expressing neurons severely decreases larval responses (rolling) to gentle touch.

(Yan et al., 2018)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Atat^UAS.L.GFP, Scer\GAL4^nompC.PP has abnormal touch response | larval stage phenotype, suppressible by αTub84B^K40A

(Yan et al., 2018)

Atat^UAS.L.GFP, Scer\GAL4^nompC.PP has abnormal touch perception | larval stage phenotype, suppressible by αTub84B^K40A

(Yan et al., 2018)

Suppressor of

Statement

Reference

Atat^UAS.L.GFP/Scer\GAL4^nompC.PP is a suppressor of abnormal touch response | larval stage phenotype of αTub84B^K40A

(Yan et al., 2018)

Atat^UAS.L.GFP/Scer\GAL4^nompC.PP is a suppressor of abnormal touch perception | larval stage phenotype of αTub84B^K40A

(Yan et al., 2018)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^nompC.PP/subdued^UAS.cJa rescues subdued^MI15535

(Himmel et al., 2023)

Atat^UAS.L.GFP/Scer\GAL4^nompC.PP rescues Atat^KO

(Yan et al., 2018)

Fails to rescue

Trpγ^UAS.cAa/Scer\GAL4^nompC.PP fails to rescue Trpγ¹

(Akitake et al., 2015)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

36361

y¹ w^*; PBac{nompC-GAL4.P}VK00014; Df(3L)Ly, sens^Ly-1/TM6C, Sb¹ Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Scer\GAL4^nompC.PP

nompC-GAL4

(Shearin et al., 2014)

Name Synonyms

no mechanoreceptor potential C promoter construct of Petersen

Secondary FlyBase IDs

References (28)

Report Sections

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