FlyBase Allele Report: Dmel\Su(z)2[sM]

General Information

Symbol

Dmel\Su(z)2^sM

Species

D. melanogaster

Name

FlyBase ID

FBal0282609

Feature type

allele

Associated gene

Dmel\Su(z)2

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

spontaneous

Nature of the Allele

Allele class

Mutagen

spontaneous

(Emmons et al., 2009)

Progenitor genotype

Cytology

Description

A missense mutation in the loop between the two Zn[++]-coordinating domains of the RF domain. This is predicted to destabilize the RF domain.

(Emmons et al., 2009)

Amino acid replacement: D49H.

(Emmons et al., 2009)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

2R:12,999,480..12,999,480 [+]

Nucleotide change:

G12999480C

Amino acid change:

D49H | Su(z)2-PA; D49H | Su(z)2-PB; D49H | Su(z)2-PC

Reported amino acid change:

D49H

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Emmons et al., 2009)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority die (with Su(z)2¹)

(Emmons et al., 2009)

partially lethal - majority die (with Su(z)2^s15)

(Emmons et al., 2009)

partially lethal - majority die (with Su(z)2^s21)

(Emmons et al., 2009)

viable

(Emmons et al., 2009)

viable (with Df(2R)Su(z)2-1.b8)

(Emmons et al., 2009)

viable (with Su(z)2^1.b7)

(Emmons et al., 2009)

viable (with Su(z)2^3-1)

(Emmons et al., 2009)

viable (with Su(z)2^4-31)

(Emmons et al., 2009)

viable (with Su(z)2^4-34)

(Emmons et al., 2009)

viable (with Su(z)2^e26)

(Emmons et al., 2009)

viable (with Su(z)2^eos)

(Emmons et al., 2009)

viable (with Su(z)2^h29)

(Emmons et al., 2009)

viable (with Su(z)2^s20)

(Emmons et al., 2009)

viable (with Su(z)2^s36)

(Emmons et al., 2009)

viable (with Su(z)2^s84)

(Emmons et al., 2009)

viable (with Su(z)2^s95)

(Emmons et al., 2009)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Su(z)2^sM/Su(z)2[+] is a non-enhancer of abnormal eye color phenotype of w^RNAi.GMR

(Ji et al., 2012)

NOT Suppressor of

Statement

Reference

Su(z)2^sM/Su(z)2[+] is a non-suppressor of abnormal eye color phenotype of w^RNAi.GMR

(Ji et al., 2012)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Arose spontaneously in a Canton-S stock.

(Emmons et al., 2009)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Su(z)2^sM

(Ji et al., 2012, Emmons et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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