FlyBase Allele Report: Scer\GAL4[wor.PU]

General Information

Symbol

Scer\GAL4^wor.PU

Species

S. cerevisiae

Name

FlyBase ID

FBal0301590

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{wor-GAL4.U}

Also Known As

wor-Gal4, Worniu-Gal4, worGal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{wor-GAL4.U}

Cytology

Description

wor sequences control expression of a GAL4 driver.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

wor

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell size | larval stage, with Sdc^GD4545

(Eldridge-Thomas et al., 2025)

abnormal mitotic cell cycle | larval stage, with Sdc^GD4545

(Eldridge-Thomas et al., 2025)

abnormal mitotic cell cycle | third instar larval stage, with Wdr62^UAS.Dendra2

(Ramdas Nair et al., 2016)

abnormal neuroanatomy | adult stage, with Iswi^HMS00628

(Gong et al., 2021)

abnormal neuroanatomy | larval stage, with IntS1^GD10348, Scer\GAL80^ase.PN

(Zhang et al., 2019)

abnormal neuroanatomy | larval stage, with IntS2^KK100750, Scer\GAL80^ase.PN

(Zhang et al., 2019)

abnormal neuroanatomy | larval stage, with IntS8^KK102901, Scer\GAL80^ase.PN

(Zhang et al., 2019)

abnormal neuroanatomy | larval stage, with Opa1^HMS00349

(Dubal et al., 2022)

abnormal neuroanatomy | larval stage, with Scer\GAL80^ase.PN, erm^JF02342

(Zhang et al., 2019)

abnormal size | larval stage, with Sdc^GD4545

(Eldridge-Thomas et al., 2025)

abnormal sleep | adult stage, with Iswi^HMS00628

(Gong et al., 2021)

decreased cell number | larval stage, with Opa1^HMS00349

(Dubal et al., 2022)

decreased cell size | larval stage, with dre4^HMS01332

(Lou et al., 2024)

decreased cell size | larval stage, with Ssrp^JF02120

(Lou et al., 2024)

decreased occurrence of cell division | larval stage, with Opa1^HMS00349

(Dubal et al., 2022)

decreased occurrence of cell division | larval stage, with Ssrp^JF02120

(Lou et al., 2024)

decreased rate of adult locomotory behavior, with dre4^HMS01332

(Lou et al., 2024)

decreased rate of adult locomotory behavior, with Ssrp^JF02120

(Lou et al., 2024)

decreased rate of movement | adult stage, with Marf^RNAi.UTR.UAS

(Dubal et al., 2022)

decreased rate of movement | adult stage, with Opa1^HMS00349

(Dubal et al., 2022)

decreased sleep | adult stage, with Iswi^HMS00628

(Gong et al., 2021)

fertile, with Nin^UASp.EGFP

(Zheng et al., 2016)

increased cell number | adult stage, with Ssrp^JF02120

(Lou et al., 2024)

increased cell number | larval stage, with IntS1^GD10348, Scer\GAL80^ase.PN

(Zhang et al., 2019)

increased cell number | larval stage, with IntS2^KK100750, Scer\GAL80^ase.PN

(Zhang et al., 2019)

increased cell number | larval stage, with IntS8^KK102901, Scer\GAL80^ase.PN

(Zhang et al., 2019)

increased cell number | larval stage, with Scer\GAL80^ase.PN, erm^JF02342

(Zhang et al., 2019)

increased cell number | P-stage, with Ssrp^JF02120

(Lou et al., 2024)

increased occurrence of cell division | larval stage, with Marf^RNAi.UTR.UAS

(Dubal et al., 2022)

lethal - all die before end of P-stage, with Marf^{RNAi.CDS.UAS.cSa}

(Dubal et al., 2022)

lethal - all die before end of P-stage, with Marf^RNAi.UTR.UAS

(Dubal et al., 2022)

lethal - all die before end of P-stage, with Opa1^HMS00349

(Dubal et al., 2022)

lethal - all die before end of P-stage, with Opa1^RNAi.CDS.UAS

(Dubal et al., 2022)

short lived, with dre4^HMS01332

(Lou et al., 2024)

short lived, with ERR^UAS.cTa

(Lou et al., 2024)

short lived, with Ssrp^JF02120

(Lou et al., 2024)

viable, with Nin^UASp.EGFP

(Zheng et al., 2016)

Phenotype Manifest In

adult mushroom body, with Iswi^HMS00628

(Gong et al., 2021)

larval brain | larval stage, with Marf^RNAi.UTR.UAS

(Dubal et al., 2022)

larval brain | larval stage, with Opa1^HMS00349

(Dubal et al., 2022)

larval central brain, with Ssrp^JF02120

(Lou et al., 2024)

larval neuroblast, with dre4^HMS01332

(Lou et al., 2024)

larval neuroblast, with Sdc^GD4545

(Eldridge-Thomas et al., 2025)

larval neuroblast, with Ssrp^JF02120

(Lou et al., 2024)

larval neuron | decreased number | larval stage, with Opa1^HMS00349

(Dubal et al., 2022)

microtubule | third instar larval stage, with Wdr62^UAS.Dendra2

(Ramdas Nair et al., 2016)

neuroblast | adult stage | ectopic, with Ssrp^JF02120

(Lou et al., 2024)

neuroblast | P-stage | increased number, with Ssrp^JF02120

(Lou et al., 2024)

neuroblast | third instar larval stage, with Wdr62^UAS.Dendra2

(Ramdas Nair et al., 2016)

nuclear envelope | larval stage, with Sdc^GD4545

(Eldridge-Thomas et al., 2025)

nucleus | larval stage, with Sdc^GD4545

(Eldridge-Thomas et al., 2025)

type II neuroblast | larval stage, with Marf^RNAi.UTR.UAS

(Dubal et al., 2022)

type II neuroblast | larval stage, with Opa1^HMS00349

(Dubal et al., 2022)

type II neuroblast | larval stage, with Scer\GAL80^ase.PN, erm^JF02342

(Zhang et al., 2019)

type II neuroblast | larval stage | increased number, with IntS1^GD10348, Scer\GAL80^ase.PN

(Zhang et al., 2019)

type II neuroblast | larval stage | increased number, with IntS2^KK100750, Scer\GAL80^ase.PN

(Zhang et al., 2019)

type II neuroblast | larval stage | increased number, with IntS8^KK102901, Scer\GAL80^ase.PN

(Zhang et al., 2019)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

IntS8^KK102901, Scer\GAL4^wor.PU, Scer\GAL80^ase.PN has increased cell number | larval stage phenotype, enhanceable by erm^JF02342, Scer\GAL4^wor.PU, Scer\GAL80^ase.PN

(Zhang et al., 2019)

IntS8^KK102901, Scer\GAL4^wor.PU, Scer\GAL80^ase.PN has abnormal neuroanatomy | larval stage phenotype, enhanceable by erm^JF02342, Scer\GAL4^wor.PU, Scer\GAL80^ase.PN

(Zhang et al., 2019)

Suppressed by

Statement

Reference

Scer\GAL4^wor.PU, Ssrp^JF02120 has short lived phenotype, suppressible | partially by ERR^UAS.cTa, Scer\GAL4^wor.PU

(Lou et al., 2024)

Scer\GAL4^wor.PU, Ssrp^JF02120 has decreased rate of adult locomotory behavior phenotype, suppressible | partially by ERR^UAS.cTa, Scer\GAL4^wor.PU

(Lou et al., 2024)

Scer\GAL4^wor.PU, Ssrp^JF02120 has increased cell number | adult stage phenotype, suppressible | partially by ERR^UAS.cTa, Scer\GAL4^wor.PU

(Lou et al., 2024)

Scer\GAL4^wor.PU, Ssrp^JF02120 has increased cell number | adult stage phenotype, suppressible by Scer\GAL4^wor.PU/UQCR-11^TH04741.N

(Lou et al., 2024)

Scer\GAL4^wor.PU, Ssrp^JF02120 has increased cell number | adult stage phenotype, suppressible | partially by mt:CoII^TH04769.N/Scer\GAL4^wor.PU

(Lou et al., 2024)

Scer\GAL4^wor.PU, Ssrp^JF02120 has short lived phenotype, suppressible | partially by mt:CoII^TH04769.N/Scer\GAL4^wor.PU

(Lou et al., 2024)

Scer\GAL4^wor.PU, Ssrp^JF02120 has short lived phenotype, suppressible | partially by Scer\GAL4^wor.PU/UQCR-11^TH04741.N

(Lou et al., 2024)

Scer\GAL4^wor.PU, Ssrp^JF02120 has decreased rate of adult locomotory behavior phenotype, suppressible | partially by mt:CoII^TH04769.N/Scer\GAL4^wor.PU

(Lou et al., 2024)

Scer\GAL4^wor.PU, Ssrp^JF02120 has decreased rate of adult locomotory behavior phenotype, suppressible | partially by Scer\GAL4^wor.PU/UQCR-11^TH04741.N

(Lou et al., 2024)

Marf^RNAi.UTR.UAS, Scer\GAL4^wor.PU has increased occurrence of cell division | larval stage phenotype, suppressible | partially by Drp1^SD.UASp, Scer\GAL4^wor.PU

(Dubal et al., 2022)

Opa1^HMS00349, Scer\GAL4^wor.PU has decreased occurrence of cell division | larval stage phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^wor.PU

(Dubal et al., 2022)

Enhancer of

Statement

Reference

Scer\GAL80^ase.PN, erm^JF02342, Scer\GAL4^wor.PU is an enhancer of increased cell number | larval stage phenotype of IntS8^KK102901, Scer\GAL4^wor.PU, Scer\GAL80^ase.PN

(Zhang et al., 2019)

Scer\GAL80^ase.PN, erm^JF02342, Scer\GAL4^wor.PU is an enhancer of abnormal neuroanatomy | larval stage phenotype of IntS8^KK102901, Scer\GAL4^wor.PU, Scer\GAL80^ase.PN

(Zhang et al., 2019)

Suppressor of

Statement

Reference

ERR^UAS.cTa, Scer\GAL4^wor.PU is a suppressor | partially of short lived phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

ERR^UAS.cTa, Scer\GAL4^wor.PU is a suppressor | partially of decreased rate of adult locomotory behavior phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

ERR^UAS.cTa, Scer\GAL4^wor.PU is a suppressor | partially of increased cell number | adult stage phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

Scer\GAL4^wor.PU/UQCR-11^TH04741.N is a suppressor of increased cell number | adult stage phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

mt:CoII^TH04769.N/Scer\GAL4^wor.PU is a suppressor | partially of increased cell number | adult stage phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

mt:CoII^TH04769.N/Scer\GAL4^wor.PU is a suppressor | partially of short lived phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

Scer\GAL4^wor.PU/UQCR-11^TH04741.N is a suppressor | partially of short lived phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

mt:CoII^TH04769.N/Scer\GAL4^wor.PU is a suppressor | partially of decreased rate of adult locomotory behavior phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

Scer\GAL4^wor.PU/UQCR-11^TH04741.N is a suppressor | partially of decreased rate of adult locomotory behavior phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

Drp1^SD.UASp, Scer\GAL4^wor.PU is a suppressor | partially of increased occurrence of cell division | larval stage phenotype of Marf^RNAi.UTR.UAS, Scer\GAL4^wor.PU

(Dubal et al., 2022)

Drp1^SD.UASp, Scer\GAL4^wor.PU is a suppressor of decreased occurrence of cell division | larval stage phenotype of Opa1^HMS00349, Scer\GAL4^wor.PU

(Dubal et al., 2022)

Scer\GAL4^wor.PU, Scer\GAL80^ase.PN, erm^UAS.Tag:HA is a suppressor of abnormal cell number | somatic clone | larval stage phenotype of IntS8^SH1314

(Zhang et al., 2019)

Scer\GAL4^wor.PU, Scer\GAL80^ase.PN, erm^UAS.Tag:HA is a suppressor of abnormal neuroanatomy | somatic clone | larval stage phenotype of IntS8^SH1314

(Zhang et al., 2019)

Phenotype Manifest In

Enhanced by

Statement

Reference

IntS8^KK102901, Scer\GAL4^wor.PU, Scer\GAL80^ase.PN has type II neuroblast | larval stage | increased number phenotype, enhanceable by erm^JF02342, Scer\GAL4^wor.PU, Scer\GAL80^ase.PN

(Zhang et al., 2019)

Suppressed by

Statement

Reference

Scer\GAL4^wor.PU, Ssrp^JF02120 has neuroblast | ectopic | adult stage phenotype, suppressible | partially by ERR^UAS.cTa, Scer\GAL4^wor.PU

(Lou et al., 2024)

Scer\GAL4^wor.PU, Ssrp^JF02120 has neuroblast | ectopic | adult stage phenotype, suppressible by Scer\GAL4^wor.PU/UQCR-11^TH04741.N

(Lou et al., 2024)

Scer\GAL4^wor.PU, Ssrp^JF02120 has neuroblast | ectopic | adult stage phenotype, suppressible | partially by mt:CoII^TH04769.N/Scer\GAL4^wor.PU

(Lou et al., 2024)

Marf^RNAi.UTR.UAS, Scer\GAL4^wor.PU has larval brain | larval stage phenotype, suppressible | partially by Drp1^SD.UASp, Scer\GAL4^wor.PU

(Dubal et al., 2022)

Marf^RNAi.UTR.UAS, Scer\GAL4^wor.PU has type II neuroblast | larval stage phenotype, suppressible | partially by Drp1^SD.UASp, Scer\GAL4^wor.PU

(Dubal et al., 2022)

Opa1^HMS00349, Scer\GAL4^wor.PU has type II neuroblast | larval stage phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^wor.PU

(Dubal et al., 2022)

Enhancer of

Statement

Reference

Scer\GAL80^ase.PN, erm^JF02342, Scer\GAL4^wor.PU is an enhancer of type II neuroblast | larval stage | increased number phenotype of IntS8^KK102901, Scer\GAL4^wor.PU, Scer\GAL80^ase.PN

(Zhang et al., 2019)

Suppressor of

Statement

Reference

ERR^UAS.cTa, Scer\GAL4^wor.PU is a suppressor | partially of neuroblast | ectopic | adult stage phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

Scer\GAL4^wor.PU/UQCR-11^TH04741.N is a suppressor of neuroblast | ectopic | adult stage phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

mt:CoII^TH04769.N/Scer\GAL4^wor.PU is a suppressor | partially of neuroblast | ectopic | adult stage phenotype of Scer\GAL4^wor.PU, Ssrp^JF02120

(Lou et al., 2024)

Drp1^SD.UASp, Scer\GAL4^wor.PU is a suppressor | partially of larval brain | larval stage phenotype of Marf^RNAi.UTR.UAS, Scer\GAL4^wor.PU

(Dubal et al., 2022)

Drp1^SD.UASp, Scer\GAL4^wor.PU is a suppressor | partially of type II neuroblast | larval stage phenotype of Marf^RNAi.UTR.UAS, Scer\GAL4^wor.PU

(Dubal et al., 2022)

Drp1^SD.UASp, Scer\GAL4^wor.PU is a suppressor of type II neuroblast | larval stage phenotype of Opa1^HMS00349, Scer\GAL4^wor.PU

(Dubal et al., 2022)

Scer\GAL4^wor.PU, Scer\GAL80^ase.PN, erm^UAS.Tag:HA is a suppressor of type II neuroblast | increased number | somatic clone | larval stage phenotype of IntS8^SH1314

(Zhang et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^wor.PU/Ssrp^{UAS.ORF.GW.Tag:HA} rescues Ssrp^JF02120

(Lou et al., 2024)

Scer\GAL4^wor.PU, Scer\GAL80^ase.PN, omd^UAS.cZa rescues omd³⁴⁸

(Zhang et al., 2019)

Scer\GAL4^wor.PU, Scer\GAL80^ase.PN, omd^UAS.cZa rescues omd¹²⁶

(Zhang et al., 2019)

Scer\GAL4^wor.PU/Wdr62^UAS.Dendra2 rescues Df(2L)Exel8005/Wdr62^Δ2a

(Ramdas Nair et al., 2016)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^wor.PU

Name Synonyms

Secondary FlyBase IDs

References (30)

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