FlyBase Allele Report: Scer\GAL4[Ret.P2]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Scer\GAL4^Ret.P2

General Information

Symbol

Scer\GAL4^Ret.P2

Species

S. cerevisiae

Name

FlyBase ID

FBal0305158

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Hernández et al., 2015)

Progenitor genotype

Carried in construct

Cytology

Description

Ret promoter sequences control expression of a GAL4 driver.

(Hernández et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

Encoded product / tool

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

precursor cell of the stomatogastric nervous system

(Hernández et al., 2015)

embryonic stage 13 -- 16

invaginating stomatogastric nervous system precursor

(Hernández et al., 2015)

embryonic stage 17 -- first instar larval stage

proventricular ganglion

(Hernández et al., 2015)

second instar larval stage

proventriculus | posterior to

(Hernández et al., 2015)

Additional Information

Statement

Reference

ScerGAL4^Ret.P2 drives expression in the developing somatogastric nervous system migrating clusters, starting at embryonic stage 11/12 (pre-migration) through embryonic stage 16, and in the proventricular ganglion through in the first larval instar. ScerGAL4^Ret.P2 also drives expression in a few cells in the embryonic brain, in the embryonic gut, and in cells posterior to the proventriculus in second instar larvae.

(Hernández et al., 2015)

Marker for

Reflects expression of

(Hernández et al., 2015)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell migration | embryonic stage, with Ret^KK107206

(Myers et al., 2018)

abnormal neuroanatomy, with Egfr^DN.UAS.cBa

(Hernández et al., 2015)

abnormal neuroanatomy | embryonic stage, with Dscam1^{UAS.1.30.30.2}

(Hernández et al., 2023)

abnormal neuroanatomy | embryonic stage, with Dscam1^{ΔC.UAS.1.30.30.1.GFP}

(Hernández et al., 2023)

abnormal neuroanatomy | embryonic stage, with Pak^{UAS.Tag:Myr(Src64B)}

(Hernández et al., 2023)

abnormal neuroanatomy | embryonic stage, with Pak^UASp.GFP

(Hernández et al., 2023)

abnormal neuroanatomy | embryonic stage, with Ret^KK107206

(Myers et al., 2018)

abnormal size | embryonic stage, with Ret^KK107206

(Myers et al., 2018)

decreased rate of larval locomotory behavior, with Dscam1^{UAS.1.30.30.2}

(Hernández et al., 2023)

increased rate of larval locomotory behavior, with Dscam1^{ΔC.UAS.1.30.30.1.GFP}

(Hernández et al., 2023)

increased size | embryonic stage, with Dscam1^{UAS.1.30.30.2}

(Hernández et al., 2023)

increased size | embryonic stage, with Pak^UASp.GFP

(Hernández et al., 2023)

Phenotype Manifest In

embryonic/larval frontal nerve, with Egfr^DN.UAS.cBa

(Hernández et al., 2015)

embryonic/larval frontal nerve | absent | embryonic stage, with Dscam1^{ΔC.UAS.1.30.30.1.GFP}

(Hernández et al., 2023)

embryonic/larval frontal nerve | absent | embryonic stage, with Pak^{UAS.Tag:Myr(Src64B)}

(Hernández et al., 2023)

embryonic/larval frontal nerve | embryonic stage, with Dscam1^{UAS.1.30.30.2}

(Hernández et al., 2023)

embryonic/larval frontal nerve | embryonic stage, with Pak^UASp.GFP

(Hernández et al., 2023)

embryonic/larval frontal nerve | embryonic stage, with Ret^KK107206

(Myers et al., 2018)

embryonic/larval hypocerebral ganglion | embryonic stage, with Ret^KK107206

(Myers et al., 2018)

embryonic/larval recurrent nerve, with Egfr^DN.UAS.cBa

(Hernández et al., 2015)

embryonic/larval recurrent nerve | embryonic stage, with Ret^KK107206

(Myers et al., 2018)

embryonic frontal ganglion, with Ret^KK107206

(Myers et al., 2018)

larval hindgut nerve | embryonic stage, with Dscam1^{UAS.1.30.30.2}

(Hernández et al., 2023)

larval hindgut nerve | embryonic stage, with Dscam1^{ΔC.UAS.1.30.30.1.GFP}

(Hernández et al., 2023)

larval hindgut nerve | embryonic stage, with Pak^{UAS.Tag:Myr(Src64B)}

(Hernández et al., 2023)

larval hindgut nerve | embryonic stage, with Pak^UASp.GFP

(Hernández et al., 2023)

paraesophageal ganglion | embryonic stage, with Ret^KK107206

(Myers et al., 2018)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

Scer\GAL4^Ret.P2/Sarm^GD12314 is a non-suppressor of nerve | larval stage phenotype of Ret^LM1

(Myers et al., 2018)

Scer\GAL4^Ret.P2/Sarm^GD12314 is a non-suppressor of axon | larval stage phenotype of Ret^LM1

(Myers et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

Ret^{UAS.Tag:FLAG,Tag:polyHis}/Scer\GAL4^Ret.P2 partially rescues Ret^LM1

(Myers et al., 2018)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

84239

w^*; sna^Sco/CyO; P{Ret-GAL4.P2}attP2-A

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^Ret.P2

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections