FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\rt
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General Information
Symbol
Dmel\rt
Species
D. melanogaster
Name
rotated abdomen
Annotation Symbol
CG6097
Feature Type
protein_coding_gene
FlyBase ID
FBgn0003292
Gene Model Status
Current
Stock Availability
18 publicly available
Enzyme Name (EC)
dolichyl-phosphate-mannose--protein mannosyltransferase (2.4.1.109)
Gene Summary
rotated abdomen (rt) encodes an endoplasmic reticulum transmembrane protein O-mannosyltransferase that, together with the tw protein, catalyzes the attachment of D-mannose to the hydroxyl group of serine or threonine in secreted or membrane proteins via an α-glycosidic bond. O-mannosylation of proteins such as dystroglycan Dg plays an important role in myogenesis, muscle architecture and cell adhesion. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)
All Summaries
Also Known As

POMT1, dPOMT1

Key Links
Genomic Location
Cytogenetic map
68C13-68C13
Sequence location
Recombination map
3-36
RefSeq locus
NT_037436 REGION:11584122..11587770
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (14 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
contributes_to dolichyl-phosphate-mannose-protein mannosyltransferase activity
inferred from direct assay
(Nakamura et al., 2010, Ueyama et al., 2010, Ichimiya et al., 2004)
inferred from mutant phenotype
(Monagas-Valentin et al., 2023)
enables protein binding
inferred from physical interaction with UniProtKB:Q9W5D4
(Lyalin et al., 2006, Ichimiya et al., 2004)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables mannosyltransferase activity
inferred from electronic annotation with InterPro:IPR003342
(InterPro Project Members, 2004-)
Biological Process (7 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
involved_in muscle organ development
inferred from mutant phenotype
(Lyalin et al., 2006)
involved_in protein O-linked glycosylation via mannose
inferred from direct assay
(Nakamura et al., 2010, Ichimiya et al., 2004)
involved_in regulation of synaptic activity
inferred from mutant phenotype
(Wairkar et al., 2008)
involved_in sarcomere organization
inferred from genetic interaction with FLYBASE:Dg; FB:FBgn0034072
(Haines et al., 2007)
involved_in somatic muscle development
inferred from mutant phenotype
(Ueyama et al., 2010)
involved_in specification of segmental identity, abdomen
inferred from mutant phenotype
(Martin-Blanco and Garcia-Bellido, 1996)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in protein O-linked glycosylation via mannose
inferred from biological aspect of ancestor with PANTHER:PTN008936969
(GO Reference Genome Project, 2011-)
involved_in protein O-linked glycosylation
inferred from electronic annotation with InterPro:IPR003342
(InterPro Project Members, 2004-)
Cellular Component (4 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
part_of dolichyl-phosphate-mannose-protein mannosyltransferase complex
inferred from direct assay
(Ichimiya et al., 2004)
located_in endoplasmic reticulum membrane
inferred from direct assay
(Lyalin et al., 2006)
located_in endoplasmic reticulum
inferred from direct assay
(Lyalin et al., 2006)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
is_active_in endoplasmic reticulum
inferred from biological aspect of ancestor with PANTHER:PTN001295889
(GO Reference Genome Project, 2011-)
located_in membrane
inferred from electronic annotation with InterPro:IPR003342
(InterPro Project Members, 2004-)
Gene Group (FlyBase)
Pathway (FlyBase)
Protein Family (UniProt)
Belongs to the glycosyltransferase 39 family. (Q9VTK2)
Protein Signatures (InterPro)
Catalytic Activity (EC/Rhea)
dolichyl-phosphate-mannose-protein mannosyltransferase activity
(1) a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl- [protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly- cis-dolichyl phosphate + H(+) (2.4.1.109)
(2) a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl- [protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+) (2.4.1.109)
Summaries
Gene Snapshot
rotated abdomen (rt) encodes an endoplasmic reticulum transmembrane protein O-mannosyltransferase that, together with the tw protein, catalyzes the attachment of D-mannose to the hydroxyl group of serine or threonine in secreted or membrane proteins via an α-glycosidic bond. O-mannosylation of proteins such as dystroglycan Dg plays an important role in myogenesis, muscle architecture and cell adhesion. [Date last reviewed: 2019-03-14]
Gene Group (FlyBase)
PROTEIN O-MANNOSYLTRANSFERASES -
Protein O-mannosyltransferases transfer a mannose residue from dolichyl phosphate D-mannose to the oxygen atom of the hydroxyl group of selected serine/threonine residues. In contrast to yeast, O-Man glycosylation in metazoans is found only on select proteins. The evolutionary conserved POMT1/POMT2 enzymes target the dystroglycan protein, while the TMTC proteins selectively serve cadherins and protocadherins. (Adapted from PMID:28973932 and FBrf0244700.) These enzymes are localized in the endoplasmic reticulum.
POMT1-POMT2 COMPLEX -
The POMT1-POMT2 complex is a heterodimeric mannosyltransferase complex that transfers a mannose residue from dolichyl phosphate D-mannose to the oxygen atom of the hydroxyl group of selected serine/threonine residues of the dystroglycan protein. (Adapted from PMID:31285605 and FBrf0244700).
Pathway (FlyBase)
PROTEIN O-MANNOSYLATION -
Protein O-linked mannosylation is a post-translational modification that occurs in the endoplasmic reticulum and is characterized by the attachment of a mannose to the hydroxyl group of serine or threonine residues of selected proteins via an α-glycosidic bond. In D. melanogaster, O-linked mannose is not further elongated to form more complex glycan structures. Mannosyltransferases rt and tw act together as a complex to O-mannosylate proteins such as dystroglycan Dg, while Tmtc1, Tmtc2, Tmtc3 and Tmtc4 are thought to specifically O-mannosylate cadherins. (Adapted from FBrf0258752.)
Protein Function (UniProtKB)
Rt/POMT1 and tw/POMT2 function as a protein O-mannosyltransferase in association with each other to generate and maintain normal muscle development.
(UniProt, Q9VTK2)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
*rt: rotated abdomen
Abdomen twisted clockwise through 60 to 90, as viewed from behind. Both sexes sterile. Viability low. RK2.
rt2
Abdomen twisted, as is rt. Viability erratic, usually about 50% wild type. Male fertile; female not tested. RK2.
*rtW: rotated abdomen of Wallbrunn
Like rt. RK2.
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\rt for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9VTK2)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.50

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
rt-RA
FBtr0076146
NM_079301
3268
886
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
rt-PA
FBpp0075877
101.2
886
9.36
Q9VTK2
NP_524025
AAF50046
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Subunit Structure (UniProtKB)

Interacts with tw/POMT2.

(UniProt, Q9VTK2)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\rt using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.63

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 10
organism | faint
(Ichimiya et al., 2004)
germ band | intense
(Ichimiya et al., 2004)
early stomodeal invagination | intense
(Ichimiya et al., 2004)
hindgut proper primordium | intense
(Ichimiya et al., 2004)
posterior midgut primordium | intense
(Ichimiya et al., 2004)
embryonic stage 14
embryonic/larval epidermis
(Lyalin et al., 2006)
embryonic/larval hindgut
(Lyalin et al., 2006)
embryonic/larval foregut
(Lyalin et al., 2006)
embryonic stage 15
embryonic/larval tracheal section
(Lyalin et al., 2006)
Additional Descriptive Data

rt maternal transcripts are observed at embryonic stages 5-7. From stage 14 rt expression is observed in developing epidermal cells as well as in hindgut and foregut. It is also present in developing trachea starting in stage 15.

(Lyalin et al., 2006)

At embryonic stage 10, intense expression of rt is observed in the germ band and in the invaginating gut. Faint but steady expression is observed in all cells of the stage 10 embryo.

(Ichimiya et al., 2004)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
part_of dolichyl-phosphate-mannose-protein mannosyltransferase complex
inferred from direct assay
(Ichimiya et al., 2004)
located_in endoplasmic reticulum membrane
inferred from direct assay
(Lyalin et al., 2006)
located_in endoplasmic reticulum
inferred from direct assay
(Lyalin et al., 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\rt in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 25 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 10 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of rt
Transgenic constructs containing regulatory region of rt
Aberrations (Deficiencies and Duplications) ( 18 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal, with Scer\GAL4Act5C.PU
lethal | heat sensitive, with Scer\GAL4Act5C.PHb
lethal | heat sensitive, with Scer\GAL4Act5C.PU
lethal | recessive
partially lethal
Sterility
Allele
female semi-fertile
female sterile
female sterile | recessive
male semi-fertile
male sterile
Other Phenotypes
Allele
abnormal flight (with rtEP571)
abnormal flight (with rtKG04772)
abnormal locomotor behavior | adult stage, with Scer\GAL4Act5C.PU
abnormal locomotor behavior | adult stage (with rtEP571)
abnormal locomotor behavior | adult stage (with rtKG04772)
abnormal neurophysiology (with Df(3L)ED4470)
short lived, with Scer\GAL4Act5C.PU
visible | recessive
Phenotype manifest in
Allele
abdomen
adult abdomen
adult abdomen, with Scer\GAL4Act5C.PHb
adult abdomen (with rt2)
adult abdomen (with rtEP571)
adult abdomen (with rtP)
adult cuticle
larval muscle system | third instar larval stage
larval muscle system | third instar larval stage (with rt2)
larval muscle system | third instar larval stage (with rtP)
larval somatic muscle cell
larval somatic muscle cell (with rtEP571)
larval somatic muscle cell (with rtKG04772)
larval somatic muscle cell | lateral
muscle attachment site | third instar larval stage
muscle attachment site | third instar larval stage (with rt2)
muscle attachment site | third instar larval stage (with rtP)
sarcomere | third instar larval stage
sarcomere | third instar larval stage (with rt2)
sarcomere | third instar larval stage (with rtP)
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (5)
Hsap\POMT1
11 of 14
Yes
Yes
Hsap\POMT2
3 of 14
No
No
Hsap\SDF2
2 of 14
No
No
1  
Hsap\SDF2L1
2 of 14
No
No
1  
Hsap\ITPR2
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (5)
Rnor\Pomt1
12 of 14
Yes
Yes
Rnor\Pomt2
3 of 14
No
No
Rnor\Sdf2l1
2 of 14
No
No
Rnor\Sdf2
2 of 14
No
No
Rnor\Itpr2
1 of 14
No
No
Mus musculus (laboratory mouse) (5)
Mmus\Pomt1
11 of 14
Yes
Yes
Mmus\Pomt2
3 of 14
No
No
Mmus\Sdf2l1
2 of 14
No
No
Mmus\Sdf2
2 of 14
No
No
Mmus\Itpr2
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (3)
Xtro\pomt1
8 of 13
Yes
Yes
Xtro\pomt2
2 of 13
No
No
Xtro\sdf2
1 of 13
No
No
Danio rerio (Zebrafish) (4)
Drer\pomt1
12 of 14
Yes
Yes
Drer\pomt2
3 of 14
No
No
Drer\sdf2
2 of 14
No
No
Drer\sdf2l1
2 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\R12E2.13
2 of 14
Yes
No
Anopheles gambiae (African malaria mosquito) (3)
Agam\AgaP_AGAP010784
12 of 12
Yes
Yes
Agam\AgaP_AGAP002674
3 of 12
No
No
Agam\AgaP_AGAP001749
2 of 12
No
No
Arabidopsis thaliana (thale-cress) (1)
Atha\SDF2
2 of 13
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (7)
Scer\PMT4
11 of 13
Yes
Yes
Scer\PMT1
4 of 13
No
Yes
Scer\PMT5
4 of 13
No
Yes
Scer\PMT2
3 of 13
No
No
Scer\PMT3
3 of 13
No
No
Scer\PMT6
3 of 13
No
No
Scer\PMT7
3 of 13
No
Yes
Schizosaccharomyces pombe (Fission yeast) (3)
Spom\ogm4
11 of 12
Yes
Yes
Spom\ogm1
3 of 12
No
No
Spom\ogm2
3 of 12
No
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:rt. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (2)
tw
5 of 13
CG11999
3 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 5 )
Potential Models Based on Orthology ( 3 )
Modifiers Based on Experimental Evidence ( 2 )
Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
POMT1; protein O-mannosyltransferase 1
11 of 14
607423
POMT2; protein O-mannosyltransferase 2
3 of 14
607439
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
Interactions
Summary of Physical Interactions
Summary of Genetic Interactions
Interaction Browsers
View in FlyBase Interactions Browser   View in MIST tool (external link)
Please look at the allele data for full details of the genetic interactions
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
rt
suppressible
tw
(Lyalin et al., 2006)
rt
enhanceable
tw
(Haines et al., 2007)
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
Dg
enhanceable
tw|rt
(Nakamura et al., 2010)
Dg
enhanceable
rt
(Ueyama et al., 2010)
PIG-A
enhanceable
rt
(Thorpe et al., 2025)
External Data
Subunit Structure (UniProtKB)
Interacts with tw/POMT2.
(UniProt, Q9VTK2 )
Linkouts
DroID - A comprehensive database of gene and protein interactions.
MIST (genetic) - An integrated Molecular Interaction Database
Pathways
Signaling Pathways (FlyBase)
Metabolic Pathways
FlyBase
PROTEIN O-MANNOSYLATION
External Links
FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.
External Data
Linkouts
KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
Class of Gene
Genomic Location and Detailed Mapping Data
Chromosome (arm)
3L
Recombination map
3-36
Cytogenetic map
68C13-68C13
Sequence location
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
68C13-68C13
Limits computationally determined from genome sequence between P{PZ}l(3)0123901239&P{lacW}l(3)01239j9B4 and P{PZ}CycA02461&P{PZ}CycA03946
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
69B-69B
(Martin-Blanco, 1996.2.27)
68C1-68C8
(determined by in situ hybridisation)
(Spradling et al., 1999)
68C1-68C8
(BDGP Project Members, 1994-1999)
68C-68C
(determined by in situ hybridisation)
(Cooley et al., 1988)
Experimentally Determined Recombination Data
Location

3-36

(FlyBase, 2016)

3-30.0

(Comeron et al., 2012)

3-37

Left of (cM)
Right of (cM)
Notes

Mapping based on location of rt2.

Stocks and Reagents
Stocks (18)
Genomic Clones (12)
 

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (127)
 

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced
BDGP DGC clones
    Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
        Other clones
          RNAi and Array Information
          Linkouts
          DRSC - Results frm RNAi screens
          Antibody Information
          Laboratory Generated Antibodies
           
          Commercially Available Antibodies
           
          Cell Line Information
          Publicly Available Cell Lines
           
            Other Stable Cell Lines
             
              Other Comments
              Relationship to Other Genes
              Source for database merge of
              Additional comments
              Nomenclature History
              Source for database identify of

              Source for identity of: rt CG6097

              (Zhang, 1999.11)
              Nomenclature comments
              Etymology

              The gene is named "rotated abdomen" after the mutant phenotype; mutant flies have a clockwise twisted abdomen.

              (Ichimiya et al., 2004)
              Synonyms and Secondary IDs (16)
              Datasets (0)
              Study focus (0)
              Experimental Role
              Project
              Project Type
              Title
              Study result (0)
              Result
              Result Type
              Title
              External Crossreferences and Linkouts ( 54 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
              UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
              Other crossreferences
              AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
              DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
              EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
              FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
              FlyMine - An integrated database for Drosophila genomics
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              MARRVEL_MODEL - MARRVEL (model organism gene)
              Linkouts
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              DroID - A comprehensive database of gene and protein interactions.
              DRSC - Results frm RNAi screens
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
              FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              Flygut - An atlas of the Drosophila adult midgut
              iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
              KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.
              KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
              MIST (genetic) - An integrated Molecular Interaction Database
              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
              References (87)