FlyBase Gene Report: Dmel\Pxd

General Information

Symbol

Dmel\Pxd

Species

D. melanogaster

Name

Peroxidase

Annotation Symbol

CG3477

Feature Type

protein_coding_gene

FlyBase ID

FBgn0004577

Gene Model Status

Current

Stock Availability

8 publicly available

Enzyme Name (EC)

peroxidase (1.11.1.7)

Gene Summary

Peroxidase (Pxd) encodes an enzyme that converts hydrogen peroxide to water and molecular oxygen, in the process oxidizing glutathione to glutathione disulfide. It is involved in the cellular response to oxidative stress. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Also Known As

DmPO

Key Links

Genomic Location

Cytogenetic map

89E8-89E9

Sequence location

3R:17,014,576..17,027,987 [+]

Recombination map

3-59

RefSeq locus

NT_033777 REGION:17014576..17027987

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (6 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables lactoperoxidase activity

inferred from direct assay

(Konstandi et al., 2005)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables heme binding

inferred from electronic annotation with InterPro:IPR010255

(InterPro Project Members, 2004-)

enables peroxidase activity

inferred from biological aspect of ancestor with PANTHER:PTN000158755

(GO Reference Genome Project, 2011-)

inferred from electronic annotation with InterPro:IPR010255

(InterPro Project Members, 2004-)

Biological Process (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in egg chorion assembly

inferred by curator from GO:0042600

(Konstandi et al., 2005)

involved_in response to oxidative stress

inferred from electronic annotation with InterPro:IPR010255

(InterPro Project Members, 2004-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in egg chorion

inferred from direct assay

(Konstandi et al., 2005)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

HEME PEROXIDASES

Protein Family (UniProt)

Belongs to the peroxidase family. XPO subfamily. (Q01603)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

lactoperoxidase activity

2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O (1.11.1.7)

RHEA 56136:

Summaries

Gene Snapshot

Gene Group (FlyBase)

HEME PEROXIDASES -: Heme peroxidases are heme enzymes found in bacteria, fungi, plants and animals, which exploit the reduction of hydrogen peroxide to catalyze a number of oxidative reactions, involving a wide variety of organic and inorganic substrates. (Adapted from PMID: 20211593.)

Protein Function (UniProtKB)

Involved in the chorion hardening process, through protein cross-linking mediated by the formation of di- and tri-tyrosine bonds.

(UniProt, Q01603)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Pxd for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q01603)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.48

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Pxd-RA

FBtr0089287

NM_206501

2558

690

Pxd-RB

FBtr0301526

NM_001170162

2231

690

Pxd-RC

FBtr0337061

NM_001275725

2552

688

Additional Transcript Data and Comments

Reported size (kB)

3.2 (northern blot)

(Ng et al., 1992)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Pxd-PA

FBpp0088343

76.7

690

6.28

FBpp0290741

76.7

690

6.28

FBpp0307990

76.5

688

6.28

A0A0B4KHM9

NP_001262654

AGB96034

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

690 aa isoforms: Pxd-PA, Pxd-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

690 (aa); 77 (kD predicted)

(Ng et al., 1992)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pxd using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Pxd_1
Pxd_2

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.30

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

oogenesis stage S11 -- S14

follicle cell

(Konstandi et al., 2005)

Additional Descriptive Data

Pxd is detected in follicle cells in stage 11 egg chanbers and levels substanitally increased during stages 12 and 13. At stage 12, activity is specifically enriched at the posterior pole and the respiratory filaments of the developing follicle.

(Konstandi et al., 2005)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

oogenesis stage S14

follicle cell

(Konstandi et al., 2005)

endochorion

(Konstandi et al., 2005)

micropyle

(Konstandi et al., 2005)

Additional Descriptive Data

Pxd is mainly detected in the respiratory filaments, in the micropyle area, and in the chorion structure of a stage 14 follicle

(Konstandi et al., 2005)

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in egg chorion

inferred from direct assay

(Konstandi et al., 2005)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Pxd in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Pxd

View exonic expression by tissue for Dmel\Pxd

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

2768671/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0004577

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0004577

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0004577

Flygut - An atlas of the Drosophila adult midgut

FBgn0004577

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 14 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Pxd

Transgenic constructs containing regulatory region of Pxd

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene partially disrupted in

Df(3R)CRIMIC-CR71346

(Gene Disruption Project members, 2018-)

Inferred from location ( 5 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^insc-Mz1407

Pxd^GD16228

partially lethal | chemical conditional

Pxd^EY15388

partially lethal - majority die, with Scer\GAL4^pnr-MD237

Pxd^GD16228

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Pxd^GD16228

viable, with Scer\GAL4^Mef2.PR

Pxd^GD16228

Other Phenotypes

Allele

abnormal neuroanatomy | larval stage, with Scer\GAL4^insc-Mz1407

Pxd^GD16228

chemical sensitive

Pxd^EY15388

some die during pupal stage, with Scer\GAL4^pnr-MD237

Pxd^GD16228

visible, with Scer\GAL4^pnr-MD237

Pxd^GD16228

visible | adult stage

Pxd^i1del

visible | adult stage, with Scer\GAL4^nub-AC-62

Pxd^GD16228

Phenotype manifest in

Allele

ganglion mother cell | larval stage, with Scer\GAL4^insc-Mz1407

Pxd^GD16228

larval neuroblast | larval stage, with Scer\GAL4^insc-Mz1407

Pxd^GD16228

mesonotum, with Scer\GAL4^pnr-MD237

Pxd^GD16228

trichogen cell, with Scer\GAL4^pnr-MD237

Pxd^GD16228

wing

Pxd^i1del

wing, with Scer\GAL4^nub-AC-62

Pxd^GD16228

wing vein | ectopic

Pxd^i1del

wing vein | ectopic, with Scer\GAL4^nub-AC-62

Pxd^GD16228

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (21)

Hsap\EPX

5 of 14

Yes

Hsap\LPO

5 of 14

Yes

Hsap\MPO

5 of 14

Yes

Hsap\PXDN

5 of 14

Yes

Hsap\PXDNL

5 of 14

Yes

Hsap\TPO

4 of 14

Yes

Hsap\PTGS1

2 of 14

Yes

Hsap\PTGS2

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (14)

Rnor\Epx

5 of 14

Yes

Rnor\Lpo

5 of 14

Yes

Rnor\Mpo

4 of 14

Rnor\Pxdn

4 of 14

Rnor\Tpo

4 of 14

Yes

Rnor\Ptgs1

2 of 14

Yes

Rnor\Ptgs2

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (18)

Mmus\Epx

5 of 14

Yes

Mmus\Mpo

5 of 14

Yes

Mmus\Pxdn

5 of 14

Yes

Mmus\Lpo

4 of 14

Mmus\Tpo

4 of 14

Yes

Mmus\Ptgs1

2 of 14

Yes

Mmus\Ptgs2

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (15)

Xtro\pxdn

3 of 13

Yes

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (17)

Drer\mpx

5 of 14

Yes

Drer\epx

4 of 14

Yes

Drer\pxdn

4 of 14

Drer\ptgs1

2 of 14

Yes

Drer\ptgs2a

2 of 14

Yes

Drer\ptgs2b

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Drer\si:ch211-159i8.4

1 of 14

Drer\tpo

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (15)

Cele\hpx-2

6 of 14

Yes

Cele\mlt-7

6 of 14

Yes

Cele\R08F11.7

6 of 14

Yes

5 of 14

5 of 14

5 of 14

5 of 14

4 of 14

4 of 14

4 of 14

4 of 14

1 of 14

1 of 14

1 of 14

Yes

Cele\sma-10

1 of 14

Anopheles gambiae (African malaria mosquito) (25)

Agam\HPX1

12 of 12

Yes

Agam\HPX10

6 of 12

Yes

Agam\HPX11

6 of 12

Yes

Agam\HPX14

6 of 12

Yes

Agam\HPX15

6 of 12

Yes

Agam\HPX5

5 of 12

Agam\HPX16

5 of 12

Yes

Agam\PERC_ANOGA

5 of 12

Agam\AgaP_AGAP004036

4 of 12

Agam\AgaP_AGAP010735

4 of 12

Yes

4 of 12

4 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (12)

Atha\ALPHA DOX2

5 of 13

Yes

Atha\DOX1

5 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Pxd. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (14)

CG4009

9 of 13

Pxt

8 of 13

cysu

7 of 13

Irc

7 of 13

Pxn

7 of 13

6 of 13

CG10211

5 of 13

CG42331

5 of 13

Duox

2 of 13

Lar

1 of 13

lbk

1 of 13

Nox

1 of 13

Obsc

1 of 13

sls

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 3 )

Human Ortholog

Disease

Evidence

References

MPO; myeloperoxidase

model of Alzheimer's disease 1

IEA

(FlyBase, 2019-)

PXDN; peroxidasin

model of anterior segment dysgenesis 7

IEA

(FlyBase, 2019-)

TPO; thyroid peroxidase

model of thyroid dyshormonogenesis 2A

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

EPX; eosinophil peroxidase

5 of 14

131399

EOSINOPHIL PEROXIDASE DEFICIENCY; EPXD

5 of 14

5 of 14

Alzheimer's disease 1

PXDN; peroxidasin

5 of 14

605158

ANTERIOR SEGMENT DYSGENESIS 7; ASGD7

anterior segment dysgenesis 7

PXDNL; peroxidasin like

5 of 14

615904

TPO; thyroid peroxidase

4 of 14

606765

THYROID DYSHORMONOGENESIS 2A; TDH2A

thyroid dyshormonogenesis 2A

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0004577

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

xanthommatin biosynthesis

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-59

Cytogenetic map

89E8-89E9

Sequence location

3R:17,014,576..17,027,987 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

89E8-89E9

Limits computationally determined from genome sequence between P{EP}MESK4^EP1015 and P{EP}CG5208^EP562&P{EP}Dad^EP3196

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

89E11-89E11

(determined by in situ hybridisation)

(Ranz et al., 2001)

89D-89E

(determined by in situ hybridisation)

(Ng et al., 1992)

Experimentally Determined Recombination Data

Location

3-59

(FlyBase, 2016)

3-59.0

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (8)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

63904

w¹¹¹⁸; PBac{IT.GAL4}Pxd^0928-G4

42098

y¹ w^*; Mi{MIC}Pxd^MI05654

53840

y¹ w^*; Mi{MIC}Pxd^MI10326

21129

y¹ w^67c23; P{EPgy2}Pxd^EY15388

33266

w¹¹¹⁸; P{EP}Pxd^G4163/TM6C, Sb¹

57507

y¹ sc^* v¹ sev²¹; P{TRiP.HMC04822}attP40

VDRC

v48587

w¹¹¹⁸; P{GD16228}v48587

v48588

w¹¹¹⁸; P{GD16228}v48588

Genomic Clones (16)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (7)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

IP20232

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0004577

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0004577

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.

(Stroschein-Stevenson et al., 2006)

Annotation CG3477 restored in release 3.2 of the genome annotation.

(FlyBase Genome Annotators, 2004)

Annotation CG3477 was eliminated in release 3 of the genome annotation, October 2002.

(FlyBase Genome Annotators, 2002-2003)

In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.

(Kliman and Eyre-Walker, 1998)

Pxd has been cloned and sequenced.

(Ng et al., 1992)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

CG3477

(Hosono et al., 2015, Ni et al., 2010.12.1, Lebo et al., 2009, Yandell et al., 2005)

DmPO

(Ng et al., 1992)

Dpxd

(Vazquez et al., 2002)

HPX1

(Hughes, 2012)

(Petersen, 1992.8.18)

Pxd

(Li et al., 2024, Salminen et al., 2024, Clandinin and Owens, 2016-, Duun Rohde et al., 2016, Hurd et al., 2015, Logan-Garbisch et al., 2014, Pezzulo et al., 2012, Heifetz and Rivlin, 2010, Clark and Herrmann, 2008, Stroschein-Stevenson et al., 2006, Konstandi et al., 2005)

pxd

(Nozawa et al., 2023)

Name Synonyms

Peroxidase

(Logan-Garbisch et al., 2014, Heifetz and Rivlin, 2010, Lebo et al., 2009)

peroxidase

(Konstandi et al., 2005)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 42 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

2768671

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q01603

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q01603

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q01603

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

2768671/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0004577

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0004577

FlyMine - An integrated database for Drosophila genomics

FBgn0004577

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG3477

MARRVEL_MODEL - MARRVEL (model organism gene)

2768671

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0004577

DroID - A comprehensive database of gene and protein interactions.

FBgn0004577

DRSC - Results frm RNAi screens

FBgn0004577

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Pxd_1
Pxd_2

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0004577

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0004577

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

xanthommatin biosynthesis

Flygut - An atlas of the Drosophila adult midgut

FBgn0004577

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC000175

References (59)

The following external sites may use different assemblies or annotations than FlyBase.

-0.30

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