FlyBase Gene Report: Dmel\pdgy

General Information

Symbol

Dmel\pdgy

Species

D. melanogaster

Name

pudgy

Annotation Symbol

CG9009

Feature Type

protein_coding_gene

FlyBase ID

FBgn0027601

Gene Model Status

Current

Stock Availability

11 publicly available

Enzyme Name (EC)

long-chain-fatty-acid--CoA ligase (6.2.1.3)

Gene Summary

pudgy (pdgy) encodes an acyl-CoA synthetase that activates fatty acids by conjugating them to CoA. It is a FOXO transcriptional target that preferentially activates fatty acids destined for beta-oxidation. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

BcDNA:GH02901

Key Links

Genomic Location

Cytogenetic map

13A1-13A1

Sequence location

X:14,933,670..14,953,532 [-]

Recombination map

1-49

RefSeq locus

NC_004354 REGION:14933670..14953532

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (5 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables long-chain fatty acid-CoA ligase activity

inferred from direct assay

(Xu et al., 2012)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables long-chain fatty acid-CoA ligase activity

inferred from biological aspect of ancestor with PANTHER:PTN004669355

(GO Reference Genome Project, 2011-)

Biological Process (3 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

involved_in fatty-acyl-CoA biosynthetic process

inferred from direct assay

(Xu et al., 2012)

involved_in long-chain fatty acid metabolic process

inferred from direct assay

(Xu et al., 2012)

involved_in triglyceride catabolic process

inferred from direct assay

(Xu et al., 2012)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in fatty-acyl-CoA biosynthetic process

inferred from biological aspect of ancestor with PANTHER:PTN004669355

(GO Reference Genome Project, 2011-)

involved_in long-chain fatty acid metabolic process

inferred from biological aspect of ancestor with PANTHER:PTN004669355

(GO Reference Genome Project, 2011-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in mitochondrion

inferred from direct assay

(Xu et al., 2012)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in mitochondrion

inferred from biological aspect of ancestor with PANTHER:PTN002787847

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

FATTY ACYL-COA SYNTHETASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

long-chain fatty acid-CoA ligase activity

a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate (6.2.1.3)

RHEA 15421:

Summaries

Gene Snapshot

Gene Group (FlyBase)

FATTY ACYL-COA SYNTHETASES -: Fatty acyl-coenzyme A (CoA) synthetases catalyze the "activation" of fatty acids by their thioesterification to CoA. This is the initial reaction in fatty acid metabolism, allowing their participation in many fundamental anabolic and catabolic pathways. (Adapted from FBrf0237395.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\pdgy for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VXZ8)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.52

Gene model reviewed during 5.40

Gene model reviewed during 5.55

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

pdgy-RA

FBtr0073972

NM_132760

2534

597

pdgy-RB

FBtr0303294

NM_001201661

3407

597

pdgy-RC

FBtr0308838

NM_001258744

2980

597

pdgy-RD

FBtr0343521

NM_001298328

2780

597

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

pdgy-PA

FBpp0073789

65.6

597

7.29

FBpp0292386

65.6

597

7.29

FBpp0300995

65.6

597

7.29

FBpp0310125

65.6

597

7.29

Q9VXZ8

NP_001285257

AHN59727

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

597 aa isoforms: pdgy-PA, pdgy-PB, pdgy-PC, pdgy-PD

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VXZ8

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\pdgy using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.80

Transcript Expression

expression microarray

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult fat body

Comment: cyclical, peak CT21-0

(Xu et al., 2011)

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

anlage in statu nascendi

(Fisher et al., 2012)

hindgut anlage in statu nascendi

(Fisher et al., 2012)

organism | gap expression pattern

(Fisher et al., 2012)

embryonic stage 7 -- 8

anterior endoderm anlage

(Fisher et al., 2012)

hindgut anlage

(Fisher et al., 2012)

organism | pair rule expression pattern

(Fisher et al., 2012)

posterior endoderm

(Fisher et al., 2012)

trunk mesoderm

(Fisher et al., 2012)

ventral ectoderm

(Fisher et al., 2012)

embryonic stage 9 -- 10

anterior endoderm

(Fisher et al., 2012)

inclusive hindgut primordium

(Fisher et al., 2012)

posterior endoderm

(Fisher et al., 2012)

embryonic stage 11 -- 12

anterior midgut primordium

(Fisher et al., 2012)

dorsal epidermis primordium

(Fisher et al., 2012)

foregut primordium

(Fisher et al., 2012)

hindgut proper primordium

(Fisher et al., 2012)

Malpighian tubule primordium

(Fisher et al., 2012)

posterior midgut primordium

(Fisher et al., 2012)

somatic muscle primordium

Comment: reported as muscle system primordium

(Fisher et al., 2012)

trunk visceral muscle primordium

Comment: reported as muscle system primordium

(Fisher et al., 2012)

ventral epidermis primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic dorsal epidermis

(Fisher et al., 2012)

embryonic epipharynx

(Fisher et al., 2012)

embryonic foregut

(Fisher et al., 2012)

embryonic hindgut

(Fisher et al., 2012)

embryonic hypopharynx

(Fisher et al., 2012)

embryonic Malpighian tubule

(Fisher et al., 2012)

embryonic ventral epidermis

(Fisher et al., 2012)

embryonic/larval midgut

(Fisher et al., 2012)

RT-PCR

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

embryonic/larval fat body

Comment: upregulated upon 18 hours of fasting

(Xu et al., 2012)

larval muscle system

Comment: upregulated upon 18 hours of fasting

(Xu et al., 2012)

Additional Descriptive Data

Expressed cyclically in the adult fat body.

(Xu et al., 2011)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in mitochondrion

inferred from direct assay

(Xu et al., 2012)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\pdgy in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\pdgy

View exonic expression by tissue for Dmel\pdgy

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0027601

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

32426/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0027601

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0027601

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0027601

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG9009

Flygut - An atlas of the Drosophila adult midgut

FBgn0027601

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\pdgy

Stages(s) 1-3
Stages(s) 4-6
Stages(s) 7-8
Stages(s) 9-10
Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 9 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of pdgy

Transgenic constructs containing regulatory region of pdgy

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 11 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

pdgy^GD4677

viable, with Scer\GAL4^Mef2.PR

pdgy^GD4677

viable, with Scer\GAL4^pnr-MD237

pdgy^GD4677

viable, with Scer\GAL4^tin.CΔ4

pdgy^GD4677

Sterility

Allele

fertile

Other Phenotypes

Allele

decreased body size

pdgy^BG02662

long lived

pdgy^BG02662

long lived | nutrition conditional

pdgy^BG02662

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (29)

Hsap\ACSF2

4 of 14

Yes

Hsap\ACSF3

2 of 14

Hsap\ACSL3

2 of 14

Hsap\ACSM1

2 of 14

Yes

Hsap\ACSM2A

2 of 14

Yes

Hsap\ACSM2B

2 of 14

Yes

Hsap\ACSM3

2 of 14

Yes

Hsap\ACSM4

2 of 14

Yes

Hsap\ACSM5

2 of 14

Yes

Hsap\ACSM6

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (22)

Rnor\Acsf2

4 of 14

Yes

Rnor\Acsf3

2 of 14

Rnor\Acsm3

2 of 14

Yes

Rnor\Acsm4

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Acsm2

1 of 14

Rnor\Acsm5

1 of 14

Yes

Rnor\Acss3

1 of 14

Rnor\Dip2c

1 of 14

Rnor\LOC316124

1 of 14

Mus musculus (laboratory mouse) (21)

Mmus\Acsf2

4 of 14

Yes

Mmus\Acsf3

2 of 14

Mmus\Acsm2

2 of 14

Yes

Mmus\Acsm3

2 of 14

Yes

Mmus\Acsm4

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (11)

Xtro\acsm3

2 of 13

Yes

Xtro\aacs

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (28)

Drer\acsf2

4 of 14

Yes

Drer\acsm3

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (22)

Cele\acs-14

9 of 14

Yes

6 of 14

6 of 14

6 of 14

6 of 14

5 of 14

4 of 14

4 of 14

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (22)

Agam\AgaP_AGAP002718

11 of 12

Yes

6 of 12

6 of 12

6 of 12

5 of 12

Yes

5 of 12

3 of 12

3 of 12

3 of 12

Yes

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (35)

Atha\4CL1

12 of 13

Yes

Atha\4CL2

12 of 13

Yes

Atha\4CL5

10 of 13

Yes

Atha\ACOS5

10 of 13

Atha\AT4G05160

10 of 13

Atha\AT4G19010

10 of 13

Yes

9 of 13

9 of 13

9 of 13

9 of 13

9 of 13

8 of 13

8 of 13

3 of 13

3 of 13

3 of 13

Yes

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (7)

Scer\PCS60

6 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (3)

Spom\SPCC1827.03c

5 of 12

Yes

Spom\mug62

1 of 12

Spom\SPAC56F8.02

1 of 12

Escherichia coli (enterobacterium) (7)

Ecol\fadD

7 of 11

Yes

Ecol\caiC

5 of 11

Yes

Ecol\fadK

3 of 11

Ecol\menE

3 of 11

Yes

Ecol\aas

1 of 11

Ecol\entE

1 of 11

Yes

Ecol\prpE

1 of 11

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:pdgy. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (27)

10 of 13

5 of 13

5 of 13

5 of 13

5 of 13

5 of 13

5 of 13

5 of 13

5 of 13

5 of 13

5 of 13

5 of 13

5 of 13

3 of 13

3 of 13

bgm

2 of 13

Fatp1

2 of 13

Fatp2

2 of 13

Fatp3

2 of 13

hll

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

ACSF2; acyl-CoA synthetase family member 2

4 of 14

610465

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0027601

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-49

Cytogenetic map

13A1-13A1

Sequence location

X:14,933,670..14,953,532 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

13A1-13A1

Limits computationally determined from genome sequence between P{EP}EP334&P{EP}EP977 and P{EP}hiw^EP1305

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

1-49

(FlyBase, 2016)

1-49.5

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (11)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

38050

y¹ w^* Mi{MIC}pdgy^MI04730

19990

y¹ w^67c23 P{EPgy2}pdgy^EY02124

60218

y¹ w^* Mi{PT-GFSTF.0}pdgy^{MI04730-GFSTF.0}

55272

y¹ sc^* v¹ sev²¹; P{TRiP.HMC03959}attP40

41453

y¹ w^* Mi{MIC}lncRNA:CR44831^MI06635 pdgy^MI06635

56949

y¹ sc^* v¹ sev²¹; P{TRiP.HMC04389}attP2/TM3, Sb¹

10810

11286

11429

v100411

v12016

w¹¹¹⁸; P{GD4677}v12016

Genomic Clones (21)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (84)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

GH02901

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0027601

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0027601

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Transcriptionally downregulated after 2h of insulin stimulation in Kc167 cells. Contains fkh response elements (FHREs) in the genomic upstream or intronic sequences.

(Junger et al., 2003)

Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days.

(Claridge-Chang et al., 2001)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: BcDNA:GH02901 CG9009

(Wang, 1999.11)

Source for identity of: pdgy CG9009

(Xu et al., 2012)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

Name Synonyms

Pudgy

(Heier et al., 2021, Toprak et al., 2020)

long chain fatty acid CoA ligase

(Gronke et al., 2005)

pudgy

(Shafer, 2025, Clerbaux et al., 2021, Thimgan et al., 2018)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 56 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

32426

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VXZ8

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9VXZ8

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VXZ8

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0027601

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

32426/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0027601

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0027601

FlyMine - An integrated database for Drosophila genomics

FBgn0027601

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG9009

MARRVEL_MODEL - MARRVEL (model organism gene)

32426

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0027601

DroID - A comprehensive database of gene and protein interactions.

FBgn0027601

DRSC - Results frm RNAi screens

FBgn0027601

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0027601

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0027601

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG9009

Flygut - An atlas of the Drosophila adult midgut

FBgn0027601

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

References (64)

The following external sites may use different assemblies or annotations than FlyBase.

-0.80

Report Sections