FlyBase Gene Report: Dmel\CG34384

General Information

Symbol

Dmel\CG34384

Species

D. melanogaster

Name

Annotation Symbol

CG34384

Feature Type

protein_coding_gene

FlyBase ID

FBgn0085413

Gene Model Status

Current

Stock Availability

11 publicly available

Enzyme Name (EC)

diacylglycerol kinase (ATP) (2.7.1.107)

Gene Summary

Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). (UniProt, A8JQ65)

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

84E1-84E3

Sequence location

3R:7,814,361..7,855,392 [+]

Recombination map

3-48

RefSeq locus

NT_033777 REGION:7814361..7855392

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (8 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables ATP-dependent diacylglycerol kinase activity

inferred from sequence or structural similarity with UniProtKB:Q86XP1

(Gene Ontology Curators, 2002-)

inferred from electronic annotation with InterPro:IPR000756, InterPro:IPR037607

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN007499105

(GO Reference Genome Project, 2011-)

enables kinase activity

inferred from electronic annotation with InterPro:IPR001206

(InterPro Project Members, 2004-)

Biological Process (5 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (5 terms)

CV Term

Evidence

References

involved_in diacylglycerol metabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000135281

(GO Reference Genome Project, 2011-)

involved_in intracellular signal transduction

inferred from biological aspect of ancestor with PANTHER:PTN007499105

(GO Reference Genome Project, 2011-)

involved_in phosphatidic acid biosynthetic process

inferred from biological aspect of ancestor with PANTHER:PTN000135281

(GO Reference Genome Project, 2011-)

involved_in phospholipase C-activating G protein-coupled receptor signaling pathway

inferred from electronic annotation with InterPro:IPR000756

(InterPro Project Members, 2004-)

involved_in signal transduction

inferred from electronic annotation with InterPro:IPR037607

(InterPro Project Members, 2004-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN000883263

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

DIACYLGLYCEROL KINASES

Protein Family (UniProt)

Belongs to the eukaryotic diacylglycerol kinase family. (A8JQ65)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

ATP-dependent diacylglycerol kinase activity

a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+) (2.7.1.107)

RHEA 10272:

Summaries

Gene Group (FlyBase)

DIACYLGLYCEROL KINASES -: Diacylglycerol kinases catalyze the phosphorylation of diacylglycerol to form phosphatidic acid. (Adapted from FBrf0161471).

Protein Function (UniProtKB)

Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).

(UniProt, A8JQ65)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\CG34384 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry A8JQ65)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.53

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

CG34384-RA

FBtr0112625

NM_001104234

7200

1895

CG34384-RB

FBtr0302036

NM_169197

6162

1733

CG34384-RC

FBtr0304918

NM_001260040

8761

1918

CG34384-RD

FBtr0304919

NM_001260041

7128

1871

CG34384-RE

FBtr0304920

NM_001260042

7323

1936

CG34384-RF

FBtr0344342

NM_001300284

7197

1894

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

CG34384-PA

FBpp0111537

211.7

1895

6.82

FBpp0291246

193.0

1733

6.59

FBpp0293457

214.3

1918

7.04

FBpp0293458

208.8

1871

6.86

FBpp0293459

216.3

1936

7.08

FBpp0310723

211.5

1894

6.82

A0A0B4LHW4

NP_001287213

AHN57212

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CG34384 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.16

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\CG34384 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\CG34384

View exonic expression by tissue for Dmel\CG34384

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

5740362/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0085413

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0085413

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0085413

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG31187

Flygut - An atlas of the Drosophila adult midgut

FBgn0085413

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 10 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 7 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of CG34384

Transgenic constructs containing regulatory region of CG34384

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 11 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal

CG34384^{MI01574-GFSTF.0}

viable

CG34384^f01626

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

viable, with Scer\GAL4^Mef2.PR

viable, with Scer\GAL4^pnr-MD237

viable, with Scer\GAL4^tin.CΔ4

CG34384^GD10189

Sterility

Allele

fertile

CG34384^f01626

Other Phenotypes

Allele

abnormal flight, with Scer\GAL4^Mef2.PR

CG34384^GD15750

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (58)

Hsap\DGKH

13 of 14

Yes

Hsap\DGKD

12 of 14

Yes

Hsap\DGKK

8 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\PLEKHA2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\STAP2

1 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (35)

Rnor\Dgkh

12 of 14

Yes

Rnor\Dgkd

11 of 14

Yes

Rnor\Dgkk

7 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Plekha2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mus musculus (laboratory mouse) (39)

Mmus\Dgkd

12 of 14

Yes

Mmus\Dgkh

12 of 14

Yes

Mmus\Dgkk

7 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Plekha2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Xenopus tropicalis (Western clawed frog) (33)

Xtro\dgkk

9 of 13

Yes

Xtro\dgkh

8 of 13

Yes

Xtro\dgkd

6 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\klhl17

1 of 13

Xtro\LOC100488567

1 of 13

Xtro\LOC100498645

1 of 13

Yes

Xtro\mir96

1 of 13

Yes

Xtro\plekha1

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\stap2

1 of 13

Yes

Xtro\tmbim1

1 of 13

Xtro\unc13c

1 of 13

Danio rerio (Zebrafish) (39)

Drer\si:dkey-172j4.3

12 of 14

Yes

Drer\dgkh

11 of 14

Yes

Drer\LOC100334707

5 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\plekha1a

1 of 14

Yes

Drer\plekha1b

1 of 14

Yes

Drer\plekha2

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\stap2b

1 of 14

Yes

Drer\zak

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (23)

Cele\dgk-4

12 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Cele\rig-4

1 of 14

Cele\rsf-1

1 of 14

Yes

Cele\shn-1

1 of 14

Cele\tpa-1

1 of 14

Cele\unc-13

1 of 14

Anopheles gambiae (African malaria mosquito) (19)

Agam\AgaP_AGAP002226

12 of 12

Yes

2 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (8)

Atha\DGK1

2 of 13

Yes

Atha\DGK2

2 of 13

Yes

Atha\DGK3

2 of 13

Yes

Atha\DGK4

2 of 13

Yes

Atha\DGK5

2 of 13

Yes

Atha\DGK6

2 of 13

Yes

Atha\DGK7

2 of 13

Yes

Atha\LCBK2

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\pob1

1 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:CG34384. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (21)

CG31140

4 of 13

Dgk

4 of 13

Dgkε

4 of 13

rdgA

4 of 13

aPKC

1 of 13

ave

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

ckn

1 of 13

gek

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

PKD

1 of 13

SKIP

1 of 13

unc-13

1 of 13

Vav

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

DGKH; diacylglycerol kinase eta

13 of 14

604071

DGKD; diacylglycerol kinase delta

12 of 14

601826

DGKK; diacylglycerol kinase kappa

8 of 14

300837

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

624993

DroID - A comprehensive database of gene and protein interactions.

FBgn0085413

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Effects of PIP2 hydrolysis

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-48

Cytogenetic map

84E1-84E3

Sequence location

3R:7,814,361..7,855,392 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

84E1-84E3

Limits computationally determined from genome sequence between P{EP}EP3060^EP3060 and P{PZ}grn⁰⁵⁹³⁰

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-48

(FlyBase, 2016)

3-44.5

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (11)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

18453

w¹¹¹⁸; PBac{WH}CG34384^f01626

59090

y¹ w^*; Mi{MIC}CG34384^MI12624

22741

y¹ w^67c23; Mi{ET1}CG34384^MB00245

82489

y¹ sc^* v¹ sev²¹; P{WKO.1-B9}attP40

13425

y¹ w^67c23; P{SUPor-P}CG34384^KG01333 ry⁵⁰⁶

35103

y¹ w^*; Mi{MIC}CG34384^MI01574/TM3, Sb¹ Ser¹

63160

y¹ w^*; Mi{PT-GFSTF.0}CG34384^{MI01574-GFSTF.0}/TM6C, Sb¹ Tb¹

606534

y¹ w^*; TI{CRIMIC.TG4.0}CG34384^{CR71142-TG4.0}/TM3, Sb¹ Ser¹

31187R-1

v102481

v43739

w¹¹¹⁸; P{GD10189}v43739

Genomic Clones (30)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (9)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0085413

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0085413

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R⁺ cell morphology.

(Kiger et al., 2003)

RNAi experiments show that dsRNA targetted at this gene suppresses the Pten-dsRNA-induced cell shape changes in Kc167 cells.

(Kiger et al., 2003)

Relationship to Other Genes

Source for database merge of

Source for merge of: CG14462 CG31187

(FlyBase Genome Annotators, 2007)

Source for merge of: CG2667 CG9851

(FlyBase Genome Annotators, 2002-2003)

Additional comments

Annotations CG14462 and CG31187 merged as CG34384 in release 5.2 of the genome annotation.

(FlyBase Genome Annotators, 2007)

Annotations CG2667 and CG9851 merged as CG31187 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

CG14462

CG2667

CG31187

(Cockcroft and Raghu, 2016, Matthews, 2008.4.15, Maines et al., 2007)

CG34384

(Corthals et al., 2023, Praschberger et al., 2023, Meltzer et al., 2019, Gene Disruption Project members, 2018-, Gene Disruption Project members, 2015-, Yin et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Friedman et al., 2011, Keleman et al., 2009.8.5, FlyBase Genome Annotators, 2007)

CG9851

DGKd

(Morrison et al., 2000)

DgkD

(Martin et al., 2013)

dgk

(Medina-Yáñez et al., 2020)

dgkd

(Mattila et al., 2008)

Name Synonyms

CG14462

CG31187

Secondary FlyBase IDs

FBgn0037524
FBgn0037523
FBgn0040523
FBgn0051187

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 70 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

5740362

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

A8JQ65

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

A8JQ65

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

A8JQ65

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

5740362/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0085413

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0085413

FlyMine - An integrated database for Drosophila genomics

FBgn0085413

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG34384

MARRVEL_MODEL - MARRVEL (model organism gene)

5740362

Linkouts

BioGRID - A database of protein and genetic interactions.

624993

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0085413

DroID - A comprehensive database of gene and protein interactions.

FBgn0085413

DRSC - Results frm RNAi screens

FBgn0085413

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0085413

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0085413

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG31187

Flygut - An atlas of the Drosophila adult midgut

FBgn0085413

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0085413

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC013915

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Effects of PIP2 hydrolysis

References (56)

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