PKC, dPKC98F, PKC 98F, protein kinase C, Pkc3
serine/threonine kinase, diacylglycerol binding protein - flies expressing a PKC pseudosubstrate show an alteration in performance in courtship conditioning; they fail to show immediate suppression of courtship, a trait exhibited by normal flies IKK inhibits PKC to promote Fascin-dependent actin bundling
Please see the JBrowse view of Dmel\Pkc98E for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.49
Multiphase exon postulated: reading frame of first coding exon differs in alternative transcripts; overlap >20aa.
5.5, 4.5, 4.3 (northern blot)
634 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pkc98E using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\Pkc98E in JBrowse3-97
3-94.6
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
The protein kinase C (PKC) enzyme in Drosophila is encoded by a gene family made up of three genes which are expressed primarily in adult flies. The deduced amino acid sequences of these genes are quite similar to each other and those of the mammalian PKC family (Schaeffer, Smith, Mardon, Quinn and Zuker, 1989). Ca++-dependent
An evolutionarily conserved sequence from 98F expressed in neural tissue; Assigned to Pkc98E on basis of in situ determined map position. Structural gene for protein kinase C (PKC); expressed primarily in adult flies.
Source for identity of: Pkc98E CG1954
