FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\Snap29
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General Information
Symbol
Dmel\Snap29
Species
D. melanogaster
Name
Synaptosomal-associated protein 29kDa
Annotation Symbol
CG11173
Feature Type
protein_coding_gene
FlyBase ID
FBgn0290324
Gene Model Status
Current
Stock Availability
17 publicly available
Gene Summary
Synaptosomal-associated protein 29kDa (Snap29) encodes a member of the SNARE (soluble N-ethylmaleimide-sensitive factor-attachment protein (SNAP) receptor) family. It is involved in regulation of autophagy, endocytic recycling, cell division, and adult eye pigmentation. [Date last reviewed: 2018-10-18] (FlyBase Gene Snapshot)
All Summaries
Also Known As

usnp, ubisnap, pd, SNAP-29, purpleoid

Key Links
Genomic Location
Cytogenetic map
60A3-60A3
Sequence location
Recombination map
2-105
RefSeq locus
NT_033778 REGION:23843483..23844763
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (15 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
enables SNAP receptor activity
inferred from physical interaction with FLYBASE:Syx17; FB:FBgn0035540,FLYBASE:Vamp7; FB:FBgn0266186
(Takáts et al., 2013)
enables SNARE binding
inferred from physical interaction with FLYBASE:Syx17; FB:FBgn0035540,FLYBASE:Vamp7; FB:FBgn0266186
(Takáts et al., 2013)
inferred from physical interaction with FLYBASE:Syb; FB:FBgn0003660
(Morelli et al., 2014)
inferred from physical interaction with FLYBASE:Syx1A; FB:FBgn0013343
(Morelli et al., 2014)
inferred from physical interaction with FLYBASE:Syx4; FB:FBgn0024980
(Morelli et al., 2014)
inferred from physical interaction with FLYBASE:Sec22; FB:FBgn0260855
(Morelli et al., 2014)
inferred from physical interaction with FLYBASE:Vamp7; FB:FBgn0266186
(Morelli et al., 2014)
inferred from physical interaction with FLYBASE:Syx7; FB:FBgn0267849
(Morelli et al., 2014)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables SNAP receptor activity
inferred from biological aspect of ancestor with PANTHER:PTN000447753
(GO Reference Genome Project, 2011-)
enables syntaxin binding
inferred from biological aspect of ancestor with PANTHER:PTN000447753
(GO Reference Genome Project, 2011-)
Biological Process (10 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
involved_in autophagosome maturation
inferred from mutant phenotype
(Morelli et al., 2014, Takáts et al., 2013)
involved_in Golgi organization
inferred from mutant phenotype
(Morelli et al., 2014)
involved_in negative regulation of secretion by cell
inferred from mutant phenotype
(Morelli et al., 2014)
involved_in regulation of endocytosis
inferred from mutant phenotype
(Morelli et al., 2014)
involved_in secretory granule-lysosome fusion
inferred from mutant phenotype
(Csizmadia et al., 2018)
involved_in T-tubule organization
inferred from mutant phenotype
(Fujita et al., 2017)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
involved_in exocytosis
inferred from biological aspect of ancestor with PANTHER:PTN000447753
(GO Reference Genome Project, 2011-)
involved_in synaptic vesicle fusion to presynaptic active zone membrane
inferred from biological aspect of ancestor with PANTHER:PTN000447754
(GO Reference Genome Project, 2011-)
involved_in synaptic vesicle priming
inferred from biological aspect of ancestor with PANTHER:PTN000447754
(GO Reference Genome Project, 2011-)
involved_in vesicle-mediated transport
inferred from sequence or structural similarity
(Littleton, 2000)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
part_of SNARE complex
inferred from physical interaction with FLYBASE:Syx13; FB:FBgn0036341,FLYBASE:Vamp7; FB:FBgn0266186
(Csizmadia et al., 2018)
inferred from direct assay
(Takáts et al., 2013)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
is_active_in plasma membrane
inferred from biological aspect of ancestor with PANTHER:PTN000447752
(GO Reference Genome Project, 2011-)
part_of SNARE complex
inferred from biological aspect of ancestor with PANTHER:PTN000447753
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
Synaptosomal-associated protein 29kDa (Snap29) encodes a member of the SNARE (soluble N-ethylmaleimide-sensitive factor-attachment protein (SNAP) receptor) family. It is involved in regulation of autophagy, endocytic recycling, cell division, and adult eye pigmentation. [Date last reviewed: 2018-10-18]
Gene Group (FlyBase)
Qbc-SNAREs -
Q-SNAREs are members of the SNARE (soluble N-ethylmaleimide-sensitive factor-attachment protein (SNAP) receptor) family that mediate vesicle-fusion. SNAREs are cytoplasmic, membrane-anchored proteins that contain a 60 amino acid SNARE domain. Three Q-SNAREs domains from the target membrane and one R-SNARE domain from the vesicle interact to form a four four-helix bundle that pulls the two membranes in close proximity and promotes fusion. After fusion, the complexes are dissembled by NSF (N-ethylmaleimide-sensitive factor) and SNAPs (Soluble NSF Attachment Proteins). Q-SNAREs are named from their contribution of a conserved glutamine (Q) residue to the helix bundle. Q-SNARE domains are designated a, b or c, depending on their position within the helix bundle. Qbc-SNAREs (or SNAPs (synaptosomal-associated proteins) possess a Qb and Qc domain, thus contribute two helices to the bundle. (Adapted from PMID:15893389 and FBrf0216182).
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
pd: purpleoid
Eye color dark pink or maroon, like pr but less extreme. Semidominant; eye color of heterozygote duller than wild type; color autonomous in larval optic disk transplanted into wild-type host (Beadle and Ephrussi, 1936, Genetics 21: 230). Malpighian tubes wild type (Beadle, 1937, Genetics 22: 587-611). Semilethal with dor (Lucchesi, 1968, Genetics 59: 37-54). RK2.
Summary (Interactive Fly)

during mitosis - Snap29 mutant imaginal discs exhibit impairment of a late step of autophagy

Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Snap29 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9W1I8)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.52

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Snap29-RA
FBtr0072236
NM_079107
1212
284
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Snap29-PA
FBpp0072145
31.6
284
4.80
Q9W1I8
NP_523831
AAF47071
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Snap29 using the Feature Mapper tool.

External Data
Crossreferences
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

1.83

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 11 -- 12
garland cell primordium
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 13 -- 16
embryonic/larval garland cell
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
RT-PCR
Stage
Tissue/Position (including subcellular localization)
Reference
larval stage
eye disc
(Morelli et al., 2014)
wing disc
(Morelli et al., 2014)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
larval stage
wing disc
(Morelli et al., 2014)
eye disc
(Morelli et al., 2014)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
part_of SNARE complex
inferred from physical interaction with FLYBASE:Syx13; FB:FBgn0036341,FLYBASE:Vamp7; FB:FBgn0266186
(Csizmadia et al., 2018)
inferred from direct assay
(Takáts et al., 2013)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Snap29 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 3 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 20 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Snap29
Transgenic constructs containing regulatory region of Snap29
Aberrations (Deficiencies and Duplications) ( 21 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (3)
Hsap\SNAP29
14 of 14
Yes
Yes
Hsap\SNAP23
3 of 14
No
No
Hsap\SNAP25
2 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (4)
Rnor\Snap29
14 of 14
Yes
Yes
Rnor\Snap23
2 of 14
No
No
Rnor\Snap25
1 of 14
No
No
Rnor\Snap47
1 of 14
No
Yes
Mus musculus (laboratory mouse) (4)
Mmus\Snap29
14 of 14
Yes
Yes
Mmus\Snap23
2 of 14
No
No
Mmus\Snap25
2 of 14
No
No
Mmus\Snap47
1 of 14
No
Yes
Xenopus tropicalis (Western clawed frog) (4)
Xtro\snap29
11 of 13
Yes
Yes
Xtro\larp1
1 of 13
No
No
Xtro\snap23
1 of 13
No
No
Xtro\ube3b
1 of 13
No
No
Danio rerio (Zebrafish) (6)
Drer\snap29
13 of 14
Yes
Yes
Drer\snap23.1
3 of 14
No
No
Drer\snap23.2
3 of 14
No
No
Drer\snap25a
2 of 14
No
No
Drer\snap25b
2 of 14
No
No
Drer\zgc:101731
2 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (3)
Cele\snap-29
12 of 14
Yes
Yes
Cele\aex-4
2 of 14
No
No
Cele\ric-4
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (2)
Agam\AgaP_AGAP011135
11 of 12
Yes
Yes
Agam\AgaP_AGAP001394
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (3)
Atha\SNAP29
4 of 13
Yes
No
Atha\SNAP30
4 of 13
Yes
No
Atha\SNAP33
4 of 13
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (2)
Scer\SEC9
3 of 13
Yes
No
Scer\SPO20
2 of 13
No
No
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\sec9
3 of 12
Yes
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Snap29. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (2)
Snap24
4 of 13
Snap25
4 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Allele
Disease
Evidence
References
Snap29B6-21
model of  CEDNIK syndrome
CEA
(Morelli et al., 2014)
Potential Models Based on Orthology ( 1 )
Human Ortholog
Disease
Evidence
References
SNAP29; synaptosome associated protein 29
model of  CEDNIK syndrome
IEA
(FlyBase, 2019-)
Modifiers Based on Experimental Evidence ( 2 )
Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
SNAP29; synaptosome associated protein 29
14 of 14
604202
SNAP23; synaptosome associated protein 23
3 of 14
602534
      Functional Complementation Data
      Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
      Interactions
      Summary of Physical Interactions
      Interaction Browsers
      View in FlyBase Interactions Browser   View in MIST tool (external link)
      Please see the Physical Interaction reports below for full details
      protein-protein
      Physical Interaction
      Assay
      References
      Snap29 - AttD
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Bet1
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Cenp-C
      anti tag coimmunoprecipitation, peptide massfingerprinting
      (Przewloka et al., 2011)
      Snap29 - Dap160
      pull down, western blot
      (Xu et al., 2014)
      Snap29 - Gos28
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Membrin
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Ndc80
      anti tag coimmunoprecipitation, anti tag western blot
      (Morelli et al., 2016)
      Snap29 - Nsf2
      experimental knowledge based, anti bait coimmunoprecipitation, peptide massfingerprinting
      (Morelli et al., 2014, Guruharsha et al., 2011)
      Snap29 - Past1
      experimental knowledge based, pull down, western blot
      (Xu et al., 2014, Guruharsha et al., 2011)
      Snap29 - Rme-8
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Sec20
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Sec22
      experimental knowledge based, anti bait coimmunoprecipitation, peptide massfingerprinting
      (Morelli et al., 2014, Guruharsha et al., 2011)
      Snap29 - Slh
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Snap24
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Snap25
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Syb
      experimental knowledge based, anti bait coimmunoprecipitation, peptide massfingerprinting
      (Morelli et al., 2014, Guruharsha et al., 2011)
      Snap29 - Syx13
      anti tag coimmunoprecipitation, western blot, anti tag western blot, pull down, molecular weight estimation by staining, experimental knowledge based
      (Szenci et al., 2024, Csizmadia et al., 2018, Guruharsha et al., 2011)
      Snap29 - Syx16
      pull down, western blot, experimental knowledge based, anti bait coimmunoprecipitation
      (Xu et al., 2014, Guruharsha et al., 2011)
      Snap29 - Syx17
      anti bait coimmunoprecipitation, western blot, pull down, molecular weight estimation by staining, anti tag coimmunoprecipitation, anti tag western blot, experimental knowledge based
      (Xu et al., 2022, Takáts et al., 2018, Takáts et al., 2014, Takáts et al., 2013, Guruharsha et al., 2011)
      Snap29 - Syx18
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Syx1A
      experimental knowledge based, anti bait coimmunoprecipitation, western blot, peptide massfingerprinting, pull down
      (Morelli et al., 2014, Xu et al., 2014, Guruharsha et al., 2011)
      Snap29 - Syx4
      anti bait coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
      (Morelli et al., 2014, Guruharsha et al., 2011)
      Snap29 - Syx5
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Syx7
      experimental knowledge based, anti bait coimmunoprecipitation, peptide massfingerprinting
      (Morelli et al., 2014, Guruharsha et al., 2011)
      Snap29 - Syx8
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Use1
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Vamp7
      anti tag coimmunoprecipitation, anti tag western blot, anti bait coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
      (Xu et al., 2022, Morelli et al., 2014, Guruharsha et al., 2011)
      Snap29 - Vti1a
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - Ykt6
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - koko
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - nSyb
      experimental knowledge based
      (Guruharsha et al., 2011)
      Snap29 - αSnap
      pull down, western blot, anti bait coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
      (Morelli et al., 2014, Xu et al., 2014, Guruharsha et al., 2011)
      Snap29 - γSnap1
      experimental knowledge based, anti bait coimmunoprecipitation, peptide massfingerprinting
      (Morelli et al., 2014, Guruharsha et al., 2011)
      Snap29 - γSnap2
      experimental knowledge based
      (Guruharsha et al., 2011)
      Summary of Genetic Interactions
      Interaction Browsers
      View in FlyBase Interactions Browser   View in MIST tool (external link)
      Please look at the allele data for full details of the genetic interactions
      Starting gene(s)
      Interaction type
      Interacting gene(s)
      Reference
      Snap29
      enhanceable
      Sec22
      (Morelli et al., 2014)
      Snap29
      suppressible
      Socs36E
      (Morelli et al., 2014)
      Snap29
      enhanceable
      Syx17
      (Morelli et al., 2014)
      Snap29
      enhanceable
      Vamp7
      (Morelli et al., 2014)
      Starting gene(s)
      Interaction type
      Interacting gene(s)
      Reference
      External Data
      Linkouts
      Pathways
      Signaling Pathways (FlyBase)
      Metabolic Pathways
      FlyBase
      External Links
      External Data
      Linkouts
      Class of Gene
      Genomic Location and Detailed Mapping Data
      Chromosome (arm)
      2R
      Recombination map
      2-105
      Cytogenetic map
      60A3-60A3
      Sequence location
      FlyBase Computed Cytological Location
      Cytogenetic map
      Evidence for location
      60A3-60A3
      Limits computationally determined from genome sequence between P{EP}eglEP938 and P{lacW}eIF6k13214
      Experimentally Determined Cytological Location
      Cytogenetic map
      Notes
      References
      The pd complementation group maps to the genomic interval 2R:23811400..23844351 , release 6 genome (left limit from complementation mapping against Df(2R)BSC659, right limit from complementation mapping against Df(2R)BSC665).
      (Kahsai and Cook, 2018)
      60A3-60A4
      (Boulianne, 2000.6.6)
      Experimentally Determined Recombination Data
      Location

      2-105

      (FlyBase, 2016)

      2-109.6

      (Comeron et al., 2012)

      2-106.4

      Left of (cM)
      Right of (cM)
      Notes
      Stocks and Reagents
      Stocks (17)
      Genomic Clones (19)
       

      Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

      cDNA Clones (19)
       

      Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

      cDNA clones, fully sequenced
      BDGP DGC clones
      Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        Antibody Information
        Laboratory Generated Antibodies
         

        polyclonal

        (Gordon et al., 2017, Morelli et al., 2014, Xu et al., 2014, Takáts et al., 2013)
        Commercially Available Antibodies
         
        Cell Line Information
        Publicly Available Cell Lines
         
          Other Stable Cell Lines
           
            Other Comments

            Snap29 is required for the fusion of autophagosomes with degradative endocytic organelles. It is also required for proper Golgi apparatus morphology and has an inhibitory role in membrane fusion at the apical plasma membrane.

            (Morelli et al., 2014)

            Identification: as a protein that interacts strongly with Snap in a yeast two-hybrid system.

            (Xu et al., 1999)
            Relationship to Other Genes
            Source for database merge of

            Source for merge of: Snap29 pd

            (Dean et al., 2025)
            Additional comments

            The pd complementation group corresponds to one (or more) of the following annotated genes: CG4797, CR44807, CG5549, CG4763, snoRNA:Psi18S-176 , CR44805, Snap29.

            (Kahsai and Cook, 2018)
            Nomenclature History
            Source for database identify of

            Source for identity of: usnp CG11173

            (Boulianne, 2000.6.6)

            Source for identity of: Snap29 usnp

            (FlyBase, 2009-)
            Nomenclature comments

            Renamed from 'usnp' to 'Snap29' to better reflect usage in the literature and to improve consistency in naming of SNAP genes.

            (FlyBase, 2009-)
            Etymology
            Synonyms and Secondary IDs (15)
            Reported As
            Symbol Synonym
            CG11173
            (National Institute of Genetics Fly Stocks, 2023-, Hosono et al., 2015, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Perkins et al., 2009.1.15, Dorer et al., 2006, Bock, 2000.10.26, Boulianne, 2000.6.6, Niemeyer and Schwarz, 2000)
            MENE (2R)-E
            (Vaccari et al., 2009)
            MENE(2R)-E
            (Vaccari et al., 2009)
            SNAP-29
            (Zhang and Baehrecke, 2015, Dorer et al., 2006, Kirby et al., 2004, Littleton, 2000, Niemeyer and Schwarz, 2000)
            SNAP29
            (Dean et al., 2025, Deliu et al., 2022, Rong et al., 2022, Csizmadia and Juhász, 2020, Fujita et al., 2017, Kloepper et al., 2008)
            Snap29
            (Ochi et al., 2024, Hodgson et al., 2022, Kakanj et al., 2022, Xu et al., 2022, Parkhitko et al., 2021, Cunningham et al., 2020, Gohel et al., 2020, González-Méndez et al., 2020, Maurer et al., 2020, Murakawa et al., 2020, Xu et al., 2020, Kriegenburg et al., 2019, Meltzer et al., 2019, Poe et al., 2019, Texada et al., 2019, Csizmadia et al., 2018, Manent et al., 2017, Transgenic RNAi Project members, 2017-, Morelli et al., 2016, Morelli et al., 2014, Vaccari, 2014.8.4)
            Ubisnap
            (Xu et al., 1999)
            Usnp
            (Warecki et al., 2020, Stephano et al., 2018)
            dSNAP-29
            (Xu et al., 2014)
            pd
            (Dean et al., 2025, Kahsai and Cook, 2018, Wang et al., 2012, Anaka et al., 2008)
            snap29
            (González-Méndez et al., 2020, Robinson et al., 2020)
            ubisnap
            (Babcock et al., 2015, Mulakkal et al., 2014, Takáts et al., 2014)
            usnp
            (Lőrincz et al., 2016, Sarov et al., 2016, Takáts et al., 2014, Kwon et al., 2013, Oortveld et al., 2013, Takáts et al., 2013, Younger et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Hendrix et al., 2008, Stuart et al., 2007)
            Name Synonyms
            Synaptosomal-associated protein 29kDa
            Ubisnap
            (Przewloka et al., 2011)
            purpleoid
            (Anaka et al., 2008)
            ubisnap
            (Lőrincz et al., 2016, Hegedűs et al., 2013, Xu et al., 1999)
            Secondary FlyBase IDs
            • FBgn0003049
            • FBgn0034913
            Datasets (0)
            Study focus (0)
            Experimental Role
            Project
            Project Type
            Title
            Study result (0)
            Result
            Result Type
            Title
            External Crossreferences and Linkouts ( 21 )
            Sequence Crossreferences
            NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
            GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
            GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
            RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
            UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
            UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
            Other crossreferences
            AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
            DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
            EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
            FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
            InterPro - A database of protein families, domains and functional sites
            KEGG Genes - Molecular building blocks of life in the genomic space.
            MARRVEL_MODEL - MARRVEL (model organism gene)
            Linkouts
            FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
            Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
            References (114)