Price, M.A. (2006). CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling.  Genes Dev. 20(4): 399--410.

FBrf0191531

Review

Multiple members of the casein kinase I family of serine/threonine protein kinases are involved in positive and negative roles in Wnt and Hedgehog signaling. Here I review these roles, including recent results on casein kinase I (CKI) phosphorylation and activation of LRP6, and CKI phosphorylation of Ci and mediation of Ci-Slimb/beta-TrCP binding.