FlyBase Allele Report: Scer\GAL4[103Y]

FB2025_01 , released February 20, 2025

FB2025_01 , released February 20, 2025

Allele: Scer\GAL4^103Y

General Information

Symbol

Scer\GAL4^103Y

Species

S. cerevisiae

Name

FlyBase ID

FBal0066088

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Also Known As

103Y, P{GawB}103Y, 103Y-Gal4, P[Gal4]103Y

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Tettamanti et al., 1997)

Progenitor genotype

Associated Insertion(s)

Cytology

Description

Allele components

Component

Use(s)

Inserted element

Encoded product / tool

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

Kenyon cell | subset

(Tettamanti et al., 1997)

mushroom body | restricted

(Tettamanti et al., 1997)

mushroom body pedunculus | restricted

(Tettamanti et al., 1997)

third instar larval stage

brain | restricted

(Gatti et al., 2000)

larval ventral nerve cord | restricted

(Gatti et al., 2000)

(Armstrong et al., 1998)

adult mushroom body alpha-lobe

(Armstrong et al., 1998)

adult mushroom body beta-lobe

(Armstrong et al., 1998)

adult mushroom body gamma-lobe

(Armstrong et al., 1998)

adult mushroom body alpha'-lobe

(Armstrong et al., 1998)

protocerebrum | restricted

(Gatti et al., 2000)

mushroom body calyx

(Rosay et al., 2001)

Kenyon cell | subset

(Tettamanti et al., 1997)

ellipsoid body | restricted

(Gatti et al., 2000)

neuron of protocerebrum | subset

(Gatti et al., 2000)

adult central complex | restricted

(Gatti et al., 2000)

fan-shaped body | restricted

(Gatti et al., 2000)

neuron | subset

(Gatti et al., 2000)

(Rosay et al., 2001)

lobe system of mushroom body | restricted

(Tettamanti et al., 1997)

adult mushroom body alpha-lobe

(Armstrong et al., 1998)

adult mushroom body beta-lobe

(Armstrong et al., 1998)

adult mushroom body

(Suh et al., 2004, Belgacem and Martin, 2002, Rosay et al., 2001, Gatti et al., 2000, Armstrong et al., 1998)

adult antennal lobe

(Gatti et al., 2000)

gamma Kenyon cell

(Pauls et al., 2010)

alpha/beta Kenyon cell

(Pauls et al., 2010)

alpha'/beta' Kenyon cell

(Pauls et al., 2010)

adult mushroom body gamma-lobe

(Pauls et al., 2010, Armstrong et al., 1998)

adult mushroom body alpha'-lobe

(Pauls et al., 2010, Armstrong et al., 1998)

mushroom body beta lobe core layer

(Aso et al., 2009)

mushroom body alpha lobe core layer

(Aso et al., 2009)

(Aso et al., 2009)

anterior optic tubercle

(Aso et al., 2009)

glial cell of adult brain | faint

(Aso et al., 2009)

adult mushroom body alpha-lobe

(Pauls et al., 2010)

adult mushroom body beta-lobe

(Pauls et al., 2010)

adult mushroom body beta'-lobe

(Pauls et al., 2010)

adult stage | male

adult mushroom body gamma-lobe

(Aso et al., 2009)

mushroom body beta lobe surface layer | intense

(Aso et al., 2009)

mushroom body alpha lobe surface layer | intense

(Aso et al., 2009)

mushroom body beta lobe posterior layer | intense

(Aso et al., 2009)

mushroom body alpha lobe posterior layer | intense

(Aso et al., 2009)

mushroom body beta' anterior-posterior layer | intense

(Aso et al., 2009)

mushroom body alpha' middle layer | faint

(Aso et al., 2009)

mushroom body beta' middle layer | faint

(Aso et al., 2009)

mushroom body alpha' anterior-posterior layer | intense

(Aso et al., 2009)

adult antennal lobe

(Aso et al., 2009)

fan-shaped body | faint

(Aso et al., 2009)

(Aso et al., 2009)

(Aso et al., 2009)

adult protocerebrum | restricted

(Aso et al., 2009)

inferior neuropils | faint

(Aso et al., 2009)

adult lateral horn | faint

(Aso et al., 2009)

adult antennal nerve | faint

(Aso et al., 2009)

adult deutocerebrum | faint

(Aso et al., 2009)

adult tritocerebrum | faint

(Aso et al., 2009)

adult gnathal ganglion | faint

(Aso et al., 2009)

adult pars intercerebralis | faint

(Aso et al., 2009)

Additional Information

Statement

Reference

Adult expression is observed in the mushroom body and antennal lobe, in a band in the fan-shaped body, in a ring around the ellipsoid body of the central body complex, and in scattered neurons in the protocerebrum. Third instar larval expression is seen in various parts of the brain and in the thoracic ganglia.

(Gatti et al., 2000)

Larval expression begins abruptly at hatching, and is observed in most of the mushroom body, except at the core of Kenyon cells clusters, and in the stalk of the mushroom body with 2-fold concentric organization.

(Tettamanti et al., 1997)

Marker for

(Rosay et al., 2001)

(Suh et al., 2004, Belgacem and Martin, 2002, Gatti et al., 2000)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | male, with tra^UAS.cFa

(Belgacem and Martin, 2002)

abnormal sleep | adult stage | female limited, with tra2^GD768

(Khericha et al., 2016)

partially lethal - majority die | female limited | heat sensitive, with Zzzz\CTG^i480.UAS.cGa

(Garcia-Lopez et al., 2008)

some die during pupal stage | female limited | heat sensitive, with Zzzz\CTG^i480.UAS.cGa

(Garcia-Lopez et al., 2008)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^103Y, Zzzz\CTG^i480.UAS.cGa has partially lethal - majority die | pupal stage | female limited | heat sensitive phenotype, enhanceable by mbl[+]/mbl^E27

(Garcia-Lopez et al., 2008)

Suppressed by

Statement

Reference

Scer\GAL4^103Y, tra^UAS.cFa has abnormal locomotor behavior | male phenotype, suppressible by oc¹

(Belgacem and Martin, 2002)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to rescue

homer^UAS.Tag:MYC/Scer\GAL4^103Y fails to rescue homer^R102

(Urizar et al., 2007)

Adcy1^UAS.cZa/Scer\GAL4^103Y fails to rescue Adcy1^rut-2080

(Zars et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

30813

P{GawB}103Y w^*

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^103Y

Scer\GAL4^103Y

Name Synonyms

Secondary FlyBase IDs

References (16)

Report Sections