FB2025_01 , released February 20, 2025
Gene Group: RNA ENDONUCLEASES
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General Information
Name
RNA ENDONUCLEASES
Species
D. melanogaster
Symbol
ERNASE
FlyBase ID
FBgg0001480
Date last reviewed
2020-06-16
Number of members
52
Description
Description
Endoribonucleases catalyze the cleavage of phosphodiester bonds within the middle of ribonucleic acid chain by creating internal breaks.
Notes on Group
Source Material
The RNA ENDONUCLEASES Gene Group has been compiled using the following publication(s): Schmidt et al., 2019, Azlan et al., 2016, Xie and Dubrovsky, 2015, Lim et al., 2008, Lee et al., 2004, Bernstein et al., 2001, and Filippov et al., 1997 .
Key Gene Ontology (GO) terms
Molecular Function
RNA endonuclease activity
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
RIBONUCLEASES
Component group(s)
3'-TRNA PROCESSING ENDORIBONUCLEASES
ARGONAUTE ENDORIBONUCLEASES
RIBONUCLEASES III
RIBONUCLEASE T2S
RNA-DNA HYBRID RIBONUCLEASES
RNA LARIAT DEBRANCHING ENZYMES
TRNA-INTRON ENDONUCLEASES
UNCLASSIFIED RNA ENDONUCLEASES
Members (52)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
3'-TRNA PROCESSING ENDORIBONUCLEASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
RNaseZ
Ribonuclease Z
JhI-1, dRNaseZ, tRNase Z, Juvenile hormone-inducible protein 1, RNZ
(FlyBase, 2017-, Xie and Dubrovsky, 2015)
ARGONAUTE ENDORIBONUCLEASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
AGO1
Argonaute-1
Ago-1, Argonaute, dAGO1, l(2)04845, MRE20
(FlyBase, 2017-, Azlan et al., 2016)
AGO2
Argonaute 2
Ago-2, dAgo2, Argonaute, DmAgo2
(FlyBase, 2017-, Azlan et al., 2016)
AGO3
Argonaute 3
Ago-3, BEST:LD15785
(FlyBase, 2017-, Azlan et al., 2016)
aub
aubergine
sting, stellate-interacting gene
(FlyBase, 2017-, Azlan et al., 2016)
piwi
P-element induced wimpy testis
(FlyBase, 2017-, Azlan et al., 2016)
RIBONUCLEASES III
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Dcr-1
Dicer-1
Dicer, Dcr1
(FlyBase, 2017-, Lee et al., 2004, Bernstein et al., 2001)
Dcr-2
Dicer-2
Dcr2, Dicer, dmDcr-2, dcr
(FlyBase, 2017-, Lim et al., 2008, Lee et al., 2004)
drosha
drosha
(FlyBase, 2017-)
RIBONUCLEASE T2S
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
RNaseX25
Ribonuclease X25
DmRNase-X25, RNase X25
(FlyBase, 2017-)
RNA-DNA HYBRID RIBONUCLEASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG13690
(FlyBase, 2017-)
Fen1
Flap endonuclease 1
EG:EG0003.3
(FlyBase, 2017-)
rnh1
ribonuclease H1
RNase H1, l(2)43F1-5, l(2)k07624
(FlyBase, 2017-, Filippov et al., 1997)
RNA LARIAT DEBRANCHING ENZYMES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
ldbr
lariat debranching enzyme
(FlyBase, 2017-)
TRNA-INTRON ENDONUCLEASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Tsen2
tRNA splicing endonuclease subunit 2
(Schmidt et al., 2019, FlyBase, 2017-)
Tsen34
tRNA splicing endonuclease subunit 34
(Schmidt et al., 2019, FlyBase, 2017-)
UNCLASSIFIED RNA ENDONUCLEASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Arlr
Age-related lipid regulator
(FlyBase, 2017-)
CG2972
(FlyBase, 2017-)
CG3819
(FlyBase, 2017-)
CG6839
(FlyBase, 2017-)
CG9117
(FlyBase, 2017-)
CG11269
(FlyBase, 2017-)
CG12375
(FlyBase, 2017-)
CG12917
(FlyBase, 2017-)
CG14062
(FlyBase, 2017-)
CG14118
(FlyBase, 2017-)
CG14120
(FlyBase, 2017-)
CG33346
(FlyBase, 2017-)
CG42360
(FlyBase, 2017-)
Clp
Clipper
CPSF30, c6a
(FlyBase, 2017-)
Cpsf73
Cleavage and polyadenylation specificity factor 73
CPSF-73
(FlyBase, 2017-)
Dis3
Dis3
dDis3, Tazman
(FlyBase, 2017-)
EndoG
Endonuclease G
(FlyBase, 2017-)
EndoU
Endoribonuclease U-specific
dendoU
(FlyBase, 2017-)
IntS11
Integrator 11
(FlyBase, 2017-)
Ire1
Inositol-requiring enzyme-1
ire-1, Ire1α, Ire
(FlyBase, 2017-)
mldr
mulder
(FlyBase, 2017-)
pelo
pelota
(FlyBase, 2017-)
Regnase-1
Regnase 1
(FlyBase, 2017-)
RNASEK
Ribonuclease kappa
l(2)NC110
(FlyBase, 2017-)
RNaseMRP:RNA
Ribonuclease MRP RNA
RNase MRP, snmRNA:342, MRP RNA
(FlyBase, 2017-)
RNaseP:RNA
Ribonuclease P RNA
RNase P RNA
(FlyBase, 2017-)
Rtc1
Rtc1
(FlyBase, 2017-)
Sid
Stress induced DNase
(FlyBase, 2017-)
Smg6
Smg6
(FlyBase, 2017-)
Swt1
Swt1 RNA endoribonuclease
(FlyBase, 2017-)
Tengl1
Testis EndoG-Like 1
(FlyBase, 2017-)
Tengl2
Testis EndoG-Like 2
(FlyBase, 2017-)
Tengl3
Testis EndoG-Like 3
(FlyBase, 2017-)
Tengl4
Testis EndoG-Like 4
(FlyBase, 2017-)
Trax
Translin associated factor X
(FlyBase, 2017-)
zuc
zucchini
MitoPLD
(FlyBase, 2017-)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
ERNASE
RNA ENDONUCLEASES
ENDORIBONUCLEASES
Secondary FlyBase ID(s)
References (9)