FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2L)spd
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General Information
Symbol
Df(2L)spd
Species
D. melanogaster
Name
Deficiency (2L) spade
FlyBase ID
FBab0001917
Feature type
chromosomal_deletion
Also Known As
Df(2L)spdX4
Computed Breakpoints include

27E;28C1-28C4

Features within 27E1--28B3
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Landecker et al., 1994)
deficient_inversion
(Bloomington Drosophila Stock Center, 2003.3.31)
Breakpoints

27D-27E;28C

(Landecker et al., 1994)

27E;28C

(Duffy et al., 1996, Harbecke and Lengyel, 1995)

27E1-27E3;28B1-28B3;26A6-26B1

(Bloomington Drosophila Stock Center, 2003.3.31)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

eIF-4a << bk1 << wg << cuc << bk2 << l(2)rL220

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0082073) Right limit of break 1 from polytene analysis (FBrf0076124) Left limit of break 2 from polytene analysis (FBrf0076124) Right limit of break 2 from non-inclusion of l(2)rL220 (FBrf0067338)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    Fails to complement Df(2L)TE29Aa-11.

    (Cox et al., 2000)
    NOT in combination with other aberrations

    Heterozygosity for Df(2L)spd results in 2.0% X chromosome nondisjunction and 0.2% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    (Harris et al., 2003)

    Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

    (Coyne et al., 1998)

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    (Halsell and Kiehart, 1998)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Deficient embryos show an uninterpretable mutant midgut phenotype.

    (Bilder and Scott, 1995)

    Homozygous embryos are very abnormal compared to wild-type and have no obvious segmentation. The hindgut is very short or absent, and the Malpighian tubules are either absent or show very short outbuddings.

    (Harbecke and Lengyel, 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)
    Stocks (2)
    Notes on Origin
    Discoverer

    E.H. Grell.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2L)spd chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(2L)spd overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing.

    (Mason et al., 2004)

    "27E1--3;28B1--3;26A6--B1" was stated as revision. "deficient_inversion ; SO:1000171" was stated as revision.

    (Bloomington Drosophila Stock Center, 2003.3.31)
    Synonyms and Secondary IDs (7)
    Reported As
    Symbol Synonym
    Df(2)spd
    (Fanara et al., 2002)
    Df(2L)spd
    (Bejarano et al., 2008, Learte et al., 2008, Tanaka and Nakamura, 2008, Crest et al., 2007)
    Df(2L)spd-X4
    Df(2L)spdX4
    (Tran and Berg, 2003, Duffy et al., 1996, Bilder and Scott, 1995, Pauli et al., 1995)
    Df(2L)spdx4
    (Abrell et al., 2000, Harbecke and Lengyel, 1995)
    Df(3L)Spd
    (Greaves et al., 1999)
    Name Synonyms
    Deficiency (2L) spade
    Secondary FlyBase IDs
      References (31)