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General Information
Symbol
Dmel\pydtam
Species
D. melanogaster
Name
FlyBase ID
FBal0051070
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
pydtam1, pydtamou
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{BmΔ-w} insertion just 5' to the first (non-coding) exon.

Insertion components
P{BmΔ-w}pydtam
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

70% of pydtam/pydC5 flies display more than four dorsocentral macrochaetae.

Over 80% of pydtam/Df(3R)p-XT103 flies display more than four dorsocentral macrochaetae.

Wings from pydtam/Df(3R)p-XT103 flies are broader compared to control wings. A 5-10% increase in the number of cells found between the L3 and L4 veins is observed.

Wings from pydex147/pydtam flies are broader compared to control wings.

pydtam mutants display an increase in the number of ovarian niche cap cells.

Homozygous embryos develop normally. Homozygous adults have a normal dorsal thorax. Homozygous hep1 adults show slight widening of the dorsal thorax.

Ectopic macrochaetae are present on the dorsal surface of the adult head and thorax. Extra sensilla campaniformia develop on the wing vein.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhanced by
Statement
Reference

pydtam/pydex147 has visible phenotype, non-enhanceable by N[+]/N55e11

Enhancer of
Statement
Reference

pydtam is an enhancer of visible | recessive phenotype of hep1

NOT Enhancer of
Statement
Reference

pydtam/pyd[+] is a non-enhancer of visible | adult stage phenotype of MagiUAS.GFP, Scer\GAL4GMR.PU

NOT Suppressor of
Statement
Reference

pydtam/pyd[+] is a non-suppressor of visible | adult stage phenotype of MagiUAS.GFP, Scer\GAL4GMR.PU

Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

pydtam/pydex147 has wing phenotype, enhanceable by ex[+]/exe1

NOT Enhanced by
Statement
Reference

pydtam/pydex147 has wing phenotype, non-enhanceable by Cdk43/Cdk4[+]

pydtam/pydex147 has wing phenotype, non-enhanceable by Cdk4k06503/Cdk4[+]

pydtam/pydex147 has wing phenotype, non-enhanceable by Tor[+]/TorΔP

pydtam/pydex147 has wing phenotype, non-enhanceable by Ptendj189/Pten[+]

pydtam/pydex147 has wing phenotype, non-enhanceable by Ptenc494/Pten[+]

pydtam/pydex147 has wing phenotype, non-enhanceable by Su(dx)sp/Df(2L)Exel6006

pydtam/pydex147 has wing phenotype, non-enhanceable by N[+]/N55e11

pydtam/pydex147 has wing phenotype, non-enhanceable by Su(H)8/Su(H)[+]

pydtam/pydex147 has wing phenotype, non-enhanceable by Su(dx)sp/Su(dx)[+]

pydtam/pydex147 has wing phenotype, non-enhanceable by yps[+]/ypsJM2

pydtam has phenotype, non-enhanceable by a7/Df(2R)aEX1

NOT suppressed by
Statement
Reference

pydtam has phenotype, non-suppressible by a7/Df(2R)aEX1

Enhancer of
Statement
Reference

pydtam is an enhancer of adult thorax | dorsal phenotype of hep1

pydtam is an enhancer of adult thorax & adult cuticle | dorsal phenotype of hep1

NOT Enhancer of
Statement
Reference

pydtam/pyd[+] is a non-enhancer of eye | adult stage phenotype of MagiUAS.GFP, Scer\GAL4GMR.PU

NOT Suppressor of
Statement
Reference

pydtam/pyd[+] is a non-suppressor of eye | adult stage phenotype of MagiUAS.GFP, Scer\GAL4GMR.PU

Other
Additional Comments
Genetic Interactions
Statement
Reference

The rough eye phenotype observed in adults expressing MagiScer\UAS.T:Avic\GFP under the control of Scer\GAL4GMR.PU is not modified by combination with single copy of pydtam.

100% of N55e11/+; pydtam/pydC5 flies display more than four dorsocentral macrochaetae.

The broader wings observed in pydex147/pydtam flies are not enhanced in a N55e11/+ background.

Wings from pydex147/pydtam flies are broader compared to control wings, and this phenotype is enhanced in a exe1/+ background.

Wings from pydex147/pydtam flies are broader compared to control wings, and this phenotype is not modified in a Su(H)8/+, Su(dx)sp/+, ypsJM2/+, Cdk43/+, Cdk4k06503/+, TorΔP/+, Ptendj189/+, or Ptenc494/+ background.

Wings from pydex147/pydtam flies are broader compared to control wings, and this phenotype is not modified in a Su(dx)sp/Df(2L)Exel6006 background.

The addition of pydtam/+ has no effect on a7/Df(2R)aEX1 flies.

pydtam cnomis1 double heterozygotes die as embryos with a dorsal open phenotype. The leading edge cells show little elongation during stage 15 (at or slightly before completion of dorsal closure). The dorsal thoracic cuticle of hep1 homozygous adults is severely disrupted in a pydtam homozygous background.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments

The number of pydtam/pydC5 flies displaying an increased number of dorsocentral macrochaete is reduced when pydScer\UAS.T:Avic\GFP is expressed under the control of Scer\GAL4sca-537.4.

The number of pydtam/pydC5 flies displaying an increased number of dorsocentral macrochaete is reduced when pydΔPDZ1.Scer\UAS.T:Avic\GFP is expressed under the control of Scer\GAL4sca-537.4.

The number of pydtam/pydC5 flies displaying an increased number of dorsocentral macrochaete is not reduced when pydΔPDZ2.Scer\UAS.T:Avic\GFP is expressed under the control of Scer\GAL4sca-537.4.

The number of pydtam/pydC5 flies displaying an increased number of dorsocentral macrochaete is not reduced when pydΔPDZ3.Scer\UAS.T:Avic\GFP is expressed under the control of Scer\GAL4sca-537.4.

The number of pydtam/pydC5 flies displaying an increased number of dorsocentral macrochaete is not reduced when pydΔGUK.Scer\UAS.T:Avic\GFP is expressed under the control of Scer\GAL4sca-537.4.

The number of pydtam/pydC5 flies displaying an increased number of dorsocentral macrochaete is not reduced when pydΔEx6.Scer\UAS.T:Avic\GFP is expressed under the control of Scer\GAL4sca-537.4. A more severe bristle phenotype is observed in these animals.

The number of pydtam/pydC5 flies displaying an increased number of dorsocentral macrochaete is partially reduced when pydΔSH3.Scer\UAS.T:Avic\GFP is expressed under the control of Scer\GAL4sca-537.4.

The number of pydtam/pydC5 flies displaying an increased number of dorsocentral macrochaete is partially reduced when pydΔPro-Rich.Scer\UAS.T:Avic\GFP is expressed under the control of Scer\GAL4sca-537.4.

The increased size of adult wings in pydex147/pydtam mutant flies is restored in animals expressing pydScer\UAS.T:Avic\GFP under the control of Scer\GAL4Act5C.PU.

The increased size of adult wings in pydex147/pydtam mutant flies is restored in animals expressing pydΔPDZ1.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4Act5C.PU.

The increased size of adult wings in pydex147/pydtam mutant flies is restored in animals expressing pydΔEx6.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4Act5C.PU.

The increased size of adult wings in pydex147/pydtam mutant flies is not restored in animals expressing pydΔPDZ2.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4Act5C.PU.

The increased size of adult wings in pydex147/pydtam mutant flies is not restored in animals expressing pydΔSH3.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4Act5C.PU.

The increased size of adult wings in pydex147/pydtam mutant flies is not restored in animals expressing pydΔGUK.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4Act5C.PU.

The increased size of adult wings in pydex147/pydtam mutant flies is not restored in animals expressing pydΔPro-Rich.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4Act5C.PU.

The increased size of adult wings in pydex147/pydtam mutant flies is partially restored in animals expressing pydΔPDZ3.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4Act5C.PU.

pydhs.PT rescues the extra bristle phenotype of pydtam.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
References (10)