FlyBase Allele Report: Dmel\mam[g2.1]

General Information

Symbol

Dmel\mam^g2.1

Species

D. melanogaster

Name

FlyBase ID

FBal0056511

Feature type

allele

Associated gene

Dmel\mam

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

gamma ray

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Morcillo et al., 1996)

Mutagen

gamma ray

(Morcillo et al., 1996)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

wing margin

(Gause et al., 2006)

Detailed Description

Statement

Reference

Heterozygotes have rare nicks in the wing margin.

(Gause et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

mam^g2.1 has visible | dominant phenotype, enhanceable by Df(2R)Nipped-C160.1

(Rollins et al., 1999)

mam^g2.1 has visible | dominant phenotype, enhanceable by +/T(2;3)Nipped-C138.2

(Rollins et al., 1999)

mam^g2.1 has visible | dominant phenotype, enhanceable by Df(2R)Nipped-D341.1/+

(Rollins et al., 1999)

mam^g2.1 has visible | dominant phenotype, enhanceable by Df(2R)Nipped-D263.3/+

(Rollins et al., 1999)

mam^g2.1 has visible | dominant phenotype, enhanceable by Df(2R)Nipped-E299.1/+

(Rollins et al., 1999)

mam^g2.1 has visible | dominant phenotype, enhanceable by Df(2R)Nipped-E43/+

(Rollins et al., 1999)

mam^g2.1 has visible | dominant phenotype, enhanceable by Df(2R)Nipped-E338/+

(Rollins et al., 1999)

Other

Statement

Reference

RpL38[+]/RpL38^45-72, mam^g2.1 has visible | dominant phenotype

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A³²³, mam^g2.1 has visible | dominant phenotype

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A², mam^g2.1 has visible | dominant phenotype

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A^222.3, mam^g2.1 has visible | dominant phenotype

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A^394.2, mam^g2.1 has visible | dominant phenotype

(Rollins et al., 1999)

Nipped-B[+]/Nipped-B⁴, mam^g2.1 has visible | dominant phenotype

(Rollins et al., 1999)

Nipped-B[+]/Nipped-B^292.1, mam^g2.1 has visible | dominant phenotype

(Rollins et al., 1999)

ct^53d, mam^g2.1/mam[+] has visible phenotype

(Morcillo et al., 1996)

Phenotype Manifest In

Enhanced by

Statement

Reference

mam^g2.1 has wing margin phenotype, enhanceable by Nipped-A[+]/Nipped-A³²³

(Gause et al., 2006)

mam^g2.1 has wing margin phenotype, enhanceable by Nipped-A[+]/Nipped-A^NC106

(Gause et al., 2006)

mam^g2.1 has wing margin phenotype, enhanceable by Ada2b[+]/Ada2b^HD-5

(Gause et al., 2006)

mam^g2.1 has wing margin phenotype, enhanceable by Ada2b[+]/Ada2b¹

(Gause et al., 2006)

mam^g2.1 has wing margin phenotype, enhanceable by Ada2b[+]/Ada2b²

(Gause et al., 2006)

mam^g2.1 has wing margin phenotype, enhanceable by dom^k08108/dom[+]

(Gause et al., 2006)

mam^g2.1 has phenotype, enhanceable by Nipped-A^222.3

(Rollins et al., 1999)

mam^g2.1 has wing phenotype, enhanceable by Df(2R)Nipped-C160.1

(Rollins et al., 1999)

mam^g2.1 has wing phenotype, enhanceable by +/T(2;3)Nipped-C138.2

(Rollins et al., 1999)

mam^g2.1 has wing phenotype, enhanceable by Df(2R)Nipped-D341.1/+

(Rollins et al., 1999)

mam^g2.1 has wing phenotype, enhanceable by Df(2R)Nipped-D263.3/+

(Rollins et al., 1999)

mam^g2.1 has phenotype, enhanceable by Nipped-A²

(Rollins et al., 1999)

mam^g2.1 has wing phenotype, enhanceable by Df(2R)Nipped-E299.1/+

(Rollins et al., 1999)

mam^g2.1 has wing phenotype, enhanceable by Df(2R)Nipped-E43/+

(Rollins et al., 1999)

mam^g2.1 has wing phenotype, enhanceable by Df(2R)Nipped-E338/+

(Rollins et al., 1999)

mam^g2.1 has phenotype, enhanceable by Nipped-A³²³

(Rollins et al., 1999)

mam^g2.1 has phenotype, enhanceable by Nipped-A^394.2

(Rollins et al., 1999)

mam^g2.1 has phenotype, enhanceable by Nipped-B^292.1

(Rollins et al., 1999)

mam^g2.1 has phenotype, enhanceable by Nipped-B⁴

(Rollins et al., 1999)

mam^g2.1 has phenotype, enhanceable by RpL38^45-72

(Rollins et al., 1999)

NOT Enhanced by

Statement

Reference

mam^g2.1 has wing margin phenotype, non-enhanceable by Nipped-A[+]/Nipped-A^NC96

(Gause et al., 2006)

mam^g2.1 has wing margin phenotype, non-enhanceable by Nipped-A[+]/Nipped-A^NC105

(Gause et al., 2006)

mam^g2.1 has wing margin phenotype, non-enhanceable by Nipped-A[+]/Nipped-A^NC186

(Gause et al., 2006)

mam^g2.1 has wing margin phenotype, non-enhanceable by Nipped-A[+]/Nipped-A^NC194

(Gause et al., 2006)

mam^g2.1 has phenotype, non-enhanceable by Nipped-B^359.1

(Rollins et al., 1999)

mam^g2.1 has phenotype, non-enhanceable by Nipped-B⁴⁰⁷

(Rollins et al., 1999)

Enhancer of

Statement

Reference

mam^g2.1 is an enhancer of phenotype of ct^53d

(Morcillo et al., 1996)

mam^g2.1/mam[+] is an enhancer of wing phenotype of ct^L32, su(Hw)^e2

(Morcillo et al., 1996)

Other

Statement

Reference

Nipped-A^222.3, mam^g2.1/mam[+] has wing phenotype

(Rollins et al., 1999)

Nipped-A², mam^g2.1/mam[+] has wing phenotype

(Rollins et al., 1999)

RpL38[+]/RpL38^45-72, mam^g2.1 has wing phenotype

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A³²³, mam^g2.1 has wing phenotype

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A², mam^g2.1 has wing phenotype

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A^222.3, mam^g2.1 has wing phenotype

(Rollins et al., 1999)

Nipped-A³²³, mam^g2.1/mam[+] has wing phenotype

(Rollins et al., 1999)

Nipped-A[+]/Nipped-A^394.2, mam^g2.1 has wing phenotype

(Rollins et al., 1999)

Nipped-B[+]/Nipped-B⁴, mam^g2.1 has wing phenotype

(Rollins et al., 1999)

Nipped-B[+]/Nipped-B^292.1, mam^g2.1 has wing phenotype

(Rollins et al., 1999)

Nipped-A^394.2, mam^g2.1/mam[+] has wing phenotype

(Rollins et al., 1999)

Nipped-B^292.1, mam^g2.1/mam[+] has wing phenotype

(Rollins et al., 1999)

Nipped-B⁴, mam^g2.1/mam[+] has wing phenotype

(Rollins et al., 1999)

RpL38^45-72, mam^g2.1/mam[+] has wing phenotype

(Rollins et al., 1999)

Chi^e5.5, mam^g2.1 has wing phenotype

(Morcillo et al., 1996)

ct^L32, mam^g2.1/mam[+] has wing phenotype

(Morcillo et al., 1996)

ct^L32, mam^g2.1/mam[+] has wing margin phenotype

(Morcillo et al., 1996)

ct^L32/ct[+], mam^g2.1 has wing phenotype

(Morcillo et al., 1996)

ct^2s/ct[+], mam^g2.1 has wing phenotype

(Morcillo et al., 1996)

ct^53d/ct[+], mam^g2.1 has wing phenotype

(Morcillo et al., 1996)

Chi[+]/Chi^e5.5, mam^g2.1 has wing phenotype

(Morcillo et al., 1996)

ct^2s, mam^g2.1 has wing phenotype

(Morcillo et al., 1996)

ct^53d, mam^g2.1/mam[+] has wing phenotype

(Morcillo et al., 1996)

Additional Comments

Genetic Interactions

Statement

Reference

Heterozygosity for Nipped-A³²³ or Nipped-A^NC106 increases the number of wing margin nicks seen in mam^g2.1 heterozygotes.

Heterozygosity for Ada2b^HD-5, Ada2b¹, Ada2b² or dom^k08108 increases the number of wing margin nicks seen in mam^g2.1 heterozygotes.

(Gause et al., 2006)

Heterozygotes show a cut wing phenotype in combination with mutants in the 'Nipped' genes.

(Rollins et al., 1999)

Dominant enhancer of the ct^L32; su(Hw)^e2 wing phenotype. Chi^e5.5; mam^g2.1 double heterozygotes display a partial cut wing phenotype. mam^g2.1; ct^L32, mam^g2.1; ct^2s and mam^g2.1; ct^53d double heterozygotes display a visible cut wing phenotype.

(Morcillo et al., 1996)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

mam^g2.1 mutants are more sensitive to ct wing margin enhancer deletions that gypsy insertions in ct.

(Morcillo et al., 1996)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

mam^g2.1

mam^g2

(Gause et al., 2006)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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