The co-expression of Nulp1PA.UAS greatly suppresses the notched wings and the truncated longitudinal veins (except for some defects in L4) induced by the expression of expression of Nulp1PA.UAS under the control of Scer\GAL4salm.E.
The increased number of intestinal progenitor cells in mitosis characteristic for adult flies expressing sggA81T.Scer\UAS driven by Scer\GAL4esg-NP7397 (combined with tub-Gal80[ts] for temporal control) is suppressed by co-expression of RetGD45.
Co-expression of sggA81T.Scer\UAS and MadScer\UAS.cNa under the control of Scer\GAL4sca-537.4 results in wings with ectopic sensilla on a slightly thickened L3 vein and ectopic mechanosensory bristles on the dorsal margin.
Co-expression of bskK53R.Scer\UAS and sggA81T.Scer\UAS pan-neuronally under the control of Scer\GAL4elav-C155 severely and significantly reduces synapse size compared to synapses in Scer\GAL4elav-C155-sggA81T.Scer\UAS flies.
Expression of sggA81T.Scer\UAS under the control of Scer\GAL4OK6, in a futschK68 background shows the futschK68 phenotype in which larval neuromuscular synaptic bouton number is decreased and not the opposite sggA81T.Scer\UAS overexpression phenotype.
Expression of sggA81T.Scer\UAS under the control of Scer\GAL4OK6, in a futschN94 background suppresses the increased larval neuromuscular bouton number phenotype, seen when sggA81T.Scer\UAS is expressed in a wild-type background. The phenotype is nearer to that seen in futschN94 single mutants, although the bouton number is not decreased as much.
Co-expression of sggA81T.Scer\UAS restores dendritic patterns caused by Scer\GAL4Ddc.PL>Hsap\LRRK2G2019S.Scer\UAS.cLa.T:Zzzz\FLAG. In addition, sggA81T.Scer\UAS suppresses the life-span and locomotion defects caused by Scer\GAL4Ddc.PL>Hsap\LRRK2G2019S.Scer\UAS.cLa.T:Zzzz\FLAG.