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General Information
Symbol
Dmel\Gugunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0131792
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Homozygous somatic clones in the wing lead to a number of defects, including notched wing margins and ectopic vein material. Clones of mutant cells in the intervein regions also alter the hair polarity of the surrounding wild-type cells. In the notum, mutant clones cause notal clefts. In the eye, mutant clones cause small and rough eye. Incorrect rotational direction is seen in wild-type ommatidia adjacent to the clone. Furthermore, both ommatidia rotation and organisation within the mutant eye clone becomes disorganised, with some ommatidia missing outer photoreceptor cells, while others contain extra cells or abnormally shaped rhabdomeres. In embryos lacking maternal Gug, about half fail to develop, all those that do develop have missing and misshaped ventral denticle belts, about 2/3 have holes and patches of naked cuticle. Amongst the embryos with at least one complete ventral denticle belt (just over half) a quarter have obviously widened belts. Hyperplasia of neuronal tissue is also seen in these embryos.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    NOT Enhanced by
    Statement
    Reference
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Rescued by
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Atrounspecified
    Gugunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (1)