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General Information
Symbol
Scer\GAL4S3.Hug
Species
S. cerevisiae
Name
FlyBase ID
FBal0198094
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
hugin-Gal4, HugS3-GAL4, hug-GAL4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 1.5kb Hug promoter fragment regulates expression of a GAL4 driver.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Associated Sequence Features
Expression Data
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Inhibition (using Hsap\KCNJ2UAS.EGFP) or ablation (using rprUAS.C) of Scer\GAL4S3.Hug cells in adults significantly reduces the strength of circadian locomotor rhythms under constant darkness, compared to controls; inhibition (using Hsap\KCNJ2UAS.EGFP) significantly reduces evening peak activity under light-dark and dark-dark conditions, compared to controls, with little effect on feeding rhythms.

Thermogenetic activation (using TrpA1UAS.(B).cKa at 32[o]C) of Scer\GAL4S3.Hug cells in larvae reduces food intake and pharyngeal pump cycle frequency (antennal nerve activity and cibarial dilator musculature contractions), compared to controls.

Ablation (using rprUAS.cUa) of Scer\GAL4S3.Hug cells in adult males does not affect food intake, compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to rescue
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Scer\GAL4S3.Hug
Scer\GAL4S3.hug
Name Synonyms
Secondary FlyBase IDs
    References (23)