Expression of th^{Scer\UAS.T:Hsap\MYC.cBa} partially rescues the eye phenotypes seen when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^GMR.PF at 29[o]C. Eye size is restored to 75% and 87% of controls in males and females respectively. Eyes still appear rough and shape is disrupted.

Expression of BacA\p35^{Scer\UAS.P\T.cBa} partially rescues the eye phenotypes seen when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^GMR.PF at 24[o]C. In females the resulting eye size is comparable to wild type, whereas males eyes are ~85% the size of those in wild type flies. Eyes still appear rough and shape remains disrupted.

Expression of Zzzz\E4orf4^Scer\UAS.cPa suppresses the semi-viability seen when W^Scer\UAS.cUa is expressed under the control of Scer\GAL4^GMR.PF at 18[o]C. 95% of pupae eclose (compared to 69%). The reduction in eye size is also partially suppressed.

Expression of Zzzz\E4orf4^Scer\UAS.cPa partially suppresses the semi-lethality seen when rpr^Scer\UAS.C is expressed under the control of Scer\GAL4^GMR.PF at 18[o]C. 78% of pupae eclose (compared to 32.5%). The reduction in eye size is also partially suppressed.

Expression of Zzzz\E4orf4^Scer\UAS.cPa partially suppresses the semi-lethality seen when rpr^Scer\UAS.cZa is expressed under the control of Scer\GAL4^GMR.PF at 18[o]C. 27.4% of pupae eclose (compared to 0.5%). The reduction in eye size is also partially suppressed.

Expression of Zzzz\E4orf4^Scer\UAS.cPa suppresses the semi-lethality seen when grim^Scer\UAS.cUa is expressed under the control of Scer\GAL4^GMR.PF at 18[o]C. 78% of pupae eclose (compared to 0.01%). The reduction in eye size is also partially suppressed.

Expression of Zzzz\E4orf4^Scer\UAS.cPa suppresses the lethality seen when egr^Scer\UAS.cIa is expressed under the control of Scer\GAL4^GMR.PF; 99% of adults eclose at 18[o]C, 100% at 24[o]C and 94% at 29[o]C.

Expression of Zzzz\E4orf4^Scer\UAS.cPa partially suppresses the reduction in eye size seen when egr^Scer\UAS.cIa is expressed under the control of Scer\GAL4^GMR.PF at 18[o]C. Eye size is increased to 39% in females (from 13%) and 53% in males (from 26%).

Expression of Zzzz\E4orf4^Scer\UAS.cPa partially rescues the eye phenotypes seen when hep^Act.Scer\UAS is expressed under the control of Scer\GAL4^GMR.PF at 18[o]C. Eye size is restored to 23% and 31% of controls in females and males respectively (from 19% in each).

Expression of Zzzz\E4orf4^Scer\UAS.cPa partially rescues the eye phenotypes seen when hep^CA.Scer\UAS is expressed under the control of Scer\GAL4^GMR.PF at 18[o]C. Eye size is restored to 25% and 31% of controls in females and males respectively (from 17% and 18%).

Expression of Zzzz\E4orf4^Scer\UAS.cPa has little effect on the reduced eclosion rates seen when hep^CA.Scer\UAS is expressed under the control of Scer\GAL4^GMR.PF at 18[o]C. However at 24[o]C the reduced eclosion rate is partially suppressed, with 89% of flies eclosing (compared to 0.75% when hep^CA.Scer\UAS is expressed alone).

One copy of egr¹ enhances the reduction in eye size seen in both males and females when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^GMR.PF at either 24[o]C or 29[o]C. An enhancement is also seen in females at 18[o]C, but no difference is observed in males.

Expression of puc^Scer\UAS.cMa enhances the reduction in eye size seen in both males and females when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^GMR.PF at any of 18[o]C, 24[o]C or 29[o]C.

One copy of tws^aar-1 partially suppresses the reduction in eye size seen when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^GMR.PF. Eyes are 83% of wild type size in females and 74% in males.

One copy of tws⁶⁰ partially suppresses the reduction in eye size seen when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^GMR.PF. Eyes are of wild type size in females, but only 82% in males.

One copy each of tws^aar-1 and tws⁶⁰ completely suppresses the reduction in eye size seen when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^GMR.PF.

One copy of tws^aar-1 partially suppresses the wing phenotype seen when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^en.PU at 29[o]C. Loss of the posterior part of the wing is seen in 8% of flies, compared to 100% when Zzzz\E4orf4^Scer\UAS.cPa is expressed alone. Many wings exhibit more minor phenotypes and in 25% of flies the wings appear wild type.

One copy of tws⁶⁰ partially suppresses the wing phenotype seen when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^en.PU at 29[o]C. Loss of the posterior part of the wing is seen in 8% of flies, compared to 100% when Zzzz\E4orf4^Scer\UAS.cPa is expressed alone. Many wings exhibit more minor phenotypes and in 11% of flies the wings appear wild type.

One copy of tws^aar-1 partially suppresses the wing disc phenotype seen when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^en.PU at 29[o]C. Only 30% of wing discs contain a cluster of dead cells, compared to 100% when Zzzz\E4orf4^Scer\UAS.cPa is expressed alone.

One copy of tws⁶⁰ partially suppresses the wing disc phenotype seen when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^en.PU at 29[o]C. Only 30% of wing discs contain a cluster of dead cells, compared to 100% when Zzzz\E4orf4^Scer\UAS.cPa is expressed alone.

Expression of tws^GD10742 partially suppresses the wing disc phenotype seen when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^en.PU at 29[o]C. Only 34% of wing discs contain a cluster of dead cells, compared to 100% when Zzzz\E4orf4^Scer\UAS.cPa is expressed alone.

Expression of Src64B^GD12263 partially suppresses the eye phenotypes seen in males when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^GMR.PF at 29[o]C. Eye size is restored to 63% of controls.

Expression of tws^GD10742 partially suppresses the eye phenotypes seen in males when Zzzz\E4orf4^Scer\UAS.cPa is expressed under the control of Scer\GAL4^GMR.PF at 29[o]C. Eye size is restored to 79% of controls.