Gene model reviewed during 5.50
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Jheh1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Jheh1 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Ortholog of B. mori juvenile-hormone-related gene (involved in JH biosynthesis, metabolism or signaling).
Juvenile hormone metabolisms in two lines of adults is studied under normal conditions and after a short period of heat stress.
Heat stress results in delay of oviposition and a decrease in juvenile hormone hydrolysis and fertility, which lasted several days after heat treatment.
The course of changes in the activities of enzymes degrading juvenile hormone (JH) during development is studied and the possible role of the proteins in the regulation of JH titre in critical developmental periods and in reproduction are investigated.
Radiometric assay of JH-hydrolysing activity identified 2 activities: those encoded by Jhe and Jheh. Juvenile hormone hydrolytic activity in larvae is largely due to Jheh.
Abnormally low levels of juvenile hormone are synthesized in ap mutants.
Stage 8 and 9 oocytes transplanted into juvenile hormone (JH) deficient males and females were found to degenerate unless a JH analogue, ZR-515, was applied to the host shortly after implantation. These results suggest that JH is required for the initiation and continuation of vitellogenic uptake and oocyte development.