FlyBase Gene Report: Dmel\kipf

General Information

Symbol

Dmel\kipf

Species

D. melanogaster

Name

kipferl

Annotation Symbol

CG2678

Feature Type

protein_coding_gene

FlyBase ID

FBgn0014931

Gene Model Status

Current

Stock Availability

8 publicly available

Gene Summary

DNA-binding zinc finger protein that recruits chromo domain protein rhino/rhi to specific chromatin regions enriched in H3K9me2/3 histone methylation, mediating piRNA (piwi-interacting RNA) biogenesis (PubMed:36193674). May bind to GC rich DNA sequences including a 5'-GRGGN-3' sequence motif (PubMed:36193674). Nucleates rhi/rhino accumulation and stabilizes its expansion (PubMed:36193674). Involved in piRNA transposon repression, particularly in the female ovary during oogenesis (PubMed:36193674). (UniProt, Q8T053)

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

84E5-84E5

Sequence location

3R:7,913,851..7,916,550 [+]

Recombination map

3-48

RefSeq locus

NT_033777 REGION:7913851..7916550

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (10 terms)

Molecular Function (6 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

enables chromatin DNA binding

inferred from direct assay

(Baumgartner et al., 2022)

enables chromatin-protein adaptor activity

inferred from physical interaction with FLYBASE:rhi; FB:FBgn0004400

(Baumgartner et al., 2022)

enables sequence-specific double-stranded DNA binding

inferred from mutant phenotype

(Baumgartner et al., 2022)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables DNA-binding transcription factor activity

inferred from sequence or structural similarity with UniProtKB:P47043

(Gene Ontology Curators, 2002-)

enables transcription cis-regulatory region binding

inferred from sequence or structural similarity with UniProtKB:P47043

(Gene Ontology Curators, 2002-)

enables zinc ion binding

inferred from sequence or structural similarity with UniProtKB:P47043

(Gene Ontology Curators, 2002-)

inferred from electronic annotation with InterPro:IPR012934

(InterPro Project Members, 2004-)

Biological Process (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in positive regulation of piRNA transcription

inferred from mutant phenotype

(Baumgartner et al., 2022)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in regulation of DNA-templated transcription

inferred from sequence or structural similarity with UniProtKB:P47043

(Gene Ontology Curators, 2002-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in cytosol

inferred from high throughput direct assay

(Lye et al., 2014)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

located_in nucleus

inferred from electronic annotation with InterPro:IPR012934

(InterPro Project Members, 2004-)

inferred from sequence or structural similarity with UniProtKB:P47043

(Gene Ontology Curators, 2002-)

Gene Group (FlyBase)

C2H2 ZINC FINGER TRANSCRIPTION FACTORS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

C2H2 ZINC FINGER TRANSCRIPTION FACTORS -: Zinc finger C2H2 transcription factors are sequence-specific DNA binding proteins that regulate transcription. They possess DNA-binding domains that are formed from repeated Cys₂His₂ zinc finger motifs. (Adapted from PMID:1835093, FBrf0220103 and FBrf0155739).

Protein Function (UniProtKB)

(UniProt, Q8T053)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\kipf for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q8T053)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.49

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

kipf-RA

FBtr0081757

NM_141493

1811

434

kipf-RB

FBtr0304703

NM_001260044

2003

346

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

kipf-PA

FBpp0081254

50.5

434

9.16

FBpp0293246

39.9

346

8.66

D4G7A6

NP_001246973

AFH06292

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Subunit Structure (UniProtKB)

Homodimer; mediated by the ZAD domain (PubMed:36193674). Interacts (via C2H2 type zinc finger 4) with rhi/rhino (via Chromo domain) (PubMed:36193674). Dimerization is required for association with DNA and interaction with rhi/rhino (PubMed:36193674).

(UniProt, Q8T053)

Domain

The ZAD domain is required for dimerization.

Possesses 2 arrays of C2H2 type zinc fingers (PubMed:36193674). The first, consisting of zinc-fingers 1-4, plays a major role in DNA binding, while the second, consisting of zinc fingers 5-7, only has a minor contribution (PubMed:36193674). C2H2 type zinc finger 4 is required and sufficient for interaction with rhi/rhino but is not required for DNA binding (PubMed:36193674).

(UniProt, Q8T053)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q8T053

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\kipf using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CG2678_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.58

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism | ubiquitous

Comment: rapidly degraded

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in cytosol

inferred from high throughput direct assay

(Lye et al., 2014)

Expression Deduced from Reporters

Reporter: PBac{566.P.SVS-1}kipf^CPTI100021

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult brain cell body rind

(Knowles-Barley, 2011.8.24)

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\kipf in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\kipf

View exonic expression by tissue for Dmel\kipf

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0014931

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40937/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0014931

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0014931

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0014931

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG2678

Flygut - An atlas of the Drosophila adult midgut

FBgn0014931

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 17 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 11 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of kipf

Transgenic constructs containing regulatory region of kipf

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 11 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Scer\GAL4^Mef2.PR

kipf^GD4284

viable, with Scer\GAL4^pnr-MD237

kipf^GD4284

Sterility

Allele

female fertile, with Scer\GAL4^nanos.PG

female semi-fertile

kipf^Δ1

female semi-sterile

kipf^fs1

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (34)

Hsap\ZFP30

1 of 14

Yes

Hsap\ZFP69

1 of 14

Yes

Hsap\ZNF7

1 of 14

Yes

Hsap\ZNF12

1 of 14

Yes

Hsap\ZNF25

1 of 14

Yes

Hsap\ZNF33B

1 of 14

Yes

Hsap\ZNF35

1 of 14

Yes

Hsap\ZNF45

1 of 14

Yes

Hsap\ZNF92

1 of 14

Yes

Hsap\ZNF221

1 of 14

Yes

Hsap\ZNF227

1 of 14

Yes

Hsap\ZNF248

1 of 14

Yes

Hsap\ZNF263

1 of 14

Yes

Hsap\ZNF282

1 of 14

Yes

Hsap\ZNF304

1 of 14

Yes

Hsap\ZNF319

1 of 14

Yes

Hsap\ZNF334

1 of 14

Yes

Hsap\ZNF354A

1 of 14

Yes

Hsap\ZNF398

1 of 14

Yes

Hsap\ZNF426

1 of 14

Yes

Hsap\ZNF445

1 of 14

Yes

Hsap\ZNF480

1 of 14

Yes

Hsap\ZNF497

1 of 14

Yes

Hsap\ZNF530

1 of 14

Yes

Hsap\ZNF540

1 of 14

Yes

Hsap\ZNF544

1 of 14

Yes

Hsap\ZNF547

1 of 14

Yes

Hsap\ZNF574

1 of 14

Yes

Hsap\ZNF615

1 of 14

Yes

Hsap\ZNF777

1 of 14

Yes

Hsap\ZNF789

1 of 14

Yes

Hsap\ZNF793

1 of 14

Yes

Hsap\ZNF806

1 of 14

Yes

Hsap\ZNF891

1 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (2)

Rnor\LOC100911196

1 of 14

Yes

Rnor\Zfp105

1 of 14

Yes

Mus musculus (laboratory mouse) (4)

Mmus\Zfp105

1 of 14

Yes

Mmus\Zfp619

1 of 14

Yes

Mmus\Zfp661

1 of 14

Yes

Mmus\Zfp788

1 of 14

Yes

Xenopus tropicalis (Western clawed frog) (3)

Xtro\LOC101733242

1 of 13

Yes

Xtro\LOC116411645

1 of 13

Yes

Xtro\znf628

1 of 13

Yes

Danio rerio (Zebrafish) (6)

Drer\LOC557537

1 of 14

Yes

Drer\LOC108183690

1 of 14

Yes

Drer\si:ch211-198a12.6

1 of 14

Yes

Drer\znf271

1 of 14

Yes

Drer\znf1043

1 of 14

Yes

Drer\znf1046

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (0)

Anopheles gambiae (African malaria mosquito) (19)

Agam\AgaP_AGAP003562

1 of 12

Yes

Agam\AgaP_AGAP004830

1 of 12

Yes

Agam\AgaP_AGAP005135

1 of 12

Yes

Agam\AgaP_AGAP005269

1 of 12

Yes

Agam\AgaP_AGAP005479

1 of 12

Yes

Agam\AgaP_AGAP005482

1 of 12

Yes

Agam\AgaP_AGAP006930

1 of 12

Yes

Agam\AgaP_AGAP007915

1 of 12

Yes

Agam\AgaP_AGAP007956

1 of 12

Yes

Agam\AgaP_AGAP008430

1 of 12

Yes

Agam\AgaP_AGAP008845

1 of 12

Yes

Agam\AgaP_AGAP009068

1 of 12

Yes

Agam\AgaP_AGAP009096

1 of 12

Yes

Agam\AgaP_AGAP009120

1 of 12

Yes

Agam\AgaP_AGAP009130

1 of 12

Yes

Agam\AgaP_AGAP010979

1 of 12

Yes

Agam\AgaP_AGAP011332

1 of 12

Yes

Agam\AgaP_AGAP011544

1 of 12

Yes

Agam\AgaP_AGAP011877

1 of 12

Yes

Arabidopsis thaliana (thale-cress) (1)

Atha\YY1

1 of 13

Yes

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:kipf. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (44)

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

az2

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

idc

1 of 13

Odj

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

wor

1 of 13

zf30C

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

kipf

two hybrid

(Baumgartner et al., 2022)

kipf - CG10979

two hybrid array

(Shokri et al., 2019)

kipf - Hr78

two hybrid array

(Shokri et al., 2019)

kipf - rhi

two hybrid, proximity-dependent biotin identification, Identification by mass spectrometry

(Baumgartner et al., 2022)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Subunit Structure (UniProtKB)

(UniProt, Q8T053 )

Linkouts

BioGRID - A database of protein and genetic interactions.

66123

DroID - A comprehensive database of gene and protein interactions.

FBgn0014931

MIST (protein-protein) - An integrated Molecular Interaction Database

40937

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-48

Cytogenetic map

84E5-84E5

Sequence location

3R:7,913,851..7,916,550 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

84E5-84E5

Limits computationally determined from genome sequence between P{EP}EP3060^EP3060 and P{PZ}grn⁰⁵⁹³⁰

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

84E1-84E2

(Clark, 1997.8.4)

84E-84E

(Clark, 1994)

Experimentally Determined Recombination Data

Location

3-48

(FlyBase, 2016)

3-44.5

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (8)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

85681

w¹¹¹⁸; PBac{WH}kipf^f04685

28630

y¹ v¹; P{TRiP.JF03045}attP2

66457

y¹ w^*; P{kipf-GFP.FPTB}attP40

FlyORF

F003244

M{UAS-kipf.ORF-CC}ZH-21F

F001680

M{UAS-kipf.ORF.3xHA.GW}ZH-86Fb

Kyoto

115359

w¹¹¹⁸; PBac{566.P.SVS-1}kipf^CPTI100021

VDRC

v100902

P{KK106178}VIE-260B

v342942

P{hsFLP}1, y1 w1118; P{HD_CFD02396}attP40/CyO-GFP

Genomic Clones (14)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (9)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD27553

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0014931

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0014931

Antibody Information

Laboratory Generated Antibodies

monoclonal

(Baumgartner et al., 2022)

polyclonal

(Baumgartner et al., 2022)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

New stable cell line derived from OSC : Stable OSC lines expressing internally tagged kipf under control of the Ubi-p63E promoter and an SV40 3'UTR were generated by integration into an RMCE landing site.
(Baumgartner et al., 2022)

Other Comments

The kipf locus harbors an additional 25 amino acid exon, flanked by 109 and 31 nucleotides of intronic sequence up and downstream, respectively, in several laboratory fly strains. Comparison with protein sequences annotated for other Drosophila species confirm the presence of the additional in frame coding sequence, inserted between P347 and K348 of the annotated melanogaster kipf protein. PCR analysis confirmed the absence of the respective DNA sequence from iso1 genomic DNA, which served as the basis of the reference genome.

(Baumgartner et al., 2022)

dsRNA has been made from templates generated with primers directed against this gene. RNAi of CG2678 results in reduced arborization of ddaD and ddaE neurons.

(Parrish et al., 2006)

Transcription unit upstream of that of Prat.

(Clark, 1994)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: anon-84Eb CG2678

(Gong, 1999.11)

Source for identity of: kipf CG2678

(Baumgartner et al., 2022)

Nomenclature comments

Etymology

Named 'kipferl' because mutants show prominent enrichments of 'Rhino' in crescent-shaped structures at the nuclear envelope that are reminiscent of a famous Austrian pastry.

(Baumgartner et al., 2022)

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

(Clark et al., 1998)

CG2678

(Baumgartner et al., 2024, Baumgartner et al., 2022, Shokri et al., 2019, Bischof et al., 2018, Schertel et al., 2015, Czech et al., 2013, Knowles-Barley et al., 2010, Keleman et al., 2009.8.5, Perkins et al., 2009, Parrish et al., 2006, Cho et al., 2005)

Kipf

(Baumgartner et al., 2022)

anon-84Eb

kipf

Name Synonyms

kipferl

(Baumgartner et al., 2024, Baumgartner et al., 2022)

transcript B

(Girdham and Glover, 1991)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 46 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

40937

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q8T053

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q8T053

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q8T053

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0014931

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40937/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0014931

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0014931

FlyMine - An integrated database for Drosophila genomics

FBgn0014931

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG2678

MARRVEL_MODEL - MARRVEL (model organism gene)

40937

Linkouts

BioGRID - A database of protein and genetic interactions.

66123

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0014931

DroID - A comprehensive database of gene and protein interactions.

FBgn0014931

DRSC - Results frm RNAi screens

FBgn0014931

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CG2678_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0014931

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0014931

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG2678

Flygut - An atlas of the Drosophila adult midgut

FBgn0014931

MIST (protein-protein) - An integrated Molecular Interaction Database

40937

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (50)

The following external sites may use different assemblies or annotations than FlyBase.

-0.58

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