FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\FASN2
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General Information
Symbol
Dmel\FASN2
Species
D. melanogaster
Name
Fatty acid synthase 2
Annotation Symbol
CG3524
Feature Type
protein_coding_gene
FlyBase ID
FBgn0042627
Gene Model Status
Current
Stock Availability
15 publicly available
Enzyme Name (EC)
[acyl-carrier-protein] S-acetyltransferase (2.3.1.38)
beta-ketoacyl-[acyl-carrier-protein] synthase I (2.3.1.41)
fatty-acid synthase system (2.3.1.85)
Gene Summary
Fatty acid synthase 2 (FASN2) encodes an enzyme required for the synthesis of branched/methylated long chain fatty acids that are the precursors of methylated cuticular hydrocarbons. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
All Summaries
Also Known As

v(2)k05816, FASNCG3524, mFAS, FASN, FAS

Key Links
Genomic Location
Cytogenetic map
23C5-23C5
Sequence location
Recombination map
2-8
RefSeq locus
NT_033779 REGION:3043947..3056143
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (12 terms)
Molecular Function (8 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
enables fatty acid synthase activity
inferred from mutant phenotype
(Chung et al., 2014)
enables serine hydrolase activity
inferred from high throughput direct assay
(Kumar et al., 2021)
Terms Based on Predictions or Assertions (7 terms)
CV Term
Evidence
References
enables 3-oxoacyl-[acyl-carrier-protein] synthase activity
inferred from electronic annotation with InterPro:IPR018201
(InterPro Project Members, 2004-)
enables [acyl-carrier-protein] S-acetyltransferase activity
inferred from sequence or structural similarity with UniProtKB:P49327
(Gene Ontology Curators, 2002-)
enables acyltransferase activity
inferred from electronic annotation with InterPro:IPR016039
(InterPro Project Members, 2004-)
enables fatty acid synthase activity
inferred from biological aspect of ancestor with PANTHER:PTN000196555
(GO Reference Genome Project, 2011-)
enables oxidoreductase activity
inferred from electronic annotation with InterPro:IPR020843
(InterPro Project Members, 2004-)
enables phosphopantetheine binding
inferred from electronic annotation with InterPro:IPR020806
(InterPro Project Members, 2004-)
enables transferase activity
inferred from electronic annotation with InterPro:IPR001227
(InterPro Project Members, 2004-)
Biological Process (4 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
involved_in cellular response to sucrose stimulus
inferred from direct assay
(Garrido et al., 2015)
involved_in cuticle hydrocarbon biosynthetic process
inferred from mutant phenotype
(Chung et al., 2014)
involved_in methyl-branched fatty acid biosynthetic process
inferred from mutant phenotype
(Chung et al., 2014)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in fatty acid biosynthetic process
inferred from biological aspect of ancestor with PANTHER:PTN000196555
(GO Reference Genome Project, 2011-)
inferred from electronic annotation with InterPro:IPR018201
(InterPro Project Members, 2004-)
Cellular Component (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Catalytic Activity (EC/Rhea)
fatty acid synthase activity
acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H(+) = a long-chain fatty acid + (n+1) CoA + n CO2 + 2n NADP(+) (2.3.1.85)
RHEA 14993: [acyl-carrier-protein] S-acetyltransferase activity
holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA (2.3.1.38)
RHEA 41788: 3-oxoacyl-[acyl-carrier-protein] synthase activity
a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo- [ACP] + CO2 (2.3.1.41)
RHEA 22836:
Summaries
Gene Snapshot
Fatty acid synthase 2 (FASN2) encodes an enzyme required for the synthesis of branched/methylated long chain fatty acids that are the precursors of methylated cuticular hydrocarbons. [Date last reviewed: 2019-03-07]
Gene Group (FlyBase)
FATTY ACID SYNTHASES -
Fatty acid elongation occurs in three cellular compartments: the cytosol, mitochondria, and endoplasmic reticulum (microsomes). In the cytosol, fatty acid elongation is part of de novo lipogenesis and involves acetyl-CoA carboxylase and fatty acid synthase. Fatty acid synthases utilize acetyl CoA and malonyl CoA to elongate fatty acids by two carbons. The primary end product of de novo lipogenesis is palmitate ( 16:0 ) and to a lesser extent myristate ( 14:0 ) and stearate ( 18:0 ). (Adapted from PMID:19763486.)
Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
2

Please see the JBrowse view of Dmel\FASN2 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry M9PB21)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.47

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.56

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FASN2-RA
FBtr0077657
NM_139356
7616
2409
FASN2-RB
FBtr0335386
NM_001273057
8161
2410
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\FASN2 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.21

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult oenocyte
(Chung et al., 2014)
Additional Descriptive Data

FASN2 expression is detected at high levels in carcass but minimally in internal organs by RT-qPCR.

(Garrido et al., 2015)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
day 7 of adulthood -- day 49 of adulthood
adult heart
(Cammarato et al., 2011)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\FASN2 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 14 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of FASN2
Transgenic constructs containing regulatory region of FASN2
Aberrations (Deficiencies and Duplications) ( 3 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (18)
Hsap\FASN
14 of 14
Yes
Yes
Hsap\LINC00614
2 of 14
No
Yes
Hsap\ADH1A
1 of 14
No
No
1  
Hsap\ADH1B
1 of 14
No
No
Hsap\ADH1C
1 of 14
No
No
Hsap\ADH4
1 of 14
No
No
Hsap\ADH6
1 of 14
No
No
1  
Hsap\ADH7
1 of 14
No
No
1  
Hsap\CRYZ
1 of 14
No
No
Hsap\MECR
1 of 14
No
No
4  
Hsap\OXSM
1 of 14
No
No
Hsap\PTGR1
1 of 14
No
No
Hsap\PTGR2
1 of 14
No
No
Hsap\RTN4IP1
1 of 14
No
No
Hsap\TP53I3
1 of 14
No
No
Hsap\VAT1
1 of 14
No
No
1  
Hsap\VAT1L
1 of 14
No
No
Hsap\ZADH2
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (6)
Rnor\Fasn
14 of 14
Yes
Yes
Rnor\Cryz
1 of 14
No
No
Rnor\Tp53i3
1 of 14
No
No
Rnor\Vat1l
1 of 14
No
No
Rnor\Vat1
1 of 14
No
No
Rnor\Zadh2
1 of 14
No
No
Mus musculus (laboratory mouse) (6)
Mmus\Fasn
13 of 14
Yes
Yes
Mmus\Cryzl2
1 of 14
No
No
Mmus\Cryz
1 of 14
No
No
Mmus\Vat1l
1 of 14
No
No
Mmus\Vat1
1 of 14
No
No
Mmus\Zadh2
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (13)
Xtro\fasn
7 of 13
Yes
Yes
Xtro\adh1c
1 of 13
No
No
Xtro\adh5
1 of 13
No
No
Xtro\alx1
1 of 13
No
No
Xtro\mecr
1 of 13
No
No
Xtro\oxsm
1 of 13
No
No
Xtro\ptgr1.2
1 of 13
No
Yes
Xtro\ptgr1.3
1 of 13
No
Yes
Xtro\ptgr2
1 of 13
No
No
Xtro\tp53i3
1 of 13
No
No
Xtro\vat1
1 of 13
No
Yes
Xtro\xiap
1 of 13
No
No
Xtro\zadh2
1 of 13
No
No
Danio rerio (Zebrafish) (8)
Drer\fasn
12 of 14
Yes
Yes
Drer\ccdc57
11 of 14
No
Yes
Drer\fasn2
5 of 14
No
Yes
Drer\cryz
1 of 14
No
No
Drer\pks1
1 of 14
No
Yes
Drer\tp53i3
1 of 14
No
No
Drer\vat1
1 of 14
No
No
Drer\vat1l
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (12)
Cele\fasn-1
14 of 14
Yes
Yes
Cele\F32H2.6
4 of 14
No
Yes
Cele\pks-1
3 of 14
No
Yes
Cele\adh-5
1 of 14
No
No
Cele\D2063.1
1 of 14
No
No
Cele\F10G8.9
1 of 14
No
No
Cele\F39B2.3
1 of 14
No
No
Cele\M106.3
1 of 14
No
No
Cele\mecr-1
1 of 14
No
No
Cele\rad-8
1 of 14
No
No
Cele\Y48A6B.9
1 of 14
No
No
Cele\ZK829.7
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (13)
Agam\AgaP_AGAP009176
8 of 12
Yes
No
Agam\AgaP_AGAP008468
6 of 12
No
No
Agam\AgaP_AGAP001899
5 of 12
No
No
Agam\AgaP_AGAP000287
1 of 12
No
No
Agam\AgaP_AGAP000288
1 of 12
No
No
Agam\AgaP_AGAP000289
1 of 12
No
No
Agam\AgaP_AGAP000414
1 of 12
No
No
Agam\AgaP_AGAP002809
1 of 12
No
No
Agam\AgaP_AGAP006478
1 of 12
No
No
Agam\AgaP_AGAP009224
1 of 12
No
No
Agam\AgaP_AGAP011189
1 of 12
No
No
Agam\AgaP_AGAP011633
1 of 12
No
No
Agam\AgaP_AGAP011834
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (27)
Atha\AT4G21580
3 of 13
Yes
No
Atha\AOR
2 of 13
No
No
Atha\AT5G61510
2 of 13
No
No
Atha\AT5G63620
2 of 13
No
No
Atha\NQR
2 of 13
No
No
Atha\AER
1 of 13
No
No
Atha\AT1G22440
1 of 13
No
No
Atha\AT1G26320
1 of 13
No
No
Atha\AT1G65560
1 of 13
No
No
Atha\AT2G04540
1 of 13
No
No
Atha\AT3G03080
1 of 13
No
No
Atha\AT3G15090
1 of 13
No
No
Atha\AT3G45770
1 of 13
No
No
Atha\AT3G56460
1 of 13
No
No
Atha\AT3G59845
1 of 13
No
No
Atha\AT4G13010
1 of 13
No
No
Atha\AT4G22110
1 of 13
No
No
Atha\AT5G16960
1 of 13
No
No
Atha\AT5G16980
1 of 13
No
No
Atha\AT5G17000
1 of 13
No
No
Atha\AT5G37940
1 of 13
No
No
Atha\AT5G37980
1 of 13
No
No
Atha\AT5G38000
1 of 13
No
No
Atha\AT5G51970
1 of 13
No
No
Atha\FAB1
1 of 13
No
No
Atha\KASI
1 of 13
No
No
Atha\PES1
1 of 13
No
No
Saccharomyces cerevisiae (Brewer's yeast) (9)
Scer\ADH1
1 of 13
Yes
No
Scer\ADH2
1 of 13
Yes
No
Scer\CEM1
1 of 13
Yes
No
Scer\FAS2
1 of 13
Yes
No
Scer\YCR102C
1 of 13
Yes
No
Scer\YLR460C
1 of 13
Yes
No
Scer\YML131W
1 of 13
Yes
No
Scer\YNL134C
1 of 13
Yes
No
Scer\ZTA1
1 of 13
Yes
No
Schizosaccharomyces pombe (Fission yeast) (3)
Spom\SPBC1773.06c
3 of 12
Yes
No
Spom\SPBC16A3.02c
2 of 12
No
No
Spom\zta1
1 of 12
No
No
Escherichia coli (enterobacterium) (1)
Ecol\qorA
1 of 11
Yes
No
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:FASN2. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (6)
FASN1
11 of 13
FASN3
8 of 13
CG12170
2 of 13
Drat
1 of 13
Mecr
1 of 13
Rtn4ip1
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    FASN; fatty acid synthase
    14 of 14
    600212
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        Interaction Browsers
        Summary of Genetic Interactions
        Interaction Browsers
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        External Data
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        External Data
        Linkouts
        KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
        Class of Gene
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        2L
        Recombination map
        2-8
        Cytogenetic map
        23C5-23C5
        Sequence location
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        23C5-23C5
        Limits computationally determined from genome sequence between P{PZ}lilli00632 and P{PZ}toc01361
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        23D1-23D2
        (determined by in situ hybridisation)
        (BDGP Project Members, 2000-)
        23D1-23D2
        (BDGP Project Members, 1994-1999)
        Experimentally Determined Recombination Data
        Location

        2-8

        (FlyBase, 2016)

        2-6.7

        (Comeron et al., 2012)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (15)
        Genomic Clones (22)
        cDNA Clones (8)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequenced
        BDGP DGC clones
        Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          DRSC - Results frm RNAi screens
          Antibody Information
          Laboratory Generated Antibodies
           
          Commercially Available Antibodies
           
          Cell Line Information
          Publicly Available Cell Lines
           
            Other Stable Cell Lines
             
              Other Comments

              Fatty acid synthase (FASN) is encoded by three distinct genes: CG3523, CG3524 and CG17374. Of these, CG3523 is the only FASN gene that is expressed in internal organs, has an essential function (outside of oenocytes), and whose expression affects total triacylglycerol levels in vivo.

              (Garrido et al., 2015)

              This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

              Relationship to Other Genes
              Source for database merge of
              Additional comments
              Nomenclature History
              Source for database identify of

              Source for identity of: FAS-mb v(2)k05816

              (Chung et al., 2014)

              Source for identity of: FASN2 FAS-mb

              (FlyBase, 2009-)
              Nomenclature comments

              There are 3 Fatty acid synthase genes in the Dmel genome (FBrf0219401, FBrf0224329): CG3523 (aka FAS), CG3524 (aka mFAS) and CG17374. The CG3523 gene product is the major, ubiquitously expressed Fatty acid synthase of the three (and the most studied), while CG3524 and CG17374 have lower and more restricted expression (FBrf0219401, FBrf0224329; also see modENCODE RNAseq). The following systematic and informative symbols have therefore been adopted: CG3523 = 'FASN1', CG3524 = 'FASN2' and CG17374 = 'FASN3'. ('FASN', rather than 'FAS', has been used as a shared prefix as this more clearly distinguishes these 'Fatty acid synthase' genes from the unrelated 'faint sausage' gene (symbol 'fas') and 'Fasciclin' genes (symbols 'Fas1', 'Fas2' and 'Fas3'). Furthermore 'FASN' is the HGNC symbol for the human ortholog.)

              (FlyBase, 2009-)
              Etymology
              Synonyms and Secondary IDs (20)
              Reported As
              Symbol Synonym
              CG3524
              (National Institute of Genetics Fly Stocks, 2022-, Wang et al., 2022, Çiçek et al., 2016, Wicker-Thomas et al., 2015, Chung et al., 2014, Parisi et al., 2013, Walls et al., 2013, Cammarato et al., 2011, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Beller et al., 2006)
              DM_7295849
              (Nordling et al., 2002)
              FAS
              (Chung et al., 2014, Parisi et al., 2013)
              FAS-mb
              FAS2
              (Toprak et al., 2020)
              FASCG3524
              (Parvy et al., 2012)
              FASN
              (Akhmetova et al., 2021, Cho et al., 2021)
              FASN2
              (Amartuvshin et al., 2025, Janssens et al., 2025, Sorge et al., 2025, He et al., 2024, Vesala et al., 2024, Delbare et al., 2023, Shi et al., 2023, Eickelberg et al., 2022, Gupta et al., 2022, Li et al., 2022, Wu et al., 2022, Holze et al., 2021, Kumar et al., 2021, Moraes and Montagne, 2021, Hood et al., 2020, Şentürk et al., 2019, Clemson et al., 2018, Mattila and Hietakangas, 2017)
              FASNCG3524
              (Garrido et al., 2015, Wicker-Thomas et al., 2015)
              Fasn2
              (Liu et al., 2023)
              dFASN2
              (François et al., 2023)
              fasn
              (Lourido et al., 2021)
              fasn2
              (Ghosh et al., 2020)
              mFAS
              (Wang et al., 2022, Chung et al., 2014)
              v(2)k05816
              (Fleck et al., 2024, David-Morrison et al., 2016, Kwon et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Friedman et al., 2011, Zhang et al., 2007, Beller et al., 2006, Dionne et al., 2006, Morozova et al., 2006)
              Name Synonyms
              Fatty acid synthase 2
              Fatty acid synthase, methyl-branched specific
              fatty acid synthase 2
              (Lu et al., 2014)
              mbCHC-specific FAS
              (Chung et al., 2014)
              methyl-branched specific FAS
              (Chung et al., 2014)
              v(2)k05816
              (Cammarato et al., 2011)
              Secondary FlyBase IDs
              • FBgn0031502
              Datasets (0)
              Study focus (0)
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              Study result (0)
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              External Crossreferences and Linkouts ( 79 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
              UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
              Other crossreferences
              AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
              DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
              EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
              FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
              FlyMine - An integrated database for Drosophila genomics
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              MARRVEL_MODEL - MARRVEL (model organism gene)
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              DroID - A comprehensive database of gene and protein interactions.
              DRSC - Results frm RNAi screens
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
              FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              Flygut - An atlas of the Drosophila adult midgut
              KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.
              KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
              MIST (protein-protein) - An integrated Molecular Interaction Database
              References (85)