FlyBase Gene Report: Dmel\gskt

General Information

Symbol

Dmel\gskt

Species

D. melanogaster

Name

gasket

Annotation Symbol

CG31003

Feature Type

protein_coding_gene

FlyBase ID

FBgn0046332

Gene Model Status

Current

Stock Availability

8 publicly available

Enzyme Name (EC)

Gene Summary

gasket (gskt) is a retro-transposed glycogen synthase kinase 3 gene, derived from sgg, that is required for male fertility. Like many genes retroposed from the X chromosome, it is highly expressed in the testis. [Date last reviewed: 2018-11-08] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

mojoless, mjl

Key Links

Genomic Location

Cytogenetic map

100C2-100C2

Sequence location

3R:31,372,427..31,374,198 [+]

Recombination map

3-102

RefSeq locus

NT_033777 REGION:31372427..31374198

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (5 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables ATP binding

inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441

(InterPro Project Members, 2004-)

enables protein kinase activity

inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271

(InterPro Project Members, 2004-)

enables protein serine/threonine kinase activity

inferred from sequence or structural similarity with UniProtKB:P49841

(Gene Ontology Curators, 2002-)

Biological Process (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in male gamete generation

inferred from mutant phenotype

(Kalamegham et al., 2007)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN000624299

(GO Reference Genome Project, 2011-)

located_in cytoplasm

inferred from sequence or structural similarity with UniProtKB:P49841

(Gene Ontology Curators, 2002-)

Gene Group (FlyBase)

GLYCOGEN SYNTHASE 3-LIKE KINASES

Protein Family (UniProt)

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. (P83101)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

protein serine/threonine kinase activity

Summaries

Gene Snapshot

Gene Group (FlyBase)

GLYCOGEN SYNTHASE 3-LIKE KINASES -: The Glycogen Synthase kinase 3 family are serine/threonine kinases. There are two isoforms: α and β. GSK-3 enzymes are typically active in unstimulated cells and inhibited by phosphorylation in response to a variety of stimuli. (Adapted from PMID:25552693).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\gskt for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry P83101)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

gskt-RA

FBtr0085784

NM_170547

1772

501

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

gskt-PA

FBpp0085145

56.2

501

4.68

P83101

NP_733426

AAN14270

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Post Translational Modification

Phosphorylation on Tyr-193 is necessary for the activity.

(UniProt, P83101)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

P83101

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\gskt using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

gskt_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

4.94

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

spermatogenesis & adult stage | male

male germline cell

(Kalamegham et al., 2007)

primary gonial cell

(Kalamegham et al., 2007)

adult stage | male & spermatogenesis

male germline stem cell

(Kalamegham et al., 2007)

spermatogonium

(Kalamegham et al., 2007)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

day 5 of adulthood | male -- day 7 of adulthood | male

spermatozoon

(Wasbrough et al., 2010)

Additional Descriptive Data

gskt staining was detected in vas-positive cells of the testis. gskt is expressed in the GSCs, which immediately surround the hub, the gonialblasts, and the developing spermatogonia as evidenced by overlapping staining of anti-

(Kalamegham et al., 2007)

gskt with anti-vas.

(Kalamegham et al., 2007)

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\gskt in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\gskt

View exonic expression by tissue for Dmel\gskt

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

318552/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0046332

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0046332

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0046332

Flygut - An atlas of the Drosophila adult midgut

FBgn0046332

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 9 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of gskt

Transgenic constructs containing regulatory region of gskt

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(3R)Exel6219

(Ryder, 2004.4.26)

Inferred from location ( 1 )

Df(3R)BSC793

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

gskt^GD10127

viable, with Scer\GAL4^Mef2.PR

gskt^GD10127

viable, with Scer\GAL4^pnr-MD237

gskt^GD10127

viable, with Scer\GAL4^tin.CΔ4

gskt^GD10127

Sterility

Allele

male sterile germline-dependent, with Scer\GAL4^{VP16.nanos.UTR}

gskt^RNAi.UAS

Other Phenotypes

Allele

visible, with Scer\GAL4^pnr-MD237

gskt^GD10127

visible, with Scer\GAL4^vg.PU

gskt^UAS.cKa

Phenotype manifest in

Allele

trichogen cell, with Scer\GAL4^pnr-MD237

gskt^GD10127

wing margin, with Scer\GAL4^vg.PU

gskt^UAS.cKa

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (41)

Hsap\GSK3A

9 of 14

Yes

Hsap\GSK3B

9 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (14)

Rnor\Gsk3b

9 of 14

Yes

8 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (15)

Mmus\Gsk3b

9 of 14

Yes

Mmus\Gsk3a

8 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Xenopus tropicalis (Western clawed frog) (18)

Xtro\gsk3b

4 of 13

Yes

3 of 13

3 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\nlk.2

1 of 13

Xtro\nlk

1 of 13

Danio rerio (Zebrafish) (13)

Drer\gsk3ab

9 of 14

Yes

Drer\gsk3ba

9 of 14

Yes

Drer\gsk3bb

9 of 14

Yes

8 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (22)

Cele\gsk-3

11 of 14

Yes

Cele\C44H4.6

4 of 14

Yes

Cele\R03D7.5

3 of 14

Yes

Cele\Y106G6E.1

3 of 14

Yes

Cele\F21F3.2

2 of 14

Yes

Cele\gska-3

2 of 14

Yes

Cele\Y106G6D.4

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (16)

Agam\AgaP_AGAP004443

4 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (49)

Atha\SK32

12 of 13

Yes

Atha\AT3G61160

11 of 13

Yes

Atha\ATSK12

11 of 13

Yes

Atha\BIN2

11 of 13

Yes

Atha\GSK1

11 of 13

Yes

Atha\SK 11

11 of 13

Yes

Atha\SK13

11 of 13

Yes

Atha\SK41

11 of 13

Yes

Atha\SK42

11 of 13

Yes

Atha\SKdZeta

11 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (11)

Scer\MRK1

11 of 13

Yes

Scer\RIM11

11 of 13

Yes

Scer\MCK1

3 of 13

Yes

Scer\YGK3

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (6)

Spom\gsk3

10 of 12

Yes

Spom\gsk31

7 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:gskt. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (16)

sgg

11 of 13

3 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Doa

1 of 13

Hipk

1 of 13

mnb

1 of 13

msn

1 of 13

Obsc

1 of 13

p38a

1 of 13

PKD

1 of 13

Prp4k

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

GSK3A; glycogen synthase kinase 3 alpha

9 of 14

606784

GSK3B; glycogen synthase kinase 3 beta

9 of 14

605004

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

gskt

suppressible

Axn

(Kalamegham et al., 2007)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

sgg

suppressible

gskt

(Kalamegham et al., 2007)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0046332

MIST (genetic) - An integrated Molecular Interaction Database

318552

MIST (protein-protein) - An integrated Molecular Interaction Database

318552

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

P83101

Class of Gene

nuclear_gene

protein_coding_gene

retrogene

(dos Santos, 2014, Pan and Zhang, 2009, Bai et al., 2007, Kalamegham et al., 2007, Dai et al., 2006)

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-102

Cytogenetic map

100C2-100C2

Sequence location

3R:31,372,427..31,374,198 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

100C2-100C2

Limits computationally determined from genome sequence between P{PZ}l(3)rM731^rM731 and P{EP}pygo^EP1076

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

100C1-100C3

(Manning, 2001.10.9)

Experimentally Determined Recombination Data

Location

3-102

(FlyBase, 2016)

3-99.1

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (8)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

82051

y¹ sc^* v¹ sev²¹; P{TKO.GS04494}attP40

64922

y¹ sc^* v¹ sev²¹; P{TRiP.HMC05795}attP2

37883

y¹ w^*; Mi{MIC}gskt^MI04964/TM3, Sb¹ Ser¹

31003R-1

31003R-2

v107429

v25640

w¹¹¹⁸; P{GD10127}v25640

v341057

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD00064}attP40/CyO-GFP

Genomic Clones (20)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (26)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

AT21229

Other clones

DPiM_AT21229

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0046332

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0046332

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Kalamegham et al., 2007)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Source for merge of: gskt BEST:GH16447 NEST:bs22e06

(Rana, 2004.7.8)

Source for merge of: gskt Gsk3b

(FlyBase, 1996-)

Source for merge of: Gsk3b CG31003

(FlyBase, 1996-)

Source for merge of: gskt BcDNA:AT21229

(FlyBase, 1996-)

Additional comments

The gskt gene may have been derived from the Pk34A gene by retroposition.

(Pan and Zhang, 2009)

The gskt gene may have been derived from the sgg gene by retroposition.

(Bai et al., 2007, Kalamegham et al., 2007, Dai et al., 2006)

Source for merge of gskt Gsk3b was sequence comparison ( date:030527 ).

(FlyBase, 1996-)

Source for merge of Gsk3b CG31003 was sequence comparison ( date:030114 ).

(FlyBase, 1996-)

Source for merge of gskt BcDNA:AT21229 was a shared cDNA ( date:030728 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

The name "mojoless" is based on the male sterile loss-of-function phenotype of the gene.

(Kalamegham et al., 2007)

The gene is named "gskt" for "glycogen synthetase kinase three".

(Manning, 2001.10.9)

Synonyms and Secondary IDs (17)

Reported As

Symbol Synonym

BEST:GH16447

BcDNA:AT21229

CG11338

(Kalamegham et al., 2007, Morrison et al., 2000)

CG31003

(Hosono et al., 2015, Keleman et al., 2009.8.5, Pan and Zhang, 2009, Pan and Zhang, 2009, Perkins et al., 2009, Dai et al., 2006, Kalamegham et al., 2006, Rana, 2004.7.8)

CT4237

(Morrison et al., 2000)

Dm Gskt

(Konikoff et al., 2010)

GSK-3b

(Manola et al., 2021)

GSK3b

(Morrison et al., 2000)

Gsk3b

Gskt

(Bai et al., 2007, Bai et al., 2007)

NEST:bs22e06

NGSK

(Kalamegham and Siegfried, 2003)

gskt

(Liang et al., 2021, Ostalé et al., 2021, Huichalaf et al., 2019, Transgenic RNAi Project members, 2017-, dos Santos, 2014, Japanese National Institute of Genetics, 2012.5.21, Nedelsky et al., 2010, Wasbrough et al., 2010, Chau et al., 2009, Bai et al., 2007)

mjl

(Kalamegham and Oliver, 2008, Kalamegham et al., 2007, Kalamegham et al., 2006)

Name Synonyms

GASKET

(Wang et al., 2020)

gasket

(Chau et al., 2009, Kalamegham et al., 2007, Manning, 2001.10.9)

mojoless

(Kalamegham and Oliver, 2008, Bai et al., 2007, Kalamegham et al., 2007, Kalamegham et al., 2006)

Secondary FlyBase IDs

FBgn0043075
FBgn0045206
FBgn0045820
FBgn0051003
FBgn0065002

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 51 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

318552

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

P83101

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

P83101

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

P83101

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

318552/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0046332

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0046332

FlyMine - An integrated database for Drosophila genomics

FBgn0046332

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG31003

MARRVEL_MODEL - MARRVEL (model organism gene)

318552

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0046332

DroID - A comprehensive database of gene and protein interactions.

FBgn0046332

DRSC - Results frm RNAi screens

FBgn0046332

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

gskt_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0046332

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0046332

Flygut - An atlas of the Drosophila adult midgut

FBgn0046332

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0046332

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC032822

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

MIST (genetic) - An integrated Molecular Interaction Database

318552

MIST (protein-protein) - An integrated Molecular Interaction Database

318552

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

P83101

References (58)

The following external sites may use different assemblies or annotations than FlyBase.

4.94

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