FB2020_06, released Dec 22, 2020

Gene: Dmel\snama

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General Information
Symbol
Dmel\snama
Species
D. melanogaster
Name
something that sticks like glue
Annotation Symbol
CG3231
Feature Type
protein_coding_gene
FlyBase ID
FBgn0086129
Gene Model Status
Current
Stock Availability
11 publicly available
Gene Snapshot
something that sticks like glue (snama) encodes a protein required for cell proliferation and survival in the developing eye. It is involved in apoptosis. [Date last reviewed: 2019-06-27]
Other Summaries
Also Known As

l(2)rQ313, BcDNA:LD21643 , mnm, mini-me

Key Links
Genomic Location
Cytogenetic map
60B9-60B9
Sequence location
2R:24,086,604..24,092,014 [+]
Recombination map

2-106

RefSeq locus
NT_033778 REGION:24086604..24092014
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (9 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
enables nucleic acid binding
inferred from electronic annotation with InterPro:IPR001878
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
enables ubiquitin protein ligase activity
inferred from electronic annotation with InterPro:IPR033489
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
enables ubiquitin-protein transferase activity
inferred from sequence or structural similarity with HGNC:9889
(FlyBase Curators, 2008--)
enables zinc ion binding
inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001878, InterPro:IPR014891
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
inferred from sequence model
(Ying et al., 2011)
Biological Process (5 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
involved_in apoptotic process
inferred from mutant phenotype
(Mather et al., 2005)
involved_in cell proliferation involved in compound eye morphogenesis
inferred from mutant phenotype
(Jones et al., 2006)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
involved_in mRNA processing
inferred from electronic annotation with InterPro:IPR033489
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
involved_in protein ubiquitination
inferred from electronic annotation with InterPro:IPR033489
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
involved_in ubiquitin-dependent protein catabolic process
inferred from sequence or structural similarity with HGNC:9889
(FlyBase Curators, 2008--)
Cellular Component (0 terms)
There is no information supporting a Cellular Component term for this gene. (Based on a review of available data on: 2014-04-17 )
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
OTHER RING DOMAIN UBIQUITIN LIGASES -
The RING (Really Interesting New Gene) finger domain co-ordinates two Zn2+ ions via conserved Cys and His residues. Most proteins which contain a RING finger are assumed to be ubiquitin (E3) ligases. The RING finger binds ubiquitin-conjugating enzymes (E2) and promotes direct transfer of ubiquitin to the target protein. (Adapted from FBrf0215242 and PMID:19489725).
Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
2

Please see the JBrowse view of Dmel\snama for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.52

Sequence Ontology: Class of Gene
gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
snama-RA
FBtr0072249
NM_138040
3936
1231
snama-RB
FBtr0307174
NM_001259558
1972
494
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
snama-PA
FBpp0072158
139.0
1231
10.38
NP_611884
AAF47162
snama-PB
FBpp0298003
55.6
494
6.74
NP_001246487
AFH08240
Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\snama using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism
(Fisher et al., 2012)
embryonic stage 7 -- 8
organism | faint | ubiquitous
(Fisher et al., 2012)
embryonic stage 9 -- 10
organism | faint | ubiquitous
(Fisher et al., 2012)
RT-PCR
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage -- adult stage
organism
(Hull et al., 2015)
Additional Descriptive Data

Two snama isoforms are differentially regulated. The shorter shorter isoform, snama-RB is detected in 3-6 hour embryos, while snama-RA is not. Strong snama-RA expression is detected at all other stages tested.

(Hull et al., 2015)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 4 -- 5
organism | ubiquitous
(Hull et al., 2015)
embryonic stage 5
primordial germ cell
(Hull et al., 2015)
ventral furrow
(Hull et al., 2015)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data

snama protein is expressed abundantly and ubiquitously in the blastoderm and reaches lower levels by the cellular blastoderm, at which point, higher concentrations are localized in the ventral furrow and in germ cells. In the blastoderm, snama protein is present in all of the synchronous pre-blastoderm stage nuclei, but later, it is found in the cortical nuclei and absent in the mitotically inactive yolk nuclei. It is present in nurse cell nuclei.

(Hull et al., 2015)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\snama in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 7 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 10 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of snama
Transgenic constructs containing regulatory region of snama
Deletions and Duplications ( 5 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
FlyBase_internaltransgene_features:cell lethal:cell lethal | somatic clone
lethal
lethal | heat sensitive, with Scer\GAL4en-e16E
lethal | recessive
lethal - all die before end of embryonic stage | recessive
lethal - all die before end of pupal stage, with Scer\GAL4pnr-MD237
lethal - all die before end of pupal stage | recessive
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
Sterility
Allele
fertile
Other Phenotypes
Allele
flightless, with Scer\GAL4Mef2.PR
increased cell death
increased cell death | larval stage, with Scer\GAL4en-e16E
increased occurrence of cell division | larval stage, with Scer\GAL4en-e16E
melanotic mass phenotype | adult stage, with Scer\GAL4en-e16E
melanotic mass phenotype | larval stage, with Scer\GAL4en-e16E
neuroanatomy defective, with Scer\GAL4elav-C155
neuroanatomy defective | larval stage
size defective | adult stage, with Scer\GAL4en-e16E
some die during embryonic stage | recessive
some die during pupal stage, with Scer\GAL4pnr-MD237
some die during pupal stage | recessive
visible | somatic clone
Phenotype manifest in
Allele
adult abdomen | dorsal, with Scer\GAL4en-e16E
eye | somatic clone
ganglion mother cell | larval stage
indirect flight muscle, with Scer\GAL4Mef2.PR
larval neuroblast | larval stage
myofibril, with Scer\GAL4Mef2.PR
sarcomere, with Scer\GAL4Mef2.PR
terminal bouton, with Scer\GAL4elav-C155
wing blade posterior compartment, with Scer\GAL4en-e16E
wing disc, with Scer\GAL4en-e16E
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\RBBP6
11 of 15
Yes
Yes
Hsap\AFF4
1 of 15
No
No
1  
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Rbbp6
9 of 15
Yes
Yes
Rattus norvegicus (Norway rat) (2)
Rnor\Rbbp6
8 of 13
Yes
Yes
Rnor\Aff4
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (1)
Xtro\rbbp6
4 of 12
Yes
Yes
Danio rerio (Zebrafish) (110)
Drer\rbbp6
10 of 15
Yes
Yes
Drer\LOC100005013
7 of 15
No
Yes
Drer\LOC100005157
7 of 15
No
Yes
Drer\zgc:174355
7 of 15
No
Yes
Drer\LOC561873
6 of 15
No
Yes
Drer\LOC100004867
6 of 15
No
Yes
Drer\LOC100148590
6 of 15
No
Yes
Drer\si:dkey-23f9.8
6 of 15
No
Yes
Drer\si:dkey-23f9.9
6 of 15
No
Yes
Drer\si:rp71-45g20.4
6 of 15
No
Yes
Drer\zgc:174354
6 of 15
No
Yes
Drer\si:ch211-156l18.6
5 of 15
No
Yes
Drer\si:dkey-23f9.11
5 of 15
No
Yes
Drer\si:dkey-23f9.12
5 of 15
No
Yes
Drer\si:dkey-27d5.4
5 of 15
No
Yes
Drer\si:dkey-27d5.14
5 of 15
No
Yes
Drer\si:rp71-45g20.11
5 of 15
No
Yes
Drer\zgc:77614
5 of 15
No
Yes
Drer\zgc:173948
5 of 15
No
Yes
Drer\zgc:174357
5 of 15
No
Yes
Drer\zgc:174358
5 of 15
No
Yes
Drer\LOC100002202
4 of 15
No
Yes
Drer\LOC100004392
4 of 15
No
Yes
Drer\LOC100006401
4 of 15
No
Yes
Drer\LOC100006815
4 of 15
No
Yes
Drer\LOC100006889
4 of 15
No
Yes
Drer\LOC100007069
4 of 15
No
Yes
Drer\LOC100329917
4 of 15
No
Yes
Drer\LOC100535555
4 of 15
No
Yes
Drer\LOC101882874
4 of 15
No
Yes
Drer\si:busm1-37i06.3
4 of 15
No
Yes
Drer\si:dkey-27d5.5
4 of 15
No
Yes
Drer\si:dkey-27d5.10
4 of 15
No
Yes
Drer\si:rp71-45g20.10
4 of 15
No
Yes
Drer\LOC100007007
3 of 15
No
Yes
Drer\LOC100329755
3 of 15
No
Yes
Drer\LOC100535429
3 of 15
No
Yes
Drer\zgc:91850
3 of 15
No
Yes
Drer\zgc:174353
3 of 15
No
Yes
Drer\LOC573060
2 of 15
No
Yes
Drer\LOC100329825
2 of 15
No
Yes
Drer\LOC100535522
2 of 15
No
Yes
Drer\LOC100536005
2 of 15
No
Yes
Drer\LOC100536964
2 of 15
No
Yes
Drer\LOC101885891
2 of 15
No
Yes
Drer\LOC103911531
2 of 15
No
Yes
Drer\LOC103911535
2 of 15
No
Yes
Drer\LOC103911809
2 of 15
No
Yes
Drer\LOC108179082
2 of 15
No
Yes
Drer\LOC108190973
2 of 15
No
Yes
Drer\LOC108191592
2 of 15
No
Yes
Drer\LOC110440030
2 of 15
No
Yes
Drer\LOC100007049
1 of 15
No
Yes
Drer\LOC100329676
1 of 15
No
Yes
Drer\LOC100333095
1 of 15
No
Yes
Drer\LOC103908682
1 of 15
No
Yes
Drer\LOC103908740
1 of 15
No
Yes
Drer\LOC103909946
1 of 15
No
Yes
Drer\LOC108180010
1 of 15
No
Yes
Drer\LOC108191590
1 of 15
No
Yes
Drer\LOC110438813
1 of 15
No
Yes
Drer\LOC110438814
1 of 15
No
Yes
Drer\LOC110438815
1 of 15
No
Yes
Drer\LOC110438816
1 of 15
No
Yes
Drer\LOC110438817
1 of 15
No
Yes
Drer\LOC110438818
1 of 15
No
Yes
Drer\LOC110438819
1 of 15
No
Yes
Drer\LOC110438820
1 of 15
No
Yes
Drer\LOC110438880
1 of 15
No
Yes
Drer\LOC110438881
1 of 15
No
Yes
Drer\LOC110438882
1 of 15
No
Yes
Drer\LOC110438883
1 of 15
No
Yes
Drer\LOC110438884
1 of 15
No
Yes
Drer\LOC110438885
1 of 15
No
Yes
Drer\LOC110438889
1 of 15
No
Yes
Drer\LOC110438890
1 of 15
No
Yes
Drer\LOC110438891
1 of 15
No
Yes
Drer\LOC110438892
1 of 15
No
Yes
Drer\LOC110438896
1 of 15
No
Yes
Drer\LOC110438897
1 of 15
No
Yes
Drer\LOC110438898
1 of 15
No
Yes
Drer\LOC110438899
1 of 15
No
Yes
Drer\LOC110438900
1 of 15
No
Yes
Drer\LOC110438901
1 of 15
No
Yes
Drer\LOC110438902
1 of 15
No
Yes
Drer\LOC110438903
1 of 15
No
Yes
Drer\LOC110439266
1 of 15
No
Yes
Drer\LOC110439267
1 of 15
No
Yes
Drer\LOC110439268
1 of 15
No
Yes
Drer\LOC110439269
1 of 15
No
Yes
Drer\LOC110439270
1 of 15
No
Yes
Drer\LOC110439271
1 of 15
No
Yes
Drer\LOC110439272
1 of 15
No
Yes
Drer\LOC110439273
1 of 15
No
Yes
Drer\LOC110439274
1 of 15
No
Yes
Drer\LOC110439275
1 of 15
No
Yes
Drer\LOC110439276
1 of 15
No
Yes
Drer\LOC110439277
1 of 15
No
Yes
Drer\LOC110439278
1 of 15
No
Yes
Drer\LOC110439284
1 of 15
No
Yes
Drer\LOC110439285
1 of 15
No
Yes
Drer\LOC110439286
1 of 15
No
Yes
Drer\LOC110439287
1 of 15
No
Yes
Drer\LOC110439288
1 of 15
No
Yes
Drer\LOC110439291
1 of 15
No
Yes
Drer\LOC110439292
1 of 15
No
Yes
Drer\LOC110440092
1 of 15
No
Yes
Drer\LOC110440093
1 of 15
No
Yes
Drer\LOC110440094
1 of 15
No
Yes
Drer\si:dkey-27d5.11
1 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\rbpl-1
12 of 15
Yes
Yes
Arabidopsis thaliana (thale-cress) (2)
Atha\AT5G47430
7 of 9
Yes
Yes
Atha\AT4G17410
4 of 9
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\MPE1
10 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\SPBP8B7.15c
7 of 12
Yes
Yes
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091903E2 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00002288
Drosophila simulans
Dsim\GD27448
Drosophila sechellia
Dsec\GM18306
Drosophila erecta
Dere\GG22940
Drosophila yakuba
Dyak\GE14378
Drosophila ananassae
Dana\GF11371
Drosophila pseudoobscura pseudoobscura
Dpse\GA16823
Drosophila persimilis
Dper\GL11666
Drosophila willistoni
Dwil\GK21919
Drosophila virilis
Dvir\GJ20426
Drosophila mojavensis
Dmoj\GI20676
Drosophila grimshawi
Dgri\GH21725
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915010Q )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17015926
Glossina morsitans
Tsetse fly
Gmor\GMOY002576
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_08210
Mayetiola destructor
Hessian fly
Mdes\Mdes003995
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL002729
Anopheles darlingi
American malaria mosquito
Adar\ADAC005998
Anopheles gambiae
Malaria mosquito
Agam\AGAP011217
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ008053
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W00TL )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA007244
Danaus plexippus
Monarch butterfly
Dple\DPOGS204341-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL005398
Apis florea
Little honeybee
Aflo\2903553684
Apis mellifera
Western honey bee
Amel\GB48828
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP18398
Bombus terrestris
Buff-tailed bumblebee
Bter\15212724
Linepithema humile
Argentine ant
Lhum\LH22745
Linepithema humile
Argentine ant
Lhum\LH22744
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001e51
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG008389
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_07479
Tribolium castaneum
Red flour beetle
Tcas\TC006501
Pediculus humanus
Human body louse
Phum\PHUM515430
Rhodnius prolixus
Kissing bug
Rpro\RPRC007196
Rhodnius prolixus
Kissing bug
Rpro\RPRC007226
Cimex lectularius
Bed bug
Clec\CLEC001222
Cimex lectularius
Bed bug
Clec\CLEC001223
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI003645
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_01658
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X00SC )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR007382
Ixodes scapularis
Black-legged tick
Isca\ISCW023580
Stegodyphus mimosarum
African social velvet spider
Smim\KFM62436.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM62435.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur25g01760
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_309825
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G09Q6 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Hypp_220
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000017248
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000026178
Gallus gallus
Domestic chicken
Ggal\RBBP6
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (0)
No records found.
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    RBBP6; RB binding protein 6, ubiquitin ligase
    11 of 15
    600938
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        esyN Network Diagram
        Show neighbor-neighbor interactions:
        Select Layout:
        Legend:
        Protein
        RNA
        Selected Interactor(s)
        Interactions Browser
        View in Interactions Browser
        Please see the Physical Interaction reports below for full details
        protein-protein
        Physical Interaction
        Assay
        References
        snama - Tet
        experimental knowledge based
        (Guruharsha et al., 2011)
        snama - hrg
        anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
        (Rhee et al., 2014)
        snama - mor
        experimental knowledge based
        (Guruharsha et al., 2011)
        Summary of Genetic Interactions
        esyN Network Diagram
        esyN Network Key:
        Suppression
        Enhancement
        View in Interactions Browser
        Please look at the allele data for full details of the genetic interactions
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        dpp
        suppressible
        snama
        (Jones et al., 2006)
        hh
        enhanceable
        snama
        (Jones et al., 2006)
        N
        suppressible
        snama
        (Jones et al., 2006)
        External Data
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        External Data
        Linkouts
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        2R
        Recombination map

        2-106

        Cytogenetic map
        60B9-60B9
        Sequence location
        2R:24,086,604..24,092,014 [+]
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        60B9-60B9
        Limits computationally determined from genome sequence between P{lacW}Phmk07623&P{lacW}tsrk05633 and P{EP}EP503
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        60B8-60B11
        (determined by in situ hybridisation)
        (Spradling et al., 1999)
        Experimentally Determined Recombination Data
        Location

        2-106

        (FlyBase, 2016)

        2-109.9

        (Comeron et al., 2012)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (11)
        Genomic Clones (17)
         

        Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

        cDNA Clones (32)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequenced
        BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        DRSC - Results frm RNAi screens
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        Antibody Information
        Laboratory Generated Antibodies
         

        polyclonal

        (Hull et al., 2015)
        Commercially Available Antibodies
         
        Other Information
        Relationship to Other Genes
        Source for database identify of

        Source for identity of: BcDNA:LD21643 CG3231

        (Wang, 1999.11)

        Source for identity of: mnm CG3231

        (Jones et al., 2006)

        Source for identity of: mnm l(2)rQ313

        (Jones et al., 2006)
        Source for database merge of

        Source for merge of: l(2)rQ313 CG3231

        (Jones et al., 2006)
        Additional comments
        Other Comments

        mnm appears to be required in proliferative cells, but not in postmitotic cells, in the developing eye.

        (Jones et al., 2006)
        Origin and Etymology
        Discoverer
        Etymology

        Because mutant clones in the developing eye posterior to the morphogenetic furrow differentiate as apparently perfect, yet tiny copies of their wild-type twin spots, the gene is named "mini-me" (Myers M. and M. McCullers, 1999, Austin Powers: The Spy Who Shagged Me. New Line Cinema, Los Angeles).

        (Jones et al., 2006)
        Identification
        External Crossreferences and Linkouts ( 39 )
        Sequence Crossreferences
        NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
        GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
        GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
        RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
        UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
        Other crossreferences
        BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
        Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
        Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
        Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
        Flygut - An atlas of the Drosophila adult midgut
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        InterPro - A database of protein families, domains and functional sites
        KEGG Genes - Molecular building blocks of life in the genomic space.
        modMine - A data warehouse for the modENCODE project
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        DRSC - Results frm RNAi screens
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
        FlyMine - An integrated database for Drosophila genomics
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Synonyms and Secondary IDs (13)
        Datasets (0)
        Study focus (0)
        Experimental Role
        Project
        Project Type
        Title
        References (51)