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Citation
Yang, C.H., Rumpf, S., Xiang, Y., Gordon, M.D., Song, W., Jan, L.Y., Jan, Y.N. (2009). Control of the postmating behavioral switch in Drosophila females by internal sensory neurons.  Neuron 61(4): 519--526.
FlyBase ID
FBrf0207501
Publication Type
Research paper
Abstract

Mating induces changes in the receptivity and egg-laying behavior in Drosophila females, primarily due to a peptide pheromone called sex peptide which is transferred with the sperm into the female reproductive tract during copulation. Whereas sex peptide is generally believed to modulate fruitless-GAL4-expressing neurons in the central nervous system to produce behavioral changes, we found that six to eight sensory neurons on the reproductive tract labeled by both ppk-GAL4 and fruitless-GAL4 can sense sex peptide to control the induction of postmating behaviors. In these sensory neurons, sex peptide appears to act through Pertussis toxin-sensitive G proteins and suppression of protein kinase A activity to reduce synaptic output. Our results uncover a neuronal mechanism by which sex peptide exerts its control over reproductive behaviors in Drosophila females.

PubMed ID
PubMed Central ID
PMC2748846 (PMC) (EuropePMC)
Related Publication(s)
Note

Postcoital finesse.
Clyne and Miesenböck, 2009, Neuron 61(4): 491--493 [FBrf0207481]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Neuron
    Title
    Neuron
    Publication Year
    1988-
    ISBN/ISSN
    0896-6273
    Data From Reference