FlyBase Allele Report: Scer\GAL4[Or67d-GAL4-1]

General Information

Symbol

Scer\GAL4^Or67d-GAL4-1

Species

S. cerevisiae

Name

FlyBase ID

FBal0210953

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

TI{GAL4}Or67d^GAL4-1

Carried in Construct

Also Known As

Or67d-GAL4, Or67d^GAL4

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

ends-in gene targeting

(Kurtovic et al., 2007, Kurtovic et al., 2007)

I-SceI

(Kurtovic et al., 2007)

FLPase

(Kurtovic et al., 2007)

I-CreI

(Kurtovic et al., 2007)

Progenitor genotype

Associated Insertion(s)

TI{GAL4}Or67d^GAL4-1

Cytology

Description

The Or67d open reading frame has been replaced by sequence encoding a GAL4 driver flanked on each side by loxP sites.

(Kurtovic et al., 2007)

Allele components

Component

Use(s)

Inserted element

TI{GAL4}

promoter trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult olfactory receptor neuron Or67d

(Kurtovic et al., 2007)

antennal lobe glomerulus DA1

(Sorkaç et al., 2023)

antennal trichoid sensillum at1

(Ha et al., 2023)

Additional Information

Statement

Reference

Drives expression in adult olfactory receptor neuron Or67d, antennal trichoid sensillum at1, and antennal lobe glomerulus DA1.

(FlyBase Curators, 2017)

Marker for

Reflects expression of

Or67d

(Kurtovic et al., 2007)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior | male, with Bhal\NaChBac^UAS.cNa

(Wang and Anderson, 2010)

abnormal courtship behavior | male | heat sensitive, with Ctet\tetX^{TNT-LC.UAS.cSa}, Scer\FLP1^fru

(Keleman et al., 2012)

abnormal learning | male | heat sensitive, with Ctet\tetX^{TNT-LC.UAS.cSa}, Scer\FLP1^fru

(Keleman et al., 2012)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Hvir\HR13^UAS.cKa, Scer\GAL4^Or67d-GAL4-1 has abnormal smell perception | adult stage phenotype, suppressible by Snmp1¹/Snmp1²

(Gomez-Diaz et al., 2016)

Hvir\HR13^UAS.cKa, Scer\GAL4^Or67d-GAL4-1 has abnormal neurophysiology | adult stage phenotype, suppressible by Snmp1¹/Snmp1²

(Gomez-Diaz et al., 2016)

Phenotype Manifest In

Suppressed by

Statement

Reference

Hvir\HR13^UAS.cKa, Scer\GAL4^Or67d-GAL4-1 has adult olfactory receptor neuron Or67d phenotype, suppressible by Snmp1¹/Snmp1²

(Gomez-Diaz et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Partially rescues

Snmp1^{T274Y.L439Y.UAS}/Scer\GAL4^Or67d-GAL4-1 partially rescues Snmp1¹/Snmp1²

(Gomez-Diaz et al., 2016)

Fails to rescue

Scer\GAL4^Or67d-GAL4-1/Ance-3^UAS.cHa fails to rescue Ance-3³

(Ha et al., 2023)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

604607

w^*; P{UAS-mCD8::GFP.L}LL5; TI{GAL4}Or67d^GAL4-1

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Or67d-GAL4

(Yang et al., 2009)

Or67d^GAL4

(Wu et al., 2022, Gomez-Diaz et al., 2016, Li et al., 2016, Wang and Anderson, 2010, Kurtovic et al., 2007)

Or67d^Gal4

(Kohl et al., 2013)

Scer\GAL4^Or67d-GAL4-1

Name Synonyms

Secondary FlyBase IDs

References (25)

Report Sections

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