Open Close
General Information
Symbol
Ecol\lacZsvp-3
Species
E. coli
Name
FlyBase ID
FBal0041983
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
svp-lacZ, H162, seven up-lacZ, Seven-up-lacZ
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{HZ}svp3
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
neuroblast NB2-3

Comment: late stage 11

neuroblast NB3-3

Comment: late stage 11

neuroblast NB5-4

Comment: late stage 11

neuroblast NB4-4

Comment: late stage 11

neuroblast NB6-4

Comment: late stage 11

neuroblast NB4-2

Comment: late stage 11

distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
neuroblast NB5-1

Comment: late stage 11

neuroblast NB2-4

Comment: late stage 11

neuroblast NB4-3

Comment: late stage 11

neuroblast NB3-4

Comment: late stage 11

neuroblast NB5-5

Comment: late stage 11

neuroblast NB3-1

Comment: late stage 11

neuroblast NB7-3

Comment: late stage 11

Additional Information
Statement
Reference

Seven bilateral pairs of Ecol\lacZsvp-3-positive cells are visible in the embryonic dorsal vessel.

Expression of a svp-lacZ reporter occurs in an increasing number of procephalic neuroblasts through stages 9-11. At the end of neuroblast development in late stage 11 svp reporter expression is detected in 39 neuroblasts per hemisphere.

Reporter expression is observed in two pairs of cardial cells per segment. These correspond to the locations of the ostia.

Expression in procephalic neuroblasts stage 9-11: tritocerebrum - d6, d8, v2; deuterocerebrum - d1, d3, d6-8, d13, v2-8; protocerebrum - ad1, ad7, ad8, ad15, cd2, cd4, cd6, cd8, cd9, cd18, cd21, cv3, cv6, cv7, cv9, pd3, pd9, pd15, pd16, pd18, pd20, pv2

Ecol\lacZsvp-3 expression was usedas a cell marker for intermediate column neuroblasts 3-2, 5-3, and 7-2,but not 4-2 or 6-2. In wg mutant embryos, expression is seen inneuroblast 4-2 in addition to 3-2, 5-3, and 7-2. 6-2 never forms.

Enhancer trap expression is observed in a specified subset of neuroblasts in embryonic stages 8-11. (see also FBrf 51362)

This Ecol\lacZ enhancer trap drivesexpression in photoreceptor cell precursors R1, R3, R4 and R6.

 
Marker for
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (44)