FlyBase Allele Report: Scer\GAL4[34B]

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Allele: Scer\GAL4^34B

General Information

Symbol

Scer\GAL4^34B

Species

S. cerevisiae

Name

FlyBase ID

FBal0052393

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Also Known As

34B-GAL4, 34B, SG-GAL4

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Brand, 1997.6.30, Ingham and Fietz, 1995)

Progenitor genotype

Associated Insertion(s)

Cytology

Description

Allele components

Component

Use(s)

Inserted element

Encoded product / tool

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

No Assay Recorded

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

embryonic/larval posterior midgut

(Brand, 1997.6.30)

embryonic/larval salivary gland

(Brand, 1997.6.30)

third instar larval stage

eye-antennal disc

(Brand, 1997.6.30)

(Brand, 1997.6.30)

(Brand, 1997.6.30, Ingham and Fietz, 1995)

(Brand, 1997.6.30)

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

embryonic/larval salivary gland

(Kester and Nambu, 2011)

embryonic/larval posterior midgut

(Kester and Nambu, 2011)

eye-antennal disc

(Kester and Nambu, 2011)

(Kester and Nambu, 2011)

(Kester and Nambu, 2011)

(Kester and Nambu, 2011)

third instar larval stage

wing pouch | anterior | proximal

(Schürmann et al., 2018)

wing disc | restricted

(Schürmann et al., 2018)

Additional Information

Statement

Reference

Scer\GAL4^34B drives expression in the most proximal part of the anterior wing pouch, in a pattern that does not overlap with that of hh.

(Schürmann et al., 2018)

Drives expression in the embryonic/larval salivary glands, in the most proximal part of the wing disc, and in the embryonic/larval posterior midgut.

(FlyBase Curators, 2017)

Expression in posterior midgut during embryogenesis is unconfirmed.

(Brand, 1997.6.30)

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate | larval stage, with grim^UAS.cUa

(Li et al., 2022)

abnormal developmental rate | larval stage, with rpr^UAS.C

(Li et al., 2022)

decreased body size | adult stage, with grim^UAS.cUa

(Li et al., 2022)

decreased body size | adult stage, with rpr^UAS.C

(Li et al., 2022)

decreased body size | pupal stage, with Sgsf^RNAi.UAS.1

(Li et al., 2022)

decreased body size | pupal stage, with Sgsf^RNAi.UAS.2

(Li et al., 2022)

decreased body size | pupal stage | nutrition conditional, with grim^UAS.cUa

(Li et al., 2022)

decreased body size | pupal stage | nutrition conditional, with rpr^UAS.C

(Li et al., 2022)

decreased body weight | adult stage, with grim^UAS.cUa

(Li et al., 2022)

decreased cell size | larval stage, with rpr^UAS.C

(Li et al., 2022)

decreased size | adult stage, with grim^UAS.cUa

(Li et al., 2022)

decreased size | larval stage, with grim^UAS.cUa

(Li et al., 2022)

decreased size | larval stage, with rpr^UAS.C

(Li et al., 2022)

increased body size | pupal stage, with Sgsf^UAS.Tag:HA

(Li et al., 2022)

increased cell death, with Diap1^RNAi.UAS

(Choi et al., 2006)

increased cell death, with Diap1^UAS.cHa

(Choi et al., 2006)

increased size | larval stage, with Sgsf^UAS.Tag:HA

(Li et al., 2022)

lethal, with dy^RNAi.UAS.cAa

(Akten et al., 2002)

lethal, with E2f1^UAS.cNa

(Morris et al., 2006)

lethal, with Hsap\CDKN1A^UAS.cHa

(Morris et al., 2006)

lethal, with rpr^UAS.cZa

(Morris et al., 2006)

viable, with Cyp28d1^GD905

(Highfill et al., 2017)

viable, with Cyp28d1^HMJ21210

(Highfill et al., 2017)

viable, with Cyp28d1^KK106685

(Highfill et al., 2017)

viable, with Cyp28d2^GD904

(Highfill et al., 2017)

viable, with Cyp28d2^KK103284

(Highfill et al., 2017)

viable, with Sec10^RNAi.UAS

(Andrews et al., 2002)

viable, with Ugt35C1^GD2908

(Highfill et al., 2017)

viable, with Ugt35C1^KK106033

(Highfill et al., 2017)

visible, with Drer\shha^UAS.cIa

(Haines and van Den Heuvel, 2000)

Phenotype Manifest In

chemosensory ventral triple row bristle, with Drer\shha^UAS.cIa

(Ingham and Fietz, 1995)

dorsal row of triple row of wing sensilla, with Drer\shha^UAS.cIa

(Ingham and Fietz, 1995)

embryonic/larval salivary gland | larval stage, with grim^UAS.cUa

(Li et al., 2022)

embryonic/larval salivary gland | larval stage, with rpr^UAS.C

(Li et al., 2022)

embryonic/larval salivary gland | larval stage, with Sgsf^UAS.Tag:HA

(Li et al., 2022)

larval brain | larval stage, with grim^UAS.cUa

(Li et al., 2022)

larval brain | larval stage, with rpr^UAS.C

(Li et al., 2022)

larval brain | larval stage, with Sgsf^UAS.Tag:HA

(Li et al., 2022)

larval fat cell, with grim^UAS.cUa

(Li et al., 2022)

larval fat cell, with rpr^UAS.C

(Li et al., 2022)

larval fat cell, with Sgsf^UAS.Tag:HA

(Li et al., 2022)

mechanosensory ventral triple row bristle, with Drer\shha^UAS.cIa

(Ingham and Fietz, 1995)

medial row of triple row of wing sensilla, with Drer\shha^UAS.cIa

(Ingham and Fietz, 1995)

mitochondrion, with Trpm^GD4541

(Georgiev et al., 2010)

polytene chromosome | third instar larval stage, with BEAF-32^{BID.UAS.Tag:HA,Tag:NLS(SV40-largeT)}

(Gilbert et al., 2006)

salivary gland | pupal stage, with BacA\p35^UAS.cHa

(Leulier et al., 2006)

salivary gland | pupal stage, with Dark^RNAi.UAS.cLa

(Leulier et al., 2006)

salivary gland | pupal stage, with Drice^RNAi.UAS.cLb

(Leulier et al., 2006)

salivary gland | pupal stage, with Dronc^RNAi.UAS.cLa

(Leulier et al., 2006)

salivary gland | pupal stage, with Strica^RNAi.UAS.cLa

(Leulier et al., 2006)

ventral row of triple row of wing sensilla, with Drer\shha^UAS.cIa

(Ingham and Fietz, 1995)

wing, with Drer\shha^UAS.cIa

(Haines and van Den Heuvel, 2000)

wing, with dy^RNAi.UAS.cAa

(Akten et al., 2002)

wing, with grim^UAS.cUa

(Li et al., 2022)

wing | anterior | proximal, with hh^UAS.cIa

(Ingham and Fietz, 1995)

wing blade anterior compartment, with hh^UAS.cIa

(Ingham and Fietz, 1995)

wing disc, with grim^UAS.cUa

(Li et al., 2022)

wing disc, with rpr^UAS.C

(Li et al., 2022)

wing disc, with Sgsf^UAS.Tag:HA

(Li et al., 2022)

wing vein, with Delta^DN.UAS

(Shalaby et al., 2009)

Detailed Description

Statement

Reference

Genetic ablation of salivary glands by the expression of rpr^UAS.C or grim^UAS.cUa under the control of the salivary gland driver Scer\GAL4^34B results in delayed larval-to-pupal transition, small pupae, small larval wing discs, small larval fat body cells and small larval brains - as well as residual larval salivary glands. Ablation by grim^UAS.cUa also results in decreased adult body size and weight, and decreased wing size. The decreased pupal body size is not observed under a high-protein diet.

(Li et al., 2022)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Delta^DN.UAS, Scer\GAL4^34B has wing vein phenotype, enhanceable by kst[+]/kst^d11183, Scer\GAL4^34B

(Shalaby et al., 2009)

Suppressed by

Statement

Reference

Delta^DN.UAS, Scer\GAL4^34B has wing vein phenotype, suppressible | partially by Amun[+]/Amun^d03329, Scer\GAL4^34B

(Shalaby et al., 2009)

Enhancer of

Statement

Reference

kst[+]/kst^d11183, Scer\GAL4^34B is an enhancer of wing vein phenotype of Delta^DN.UAS, Scer\GAL4^34B

(Shalaby et al., 2009)

Suppressor of

Statement

Reference

Amun[+]/Amun^d03329, Scer\GAL4^34B is a suppressor | partially of wing vein phenotype of Delta^DN.UAS, Scer\GAL4^34B

(Shalaby et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^34B/Sgsf^UAS.Tag:HA rescues Sgsf^KO

(Li et al., 2022)

Scer\GAL4^34B/Diap1^UAS.cHa rescues Diap1^RNAi.UAS

(Choi et al., 2006)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

1967

y¹ w^*; P{GawB}34B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^34B

Scer\GAL4^34B

Name Synonyms

Secondary FlyBase IDs

References (23)

Report Sections