A BruceE81 or BruceE23 heterozygous background does not affect the pigment cell death phenotype caused by the overexpression of Ncpro.Scer\UAS in the developing eye under the control of Scer\GAL4GMR.PF.
Either a BruceE81/+ or BruceE23/+ heterozygous background has no effect on the eye ablation phenotype found upon co-expression of ArkScer\UAS.T:Zzzz\His6,T:Hsap\MYC and Ncpro.Scer\UAS in the developing eye under the control of Scer\GAL4GMR.PF.
Co-expression of Ncpro.Scer\UAS in ykiScer\UAS.cHa-expressing cells (both under the control of Scer\GAL4GMR.PF) results in a decrease in cell division and an increase in apoptosis, compared to expression of ykiScer\UAS.cHa alone.
Co-expression of ArkScer\UAS.T:Zzzz\His6,T:Hsap\MYC, Ncpro.Scer\UAS and hpoScer\UAS.cUa in the developing eye, under the control of Scer\GAL4GMR.PF induces massive apoptosis in the eye-antennal disc and adult. This phenotype appears stronger than controls as both photoreceptor and pigment cells are eventually eliminated in animals co-expressing hpoScer\UAS.cUa.
Co-expression of Hsp60DdsRNA.Sym.Scer\UAS suppresses the eye phenotypes caused by both weakly and strongly expressing Ncpro.Scer\UAS lines driven by Scer\GAL4GMR.PF, and all these animals eclose with normal head size.
The expression of Droncpro.Scer\UAS under the control of Scer\GAL4nos.PU rescues both the significant proportion of hyperplastic adult testes and the increased necrosis at the apical tip of testes observed in DroncI29/DroncL32 transheterozygotes.