FlyBase Allele Report: Scer\GAL4[Antp-10]

General Information

Symbol

Scer\GAL4^Antp-10

Species

S. cerevisiae

Name

FlyBase ID

FBal0155892

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}Antp-10

Carried in Construct

Also Known As

Antp-gal4, Antennapedia-Gal4

Allele class

Mutagen

gene conversion

Nature of the Allele

Allele class

Mutagen

gene conversion

(Emerald and Cohen, 2004)

Progenitor genotype

P{AntpP1-lacZ}8.4

(Emerald and Cohen, 2004)

Associated Insertion(s)

P{GawB}Antp-10

Cytology

Description

The P{AntpP1-lacZ} sequences present in P{AntpP1-lacZ}8.4 have been replaced by P{GawB} sequences (using P{GawB}Bx^MS1096 as a donor) by gene conversion.

(Emerald and Cohen, 2004)

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 16 -- 17

posterior signaling center of lymph gland primary lobe

(Benmimoun et al., 2015)

larval cardial cell | subset

Comment: associated with posterior signaling center of lymph gland primary lobe

(Benmimoun et al., 2015)

larval stage

posterior signaling center of lymph gland primary lobe

(Sinenko et al., 2011)

first instar larval stage -- third instar larval stage

posterior signaling center of lymph gland primary lobe

(Sinenko et al., 2009)

third instar larval stage

leg disc | restricted

(Emerald and Cohen, 2004)

Additional Information

Statement

Reference

Scer\GAL4^Antp-10 is expressed in the primary lobes of the posterior signaling center of the lymph gland, as well as in some cardiomyocytes present between the primary lobes.

(Benmimoun et al., 2015)

ScerGAL4^Antp-10 drives expression in the posterior signalling center of the primary lobe of the lymph gland.

(Sinenko et al., 2011)

Marker for

posterior signaling center of lymph gland primary lobe

(Sinenko et al., 2009)

Reflects expression of

Antp

(Sinenko et al., 2011, Sinenko et al., 2009)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell number | larval stage, with rpr^UAS.C

(Rodrigues et al., 2021)

decreased cell number | third instar larval stage | conditional, with Cat^UAS.cAa

(Sinenko et al., 2011)

decreased cell number | third instar larval stage | conditional, with Sod2^UAS.cMa

(Sinenko et al., 2011)

decreased occurrence of cell division | larval stage, with Antp^UAS.cMb

(Mandal et al., 2007)

increased cell number | third instar larval stage, with COX5A^RNAi.cMa

(Sinenko et al., 2011)

increased cell number | third instar larval stage, with Marf^GD11094

(Sinenko et al., 2011)

increased cell number | third instar larval stage, with Marf^KK105681

(Sinenko et al., 2011)

increased cell number | third instar larval stage, with ND-75^GD6309

(Sinenko et al., 2011)

increased cell number | third instar larval stage, with ND-75^KK108222

(Sinenko et al., 2011)

increased cell number | third instar larval stage, with ND-PDSW^GD12532

(Sinenko et al., 2011)

increased cell number | third instar larval stage, with ND-PDSW^KK108420

(Sinenko et al., 2011)

Phenotype Manifest In

embryonic/larval lymph gland, with Antp^UAS.cMb

(Mandal et al., 2007)

embryonic/larval lymph gland | larval stage, with rpr^UAS.C

(Rodrigues et al., 2021)

embryonic/larval lymph gland | third instar larval stage, with fz2^{ECD.GPI.UAS.Tag:MYC}

(Sinenko et al., 2009)

embryonic/larval lymph gland | third instar larval stage, with wg^{UAS.cHa.Tag:HA}

(Sinenko et al., 2009)

lamellocyte | decreased number | larval stage, with rpr^UAS.C

(Rodrigues et al., 2021)

lamellocyte | larval stage, with ND-75^GD6309

(Sinenko et al., 2011)

lamellocyte | larval stage | conditional, with spi^NIG.10334R

(Sinenko et al., 2011)

lamellocyte | third instar larval stage, with COX5A^RNAi.cMa

(Sinenko et al., 2011)

lamellocyte | third instar larval stage, with Marf^GD11094

(Sinenko et al., 2011)

lamellocyte | third instar larval stage, with Marf^KK105681

(Sinenko et al., 2011)

lamellocyte | third instar larval stage, with ND-75^GD6309

(Sinenko et al., 2011)

lamellocyte | third instar larval stage, with ND-75^KK108222

(Sinenko et al., 2011)

lamellocyte | third instar larval stage, with ND-PDSW^GD12532

(Sinenko et al., 2011)

lamellocyte | third instar larval stage, with ND-PDSW^KK108420

(Sinenko et al., 2011)

lamellocyte | third instar larval stage | conditional, with Cat^UAS.cAa

(Sinenko et al., 2011)

lamellocyte | third instar larval stage | conditional, with Sod2^UAS.cMa

(Sinenko et al., 2011)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

ND-75^GD6309, Scer\GAL4^Antp-10 has increased cell number | third instar larval stage phenotype, non-suppressible by upd2^NIG.5988R, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^GD6309, Scer\GAL4^Antp-10 has increased cell number | third instar larval stage phenotype, non-suppressible by upd1^NIG.5993R, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^GD6309, Scer\GAL4^Antp-10 has increased cell number | third instar larval stage phenotype, non-suppressible by upd3^RNAi.UAS, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^GD6309, Scer\GAL4^Antp-10 has increased cell number | third instar larval stage phenotype, non-suppressible by egr^KK103432, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^GD6309, Scer\GAL4^Antp-10 has increased cell number | third instar larval stage phenotype, non-suppressible by egr^GD12658, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^KK108222, Scer\GAL4^Antp-10 has increased cell number | third instar larval stage phenotype, non-suppressible by bsk^DN.UAS, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^KK108222, Scer\GAL4^Antp-10 has increased cell number | third instar larval stage phenotype, non-suppressible by msn^UAS.cSa, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

NOT Suppressor of

Statement

Reference

upd2^NIG.5988R, Scer\GAL4^Antp-10 is a non-suppressor of increased cell number | third instar larval stage phenotype of ND-75^GD6309, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

upd1^NIG.5993R, Scer\GAL4^Antp-10 is a non-suppressor of increased cell number | third instar larval stage phenotype of ND-75^GD6309, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

upd3^RNAi.UAS, Scer\GAL4^Antp-10 is a non-suppressor of increased cell number | third instar larval stage phenotype of ND-75^GD6309, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

egr^KK103432, Scer\GAL4^Antp-10 is a non-suppressor of increased cell number | third instar larval stage phenotype of ND-75^GD6309, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

egr^GD12658, Scer\GAL4^Antp-10 is a non-suppressor of increased cell number | third instar larval stage phenotype of ND-75^GD6309, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

bsk^DN.UAS, Scer\GAL4^Antp-10 is a non-suppressor of increased cell number | third instar larval stage phenotype of ND-75^KK108222, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

msn^UAS.cSa, Scer\GAL4^Antp-10 is a non-suppressor of increased cell number | third instar larval stage phenotype of ND-75^KK108222, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

Phenotype Manifest In

Suppressed by

Statement

Reference

ND-75^GD6309, Scer\GAL4^Antp-10 has lamellocyte | larval stage phenotype, suppressible by Sod2^UAS.cMa, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

NOT suppressed by

Statement

Reference

ND-75^GD6309, Scer\GAL4^Antp-10 has lamellocyte | third instar larval stage phenotype, non-suppressible by upd2^NIG.5988R, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^GD6309, Scer\GAL4^Antp-10 has lamellocyte | third instar larval stage phenotype, non-suppressible by upd1^NIG.5993R, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^KK108222, Scer\GAL4^Antp-10 has lamellocyte | third instar larval stage phenotype, non-suppressible by bsk^DN.UAS, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^KK108222, Scer\GAL4^Antp-10 has lamellocyte | third instar larval stage phenotype, non-suppressible by msn^UAS.cSa, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^GD6309, Scer\GAL4^Antp-10 has lamellocyte | third instar larval stage phenotype, non-suppressible by upd3^RNAi.UAS, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^GD6309, Scer\GAL4^Antp-10 has lamellocyte | third instar larval stage phenotype, non-suppressible by egr^KK103432, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

ND-75^GD6309, Scer\GAL4^Antp-10 has lamellocyte | third instar larval stage phenotype, non-suppressible by egr^GD12658, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

Suppressor of

Statement

Reference

Sod2^UAS.cMa, Scer\GAL4^Antp-10 is a suppressor of lamellocyte | larval stage phenotype of ND-75^GD6309, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

Scer\GAL4^Antp-10/spi^NIG.10334R is a suppressor of lamellocyte | larval stage phenotype of ND-75^GD6309, Scer\GAL4^Ugt36A1.PK

(Sinenko et al., 2011)

NOT Suppressor of

Statement

Reference

upd2^NIG.5988R, Scer\GAL4^Antp-10 is a non-suppressor of lamellocyte | third instar larval stage phenotype of ND-75^GD6309, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

bsk^DN.UAS, Scer\GAL4^Antp-10 is a non-suppressor of lamellocyte | third instar larval stage phenotype of ND-75^KK108222, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

msn^UAS.cSa, Scer\GAL4^Antp-10 is a non-suppressor of lamellocyte | third instar larval stage phenotype of ND-75^KK108222, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

upd1^NIG.5993R, Scer\GAL4^Antp-10 is a non-suppressor of lamellocyte | third instar larval stage phenotype of ND-75^GD6309, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

upd3^RNAi.UAS, Scer\GAL4^Antp-10 is a non-suppressor of lamellocyte | third instar larval stage phenotype of ND-75^GD6309, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

egr^KK103432, Scer\GAL4^Antp-10 is a non-suppressor of lamellocyte | third instar larval stage phenotype of ND-75^GD6309, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

egr^GD12658, Scer\GAL4^Antp-10 is a non-suppressor of lamellocyte | third instar larval stage phenotype of ND-75^GD6309, Scer\GAL4^Antp-10

(Sinenko et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^Antp-10

Name Synonyms

Secondary FlyBase IDs

References (18)

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