FlyBase Gene Report: Dmel\fzo

General Information

Symbol

Dmel\fzo

Species

D. melanogaster

Name

fuzzy onions

Annotation Symbol

CG4568

Feature Type

protein_coding_gene

FlyBase ID

FBgn0011596

Gene Model Status

Current

Stock Availability

4 publicly available

Gene Summary

fuzzy onions (fzo) encodes an evolutionarily conserved transmembrane Dynamin-type GTPase and founder member of the mitofusin class of proteins. It is required for proper fusion of mitochondria during spermatid differentiation to form the Nebenkern mitochondrial formation. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

94E6-94E6

Sequence location

3R:23,201,644..23,204,034 [-]

Recombination map

3-78

RefSeq locus

NT_033777 REGION:23201644..23204034

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (11 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables GTP binding

inferred from electronic annotation with InterPro:IPR030381

(InterPro Project Members, 2004-)

enables GTPase activity

inferred from electronic annotation with InterPro:IPR006884, InterPro:IPR027094

(InterPro Project Members, 2004-)

inferred from sequence or structural similarity with UniProtKB:Q8IWA4

(Gene Ontology Curators, 2002-)

inferred from biological aspect of ancestor with PANTHER:PTN002573358

(GO Reference Genome Project, 2011-)

inferred from sequence or structural similarity

(Hales and Fuller, 1997)

Biological Process (6 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

involved_in mitochondrial fusion

inferred from mutant phenotype

(Hales and Fuller, 1997)

involved_in Nebenkern assembly

inferred from mutant phenotype

(Hales and Fuller, 1997)

involved_in positive regulation of mitochondrial fusion

inferred from mutant phenotype

(Deng et al., 2008)

involved_in sperm mitochondrion organization

inferred from mutant phenotype

(Deng et al., 2008)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in mitochondrial fusion

inferred from biological aspect of ancestor with PANTHER:PTN002573358

(GO Reference Genome Project, 2011-)

inferred from electronic annotation with InterPro:IPR006884

(InterPro Project Members, 2004-)

traceable author statement

(Mozdy and Shaw, 2003)

involved_in mitochondrion localization

inferred from biological aspect of ancestor with PANTHER:PTN002573358

(GO Reference Genome Project, 2011-)

involved_in spermatogenesis

traceable author statement

(Mozdy and Shaw, 2003)

Cellular Component (3 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in mitochondrial envelope

inferred from direct assay

(Hales and Fuller, 1997)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

located_in membrane

traceable author statement

(Mozdy and Shaw, 2003)

inferred from electronic annotation with InterPro:IPR006884

(InterPro Project Members, 2004-)

is_active_in mitochondrial outer membrane

inferred from biological aspect of ancestor with PANTHER:PTN002573358

(GO Reference Genome Project, 2011-)

located_in mitochondrial outer membrane

inferred from electronic annotation with InterPro:IPR006884

(InterPro Project Members, 2004-)

inferred from experiment

(Hales and Fuller, 1997)

Gene Group (FlyBase)

DYNAMIN-LIKE GTPASES

Protein Family (UniProt)

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily. (O18412)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

GTPase activity
RHEA 19669:

Summaries

Gene Snapshot

Gene Group (FlyBase)

DYNAMIN-LIKE GTPASES -: The Dynamin-like GTPases are a family of GTPases that undergo nucleotide-dependent dimerization and dimer-dependent GTP hydrolysis. They are implicated in membrane remodelling and endocytic membrane fission events. (Adapted from PMID:22233676).

Protein Function (UniProtKB)

Essential transmembrane GTPase, which mediates mitochondrial fusion during spermatogenesis (PubMed:18799731, PubMed:9230308). In early spermatocytes, fusion of mitochondria give rise to two organelles named Nebenkern and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission (PubMed:18799731, PubMed:9230308). Essential for fertility (PubMed:9230308).

(UniProt, O18412)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\fzo for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry O18412)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

fzo-RA

FBtr0084399

NM_170060

2391

718

Additional Transcript Data and Comments

Reported size (kB)

2.399 (longest cDNA)

(Hales and Fuller, 1997)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

fzo-PA

FBpp0083791

81.6

718

6.06

O18412

NP_732840

AAF56110

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

718 (aa)

(Hales and Fuller, 1997)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

O18412

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\fzo using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

fzo_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

2.11

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

hypopharynx proper primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic hypopharynx

(Fisher et al., 2012)

adult stage | male

testis | restricted

(Perezgasga et al., 2004)

spermatogenesis & adult stage | male

primary spermatocyte

(Hwa et al., 2002)

spermatocyte

(Lu et al., 2013)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | male

organism

Comment: not observed in adult females or embryos

(Hwa et al., 2002)

Additional Descriptive Data

fzo is observed in primary spermatocytes, but is absent in early spermatid.

(Hwa et al., 2002)

Marker for

testis

(Perezgasga et al., 2004)

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

spermatogenesis & adult stage

spermatid

(Hales and Fuller, 1997)

Nebenkern

(Hales and Fuller, 1997)

inferred from author statements

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | male & spermatogenesis

coalescence stage spermatid

(Hwa et al., 2002)

agglomeration stage spermatid

(Hwa et al., 2002)

Additional Descriptive Data

fzo protein is detected at the end of male meiosis and in early stage spermatids when mitochondrial fusion occurs.

(Hwa et al., 2002)

fzo protein is associated with mitochondria in spermatids during a narrow developmental window. It is first detected in the last stages of meiosis II. In postmeiotic haploid spermatids, it is associated with aggregating mitochondria and is present at the highest levels on onion stage Nebenkerns. It is detected at lower levels on early elongation stage mitochondria.

(Hales and Fuller, 1997)

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in mitochondrial envelope

inferred from direct assay

(Hales and Fuller, 1997)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\fzo in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\fzo

View exonic expression by tissue for Dmel\fzo

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0011596

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

42745/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0011596

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0011596

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0011596

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

Flygut - An atlas of the Drosophila adult midgut

FBgn0011596

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 4 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of fzo

Transgenic constructs containing regulatory region of fzo

Aberrations (Deficiencies and Duplications) ( 5 )

Inferred from experimentation ( 5 )

Gene disrupted in

Df(3R)Exel6274

(Ryder, 2004.4.26)

Df(3R)Exel6280

(Ryder, 2004.4.26)

Df(3R)M95A

(Hales and Fuller, 1997)

Df(3R)P2O

(Hales and Fuller, 1997)

Gene not disrupted in

Df(3R)EB6

(Hales and Fuller, 1997)

Inferred from location ( 8 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

fzo^GD196

viable, with Scer\GAL4^Mef2.PR

fzo^GD196

viable, with Scer\GAL4^pnr-MD237

fzo^GD196

Sterility

Allele

female fertile

male sterile | recessive

Phenotype manifest in

Allele

Nebenkern

Nebenkern (with Df(3R)P2O)

fzo¹

Nebenkern | germline clone

fzo¹

Nebenkern derivative (with Df(3R)P2O)

fzo¹

onion stage spermatid & mitochondrion

spermatid (with fzo¹)

fzo²

spermatid (with fzo²)

fzo¹

spermatid & mitochondrion

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (9)

Hsap\MFN1

6 of 14

Yes

Hsap\MFN2

6 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (5)

Rnor\Mfn1

6 of 14

Yes

Rnor\Mfn2

6 of 14

Yes

Rnor\Dnm3

1 of 14

Rnor\Mx1

1 of 14

Rnor\Mx2

1 of 14

Mus musculus (laboratory mouse) (7)

Mmus\Mfn2

6 of 14

Yes

5 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (4)

Xtro\mfn1

3 of 13

Yes

Xtro\mfn2

3 of 13

Yes

Xtro\drp2

1 of 13

Xtro\skp2

1 of 13

Danio rerio (Zebrafish) (13)

Drer\mfn2

6 of 14

Yes

5 of 14

3 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (2)

Cele\fzo-1

7 of 14

Yes

Cele\eat-3

1 of 14

Anopheles gambiae (African malaria mosquito) (3)

Agam\AgaP_AGAP001802

5 of 12

Yes

Agam\AgaP_AGAP008896

1 of 12

Agam\AgaP_AGAP011286

1 of 12

Arabidopsis thaliana (thale-cress) (14)

Atha\FZL

3 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (4)

Scer\FZO1

6 of 13

Yes

Scer\DNM1

1 of 13

Scer\MGM1

1 of 13

Scer\VPS1

1 of 13

Schizosaccharomyces pombe (Fission yeast) (4)

Spom\fzo1

8 of 12

Yes

Spom\dnm1

1 of 12

Spom\msp1

1 of 12

Spom\vps1

1 of 12

Escherichia coli (enterobacterium) (1)

Ecol\rdcA

1 of 11

Yes

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:fzo. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (4)

Marf

7 of 13

Drp1

1 of 13

Opa1

1 of 13

shi

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 4 )

Human Ortholog

Disease

Evidence

References

MFN2; mitofusin 2

model of multiple symmetric lipomatosis

IEA

(FlyBase, 2019-)

model of Charcot-Marie-Tooth disease type 6

IEA

(FlyBase, 2019-)

model of Charcot-Marie-Tooth disease type 2A2A

IEA

(FlyBase, 2019-)

model of Charcot-Marie-Tooth disease type 2A2B

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

6 of 14

6 of 14

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

67689

DroID - A comprehensive database of gene and protein interactions.

FBgn0011596

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-78

Cytogenetic map

94E6-94E6

Sequence location

3R:23,201,644..23,204,034 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

94E6-94E6

Limits computationally determined from genome sequence between P{PZ}cnc⁰³⁹²¹ and P{PZ}l(3)06906⁰⁶⁹⁰⁶

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

94E5-94E11

(Hales, 1997.3.30)

94E-94E

(Hales and Fuller, 1996)

94E3-95A3

(determined by in situ hybridisation)

(Hales and Fuller, 1995)

Experimentally Determined Recombination Data

Location

3-78

(FlyBase, 2016)

3-79.9

(Comeron et al., 2012)

Left of (cM)

(Hales and Fuller, 1997)

Right of (cM)

(Hales and Fuller, 1997)

Notes

Stocks and Reagents

Stocks (4)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

80071

e⁴ fzo¹/TM3, Sb¹

Kyoto

201331

y¹ w^67c23; P{GSV3}cnc^GS8035/TM3, Sb¹ Ser¹

VDRC

v106072

P{KK104907}VIE-260B

v1407

w¹¹¹⁸; P{GD196}v1407

Genomic Clones (12)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (5)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

DPiM_IP02808

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0011596

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

IP03008

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0011596

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Hales and Fuller, 1997)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Area matching Drosophila Fzo gene, Acc. No. U95821.

(Davies, 2001.3.15)

fzo has been cloned and characterised. fzo encodes a predicted transmembrane GTPase that is required for mitochondrial fusion during spermatogenesis.

(Hales and Fuller, 1997)

At the round spermatid stage all mitochondria in each haploid spermatid fuse into two large derivatives that interweave to form the nebenkern, in fzo mutants the mitochondria aggregate but fail to fuse. The defect is specific to fusion as each unfused mitochondrion elongates normally.

(Hales and Fuller, 1995)

Relationship to Other Genes

Source for database merge of

Source for merge of: fzo anon-WO0125274.1 anon-WO0125274.25 anon-WO0125274.26

(FlyBase, 1996-)

Additional comments

Source for merge of fzo anon-WO0125274.1 anon-WO0125274.25 anon-WO0125274.26 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (11)

Reported As

Symbol Synonym

CG4568

(Keleman et al., 2009.8.5, Vibranovski et al., 2009, Laviolette et al., 2005)

CG5315

(Lassetter et al., 2023)

Fzo

(Fedorova et al., 2023, Varuzhanyan and Chan, 2020, Kandul et al., 2019, Hsiao et al., 2014)

MFN1

(Mendez et al., 2016)

anon-WO0125274.1

anon-WO0125274.25

anon-WO0125274.26

mfn1

(Mendez et al., 2016)

Name Synonyms

Mitofusin

(Praefcke and McMahon, 2004)

fuzzy onions

(Cruz-Becerra et al., 2016, Lim et al., 2012, Moon et al., 2011, Vibranovski et al., 2009, Praefcke and McMahon, 2004)

Secondary FlyBase IDs

FBgn0044369
FBgn0044370
FBgn0044371

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 41 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

42745

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

O18412

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

O18412

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

O18412

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0011596

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

42745/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0011596

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0011596

FlyMine - An integrated database for Drosophila genomics

FBgn0011596

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG4568

MARRVEL_MODEL - MARRVEL (model organism gene)

42745

Linkouts

BioGRID - A database of protein and genetic interactions.

67689

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0011596

DroID - A comprehensive database of gene and protein interactions.

FBgn0011596

DRSC - Results frm RNAi screens

FBgn0011596

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

fzo_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0011596

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0011596

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

Flygut - An atlas of the Drosophila adult midgut

FBgn0011596

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0011596

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (96)

The following external sites may use different assemblies or annotations than FlyBase.

2.11

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