FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\Kdm4A
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General Information
Symbol
Dmel\Kdm4A
Species
D. melanogaster
Name
Lysine demethylase 4A
Annotation Symbol
CG15835
Feature Type
protein_coding_gene
FlyBase ID
FBgn0033233
Gene Model Status
Current
Stock Availability
8 publicly available
Enzyme Name (EC)
[histone H3]-trimethyl-L-lysine(9) demethylase (1.14.11.66)
[histone H3]-trimethyl-L-lysine(36) demethylase (1.14.11.69)
Gene Summary
Lysine (K)-specific demethylase 4A (Kdm4A) encodes a histone lysine demethylase that catalyzes removal of methyl groups using alpha-ketoglutarate as a cofactor. It demethylates H3K36me3 and is implicated in the demethylation of H3K9me3 and H3K56me3. Its roles include transcription, DNA repair, and heterochromatin silencing. [Date last reviewed: 2019-09-26] (FlyBase Gene Snapshot)
All Summaries
Also Known As

dKDM4A, Histone demethylase 4A

Key Links
Genomic Location
Cytogenetic map
43F2-43F2
Sequence location
Recombination map
2-57
RefSeq locus
NT_033778 REGION:7922775..7924988
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (13 terms)
Molecular Function (5 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
enables histone H3K36me2/H3K36me3 demethylase activity
inferred from mutant phenotype
(Lloret-Llinares et al., 2008)
inferred from direct assay
(Lin et al., 2008)
enables histone H3K56me2/H3K56me3 demethylase activity
inferred from mutant phenotype
(Colmenares et al., 2017)
enables histone H3K9me2/H3K9me3 demethylase activity
inferred from mutant phenotype
(Lloret-Llinares et al., 2008)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables histone H3K36 demethylase activity
inferred from biological aspect of ancestor with PANTHER:PTN000075207
(GO Reference Genome Project, 2011-)
inferred from sequence or structural similarity with UniProtKB:O75164
(Gene Ontology Curators, 2002-)
enables histone H3K9 demethylase activity
inferred from biological aspect of ancestor with PANTHER:PTN000075207
(GO Reference Genome Project, 2011-)
Biological Process (5 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
involved_in circadian behavior
inferred from mutant phenotype
(Shalaby et al., 2018)
involved_in positive regulation of gene expression
inferred from mutant phenotype
(Lorbeck et al., 2010)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
involved_in chromatin remodeling
inferred from biological aspect of ancestor with PANTHER:PTN000075014
(GO Reference Genome Project, 2011-)
involved_in negative regulation of DNA-templated transcription
inferred from sequence or structural similarity with UniProtKB:O75164
(Gene Ontology Curators, 2002-)
involved_in regulation of gene expression
inferred from biological aspect of ancestor with PANTHER:PTN000075014
(GO Reference Genome Project, 2011-)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
located_in heterochromatin
inferred from direct assay
(Swenson et al., 2016)
located_in nucleus
inferred from direct assay
(Lloret-Llinares et al., 2008)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
is_active_in chromatin
inferred from biological aspect of ancestor with PANTHER:PTN000075014
(GO Reference Genome Project, 2011-)
is_active_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN000075014
(GO Reference Genome Project, 2011-)
located_in nucleus
inferred from sequence or structural similarity with UniProtKB:O75164
(Gene Ontology Curators, 2002-)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the JHDM3 histone demethylase family. (Q9V333)
Protein Signatures (InterPro)
Catalytic Activity (EC/Rhea)
histone H3K56me2/H3K56me3 demethylase activity
RHEA 85927: RHEA 85931: histone H3K36me2/H3K36me3 demethylase activity
N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2 (1.14.11.69)
RHEA 60236: histone H3K9me2/H3K9me3 demethylase activity
N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2 (1.14.11.66)
RHEA 60200:
Summaries
Gene Snapshot
Lysine (K)-specific demethylase 4A (Kdm4A) encodes a histone lysine demethylase that catalyzes removal of methyl groups using alpha-ketoglutarate as a cofactor. It demethylates H3K36me3 and is implicated in the demethylation of H3K9me3 and H3K56me3. Its roles include transcription, DNA repair, and heterochromatin silencing. [Date last reviewed: 2019-09-26]
Gene Group (FlyBase)
JMJC FAMILY HISTONE DEMETHYLASES -
The Jumonji C (JmjC) domain-containing demethlyases catalyze histone lysine or arginine demethylation through an oxidative reaction that requires iron Fe(II) and α-ketoglutarate as cofactors. (Adapted from FBrf0195283).
Protein Function (UniProtKB)
Probable histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).
(UniProt, Q9V333)
Summary (Interactive Fly)

histone demethylase - regulates H3K36me3 levels - regulates heterochromatin organization and function - Jun recruits the HP1a/KDM4A complex to its gene body region upon osmotic stress to reduce H3K36 methylation levels and disrupt H3K36 methylation-dependent histone deacetylation - along with Kdm4B, Kdm4A is essential for mediating ecdysteroid hormone signaling during larval development M

Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
2

Please see the JBrowse view of Dmel\Kdm4A for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9V333)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.41

Gene model reviewed during 5.49

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Kdm4A-RA
FBtr0088886
NM_136487
2022
495
Kdm4A-RB
FBtr0309844
NM_001259265
2004
489
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Kdm4A-PA
FBpp0087961
57.0
495
7.27
Q9V333
NP_610331
AAF59172
Kdm4A-PB
FBpp0301578
56.2
489
7.49
A0A0B4K7U3
NP_001246194
AFH07949
Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Kdm4A using the Feature Mapper tool.

External Data
Crossreferences
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

0.74

Transcript Expression
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in heterochromatin
inferred from direct assay
(Swenson et al., 2016)
located_in nucleus
inferred from direct assay
(Lloret-Llinares et al., 2008)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Kdm4A in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 4-6
  • Stages(s) 7-8
  • Stages(s) 9-10
  • Stages(s) 11-12
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 8 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 14 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Kdm4A
Transgenic constructs containing regulatory region of Kdm4A
Aberrations (Deficiencies and Duplications) ( 1 )
Inferred from experimentation ( 1 )
Gene disrupted in
Df(2R)Exel6055
(Ryder, 2004.4.26)
Inferred from location ( 4 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (19)
Hsap\KDM4A
10 of 14
Yes
Yes
Hsap\KDM4B
10 of 14
Yes
Yes
1  
Hsap\KDM4C
10 of 14
Yes
Yes
Hsap\KDM4D
8 of 14
No
Yes
Hsap\KDM4E
8 of 14
No
Yes
Hsap\KDM4F
6 of 14
No
Yes
Hsap\BRPF1
1 of 14
No
No
Hsap\BRPF3
1 of 14
No
No
Hsap\JADE1
1 of 14
No
No
1  
Hsap\JADE2
1 of 14
No
No
Hsap\JADE3
1 of 14
No
No
Hsap\JARID2
1 of 14
No
No
Hsap\KDM5A
1 of 14
No
No
Hsap\KDM5B
1 of 14
No
No
Hsap\KDM5C
1 of 14
No
No
Hsap\KDM5D
1 of 14
No
No
Hsap\MLLT6
1 of 14
No
No
Hsap\MLLT10
1 of 14
No
No
2  
Hsap\PHF14
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (17)
Rnor\Kdm4a
9 of 14
Yes
Yes
Rnor\Kdm4b
9 of 14
Yes
Yes
Rnor\Kdm4d
9 of 14
Yes
Yes
Rnor\Kdm4c
7 of 14
No
Yes
Rnor\Brd1
1 of 14
No
No
Rnor\Brpf1
1 of 14
No
No
Rnor\Brpf3
1 of 14
No
No
Rnor\Jade1
1 of 14
No
No
Rnor\Jade2
1 of 14
No
No
Rnor\Jarid2
1 of 14
No
No
Rnor\Kdm4dl2
1 of 14
No
Yes
Rnor\Kdm5a
1 of 14
No
No
Rnor\Kdm5b
1 of 14
No
No
Rnor\Kdm5c
1 of 14
No
No
Rnor\Kdm5d
1 of 14
No
No
Rnor\Mllt10
1 of 14
No
No
Rnor\Phf14
1 of 14
No
No
Mus musculus (laboratory mouse) (18)
Mmus\Kdm4b
9 of 14
Yes
Yes
Mmus\Kdm4c
9 of 14
Yes
Yes
Mmus\Kdm4d
9 of 14
Yes
Yes
Mmus\Kdm4a
8 of 14
No
Yes
Mmus\Brd1
1 of 14
No
No
Mmus\Brpf1
1 of 14
No
No
Mmus\Brpf3
1 of 14
No
No
Mmus\Jade1
1 of 14
No
No
Mmus\Jade2
1 of 14
No
No
Mmus\Jade3
1 of 14
No
No
Mmus\Jarid2
1 of 14
No
No
1  
Mmus\Kdm5a
1 of 14
No
No
Mmus\Kdm5b
1 of 14
No
No
Mmus\Kdm5c
1 of 14
No
No
Mmus\Kdm5d
1 of 14
No
No
Mmus\Mllt6
1 of 14
No
No
Mmus\Mllt10
1 of 14
No
No
Mmus\Phf14
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (10)
Xtro\kdm4b
7 of 13
Yes
Yes
Xtro\gtf3c5
5 of 13
No
No
Xtro\kdm4a
5 of 13
No
No
Xtro\kdm4c
5 of 13
No
Yes
Xtro\faf2
1 of 13
No
No
Xtro\gabarapl1
1 of 13
No
No
Xtro\jarid2
1 of 13
No
No
Xtro\LOC100492975
1 of 13
No
No
Xtro\phldb1
1 of 13
No
No
Xtro\slco2a1
1 of 13
No
No
Danio rerio (Zebrafish) (17)
Drer\kdm4aa
10 of 14
Yes
Yes
Drer\kdm4ab
10 of 14
Yes
Yes
Drer\kdm4b
8 of 14
No
Yes
Drer\kdm4c
8 of 14
No
Yes
Drer\brd1a
1 of 14
No
No
Drer\brd1b
1 of 14
No
No
Drer\brpf3b
1 of 14
No
No
Drer\jade1
1 of 14
No
No
Drer\jade2
1 of 14
No
No
Drer\jade3
1 of 14
No
No
Drer\jarid2a
1 of 14
No
No
Drer\jarid2b
1 of 14
No
No
Drer\kdm5a
1 of 14
No
No
Drer\kdm5ba
1 of 14
No
No
Drer\kdm5bb
1 of 14
No
No
Drer\kdm5c
1 of 14
No
No
Drer\mllt10
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (4)
Cele\jmjd-2
10 of 14
Yes
Yes
Cele\lin-49
1 of 14
No
No
Cele\phf-14
1 of 14
No
No
Cele\rbr-2
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (7)
Agam\AgaP_AGAP006770
10 of 12
Yes
Yes
Agam\AgaP_AGAP011180
5 of 12
No
No
Agam\AgaP_AGAP000754
1 of 12
No
No
Agam\AgaP_AGAP004854
1 of 12
No
No
Agam\AgaP_AGAP005541
1 of 12
No
No
Agam\AgaP_AGAP006776
1 of 12
No
No
Agam\AgaP_AGAP007617
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (14)
Atha\AT2G38950
2 of 13
Yes
No
Atha\AT5G46910
2 of 13
Yes
No
Atha\JMJ14
2 of 13
Yes
No
Atha\JMJ18
2 of 13
Yes
No
Atha\MEE27
2 of 13
Yes
No
Atha\PKDM7D
2 of 13
Yes
No
Atha\AT1G20670
1 of 13
No
No
Atha\AT1G63490
1 of 13
No
No
Atha\AT1G76380
1 of 13
No
No
Atha\AT1G77800
1 of 13
No
No
Atha\AT3G14740
1 of 13
No
No
Atha\AT5G55040
1 of 13
No
No
Atha\ELF6
1 of 13
No
No
Atha\REF6
1 of 13
No
No
Saccharomyces cerevisiae (Brewer's yeast) (6)
Scer\RPH1
8 of 13
Yes
Yes
Scer\GIS1
7 of 13
No
Yes
Scer\ECM5
1 of 13
No
No
Scer\JHD2
1 of 13
No
No
Scer\NTO1
1 of 13
No
No
Scer\SNT2
1 of 13
No
No
Schizosaccharomyces pombe (Fission yeast) (6)
Spom\jmj2
2 of 12
Yes
No
Spom\jmj3
2 of 12
Yes
No
Spom\lid2
1 of 12
No
No
Spom\msc1
1 of 12
No
No
Spom\nto1
1 of 12
No
No
Spom\snt2
1 of 12
No
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Kdm4A. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (7)
Kdm4B
10 of 13
Jarid2
3 of 13
Kdm5
3 of 13
Br140
1 of 13
CG15439
1 of 13
rno
1 of 13
seq
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 1 )
    Modifiers Based on Experimental Evidence ( 2 )
    Allele
    Disease
    Interaction
    References
    Kdm4AKG04636
    ameliorates  Huntington's disease
    modeled by Hsap\HTTQ93.ex1.UAS
    (Song et al., 2018)
    Kdm4AGD9133
    ameliorates  tauopathy
    modeled by Hsap\MAPTR406W.UAS
    (Park et al., 2019)
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    KDM4A; lysine demethylase 4A
    10 of 14
    609764
        KDM4B; lysine demethylase 4B
        10 of 14
        609765
         
        KDM4C; lysine demethylase 4C
        10 of 14
        605469
            KDM4D; lysine demethylase 4D
            8 of 14
            609766
                KDM4E; lysine demethylase 4E
                8 of 14
                616581
                    KDM4F; lysine demethylase 4F
                    6 of 14
                        Functional Complementation Data
                        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                        Interactions
                        Summary of Physical Interactions
                        Summary of Genetic Interactions
                        Interaction Browsers
                        View in FlyBase Interactions Browser   View in MIST tool (external link)
                        Please look at the allele data for full details of the genetic interactions
                        Starting gene(s)
                        Interaction type
                        Interacting gene(s)
                        Reference
                        Starting gene(s)
                        Interaction type
                        Interacting gene(s)
                        Reference
                        smo
                        enhanceable
                        Kdm4A
                        (Shalaby et al., 2017)
                        External Data
                        Linkouts
                        BioGRID - A database of protein and genetic interactions.
                        DroID - A comprehensive database of gene and protein interactions.
                        MIST (protein-protein) - An integrated Molecular Interaction Database
                        Pathways
                        Signaling Pathways (FlyBase)
                        Metabolic Pathways
                        FlyBase
                        External Links
                        External Data
                        Class of Gene
                        Genomic Location and Detailed Mapping Data
                        Chromosome (arm)
                        2R
                        Recombination map
                        2-57
                        Cytogenetic map
                        43F2-43F2
                        Sequence location
                        FlyBase Computed Cytological Location
                        Cytogenetic map
                        Evidence for location
                        43F2-43F2
                        Limits computationally determined from genome sequence between P{lacW}lin19k01207&P{lacW}rnh1k07624 and P{lacW}CSN4k08018&P{lacW}l(2)k08504k08504
                        Experimentally Determined Cytological Location
                        Cytogenetic map
                        Notes
                        References
                        Experimentally Determined Recombination Data
                        Location

                        2-57

                        (FlyBase, 2016)

                        2-57.2

                        (Comeron et al., 2012)
                        Left of (cM)
                        Right of (cM)
                        Notes
                        Stocks and Reagents
                        Stocks (8)
                        Genomic Clones (9)
                         

                        Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

                        cDNA Clones (32)
                         

                        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

                        cDNA clones, fully sequenced
                        BDGP DGC clones
                        Other clones
                        Drosophila Genomics Resource Center cDNA clones

                        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                        cDNA Clones, End Sequenced (ESTs)
                        BDGP DGC clones
                        Other clones
                        RNAi and Array Information
                        Linkouts
                        DRSC - Results frm RNAi screens
                        Antibody Information
                        Laboratory Generated Antibodies
                         

                        polyclonal

                        (Lin et al., 2012)
                        Commercially Available Antibodies
                         
                        Cell Line Information
                        Publicly Available Cell Lines
                         
                          Other Stable Cell Lines
                           
                          Other Comments
                          Relationship to Other Genes
                          Source for database merge of
                          Additional comments
                          Nomenclature History
                          Source for database identify of

                          Source for identity of: Kdm4A CG15835

                          (Lin et al., 2008)
                          Nomenclature comments
                          Etymology
                          Synonyms and Secondary IDs (13)
                          Datasets (2)
                          Study focus (2)
                          Experimental Role
                          Project
                          Project Type
                          Title
                          • bait_protein
                          modENCODE_chromatin_proteins_cells
                          Genome-wide localization of chromosomal proteins in cell lines by ChIP-chip and ChIP-Seq.
                          • bait_protein
                          modENCODE_chromatin_proteins_flies
                          Genome-wide localization of chromosomal proteins in fly tissues by ChIP-chip and ChIP-Seq.
                          Study result (0)
                          Result
                          Result Type
                          Title
                          External Crossreferences and Linkouts ( 38 )
                          Sequence Crossreferences
                          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                          UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
                          UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
                          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                          Other crossreferences
                          AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
                          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                          DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
                          EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
                          FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
                          FlyMine - An integrated database for Drosophila genomics
                          InterPro - A database of protein families, domains and functional sites
                          KEGG Genes - Molecular building blocks of life in the genomic space.
                          MARRVEL_MODEL - MARRVEL (model organism gene)
                          Linkouts
                          BioGRID - A database of protein and genetic interactions.
                          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                          DroID - A comprehensive database of gene and protein interactions.
                          DRSC - Results frm RNAi screens
                          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                          Flygut - An atlas of the Drosophila adult midgut
                          Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
                          MIST (protein-protein) - An integrated Molecular Interaction Database
                          Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                          References (78)