FlyBase Gene Report: Dmel\ppk11

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Gene: Dmel\ppk11

General Information

Symbol

Dmel\ppk11

Species

D. melanogaster

Name

pickpocket 11

Annotation Symbol

CG34058

Feature Type

protein_coding_gene

FlyBase ID

FBgn0065109

Gene Model Status

Stock Availability

8 publicly available

Gene Summary

pickpocket 11 (ppk11) encodes a predicted member of the Degenerin/Epithelial Sodium Channel family. In the larval stage, it is expressed in the terminal organ for salt taste and tracheal cells for liquid clearance. It functions in salt taste in adult flies. [Date last reviewed: 2019-02-28] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

Sequence location

2L:9,771,155..9,775,030 [-]

Recombination map

2-36

RefSeq locus

NT_033779 REGION:9771155..9775030

Sequence

Get Decorated FASTA

Genomic Maps

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (11 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

contributes_to ligand-gated sodium channel activity

inferred from biological aspect of ancestor with PANTHER:PTN000189658

(GO Reference Genome Project, 2011-)

enables sodium channel activity

inferred from sequence or structural similarity with MGI:MGI:101782

(Gene Ontology Curators, 2002-)

inferred from electronic annotation with InterPro:IPR001873, InterPro:IPR020903

(InterPro Project Members, 2004-)

Biological Process (7 terms)

Terms Based on Experimental Evidence (5 terms)

CV Term

Evidence

References

involved_in liquid clearance, open tracheal system

inferred from mutant phenotype

(Liu et al., 2003)

involved_in regulation of synaptic activity

inferred from mutant phenotype

(Younger et al., 2013)

involved_in response to salt stress

inferred from mutant phenotype

(Liu et al., 2003)

involved_in salt aversion

inferred from mutant phenotype

(Liu et al., 2003)

involved_in sensory perception of salty taste

inferred from mutant phenotype

(Liu et al., 2003)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in sodium ion transmembrane transport

inferred from biological aspect of ancestor with PANTHER:PTN000189658

(GO Reference Genome Project, 2011-)

involved_in sodium ion transport

inferred from sequence or structural similarity with MGI:MGI:101782

(Gene Ontology Curators, 2002-)

inferred from electronic annotation with InterPro:IPR001873, InterPro:IPR020903

(InterPro Project Members, 2004-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

located_in membrane

inferred from electronic annotation with InterPro:IPR001873, InterPro:IPR020903

(InterPro Project Members, 2004-)

inferred from sequence or structural similarity with MGI:MGI:101782

(Gene Ontology Curators, 2002-)

is_active_in plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN000189658

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

PICKPOCKET ION CHANNELS

Protein Family (UniProt)

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (Q9VL84)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

pickpocket 11 (ppk11) encodes a predicted member of the Degenerin/Epithelial Sodium Channel family. In the larval stage, it is expressed in the terminal organ for salt taste and tracheal cells for liquid clearance. It functions in salt taste in adult flies. [Date last reviewed: 2019-02-28]

Gene Group (FlyBase)

PICKPOCKET ION CHANNELS -: The degenerin (DEG)/epithial Na⁺ channel (ENaC) gene family, known as the pickpocket genes in Drosophila, encodes subunits of non-voltage gated, amiloride-sensitive cation channels. Channels may be formed by homo- or heteromeric arrangements of subunits. Each subunit has two transmembrane domains and a large cysteine-rich extracellular loop domain. They are functionally diverse, with roles in fluid and salt absorbance, mechanosensation and chemosensation. (Adapted from FBrf0220901 and FBrf0159284).

Protein Function (UniProtKB)

Part of a complex that plays a role in tracheal liquid clearance. In both larvae and adults, contributes to the behavioral response to salt. Probable role in sodium transport.

(UniProt, Q9VL84)

Summary (Interactive Fly)

DEG/ENaC sodium channel subunits - homeostatic modulation of presynaptic neurotransmitter release

Interactive Fly

Gene Model and Products

Number of Transcripts

1

Number of Unique Polypeptides

1

Please see the JBrowse view of Dmel\ppk11 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VL84)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Dicistronic annotation based on RT-PCR data (FBrf0222751).

Gene model reviewed during 5.47

Gene model reviewed during 6.10

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0100831

3212

516

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

FBpp0100162

60.0

516

8.27

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Q9VL84

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ppk11 using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

NA

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 15 -- 17

tracheal section

(Liu et al., 2003)

embryonic/larval tracheal dorsal trunk

(Liu et al., 2003)

embryonic stage 16 -- 17

embryonic/larval tracheal transverse connective

(Liu et al., 2003)

embryonic stage 17

secondary tracheal branch

(Liu et al., 2003)

tracheal tip cell

(Liu et al., 2003)

Additional Descriptive Data

ppk11 expression is first detected in the posterior dorsal trunk at embryonic stage 15. Expression extends to the anterior dorsal trunk, then to primary branches at stage 16. During stage 17, expression extends to the secondary branches.

(Liu et al., 2003)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

Reporter: P{ppk11-GAL4.L}

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic/larval tracheal section

(Liu et al., 2003)

tracheal tip cell

(Liu et al., 2003)

embryonic/larval tracheal dorsal trunk

(Liu et al., 2003)

primary tracheal branch

(Liu et al., 2003)

secondary tracheal branch

(Liu et al., 2003)

embryonic/larval tracheal transverse connective

(Liu et al., 2003)

second instar larval stage

terminal organ | subset

(Liu et al., 2003)

neuron | subset of terminal organ

(Liu et al., 2003)

neuron | subset

(Liu et al., 2003)

larval tracheal system

(Liu et al., 2003)

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\ppk11 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\ppk11

View exonic expression by tissue for Dmel\ppk11

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

34299/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0065109

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0065109

Images

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 4 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 8 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of ppk11

Transgenic constructs containing regulatory region of ppk11

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 9 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

ppk11^f02053

viable, with Dcr-2^UAS.cDa, Scer\GAL4^e22c, Scer\GAL4^sqh.PW

ppk11^KK106798

Sterility

Allele

ppk11^f02053

Other Phenotypes

Allele

abnormal neurophysiology, with Scer\GAL4^elav.PLu

abnormal neurophysiology | third instar larval stage

abnormal neurophysiology | third instar larval stage, with Scer\GAL4^VGlut1-OK371

abnormal neurophysiology | third instar larval stage (with Df(2L)BSC240)

ppk11^f02053

abnormal taste perception, with Scer\GAL4^elav.PLu

abnormal taste perception, with Scer\GAL4^GH86

ppk11^DN.UAS

abnormal taste perception, with Scer\GAL4^hs.PB

ppk11^RNAi.UAS

Phenotype manifest in

Allele

terminal organ, with Scer\GAL4^elav.PLu

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (9)

4 of 14

Yes

No

4 of 14

Yes

No

2

4 of 14

Yes

No

4 of 14

Yes

No

4 of 14

Yes

No

4 of 14

Yes

No

3 of 14

No

No

3 of 14

No

No

1

2 of 14

No

No

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (8)

5 of 14

Yes

No

4 of 14

No

No

3 of 14

No

No

3 of 14

No

No

3 of 14

No

No

3 of 14

No

No

3 of 14

No

No

2 of 14

No

No

Mus musculus (laboratory mouse) (8)

5 of 14

Yes

No

4 of 14

No

No

4 of 14

No

No

4 of 14

No

No

3 of 14

No

No

3 of 14

No

No

3 of 14

No

No

2 of 14

No

No

Xenopus tropicalis (Western clawed frog) (10)

1 of 13

Yes

No

1 of 13

Yes

No

1 of 13

Yes

No

Xtro\LOC100497753

1 of 13

Yes

No

Xtro\LOC101731449

1 of 13

Yes

No

1 of 13

Yes

No

1 of 13

Yes

Yes

1 of 13

Yes

No

1 of 13

Yes

No

1 of 13

Yes

No

Danio rerio (Zebrafish) (6)

4 of 14

Yes

No

4 of 14

Yes

No

3 of 14

No

No

3 of 14

No

No

3 of 14

No

No

3 of 14

No

No

Caenorhabditis elegans (Nematode, roundworm) (30)

6 of 14

Yes

No

6 of 14

Yes

No

6 of 14

Yes

No

6 of 14

Yes

No

6 of 14

Yes

No

5 of 14

No

No

4 of 14

No

No

4 of 14

No

No

4 of 14

No

No

4 of 14

No

No

3 of 14

No

No

3 of 14

No

No

3 of 14

No

No

3 of 14

No

Yes

2 of 14

No

No

2 of 14

No

No

2 of 14

No

Yes

2 of 14

No

No

2 of 14

No

Yes

2 of 14

No

Yes

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

Cele\Y57G11C.44

1 of 14

No

Yes

Anopheles gambiae (African malaria mosquito) (24)

Agam\AgaP_AGAP006703

5 of 12

Yes

Yes

Agam\AgaP_AGAP006704

5 of 12

Yes

Yes

Agam\AgaP_AGAP001602

3 of 12

No

No

Agam\AgaP_AGAP009590

3 of 12

No

No

Agam\AgaP_AGAP011103

3 of 12

No

No

Agam\AgaP_AGAP011433

3 of 12

No

No

Agam\AgaP_AGAP011610

3 of 12

No

No

Agam\AgaP_AGAP011611

3 of 12

No

No

Agam\AgaP_AGAP012279

3 of 12

No

No

Agam\AgaP_AGAP000657

2 of 12

No

No

Agam\AgaP_AGAP000840

2 of 12

No

No

Agam\AgaP_AGAP001631

2 of 12

No

No

Agam\AgaP_AGAP004474

2 of 12

No

No

Agam\AgaP_AGAP005516

2 of 12

No

No

Agam\AgaP_AGAP006720

2 of 12

No

No

Agam\AgaP_AGAP007945

2 of 12

No

No

Agam\AgaP_AGAP008378

2 of 12

No

No

Agam\AgaP_AGAP008380

2 of 12

No

No

Agam\AgaP_AGAP009789

2 of 12

No

No

Agam\AgaP_AGAP010430

2 of 12

No

No

Agam\AgaP_AGAP010967

2 of 12

No

No

Agam\AgaP_AGAP007084

1 of 12

No

No

Agam\AgaP_AGAP010146

1 of 12

No

No

1 of 12

No

No

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:ppk11. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (31)

7 of 13

7 of 13

6 of 13

6 of 13

6 of 13

6 of 13

6 of 13

5 of 13

5 of 13

5 of 13

4 of 13

4 of 13

4 of 13

4 of 13

4 of 13

4 of 13

4 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 3 )

Human Ortholog

Disease

Evidence

References

SCNN1G; sodium channel epithelial 1 subunit gamma

model of bronchiectasis 3

IEA

(FlyBase, 2019-)

SCNN1B; sodium channel epithelial 1 subunit beta

model of bronchiectasis 1

IEA

(FlyBase, 2019-)

model of Liddle syndrome

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

ameliorates nervous system disease

modeled by Atpα^CJ5

(Talsma et al., 2014)

modeled by Atpα^DTS1

(Talsma et al., 2014)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

ASIC1; acid sensing ion channel subunit 1

4 of 14

ASIC2; acid sensing ion channel subunit 2

4 of 14

ASIC3; acid sensing ion channel subunit 3

4 of 14

ASIC4; acid sensing ion channel subunit family member 4

4 of 14

SCNN1B; sodium channel epithelial 1 subunit beta

4 of 14

SCNN1G; sodium channel epithelial 1 subunit gamma

4 of 14

bronchiectasis 3

SCNN1A; sodium channel epithelial 1 subunit alpha

3 of 14

SCNN1D; sodium channel epithelial 1 subunit delta

3 of 14

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

coimmunoprecipitation, western blot

(Orr et al., 2017)

anti tag coimmunoprecipitation, anti tag western blot

(Orr et al., 2017)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0065109

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Stimuli-sensing channels

Class of Gene

gene_with_dicistronic_mRNA

(FlyBase Genome Annotators, 2016)

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

2L

Recombination map

2-36

Cytogenetic map

Sequence location

2L:9,771,155..9,775,030 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

30C8-30C9

Limits computationally determined from genome sequence between P{lacW}zf30C^k02506&P{EP}und^EP424 and P{lacW}l(2)k06416^k06416&P{lacW}sop^k04603

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

30D1-30D1

(Welsh, 2003.1.15)

Experimentally Determined Recombination Data

Location

2-36

(FlyBase, 2016)

2-31.7

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (8)

Aberrations including deletions of this gene Aberrations including duplications of this gene

18507

w¹¹¹⁸; PBac{WH}ppk11^f02053

23781

w¹¹¹⁸; Mi{ET1}ppk11^MB02012

26253

y¹ v¹; P{TRiP.JF02152}attP2

M2L-2524

y¹ w¹¹¹⁸; ppk11^SK1 P{neoFRT}40A/CyO-Tb

M2L-2525

y¹ w¹¹¹⁸; ppk11^SK2 P{neoFRT}40A/CyO-Tb

2LG-2005

y² VhaAC39-1^cho-1 v¹; P{U6-ppk11.NIG.sgRNA}attP40/CyO

v330319

P{VSH330319}attP40

v107741

P{KK106798}VIE-260B

Genomic Clones (11)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (1)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD34273

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0065109

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

ppk11 may have a role in liquid clearance from the tracheal system.

(Liu et al., 2003)

Relationship to Other Genes

Source for database merge of

Additional comments

One or more of the processed transcripts for this gene contain(s) two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by CG34059 and CG34058.

(FlyBase Genome Annotators, 2016)

Annotation CG4110 split into CG34058 (ppk11) and CG34059 (ppk16) in release 4.3 of the genome annotation.

(FlyBase Genome Annotators, 2005)

Source for split of CG4110 (into ppk11 ppk16) was sequence comparison ( date:030311 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

CG34058

(National Institute of Genetics Fly Stocks, 2022-, Meadows, 2017.1.11, Zelle et al., 2013, Tsubouchi et al., 2012, Keleman et al., 2009.8.5, Perkins et al., 2009.3.31, FlyBase Genome Annotators, 2005)

CG4110

(Giannakou and Dow, 2001)

ENaC

(Wenner and Pekala, 2022)

PPK11

(Ali et al., 2022, Colomb et al., 2007, Tobin and Bargmann, 2004, Liu et al., 2003, Welsh, 2003.1.15)

Ppk11

(Talsma et al., 2014)

ppk11

(Asefa et al., 2024, Kaulich et al., 2023, Bianchi, 2021, Guo et al., 2020, He et al., 2019, Kim et al., 2018, FlyBase Genome Annotators, 2016, Younger et al., 2013, Zelle et al., 2013, Zhang et al., 2013, Ben-Shahar, 2012.2.9, Liu et al., 2012, Tsubouchi et al., 2012, Ben-Shahar, 2011, Chen et al., 2010, Sun et al., 2008)

Name Synonyms

Pickpocket11

(Tobin and Bargmann, 2004)

pickpocket 11

(Zelle et al., 2013, Ben-Shahar, 2012.2.9, Tsubouchi et al., 2012)

pickpocket11

(Nair et al., 2021, Younger et al., 2013)

Secondary FlyBase IDs

FBgn0032146
FBgn0054058

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 24 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

34299

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AY226542

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VL84

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9VL84

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VL84

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

34299/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0065109

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0065109

FlyMine - An integrated database for Drosophila genomics

FBgn0065109

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG34058

MARRVEL_MODEL - MARRVEL (model organism gene)

34299

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0065109

DRSC - Results frm RNAi screens

FBgn0065109

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0065109

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0065109

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC034701

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Stimuli-sensing channels

References (48)