FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
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Citation
Ephrussi, A., St. Johnston, D. (2004). Seeing is believing. The bicoid morphogen gradient matures.  Cell 116(2): 143--152.
FlyBase ID
FBrf0167369
Publication Type
Note
Abstract
Although Cell has a long history of publishing some of the most significant advances in developmental biology, the back to back papers by Driever and Nüsslein-Volhard on the role of the Bicoid gradient in patterning the Drosophila embryo stand out as the first molecular demonstration of two of the longest standing concepts of the field, namely localized cytoplasmic determinants and morphogen gradients. Here we discuss the impact of this ground-breaking work and review recent results on bicoid mRNA localization and the dual role of Bicoid as a transcription and translation factor.
PubMed ID
14744427
PubMed Central ID
DOI
10.1016/s0092-8674(04)00037-6
Related Publication(s)
Research paper

The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner.
Driever and Nusslein-Volhard, 1988, Cell 54(2 Suppl): 95--104 [FBrf0047672]

A gradient of bicoid protein in Drosophila embryos.
Driever and Nusslein-Volhard, 1988, Cell 54(2): 83--93 [FBrf0047668]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell
    Title
    Cell
    Publication Year
    1974-
    ISBN/ISSN
    0092-8674
    Data From Reference