FB2026_02 , released June 18, 2026
Recombinant Construct: P{Ddc-GAL4.L}
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General Information
Symbol
P{Ddc-GAL4.L}
FlyBase ID
FBtp0012451
Feature type
transgenic_transposable_element
Component Allele(s)
Also Known As
Ddc-GAL4, DdCGAL4, (Ddc)-Gal4, dopa decarboxylase (ddc)-GAL4
Size
Expression Data
GAL4 reporter/driver
Associated insertion(s)
Molecular map
Description and Uses
Construct components
Component allele Scer\GAL4Ddc.PL
Transgenic product class
Component
Use(s)
Regulatory region(s)
Description

The Ddc promoter regulates expression of a GAL4 driver.

Sequence Data
Sequence (FB)
Associated Sequence Data
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
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Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
microinjection
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Drives expression in dopaminergic and serotonergic neurons, and their precursors.

ScerGAL4Ddc.PL drives expression very weakly in the ellipsoid and the fan-shaped bodies.

ScerGAL4Ddc.PL drives expression in a subset of the dopaminergic PPL2ab neurons and in the majority of the PAM neurons (includes MB-M3 and MB-MP1 neurons).

Expression observed in neurons that innervate the mushroom body horizontal lobes and the subsesophageal ganglion.

Expression in the midgut is found in a distinct group of Dh31-expressing enteroendocrine cells located at the junction region of the anterior midgut and the acid-secreting portion of the larval midgut. This junction region occurs at a conspicuous and characteristic U-shaped bend in the gut. These are referred to as the "midgut junction Dh31-expressing cells".

Expression is seen in dopaminergic and serotonergic neurons and their precursors, totalling 9-11 neurons per abdominal half-neuromere by larval stage L1. A precise pattern can be found in FBrf0160715.

Expression is observed in Ddc-expressing neurons.

 
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (2)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (32)
Reported As
Symbol Synonym
(Ddc)-GAL4
3,4-dihydroxyphenylalanine-L-decarboxylase (Ddc)-Gal4
DDC-GAL4 (HL8)
Ddc(4.36)-GAL4
Ddc-GAL4
(Idowu et al., 2026, Lo Piccolo et al., 2026, Banerjee et al., 2025, Kajtor et al., 2025, Meimoun et al., 2025, Serebryany-Piavsky et al., 2025, Chitre et al., 2024, Watanabe et al., 2024, Lyu et al., 2023, Jiao et al., 2022, Karam et al., 2022, Ren et al., 2022, Zhuravlev et al., 2022, Gokhale et al., 2021, Gunaseelan et al., 2021, Hartwig et al., 2021, Lin et al., 2021, Liu et al., 2021, Chittoor-Vinod et al., 2020, Yalgin et al., 2020, Castells-Nobau et al., 2019, Gokhale et al., 2019, Maor et al., 2019, Massey et al., 2019, Fedotov et al., 2018, Lavoy et al., 2018, Tran et al., 2018, Zlatic et al., 2018, Jang et al., 2017, Ng et al., 2017, Sitaraman et al., 2017, Maor et al., 2016, Bai and Sehgal, 2015, Ray and Lakhotia, 2015, Shih et al., 2015, Bingol et al., 2014, Zhu et al., 2013, Munoz-Soriano et al., 2012, Ng et al., 2012, Ruiz et al., 2012, Zhou et al., 2012, Kaun et al., 2011, Riemensperger et al., 2011, Lawal et al., 2010, Lacin et al., 2009, Venkiteswaran and Hasan, 2009, Yew et al., 2009, Jia et al., 2008, Park et al., 2008, Sitaraman et al., 2008, Dierick and Greenspan, 2007, Llorens et al., 2007, Muñoz-Soriano and Paricio, 2007, Periquet et al., 2007, Wang et al., 2007, Chang et al., 2006, Kontopoulos et al., 2006, Walker et al., 2006, Wang et al., 2006, Andretic et al., 2005, Auluck et al., 2005, Cha et al., 2005, Yang et al., 2005, Suster et al., 2004, Monastirioti, 2003, Suster et al., 2003, Yang et al., 2003, Auluck et al., 2002, Haywood et al., 2002, Feany and Bender, 2000)
Ddc-Gal4 (HL8.6)
Dopa Decarboxylase-GAL4
P[ddc-Gal4.L]
P{w+mC=Ddc-GAL4.L}
P{w[+mC]=Ddc-GAL4.L}
decarboxylase-GAL4
dihydroxyphenylalanine decarboxylase (ddc)-GAL4
dopa decarboxylase (ddc)-GAL4
pDdc-GAL4
Secondary FlyBase IDs
    References (200)