FlyBase Allele Report: Dmel\Rho1[E3.10]

General Information

Symbol

Dmel\Rho1^E3.10

Species

D. melanogaster

Name

FlyBase ID

FBal0090396

Feature type

allele

Associated gene

Dmel\Rho1

Associated Insertion(s)

Carried in Construct

Also Known As

RhoA^E3.10

Key Links

Genomic Maps

JBrowse

Allele class

loss of function allele

Mutagen

Nature of the Allele

Allele class

loss of function allele

(Halsell et al., 2000)

Mutagen

Progenitor genotype

Cytology

Description

Nucleotide substitution: G?C. Amino acid replacement: C189Y.

(Halsell et al., 2000)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

2R:16,106,038..16,106,038 [+]

Nucleotide change:

G16106038A

Reported nucleotide change:

G?A

Amino acid change:

Reported amino acid change:

C189Y

(Halsell et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Rho1^12-6)

(Bayer et al., 2003)

lethal | recessive

(Halsell and Kiehart, 1998)

lethal - all die during embryonic stage

(Sepp and Auld, 2003)

lethal - all die during embryonic stage | recessive

(Halsell et al., 2000)

some die during embryonic stage

(Sepp and Auld, 2003)

some die during embryonic stage | recessive

(Halsell et al., 2000)

Phenotype Manifest In

Detailed Description

Statement

Reference

Dorsal closure occurs slowly in mutant embryos.

(Rodriguez-Diaz et al., 2008)

Heterozygotes have wild-type leg and wing morphology.

(Bayer et al., 2003)

Homozygous and Rho1^E3.10/Rho1^J3.8 embryos have dorsal anterior holes in their cuticle. The hole extends from the anterior to approximately the second or third thoracic segment. The head skeleton may be extruded out of the dorsal opening. Homozygous embryos show compacted posterior spiracles with kinked filzkorper. Rho1^E3.10/Rho1^72O embryos have dorsal anterior holes in their cuticle. The embryos have compacted posterior spiracles.

(Halsell et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Rho1^E3.10/Rho1[+] is an enhancer of visible phenotype of br¹

(Ward et al., 2003)

NOT Enhancer of

Statement

Reference

Rho1^E3.10/Rho1[+] is a non-enhancer of abnormal neuroanatomy phenotype of PsGEF^Δ21

(Higuchi et al., 2009)

Rho1^E3.10/Rho1[+] is a non-enhancer of visible | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

Rho1^E3.10 is a non-enhancer of abnormal neuroanatomy phenotype of Scer\GAL4^GMR.PF, msn^EP549

(Ruan et al., 2002)

Suppressor of

Statement

Reference

Rho1^E3.10/Rho1[+] is a suppressor | partially of abnormal cell polarity | recessive | somatic clone phenotype of flw^FP41

(Sun et al., 2011)

Rho1^E3.10/Rho1[+], Scer\GAL4^dpp.blk1 is a suppressor of increased cell death phenotype of Moe^{RNAi.327-775.UAS}, Scer\GAL4^dpp.blk1

(Neisch et al., 2010)

Rho1^E3.10 is a suppressor of lethal | male phenotype of flw⁶

(Vereshchagina et al., 2004)

Rho1^E3.10 is a suppressor of lethal | recessive | larval stage phenotype of Moe^G0323

(Speck et al., 2003)

NOT Suppressor of

Statement

Reference

Rho1^E3.10 is a non-suppressor of visible | adult stage phenotype of Scer\GAL4^GMR.PFa, egr^UAS.cMa

(Ruan et al., 2016)

Rho1^E3.10/Rho1[+] is a non-suppressor of visible | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

Rho1^E3.10 is a non-suppressor of abnormal neuroanatomy phenotype of Scer\GAL4^GMR.PF, msn^EP549

(Ruan et al., 2002)

Other

Statement

Reference

Rho1^E3.10, stan[+]/stan^E59 has abnormal neuroanatomy | third instar larval stage phenotype

(Matsubara et al., 2011)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{R1171C.UAS.GFP} has visible phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{D1430N.UAS.GFP} has visible phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{D1847K.UAS.GFP} has visible phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{R1939X.UAS.GFP} has visible phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Sb^sbd-201/Sb^sbd-2 has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Rok¹ has visible | dominant phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], RhoGEF2^11-3 has visible | dominant phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], RhoGEF2^11-3 has partially lethal phenotype

(Bayer et al., 2003)

E(zip)12-5^12-5, Rho1^E3.10/Rho1[+] has visible | dominant phenotype

(Bayer et al., 2003)

E(zip)12-5^12-5, Rho1^E3.10/Rho1[+] has partially lethal phenotype

(Bayer et al., 2003)

E(zip)18-5^18-5, Rho1^E3.10/Rho1[+] has visible | dominant phenotype

(Bayer et al., 2003)

E(zip)18-5^18-5, Rho1^E3.10/Rho1[+] has partially lethal phenotype

(Bayer et al., 2003)

Df(3R)sbd105/+, Rho1^E3.10 has visible | dominant phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Rok¹ has partially lethal phenotype

(Bayer et al., 2003)

Rho1^E3.10, br¹ has visible | cold sensitive phenotype

(Bayer et al., 2003)

E(zip)12-5[+]/E(zip)12-5^12-5, Rho1^E3.10 has visible phenotype

(Bayer et al., 2003)

E(zip)18-5[+]/E(zip)18-5^18-5, Rho1^E3.10 has visible phenotype

(Bayer et al., 2003)

E(zip)31-6^31-6/E(zip)31-6[+], Rho1^E3.10 has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, RhoGEF2⁰⁴²⁹¹/RhoGEF2[+] has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, RhoGEF2^1.1/RhoGEF2[+] has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, RhoGEF2^11-3/RhoGEF2[+] has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, RhoGEF2^4.1/RhoGEF2[+] has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb^63b/Sb[+] has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb[+]/Sb⁷⁰ has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb[+]/Sb^Spi has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb^sbd-1/Sb^sbd-201 has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb^sbd-201/Sb^sbd-2 has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, rok[+]/Rok¹ has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, rok[+]/Rok² has visible phenotype

(Bayer et al., 2003)

Rho1^E3.10, zip^33-1/zip[+] has visible phenotype

(Bayer et al., 2003)

E(zip)31-6^31-6, Rho1^E3.10/Rho1[+] has visible | dominant phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], RhoGEF2⁰⁴²⁹¹ has visible | dominant phenotype

(Bayer et al., 2003)

E(zip)31-6^31-6, Rho1^E3.10/Rho1[+] has partially lethal phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], RhoGEF2^1.1 has visible | dominant phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], RhoGEF2^4.1 has visible | dominant phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Sb^63b has visible | dominant phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Sb⁷⁰ has visible | dominant phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Sb^Spi has visible | dominant phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], br¹ has visible | cold sensitive phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Rok² has visible | dominant phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], zip^33-1 has visible | dominant phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Sb^sbd-1/Sb^sbd-201 has visible phenotype

(Bayer et al., 2003)

E(br)121^Ebr121, Rho1^E3.10/Rho1[+] has visible | dominant phenotype

(Ward et al., 2003)

E(br)24^Ebr24, Rho1^E3.10/Rho1[+] has visible | dominant phenotype

(Ward et al., 2003)

E(br)121^Ebr121/E(br)121[+], Rho1^E3.10 has visible phenotype

(Ward et al., 2003)

E(br)24[+]/E(br)24^Ebr24, Rho1^E3.10 has visible phenotype

(Ward et al., 2003)

Rho1^E3.10, zip[+]/zip^Ebr has visible | dominant phenotype

(Halsell et al., 2000, Halsell and Kiehart, 1998)

Rho1^E3.10, zip[+]/zip^Ebr has partially lethal - majority die | dominant phenotype

(Halsell et al., 2000)

Df(2R)Jp1/+, Rho1^E3.10 has visible | dominant phenotype

(Halsell et al., 2000)

Rho1^E3.10, zip^Ebr has visible | dominant phenotype

(Halsell et al., 2000)

Rho1^E3.10, zip^Ebr has partially lethal - majority die | dominant phenotype

(Halsell et al., 2000)

Rho1^E3.10, zip[+]/zip^Ebr has partially lethal - majority live phenotype

(Halsell and Kiehart, 1998)

Rho1^E3.10/Rho1[+], zip^Ebr has visible | dominant phenotype

(Halsell and Kiehart, 1998)

Rho1^E3.10/Rho1[+], zip^Ebr has partially lethal - majority die | dominant phenotype

(Halsell and Kiehart, 1998)

Phenotype Manifest In

Enhancer of

Statement

Reference

Rho1^E3.10 is an enhancer of lamina | third instar larval stage phenotype of Scer\GAL4^GMR.PF, Sema1a^UAS.cYa

(Yu et al., 2010)

Rho1^E3.10 is an enhancer of eye photoreceptor cell | third instar larval stage phenotype of Scer\GAL4^GMR.PF, Sema1a^UAS.cYa

(Yu et al., 2010)

Rho1^E3.10/Rho1[+] is an enhancer of wing hair | increased number phenotype of Scer\GAL4^ap-md544, trc^T453A.UAS.L

(He et al., 2005)

Rho1^E3.10/Rho1[+] is an enhancer of leg phenotype of br¹

(Ward et al., 2003)

NOT Enhancer of

Statement

Reference

Rho1^E3.10/Rho1[+] is a non-enhancer of adult mushroom body alpha-lobe phenotype of PsGEF^Δ21

(Higuchi et al., 2009)

Rho1^E3.10/Rho1[+] is a non-enhancer of eye | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

Rho1^E3.10 is a non-enhancer of photoreceptor cell & axon phenotype of Scer\GAL4^GMR.PF, msn^EP549

(Ruan et al., 2002)

Suppressor of

Statement

Reference

Rho1^E3.10 is a suppressor of perineurium | embryonic stage phenotype of Pka-C1^B3

(Li et al., 2021)

Rho1^E3.10/Rho1[+] is a suppressor | partially of oocyte | somatic clone phenotype of flw^FP41

(Sun et al., 2011)

Rho1^E3.10/Rho1[+], Scer\GAL4^dpp.blk1 is a suppressor of wing disc | third instar larval stage phenotype of Moe^{RNAi.327-775.UAS}, Scer\GAL4^dpp.blk1

(Neisch et al., 2010)

NOT Suppressor of

Statement

Reference

Rho1^E3.10 is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PFa, egr^UAS.cMa

(Ruan et al., 2016)

Rho1^E3.10/Rho1[+] is a non-suppressor of eye | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

Rho1^E3.10 is a non-suppressor of photoreceptor cell & axon phenotype of Scer\GAL4^GMR.PF, msn^EP549

(Ruan et al., 2002)

Other

Statement

Reference

Rho1^E3.10, stan[+]/stan^E59 has dendrite | third instar larval stage phenotype

(Matsubara et al., 2011)

Rho1^E3.10, stan[+]/stan^E59 has larval dorsal multidendritic neuron ddaC | third instar larval stage phenotype

(Matsubara et al., 2011)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{R1171C.UAS.GFP} has wing phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{R1171C.UAS.GFP} has leg phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{D1430N.UAS.GFP} has wing phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{D1430N.UAS.GFP} has leg phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{D1847K.UAS.GFP} has wing phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{D1847K.UAS.GFP} has leg phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{R1939X.UAS.GFP} has wing phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Scer\GAL4^en-e16E, zip², zip^{R1939X.UAS.GFP} has leg phenotype

(Franke et al., 2007)

Rho1^E3.10/Rho1[+], Sb^sbd-1/Sb^sbd-201 has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Sb^sbd-201/Sb^sbd-2 has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Rok¹ has wing phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Rok¹ has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], RhoGEF2^11-3 has wing phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], RhoGEF2^11-3 has leg phenotype

(Bayer et al., 2003)

E(zip)12-5^12-5, Rho1^E3.10/Rho1[+] has wing phenotype

(Bayer et al., 2003)

E(zip)12-5^12-5, Rho1^E3.10/Rho1[+] has leg phenotype

(Bayer et al., 2003)

E(zip)18-5^18-5, Rho1^E3.10/Rho1[+] has wing phenotype

(Bayer et al., 2003)

E(zip)18-5^18-5, Rho1^E3.10/Rho1[+] has leg phenotype

(Bayer et al., 2003)

Df(3R)sbd105/+, Rho1^E3.10 has leg phenotype

(Bayer et al., 2003)

E(zip)12-5^12-5, Rho1^E3.10 has wing phenotype

(Bayer et al., 2003)

E(zip)12-5^12-5, Rho1^E3.10 has leg phenotype

(Bayer et al., 2003)

E(zip)18-5^18-5, Rho1^E3.10 has wing phenotype

(Bayer et al., 2003)

E(zip)18-5^18-5, Rho1^E3.10 has leg phenotype

(Bayer et al., 2003)

E(zip)31-6^31-6, Rho1^E3.10 has wing phenotype

(Bayer et al., 2003)

E(zip)31-6^31-6, Rho1^E3.10 has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10, RhoGEF2^11-3 has wing phenotype

(Bayer et al., 2003)

Rho1^E3.10, RhoGEF2^11-3 has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10, Rok¹ has wing phenotype

(Bayer et al., 2003)

Rho1^E3.10, Rok¹ has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10, br¹ has leg | cold sensitive phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb^sbd-1/Sb^sbd-201 has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb^sbd-201/Sb^sbd-2 has leg phenotype

(Bayer et al., 2003)

E(zip)31-6^31-6, Rho1^E3.10/Rho1[+] has wing phenotype

(Bayer et al., 2003)

Rho1^E3.10, RhoGEF2⁰⁴²⁹¹ has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10, RhoGEF2^1.1 has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10, RhoGEF2^4.1 has wing phenotype

(Bayer et al., 2003)

Rho1^E3.10, RhoGEF2^4.1 has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb^63b has wing phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb^63b has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb⁷⁰ has wing phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb⁷⁰ has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10, Sb^Spi has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10, Rok² has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10, zip^33-1 has leg phenotype

(Bayer et al., 2003)

E(zip)31-6^31-6, Rho1^E3.10/Rho1[+] has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], RhoGEF2⁰⁴²⁹¹ has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], RhoGEF2^1.1 has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], RhoGEF2^4.1 has wing phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], RhoGEF2^4.1 has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Sb^63b has wing phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Sb^63b has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Sb⁷⁰ has wing phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Sb⁷⁰ has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Sb^Spi has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], br¹ has leg | cold sensitive phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], Rok² has leg phenotype

(Bayer et al., 2003)

Rho1^E3.10/Rho1[+], zip^33-1 has leg phenotype

(Bayer et al., 2003)

E(br)121^Ebr121, Rho1^E3.10/Rho1[+] has leg phenotype

(Ward et al., 2003)

E(br)121^Ebr121, Rho1^E3.10 has leg phenotype

(Ward et al., 2003)

E(br)24^Ebr24, Rho1^E3.10 has leg phenotype

(Ward et al., 2003)

E(br)24^Ebr24, Rho1^E3.10/Rho1[+] has leg phenotype

(Ward et al., 2003)

Rho1^E3.10, zip[+]/zip^Ebr has femur phenotype

(Halsell et al., 2000, Halsell and Kiehart, 1998)

Rho1^E3.10, zip[+]/zip^Ebr has tibia phenotype

(Halsell et al., 2000, Halsell and Kiehart, 1998)

Rho1^E3.10, zip[+]/zip^Ebr has wing phenotype

(Halsell et al., 2000)

Rho1^E3.10, zip[+]/zip^Ebr has leg phenotype

(Halsell et al., 2000)

Rho1^E3.10, zip^Ebr has wing phenotype

(Halsell et al., 2000)

Rho1^E3.10, zip^Ebr has leg phenotype

(Halsell et al., 2000)

Rho1^E3.10, zip^Ebr has femur phenotype

(Halsell et al., 2000)

Rho1^E3.10, zip^Ebr has tibia phenotype

(Halsell et al., 2000)

Rho1^E3.10/Rho1[+], zip^Ebr has femur phenotype

(Halsell and Kiehart, 1998)

Rho1^E3.10/Rho1[+], zip^Ebr has tibia phenotype

(Halsell and Kiehart, 1998)

Additional Comments

Genetic Interactions

Statement

Reference

The dot-like small eye phenotype characteristic for flies expressing egr^Scer\UAS.cMa under the control of Scer\GAL4^GMR.PFa cannot be suppressed by combination with Rho1^E3.10 in heterozygous state.

(Ruan et al., 2016)

stan^E59/Rho1^E3.10 double heterozygous larvae show increased crossing of dendrites in the dendritic arbor of the ddaC class IV neurons compared to wild type (neither single heterozygote shows this phenotype).

(Matsubara et al., 2011)

One copy of Rho1^E3.10 partially suppresses the oocyte polarity defects seen when the posterior follicle cells are mutant for flw^FP41.

(Sun et al., 2011)

Rho1^E3.10/+ suppresses the ectopic apoptosis in wing disc cells expressing Moe^{dsRNA.327-775.Scer\UAS} under the control of Scer\GAL4^dpp.blk1.

(Neisch et al., 2010)

A Rho1^E3.10 background significantly enhances the Sema-1a^Scer\UAS.cYa overexpression-induced hyperfasciculation phenotype.

(Yu et al., 2010)

Heterozygosity for Rho1^E3.10 has no effect on the phenotype in the alpha lobes of the mushroom bodies that is seen in PsGEF^Δ21 animals.

(Higuchi et al., 2009)

Many adults expressing zip^{R1171C.Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^en-e16E in a zip²/+ ; Rho1^E3.10/+ background show both leg and wing abnormalities (26%), while others show wing abnormalities only (56%).

Some adults expressing zip^{D1430N.Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^en-e16E in a zip²/+ ; Rho1^E3.10/+ background show both leg and wing abnormalities (11%), while others show wing abnormalities only (5.4%).

Some adults expressing zip^{D1847K.Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^en-e16E in a zip²/+ ; Rho1^E3.10/+ background show both leg and wing abnormalities (8.2%).

Some adults expressing zip^{R1933X.Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^en-e16E in a zip²/+ ; Rho1^E3.10/+ background show both leg and wing abnormalities (14%), while others show wing abnormalities only (4.7%).

(Franke et al., 2007)

A Rho1^E3.10/+ background enhances the splitting wing hair phenotype of flies that express trc^{T453A.Scer\UAS} under the control of Scer\GAL4^ap-md544.

(He et al., 2005)

Rho1^E3.10/+ ; Sb^63b/+ flies have crumpled wings. Rho1^E3.10 shows a strong interaction (at least 50% of double heterozygotes have at least one malformed leg) with the following mutations: RhoGEF2^11-3, E(zip)12-5^12-5, E(zip)18-5^18-5, E(zip)31-6^31-6, zip^33-1, Sb^63b and Sb⁷⁰. Rho1^E3.10 shows a moderate interaction (25-49% of double heterozygotes have at least one malformed leg) with the following mutations: Df(3R)sbd105. Rho1^E3.10 shows a weak interaction (5-24% of double heterozygotes have at least one malformed leg) with the following mutations: Sb^Spi. Rho1^E3.10 shows no interaction with sqh^unspecified (assayed in terms of a malformed leg phenotype). Rho1^E3.10 shows a strong interaction (at least 50% of double heterozygotes have at least one malformed wing) with the following mutations: RhoGEF2^11-3, E(zip)12-5^12-5, E(zip)18-5^18-5, E(zip)31-6^31-6, rok¹, Sb^63b and Sb⁷⁰. Rho1^E3.10 shows a moderate interaction (25-49% of double heterozygotes have at least one malformed wing) with the following mutations: RhoGEF2^4.1. Sb^sbd-201/Sb^sbd-1 shows a strong interaction (at least 50% of double mutants have at least one malformed leg) with the following mutations: Rho1^E3.10/+.

(Bayer et al., 2003)

Dominantly enhances the frequency of br¹ mutant animals with malformed legs. The fraction of flies showing a malformed leg phenotype in at least one leg, for Rho1^E3.10 in double heterozygous combination with one of the following alleles is - Sb^Ebr20 : 11%, Sb^Ebr48 : 8%, Sb^Ebr228 : 2%, Sb^Ebr448 : 9%, Sb^Ebr536 : 14%, Sb^Ebr623 : 2%, bs^Ebr292 : 0%, E(br)24^Ebr24 : 23%, E(br)65^Ebr65 : 16%, E(br)155^Ebr155 : 16%, E(br)165^Ebr165 : 10%, E(br)333^Ebr333 : 5%, E(br)72^Ebr72 : 6%, E(br)121^Ebr121 : 37%, E(br)160^Ebr160 : 4%, E(br)187^Ebr187 : 0%, E(br)420^Ebr420 : 1% and E(br)444^Ebr444 : 6%.

(Ward et al., 2003)

The phenotype caused by expression of msn^EP549 under the control of Scer\GAL4^GMR.PF is not modified by the addition of Rho1^E3.10.

(Ruan et al., 2002)

100% of Rho1^E3.10/zip^Ebr double heterozygotes have a malformed leg phenotype, which shows variable expressivity. In more severe cases, a dent and twisting of the femur is apparent, along with shortening and thickening of the tibia. Notching of the posterior region of the wing blade is also seen. 42% of Rho1^E3.10/Df(2R)Jp1 double heterozygotes show a malformed phenotype.

(Halsell et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Rho1^12-6

(Bayer et al., 2003)

Rho1^Ebr233

(Ward et al., 2003)

Rho1^Ebr246

(Ward et al., 2003)

Rho1^J3.8

(Halsell et al., 2000)

Rho1^72F

(Halsell et al., 2000)

Rho1^72O

(Halsell et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

86545

w^a N^fa-g; Rho1^E3.10/CyO

Kyoto

106895

w^a N^fa-g; Rho1^E3.10/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

E3.10

(Halsell and Kiehart, 1998)

Rho1^E3,10

(Vereshchagina et al., 2004)

Rho1^E3.10

(Li et al., 2021, Chang et al., 2016, Ruan et al., 2016, Neisch et al., 2010, Yu et al., 2010, Brodu and Casanova, 2006, He et al., 2005)

RhoA^E3.10

(Matsubara et al., 2011, Rodriguez-Diaz et al., 2008, Franke et al., 2007, Wilk et al., 2004, Bayer et al., 2003, Halsell et al., 2000)

Rhoe3.10

(Sun et al., 2011)

l(2)52Fa^E3.10

rho1^E3.10

(Higuchi et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (23)

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