FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nejUAS.cMa
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General Information
Symbol
Dmel\nejUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Marek
FlyBase ID
FBal0104980
Feature type
allele
Associated gene
Dmel\nej
Associated Insertion(s)
Carried in Construct
P{UAS-nej.M}
Also Known As
UAS-dCBP
Key Links
Transgenic product class
wild_type
(Marek et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Marek et al., 2000)
Mutagen
in vitro construct
(Marek et al., 2000)
Progenitor genotype
Carried in construct
P{UAS-nej.M}
Cytology
Description

UAS regulatory sequences drive expression of the complete nej open reading frame.

(Marek et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
nej
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When nejScer\UAS.cMa is driven by Scer\GAL4OK386, an uninflated wing phenotype is seen. When driven by Scer\GAL4OK363, uninflated, partially folded, or curly wings (40%) some animals die as pharate adults. When driven by Scer\GAL430A animals die as pharate adults. When nejScer\UAS.cMa is driven by Scer\GAL471B most animals die as pharate adults survivors are minute or wild-type. When driven in the eye by Scer\GAL4GMR.PU, a smooth eye phenotype is seen.

      (Bantignies et al., 2000)

      Overexpression of nejScer\UAS.cMa under the control of Scer\GAL4elav.PLu in a wild-type background results in an approximately 70% decrease in presynaptic transmitter release at the neuromuscular junction, without any change quantal size and without any change in the average resting potential or average input resistance of the postsynaptic muscle. Overexpression of nejScer\UAS.cMa under the control of Scer\GAL4Mhc.PW in a wild-type background results in a decrease in presynaptic transmitter release at the neuromuscular junction. No changes in quantal size or muscle physiological parameters are seen.

      (Marek et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by Df(2R)cn9

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by Df(3L)VW3

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by Df(3L)kto2

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by Df(3L)vin7

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by In(2LR)DTD16LDTD42R

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by In(3R)Ubx7LLatsR

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by Pka-R1BDK.UAS

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by ash11

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by ash122

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible | partially by ash111

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by Df(2L)s1402

      (Bantignies et al., 2000)

      Scer\GAL4GMR.PU, nejUAS.cMa has eye phenotype, suppressible by Df(2L)C144

      (Bantignies et al., 2000)

      Scer\GAL4GMR.PU, nejUAS.cMa has eye phenotype, suppressible by Df(3L)vin7

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by Df(2L)C144

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by Df(2R)AA21

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, suppressible by Df(2R)ES1

      (Bantignies et al., 2000)
      NOT suppressed by
      Statement
      Reference

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, non-suppressible by Df(3L)brm11

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, non-suppressible by Df(3L)fz-M21

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, non-suppressible by Pc1

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, non-suppressible by ash114

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, non-suppressible by ash129

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, non-suppressible by ash21

      (Bantignies et al., 2000)

      Scer\GAL4OK386, nejUAS.cMa has wing phenotype, non-suppressible by trxE2/brm2

      (Bantignies et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      nejScer\UAS.cMa
      nejUAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Marek
      (Marek et al., 2000)
      Secondary FlyBase IDs
        References (2)