FlyBase Allele Report: Dmel\mir-137[CR]

General Information

Symbol

Dmel\mir-137^CR

Species

D. melanogaster

Name

FlyBase ID

FBal0401108

Feature type

allele

Associated gene

Dmel\mir-137

Associated Insertion(s)

TI{TI}mir-137^CR

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Saedi et al., 2024)

Mutagen

CRISPR/Cas9

(Saedi et al., 2024)

Progenitor genotype

Associated Insertion(s)

TI{TI}mir-137^CR

Cytology

Description

mir-137 is replaced by a Disc\RFP^{DsRed.3xP3.cUa} marker.

(Saedi et al., 2024)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

eye

(Padma et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

mir-137^CR has abnormal starvation stress response | adult stage | semidominant phenotype, enhanceable by Akh¹

(Saedi et al., 2024)

NOT Enhanced by

Statement

Reference

mir-137^CR has abnormal starvation stress response | adult stage | semidominant phenotype, non-enhanceable by Scer\GAL4^elav-C155/Akt^GD1361

(Saedi et al., 2024)

mir-137^CR has abnormal starvation stress response | adult stage | semidominant phenotype, non-enhanceable by Scer\GAL4^elav-C155/Pi3K92E^A2860C.UAS

(Saedi et al., 2024)

mir-137^CR has abnormal starvation stress response | adult stage | semidominant phenotype, non-enhanceable by Scer\GAL4^elav-C155/InR^K1409A.UAS

(Saedi et al., 2024)

mir-137^CR has abnormal starvation stress response | adult stage | semidominant phenotype, non-enhanceable by Scer\GAL4^elav-C155/InR^GD104

(Saedi et al., 2024)

Suppressed by

Statement

Reference

mir-137^CR has abnormal starvation stress response | semidominant | adult stage phenotype, suppressible by Scer\GAL4^elav-C155/Ptp61F^HMS00421

(Saedi et al., 2024)

mir-137^CR has decreased rate of adult locomotory behavior phenotype, suppressible by Scer\GAL4^elav-C155/Ptp61F^HMS00421

(Saedi et al., 2024)

mir-137^KO/mir-137^CR has increased body weight | adult stage phenotype, suppressible | partially by Scer\GAL4^elav-C155/Ptp61F^HMS00421

(Saedi et al., 2024)

mir-137^KO/mir-137^CR has abnormal starvation stress response | adult stage phenotype, suppressible by Scer\GAL4^elav-C155/Ptp61F^HMS00421

(Saedi et al., 2024)

mir-137^KO/mir-137^CR has decreased rate of adult locomotory behavior phenotype, suppressible by Scer\GAL4^elav-C155/Ptp61F^HMS00421

(Saedi et al., 2024)

mir-137^CR has abnormal starvation stress response | semidominant | adult stage phenotype, suppressible by Scer\GAL4^elav-C155/Ilp2^UAS.cBa

(Saedi et al., 2024)

mir-137^CR has abnormal starvation stress response | semidominant | adult stage phenotype, suppressible by Scer\GAL4^elav-C155/Ilp5^UAS.cUa

(Saedi et al., 2024)

mir-137^CR has abnormal starvation stress response | semidominant | adult stage phenotype, suppressible by Scer\GAL4^Ilp2.PR/Ilp2^UAS.cBa

(Saedi et al., 2024)

mir-137^CR has abnormal starvation stress response | semidominant | adult stage phenotype, suppressible by Scer\GAL4^elav-C155/Pi3K92E^UAS.Exel

(Saedi et al., 2024)

mir-137^KO/mir-137^CR has abnormal starvation stress response | adult stage phenotype, suppressible by Scer\GAL4^arm.PS/Ptp61F^HMS00421

(Saedi et al., 2024)

mir-137^CR has abnormal starvation stress response | adult stage phenotype, suppressible by Ptp61F^HMS00421/Scer\GAL4^r4

(Saedi et al., 2024)

mir-137^KO/mir-137^CR has increased body weight | adult stage phenotype, suppressible by Scer\GAL4^arm.PS/Ptp61F^HMS00421

(Saedi et al., 2024)

mir-137^CR has increased body weight | adult stage phenotype, suppressible by Scer\GAL4^elav-C155/Ptp61F^HMS00421

(Saedi et al., 2024)

NOT suppressed by

Statement

Reference

mir-137^CR has abnormal starvation stress response | semidominant | adult stage phenotype, non-suppressible by InR^A1325D.UAS/Scer\GAL4^InR.PU

(Saedi et al., 2024)

mir-137^CR has increased body weight | adult stage phenotype, non-suppressible by Ptp61F^HMS00421/Scer\GAL4^r4

(Saedi et al., 2024)

Enhancer of

Statement

Reference

mir-137^CR is an enhancer of abnormal starvation stress response | adult stage phenotype of Akh¹

(Saedi et al., 2024)

NOT Enhancer of

Statement

Reference

mir-137^CR is a non-enhancer of abnormal starvation stress response | adult stage phenotype of Akt^GD1361, Scer\GAL4^elav-C155

(Saedi et al., 2024)

mir-137^CR is a non-enhancer of abnormal starvation stress response | adult stage phenotype of Pi3K92E^A2860C.UAS, Scer\GAL4^elav-C155

(Saedi et al., 2024)

mir-137^CR is a non-enhancer of abnormal starvation stress response | adult stage phenotype of InR^K1409A.UAS, Scer\GAL4^elav-C155

(Saedi et al., 2024)

mir-137^CR is a non-enhancer of abnormal starvation stress response | adult stage phenotype of InR^GD104, Scer\GAL4^elav-C155

(Saedi et al., 2024)

Suppressor of

Statement

Reference

mir-137^CR is a suppressor | partially of abnormal starvation stress response | adult stage phenotype of InR^A1325D.UAS, Scer\GAL4^elav-C155

(Saedi et al., 2024)

mir-137^CR is a suppressor | partially of increased mortality phenotype of InR^A1325D.UAS, Scer\GAL4^elav-C155

(Saedi et al., 2024)

Other

Statement

Reference

Akt^UAS.ORF, Scer\GAL4^elav-C155, mir-137^CR has abnormal starvation stress response | adult stage phenotype

(Saedi et al., 2024)

InR^A1325D.UAS, Scer\GAL4^elav-C155, mir-137^CR has abnormal starvation stress response | adult stage phenotype

(Saedi et al., 2024)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

mir-137^CR is rescued by Scer\GAL4^elav-C155/mir-137^UAS.cUa

(Saedi et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

miR-137^CR

(Padma et al., 2025)

mir-137^CR

(Saedi et al., 2024)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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