FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\Cht2
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General Information
Symbol
Dmel\Cht2
Species
D. melanogaster
Name
Chitinase 2
Annotation Symbol
CG2054
Feature Type
protein_coding_gene
FlyBase ID
FBgn0022702
Gene Model Status
Current
Stock Availability
8 publicly available
Gene Summary
Contribute a Gene Snapshot for this gene.
All Summaries
Also Known As

DmCht2

Key Links
Genomic Location
Cytogenetic map
62B1-62B1
Sequence location
Recombination map
3-1.0
RefSeq locus
NT_037436 REGION:1752328..1755934
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (14 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables chitinase activity
inferred from mutant phenotype
(Behr and Riedel, 2020)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables chitin binding
inferred from electronic annotation with InterPro:IPR011583
(InterPro Project Members, 2004-)
enables chitinase activity
inferred from biological aspect of ancestor with PANTHER:PTN000126545
(GO Reference Genome Project, 2011-)
enables hydrolase activity, hydrolyzing O-glycosyl compounds
inferred from electronic annotation with InterPro:IPR001579
(InterPro Project Members, 2004-)
Biological Process (8 terms)
Terms Based on Experimental Evidence (7 terms)
CV Term
Evidence
References
involved_in chitin catabolic process
inferred from mutant phenotype
(Behr and Riedel, 2020)
involved_in chitin-based cuticle development
inferred from mutant phenotype
(Behr and Riedel, 2020, Pesch et al., 2016)
involved_in chitin-based embryonic cuticle biosynthetic process
inferred from mutant phenotype
(Pesch et al., 2016)
involved_in ecdysis, chitin-based cuticle
inferred from mutant phenotype
(Pesch et al., 2016)
involved_in larval chitin-based cuticle development
inferred from mutant phenotype
(Pesch et al., 2017)
involved_in regulation of tube size, open tracheal system
inferred from mutant phenotype
(Behr and Riedel, 2020)
involved_in wound healing
inferred from mutant phenotype
(Pesch et al., 2016)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in carbohydrate metabolic process
inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579
(InterPro Project Members, 2004-)
involved_in chitin catabolic process
inferred from biological aspect of ancestor with PANTHER:PTN000126545
(GO Reference Genome Project, 2011-)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
located_in external side of apical plasma membrane
inferred from direct assay
(Behr and Riedel, 2020)
located_in extracellular space
inferred from direct assay
(Pesch et al., 2017)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in extracellular region
inferred from biological aspect of ancestor with PANTHER:PTN000126545
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Pathway (FlyBase)
Protein Family (UniProt)
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. (Q9W092)
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
CHITINASES -
Chitinases belong to the 18-glycosylhydrolase family and possess one or more glyco18 domains. Chitinases hydrolyze the N-acetyl-β-D-glucosamine β-1,4 glycosidic bonds in chitin polymers. (Adapted from FBrf0230884).
Pathway (FlyBase)
CHITIN CATABOLISM -
Chitin is a linear homopolymer of N-acetyl-β-D-glucosamine residues linked by β-1,4 glycosidic bonds. It is a major structural component of the D. melanogaster exoskeleton, tracheal and internal tendon cuticles, and the intestinal peritrophic matrix. Chitin degradation is mediated by chitinases, which cleave chitin at random positions producing chitooligosaccharides, and β-N- acetylglucosaminidases, which catalyze the stepwise removal of terminal, nonreducing β-N-acetylglucosamine residues from chitooligosaccharides. Chitin degradation occurs, for example, during D. melanogaster molting and cuticle turnover. (Adapted from PMID:26982439.)
Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Cht2 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9W092)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.43

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.46

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Cht2-RA
FBtr0072795
NM_057950
1645
484
Cht2-RB
FBtr0305966
NM_001259621
2690
484
Cht2-RC
FBtr0334075
NM_001274353
1911
484
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Cht2-PA
FBpp0072677
54.1
484
5.69
Q9W092
NP_477298
AAF47562
Cht2-PB
FBpp0297108
54.1
484
5.69
Q9W092
NP_001246550
AFH04221
Cht2-PC
FBpp0306200
54.1
484
5.69
Q9W092
NP_001261282
AGB93977
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

484 aa isoforms: Cht2-PA, Cht2-PB, Cht2-PC
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cht2 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.39

Transcript Expression
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 13 -- 17
embryonic/larval foregut
(Pesch et al., 2017)
embryonic/larval hindgut
(Pesch et al., 2017)
embryonic stage 14 -- 17
embryonic/larval salivary gland
(Pesch et al., 2017)
larval tracheal system
(Pesch et al., 2017)
embryonic stage 17
embryonic/larval proventriculus
(Pesch et al., 2017)
embryonic/larval posterior spiracle
(Pesch et al., 2017)
embryonic/larval anterior spiracle
(Pesch et al., 2017)
embryonic/larval epidermis
(Pesch et al., 2017)
third instar larval stage
embryonic/larval salivary gland
(Pesch et al., 2017)
larval tracheal system

Comment: extracellular matrix of

(Pesch et al., 2017)
embryonic/larval foregut

Comment: extracellular matrix of

(Pesch et al., 2017)
embryonic/larval proventriculus

Comment: extracellular matrix of

(Pesch et al., 2017)
embryonic/larval posterior spiracle

Comment: extracellular matrix of

(Pesch et al., 2017)
imaginal disc
(Pesch et al., 2017)
embryonic/larval epidermis

Comment: extracellular matrix of

(Pesch et al., 2017)
embryonic/larval midgut

Comment: extracellular matrix of

(Pesch et al., 2017)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data

Cht2 protein expression is observed in the cuticle-forming organs of late embryos in the foregut, hindgut, tracheal system, epidermis, spriacles, and salivary glands. Cht2 protein is also observed in tissues that produce chitin matrices including the tracheal system, foregut, midgut, and posterior spiracles. Staining is also observed in small salivary gland cells and in imaginal disc cells. Cht2 protein is present in the newly synthesized chitin matrix of the assembly zone and in the compact chitin lamellae of the procuticle.

(Pesch et al., 2017)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in external side of apical plasma membrane
inferred from direct assay
(Behr and Riedel, 2020)
located_in extracellular space
inferred from direct assay
(Pesch et al., 2017)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Cht2 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 1-3
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 1 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Cht2
Transgenic constructs containing regulatory region of Cht2
Aberrations (Deficiencies and Duplications) ( 0 )
Inferred from experimentation ( 0 )
Inferred from location ( 4 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
partially lethal, with Scer\GAL469B
partially lethal - majority die, with Scer\GAL469B
partially lethal - majority live, with Scer\GAL4btl.PS
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4pnr-MD237
Other Phenotypes
Allele
abnormal body color, with Scer\GAL4pnr-MD237
abnormal eclosion, with Scer\GAL469B
abnormal wound healing, with Scer\GAL469B
increased size | embryonic stage, with Scer\GAL4btl.PS
majority die during larval stage, with Scer\GAL469B
some die during pupal stage, with Scer\GAL469B
Phenotype manifest in
Allele
assembly zone | third instar larval stage, with Scer\GAL469B
cuticular pore | third instar larval stage, with Scer\GAL469B
embryonic/larval cuticle, with Scer\GAL469B
embryonic/larval tracheal dorsal trunk, with Scer\GAL4btl.PS
embryonic/larval tracheal dorsal trunk | embryonic stage, with Scer\GAL4btl.PS
embryonic/larval tracheal dorsal trunk | embryonic stage, with Scer\GAL4btl.PU
embryonic/larval tracheal section | larval stage, with Scer\GAL4btl.PS
mesonotum, with Scer\GAL4pnr-MD237
procuticle | third instar larval stage, with Scer\GAL469B
pupal cuticle, with Scer\GAL469B
taenidial fold | embryonic stage, with Scer\GAL4btl.PS
taenidial fold | larval stage, with Scer\GAL4btl.PS
third instar larval cuticle, with Scer\GAL469B
tracheal dorsal trunk primordium | embryonic stage 15, with Scer\GAL4btl.PS
tracheal lumen | embryonic stage, with Scer\GAL4btl.PS
wing, with Scer\GAL469B
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (8)
Hsap\CHIA
7 of 14
Yes
No
1  
Hsap\CHI3L1
5 of 14
No
No
Hsap\CHIT1
5 of 14
No
No
Hsap\OVGP1
5 of 14
No
No
Hsap\CHI3L2
4 of 14
No
No
Hsap\CTBS
3 of 14
No
Yes
Hsap\CHID1
1 of 14
No
No
Hsap\USP49
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (8)
Rnor\RGD1309110
7 of 14
Yes
No
Rnor\Chi3l3
6 of 14
No
No
Rnor\Chia
6 of 14
No
No
Rnor\Chi3l1
4 of 14
No
No
Rnor\Chit1
4 of 14
No
No
Rnor\Ctbs
3 of 14
No
Yes
Rnor\Chid1
1 of 14
No
No
Rnor\Usp49
1 of 14
No
No
Mus musculus (laboratory mouse) (11)
Mmus\Chia1
7 of 14
Yes
No
Mmus\Chil4
7 of 14
Yes
No
Mmus\Chil6
7 of 14
Yes
No
Mmus\Chil3
6 of 14
No
No
Mmus\Chil5
6 of 14
No
No
Mmus\Chil1
5 of 14
No
No
Mmus\Chit1
5 of 14
No
No
Mmus\Ovgp1
5 of 14
No
No
Mmus\Ctbs
2 of 14
No
Yes
Mmus\Chid1
1 of 14
No
No
Mmus\Usp49
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (7)
Xtro\XB5763442
5 of 13
Yes
No
Xtro\chit1
4 of 13
No
No
Xtro\ctbs
2 of 13
No
Yes
Xtro\usp49
2 of 13
No
No
Xtro\arsj
1 of 13
No
No
Xtro\chia
1 of 13
No
Yes
Xtro\LOC100494478
1 of 13
No
Yes
Danio rerio (Zebrafish) (11)
Drer\chia.3
5 of 14
Yes
No
Drer\chia.4
5 of 14
Yes
No
Drer\chia.6
5 of 14
Yes
No
Drer\chia.1
4 of 14
No
No
Drer\chia.2
4 of 14
No
No
Drer\ovgp1
3 of 14
No
No
Drer\ctbs
2 of 14
No
Yes
Drer\si:ch211-226m16.2
2 of 14
No
No
Drer\chia.5
1 of 14
No
No
Drer\chid1
1 of 14
No
No
Drer\usp49
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (39)
Cele\cht-1
5 of 14
Yes
No
Cele\cht-4
5 of 14
Yes
No
Cele\chil-3
4 of 14
No
No
Cele\chil-4
4 of 14
No
No
Cele\chil-7
4 of 14
No
No
Cele\chil-15
4 of 14
No
No
Cele\chil-16
4 of 14
No
No
Cele\chil-17
4 of 14
No
No
Cele\chil-18
4 of 14
No
No
Cele\cht-2
4 of 14
No
No
Cele\chil-1
3 of 14
No
No
Cele\chil-2
3 of 14
No
No
Cele\chil-6
3 of 14
No
No
Cele\chil-8
3 of 14
No
No
Cele\chil-12
3 of 14
No
No
Cele\chil-13
3 of 14
No
No
Cele\chil-19
3 of 14
No
No
Cele\chil-21
3 of 14
No
No
Cele\chil-24
3 of 14
No
No
Cele\chil-25
3 of 14
No
No
Cele\chil-26
3 of 14
No
Yes
Cele\lmd-4
3 of 14
No
No
Cele\lmd-5
3 of 14
No
No
Cele\chil-5
2 of 14
No
No
Cele\chil-9
2 of 14
No
No
Cele\chil-11
2 of 14
No
No
Cele\chil-20
2 of 14
No
No
Cele\chil-22
2 of 14
No
No
Cele\chil-27
2 of 14
No
No
Cele\cht-3
2 of 14
No
Yes
Cele\R09D1.14
2 of 14
No
No
Cele\T19H5.6
2 of 14
No
No
Cele\btb-16
1 of 14
No
Yes
Cele\btb-17
1 of 14
No
Yes
Cele\btb-18
1 of 14
No
Yes
Cele\C45E5.3
1 of 14
No
Yes
Cele\chil-23
1 of 14
No
No
Cele\K08F9.3
1 of 14
No
No
Cele\T01C4.8
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (29)
Agam\AgaP_AGAP005634
12 of 12
Yes
Yes
Agam\AgaP_AGAP006086
7 of 12
No
Yes
Agam\AgaP_AGAP005337
6 of 12
No
No
Agam\AgaP_AGAP005339
6 of 12
No
No
Agam\AgaP_AGAP006414
6 of 12
No
No
Agam\AgaP_AGAP013260
6 of 12
No
Yes
Agam\AgaP_AGAP002457
5 of 12
No
No
Agam\AgaP_AGAP004876
5 of 12
No
No
Agam\AgaP_AGAP006898
5 of 12
No
No
Agam\AgaP_AGAP009049
5 of 12
No
No
Agam\AgaP_AGAP011033
5 of 12
No
No
Agam\AgaP_AGAP013120
5 of 12
No
Yes
Agam\AgaP_AGAP013166
5 of 12
No
Yes
Agam\AgaP_AGAP013496
5 of 12
No
Yes
Agam\AgaP_AGAP000198
4 of 12
No
No
Agam\AgaP_AGAP000436
4 of 12
No
No
Agam\AgaP_AGAP006191
4 of 12
No
No
Agam\AgaP_AGAP008566
4 of 12
No
Yes
Agam\AgaP_AGAP007182
3 of 12
No
No
Agam\AgaP_AGAP008060
3 of 12
No
No
Agam\AgaP_AGAP008061
3 of 12
No
No
Agam\AgaP_AGAP009022
3 of 12
No
No
Agam\AgaP_AGAP010371
3 of 12
No
No
Agam\AgaP_AGAP001863
2 of 12
No
No
Agam\AgaP_AGAP004831
2 of 12
No
Yes
Agam\AgaP_AGAP008561
2 of 12
No
No
Agam\AgaP_AGAP008562
2 of 12
No
No
Agam\AgaP_AGAP004367
1 of 12
No
No
Agam\AgaP_AGAP005975
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (9)
Atha\AT4G19720
11 of 13
Yes
Yes
Atha\AT4G19750
11 of 13
Yes
Yes
Atha\AT4G19760
11 of 13
Yes
Yes
Atha\AT4G19800
11 of 13
Yes
Yes
Atha\AT4G19820
11 of 13
Yes
Yes
Atha\ChiC
11 of 13
Yes
Yes
Atha\AT4G19730
10 of 13
No
No
Atha\AT4G19770
9 of 13
No
No
Atha\AT4G19740
8 of 13
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\CTS2
8 of 13
Yes
No
Schizosaccharomyces pombe (Fission yeast) (0)
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Cht2. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (17)
Cht4
9 of 13
Cht5
9 of 13
Cht8
9 of 13
Cht9
9 of 13
Cht7
8 of 13
Cht6
7 of 13
Cht11
7 of 13
Cht12
7 of 13
Cht10
6 of 13
Idgf4
5 of 13
Idgf6
5 of 13
Idgf3
4 of 13
Idgf1
3 of 13
Idgf2
3 of 13
Idgf5
3 of 13
Muc26B
1 of 13
Muc96D
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    CHIA; chitinase acidic
    7 of 14
    606080
         
        CHI3L1; chitinase 3 like 1
        5 of 14
        601525
        CHIT1; chitinase 1
        5 of 14
        600031
          OVGP1; oviductal glycoprotein 1
          5 of 14
          603578
              CHI3L2; chitinase 3 like 2
              4 of 14
              601526
                  CTBS; chitobiase
                  3 of 14
                  600873
                      Functional Complementation Data
                      Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                      Interactions
                      Summary of Physical Interactions
                      Interaction Browsers
                      Summary of Genetic Interactions
                      Interaction Browsers
                      Starting gene(s)
                      Interaction type
                      Interacting gene(s)
                      Reference
                      Starting gene(s)
                      Interaction type
                      Interacting gene(s)
                      Reference
                      External Data
                      Linkouts
                      BioGRID - A database of protein and genetic interactions.
                      DroID - A comprehensive database of gene and protein interactions.
                      Pathways
                      Signaling Pathways (FlyBase)
                      Metabolic Pathways
                      FlyBase
                      CHITIN CATABOLISM
                      External Links
                      KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.
                      External Data
                      Linkouts
                      KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
                      Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                      Class of Gene
                      Genomic Location and Detailed Mapping Data
                      Chromosome (arm)
                      3L
                      Recombination map
                      3-1.0
                      Cytogenetic map
                      62B1-62B1
                      Sequence location
                      FlyBase Computed Cytological Location
                      Cytogenetic map
                      Evidence for location
                      62B1-62B1
                      Limits computationally determined from genome sequence between P{EP}rhoEP3704&P{PZ}l(3)0622606226 and P{PZ}dlt04276
                      Experimentally Determined Cytological Location
                      Cytogenetic map
                      Notes
                      References
                      61F3-62B11
                      (determined by in situ hybridisation)
                      (BDGP Project Members, 1994-1999)
                      Experimentally Determined Recombination Data
                      Location

                      3-1.0

                      (FlyBase, 2016)

                      3-2.7

                      (Comeron et al., 2012)
                      Left of (cM)
                      Right of (cM)
                      Notes
                      Stocks and Reagents
                      Stocks (8)
                      Genomic Clones (20)
                      cDNA Clones (28)
                       

                      Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

                      cDNA clones, fully sequenced
                      BDGP DGC clones
                      Other clones
                      Drosophila Genomics Resource Center cDNA clones

                      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                      cDNA Clones, End Sequenced (ESTs)
                      BDGP DGC clones
                      Other clones
                      RNAi and Array Information
                      Linkouts
                      DRSC - Results frm RNAi screens
                      Antibody Information
                      Laboratory Generated Antibodies
                       

                      polyclonal

                      (Pesch et al., 2017)
                      Commercially Available Antibodies
                       
                      Cell Line Information
                      Publicly Available Cell Lines
                       
                        Other Stable Cell Lines
                         
                          Other Comments
                          Relationship to Other Genes
                          Source for database merge of
                          Additional comments
                          Nomenclature History
                          Source for database identify of

                          Source for identity of: Cht2 CG2054

                          (Deng, 1999.11)
                          Nomenclature comments
                          Etymology
                          Synonyms and Secondary IDs (9)
                          Datasets (0)
                          Study focus (0)
                          Experimental Role
                          Project
                          Project Type
                          Title
                          Study result (0)
                          Result
                          Result Type
                          Title
                          External Crossreferences and Linkouts ( 50 )
                          Sequence Crossreferences
                          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                          UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
                          UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
                          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                          Other crossreferences
                          AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
                          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                          DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
                          EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
                          FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
                          FlyMine - An integrated database for Drosophila genomics
                          InterPro - A database of protein families, domains and functional sites
                          KEGG Genes - Molecular building blocks of life in the genomic space.
                          MARRVEL_MODEL - MARRVEL (model organism gene)
                          Linkouts
                          BioGRID - A database of protein and genetic interactions.
                          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                          DroID - A comprehensive database of gene and protein interactions.
                          DRSC - Results frm RNAi screens
                          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                          Flygut - An atlas of the Drosophila adult midgut
                          iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                          KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.
                          KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
                          Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                          References (62)