FlyBase Gene Report: Dmel\krimp

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Gene: Dmel\krimp

General Information

Symbol

Dmel\krimp

Species

D. melanogaster

Name

krimper

Annotation Symbol

CG15707

Feature Type

protein_coding_gene

FlyBase ID

FBgn0034098

Gene Model Status

Stock Availability

8 publicly available

Gene Summary

Stable structural component of the perinuclear meiotic nuage, a germline-specific subcellular membraneless ribonucleoprotein compartment involved in production of transposable element-repressing Piwi-interacting RNA (piRNA)-induced silencing complexes (piRISCs), which are essential for maintaining germline integrity during oogenesis (PubMed:17428915, PubMed:26212455, PubMed:26295961). Scaffold component of the ping-pong piRNA processing (4P) complex that recruits the Piwi proteins aub and AGO3 to specific subregions of the nuage where it coordinates their activity in the ping-pong amplification step of secondary piRNA biogenesis (PubMed:26295961, PubMed:34210982). Binds methylated aub, which is associated with piRNA, and unmethylated AGO3, which is not associated with piRNA, bringing the Piwi proteins into close proximity and facilitating the loading of freshly cut piRNAs generated by aub onto AGO3 (PubMed:34210982). Promotes asymmetric ping-pong amplification by aub and AGO3 to bias production towards antisense piRNAs capable of silencing transposable elements (PubMed:26212455). Required for symmetrical dimethylation of AGO3, probably by recruitment to the nuage where methylosome components are located; dimethylation promotes AGO3 dissociation and interaction with other tudor-domain containing proteins such as tud (PubMed:26212455). Required for the recruitment of mael to the perinuclear meiotic nuage (PubMed:17428915). Required for the recruitment of aub to the nuage in testes but not in ovaries (PubMed:22303351). Involved in repression of long interspersed nuclear elements (LINEs) including HeT-A, I-element LINEs and possibly mst40, but not TART LINEs (PubMed:17428915). (UniProt, A1ZAC4)

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
UniProtKB
Interactive Fly

Also Known As

montecristo, mtc

Key Links

Genomic Location

Cytogenetic map

Sequence location

2R:16,238,103..16,240,722 [-]

Recombination map

2-79

RefSeq locus

NT_033778 REGION:16238103..16240722

Sequence

Get Decorated FASTA

Genomic Maps

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (8 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables metal ion binding

inferred from electronic annotation with InterPro:IPR000571

(InterPro Project Members, 2004-)

Biological Process (5 terms)

Terms Based on Experimental Evidence (5 terms)

CV Term

Evidence

References

involved_in negative regulation of oskar mRNA translation

inferred from mutant phenotype

(Lim and Kai, 2007)

involved_in oocyte dorsal/ventral axis specification

inferred from mutant phenotype

(Lim and Kai, 2007)

involved_in oocyte karyosome formation

inferred from mutant phenotype

(Barbosa et al., 2007, Lim and Kai, 2007)

involved_in secondary piRNA processing

inferred from physical interaction with FLYBASE:aub; FB:FBgn0000146,FLYBASE:AGO3; FB:FBgn0250816

(Huang et al., 2021)

inferred from mutant phenotype

(Olivieri et al., 2012)

involved_in transposable element silencing by piRNA-mediated mRNA destabilization

inferred from mutant phenotype

(Lim et al., 2009)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

is_active_in P granule

inferred from direct assay

(Vrettos et al., 2021, Huang et al., 2014, Lim et al., 2009)

located_in P granule

inferred from direct assay

(Webster et al., 2015, Patil and Kai, 2010, Lim and Kai, 2007)

inferred from direct assay

(Nagao et al., 2011)

located_in perinuclear region of cytoplasm

inferred from direct assay

(Lim and Kai, 2007)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

Protein Family (UniProt)

Belongs to the Tudor domain containing protein family. (A1ZAC4)

Protein Signatures (InterPro)

Summaries

Protein Function (UniProtKB)

Stable structural component of the perinuclear meiotic nuage, a germline-specific subcellular membraneless ribonucleoprotein compartment involved in production of transposable element-repressing Piwi-interacting RNA (piRNA)-induced silencing complexes (piRISCs), which are essential for maintaining germline integrity during oogenesis (PubMed:17428915, PubMed:26212455, PubMed:26295961). Scaffold component of the ping-pong piRNA processing (4P) complex that recruits the Piwi proteins aub and AGO3 to specific subregions of the nuage where it coordinates their activity in the ping-pong amplification step of secondary piRNA biogenesis (PubMed:26295961, PubMed:34210982). Binds methylated aub, which is associated with piRNA, and unmethylated AGO3, which is not associated with piRNA, bringing the Piwi proteins into close proximity and facilitating the loading of freshly cut piRNAs generated by aub onto AGO3 (PubMed:34210982). Promotes asymmetric ping-pong amplification by aub and AGO3 to bias production towards antisense piRNAs capable of silencing transposable elements (PubMed:26212455). Required for symmetrical dimethylation of AGO3, probably by recruitment to the nuage where methylosome components are located; dimethylation promotes AGO3 dissociation and interaction with other tudor-domain containing proteins such as tud (PubMed:26212455). Required for the recruitment of mael to the perinuclear meiotic nuage (PubMed:17428915). Required for the recruitment of aub to the nuage in testes but not in ovaries (PubMed:22303351). Involved in repression of long interspersed nuclear elements (LINEs) including HeT-A, I-element LINEs and possibly mst40, but not TART LINEs (PubMed:17428915).

(UniProt, A1ZAC4)

Summary (Interactive Fly)

a component of nuage in the germline that functions to repress selfish genetic elements - Aub and Ago3 are recruited to nuage to form a ping-pong complex assembled by Krimper - simultaneously binds the N-terminal regions of Aub and Ago3 to promote generation of new piRNA - Krimper enforces an antisense bias on piRNA pools by binding AGO3 in the Drosophila germline

Interactive Fly

Gene Model and Products

Number of Transcripts

1

Number of Unique Polypeptides

1

Please see the JBrowse view of Dmel\krimp for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry A1ZAC4)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

PDB - An information portal to biological macromolecular structures

Comments on Gene Model

Gene model reviewed during 5.50

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0087189

2549

746

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

FBpp0086333

84.0

746

5.16

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Subunit Structure (UniProtKB)

Homooligomerizes (via N-terminus) (PubMed:26295961). Component of the ping-pong piRNA processing (4P) complex consisting of krimp, aub and AGO3; a single molecule of krimp can bind both aub and AGO3 without the need for homooligomerization (PubMed:26295961, PubMed:34210982). Interacts (via canonical tudor domain) with aub (via N-terminus when symmetrically dimethylated on arginine residues) (PubMed:26295961, PubMed:34210982). Interacts (via non-canonical tudor domain) with AGO3 (via N-terminus when unmethylated on arginine residues); this interaction leads to symmetrical dimethylation on AGO3 arginine residues and its subsequent dissociation from krimp (PubMed:26212455, PubMed:26295961, PubMed:34210982). Krimp associated AGO3 is mostly free of piRNA binding and the interaction plays an important role in the loading of AGO3 with piRNAs; piRNA binding stimulates methylation of ACO3 by the csul/PRMT5 methylosome complex and promotes dissociation of the two proteins (PubMed:26212455, PubMed:26295961, PubMed:34210982).

(UniProt, A1ZAC4)

Domain

Possesses two tudor domains, a C-terminal canonical tudor domain and a central non-canonical tudor domain (Probable) (PubMed:34210982). Both tudor domains can interact with Piwi proteins allowing the simultaneous binding of aub and AGO3; this brings them in close proximity to facilitate their role in ping-pong ampification of piRNAs (PubMed:26295961, PubMed:34210982). The canonical tudor domain possesses a hydrophobic pocket that preferentially binds methylated aub; the interaction requires symmetrical methylation on at least one aub N-terminal arginine (PubMed:26295961, PubMed:34210982). The non-canonical tudor domain possesses a hydrophilic binding pocket that preferentially binds unmethylated AGO3; methylation on any of the AGO3 N-terminal arginines disrupts this interaction (PubMed:34210982). The differential binding preference ensures recruitment of one piRNA loaded (aub) and one unloaded (AGO3) Piwi-protein; the methylation state of the Piwi proteins acts as an indicator of their piRNA binding state (PubMed:34210982).

(UniProt, A1ZAC4)

Crossreferences

InterPro - A database of protein families, domains and functional sites

PDB - An information portal to biological macromolecular structures

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\krimp using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

krimp_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.09

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | female & oogenesis

female germline cell

• P granule

(Nagao et al., 2011)

adult stage | male & spermatogenesis

male germline cell

• P granule

(Nagao et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

is_active_in P granule

inferred from direct assay

(Vrettos et al., 2021, Huang et al., 2014, Lim et al., 2009)

located_in P granule

inferred from direct assay

(Webster et al., 2015, Patil and Kai, 2010, Lim and Kai, 2007)

inferred from direct assay

(Nagao et al., 2011)

located_in perinuclear region of cytoplasm

inferred from direct assay

(Lim and Kai, 2007)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\krimp in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\krimp

View exonic expression by tissue for Dmel\krimp

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0034098

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

36804/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0034098

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0034098

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0034098

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG15707

Flygut - An atlas of the Drosophila adult midgut

FBgn0034098

Images

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 6 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 11 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of krimp

Transgenic constructs containing regulatory region of krimp

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

(Lim and Kai, 2007, Ryder, 2004.4.26)

Inferred from location ( 8 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Sterility

Allele

female semi-sterile, with Scer\GAL4^{VP16.nanos.UTR}, Scer\GAL4^VP16.otu, Scer\GAL4^nanos.PG

krimp^RNAi.UAS.V22

female sterile (with Df(2R)Exel6063)

krimp^f06583

female sterile | recessive

krimp^f06583

Phenotype manifest in

Allele

egg chorion (with krimp^mtc-2)

krimp^mtc-3

egg chorion (with krimp^mtc-3)

krimp^mtc-2

egg chorion | germline clone

karyosome (with krimp^mtc-2)

krimp^mtc-3

karyosome (with krimp^mtc-3)

krimp^mtc-2

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (7)

3 of 14

Yes

No

3 of 14

Yes

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

1 of 14

No

No

1 of 14

No

No

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (7)

3 of 14

Yes

No

2 of 14

No

No

2 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

Mus musculus (laboratory mouse) (6)

2 of 14

Yes

No

2 of 14

Yes

No

2 of 14

Yes

No

2 of 14

Yes

No

1 of 14

No

No

1 of 14

No

No

Xenopus tropicalis (Western clawed frog) (6)

2 of 13

Yes

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

Danio rerio (Zebrafish) (9)

2 of 14

Yes

No

2 of 14

Yes

No

2 of 14

Yes

No

2 of 14

Yes

No

2 of 14

Yes

No

1 of 14

No

No

Drer\si:ch211-189e2.3

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

Caenorhabditis elegans (Nematode, roundworm) (2)

1 of 14

Yes

Yes

1 of 14

Yes

No

Anopheles gambiae (African malaria mosquito) (10)

Agam\AgaP_AGAP002475

6 of 12

Yes

Yes

Agam\AgaP_AGAP008268

2 of 12

No

No

Agam\AgaP_AGAP010722

2 of 12

No

No

Agam\AgaP_AGAP011089

2 of 12

No

No

Agam\AgaP_AGAP012340

2 of 12

No

No

Agam\AgaP_AGAP007965

1 of 12

No

No

Agam\AgaP_AGAP010171

1 of 12

No

No

Agam\AgaP_AGAP011088

1 of 12

No

No

Agam\AgaP_AGAP012831

1 of 12

No

No

1 of 12

No

No

Arabidopsis thaliana (thale-cress) (4)

1 of 13

Yes

No

1 of 13

Yes

No

1 of 13

Yes

No

1 of 13

Yes

No

Saccharomyces cerevisiae (Brewer's yeast) (1)

1 of 13

Yes

No

Schizosaccharomyces pombe (Fission yeast) (2)

1 of 12

Yes

No

Spom\SPBC19F8.04c

1 of 12

Yes

No

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:krimp. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (10)

4 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

TDRD1; tudor domain containing 1

3 of 14

TDRD6; tudor domain containing 6

3 of 14

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

anti tag coimmunoprecipitation, anti tag western blot

(Webster et al., 2015)

anti tag coimmunoprecipitation, anti tag western blot, anti bait coimmunoprecipitation, western blot, pull down, x-ray crystallography, isothermal titration calorimetry, predetermined participant

(Huang et al., 2021, Sato et al., 2015, Webster et al., 2015)

isothermal titration calorimetry, predetermined participant, anti tag coimmunoprecipitation, anti tag western blot, x-ray crystallography

(Huang et al., 2021)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Subunit Structure (UniProtKB)

Homooligomerizes (via N-terminus) (PubMed:26295961). Component of the ping-pong piRNA processing (4P) complex consisting of krimp, aub and AGO3; a single molecule of krimp can bind both aub and AGO3 without the need for homooligomerization (PubMed:26295961, PubMed:34210982). Interacts (via canonical tudor domain) with aub (via N-terminus when symmetrically dimethylated on arginine residues) (PubMed:26295961, PubMed:34210982). Interacts (via non-canonical tudor domain) with AGO3 (via N-terminus when unmethylated on arginine residues); this interaction leads to symmetrical dimethylation on AGO3 arginine residues and its subsequent dissociation from krimp (PubMed:26212455, PubMed:26295961, PubMed:34210982). Krimp associated AGO3 is mostly free of piRNA binding and the interaction plays an important role in the loading of AGO3 with piRNAs; piRNA binding stimulates methylation of ACO3 by the csul/PRMT5 methylosome complex and promotes dissociation of the two proteins (PubMed:26212455, PubMed:26295961, PubMed:34210982).

(UniProt, A1ZAC4 )

Linkouts

BioGRID - A database of protein and genetic interactions.

62523

DroID - A comprehensive database of gene and protein interactions.

FBgn0034098

MIST (protein-protein) - An integrated Molecular Interaction Database

36804

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

2R

Recombination map

2-79

Cytogenetic map

Sequence location

2R:16,238,103..16,240,722 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

53A1-53A1

Limits computationally determined from genome sequence between P{lacW}Lis-1^k11702&P{EP}CG8443^EP969 and P{lacW}l(2)k07824^k07824&P{lacW}veg^k03402

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-79

(FlyBase, 2016)

2-81.9

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (8)

Aberrations including deletions of this gene Aberrations including duplications of this gene

23847

w¹¹¹⁸; Mi{ET1}krimp^MB03478

18990

w¹¹¹⁸; PBac{WH}krimp^f06583/CyO

93389

w^*; TI{TI}krimp^GFP/CyO; TM2/MKRS

35230

y¹ sc^* v¹ sev²¹; P{TRiP.GL00114}attP2

35231

y¹ sc^* v¹ sev²¹; P{TRiP.GL00115}attP2

37511

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01653}attP40

2RG-0400

y² VhaAC39-1^cho-1 v¹; P{U6-krimp.NIG.sgRNA}attP40/CyO

v330574

P{VSH330574}attP40

Genomic Clones (13)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (25)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

FI20010

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0034098

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0034098

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Huang et al., 2014, Lim et al., 2009)

monoclonal

(Nagao et al., 2011)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

mtc is required for meiotic progression.

(Barbosa et al., 2007)

mtc mutants show a delay in the restriction of the synaptonemal complex and cause abnormal karyosome morphology in the later stages of oogenesis.

(Barbosa et al., 2007)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: mtc CG15707

(Barbosa, 2007.2.25)

Source for identity of: krimp CG15707

(Lim and Kai, 2007)

Nomenclature comments

Etymology

The gene is named "montecristo", after a brand of Cuban cigars, due to the mutant eggshell phenotype.

(Barbosa et al., 2007)

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

CG15707

(National Institute of Genetics Fly Stocks, 2022-, Meadows, 2018.10.31, Chen et al., 2012, Ni et al., 2011.7.19, Zhang et al., 2011, Zhang et al., 2010, Barbosa, 2007.2.25, Barbosa et al., 2007, Lim and Kai, 2007)

KRIMP

(Cacchione et al., 2020, Kumar and Chen, 2012, Kolaczkowski et al., 2011)

Krimp

(Vrettos et al., 2021, Soleimani et al., 2020, Hirakata and Siomi, 2019, Luo and Lu, 2017, Hirakata and Siomi, 2016, Ishizu et al., 2015, Sato et al., 2015, Wang et al., 2015, Webster et al., 2015, Huang et al., 2014, Meister, 2013, Olivieri et al., 2012)

Krimper

(Sato and Siomi, 2020)

mtc

(Barbosa, 2007.2.25, Barbosa et al., 2007)

Name Synonyms

CG15707

Krimper

(Patel et al., 2024, Huang et al., 2021, Sankaranarayanan and Weil, 2020, Yamashiro and Siomi, 2018, Rogers et al., 2017, Hirakata and Siomi, 2016, Ishizu et al., 2015, Molla-Herman et al., 2015, Sato et al., 2015, Kelleher et al., 2012, Kibanov et al., 2012, Handler et al., 2011, Pek and Kai, 2011, Patil and Kai, 2010, Siomi et al., 2010)

Montecristo

(Nurminsky, 2007)

krimper

(Specchia et al., 2017, Blumenstiel et al., 2016, Han et al., 2015, Heimiller et al., 2014, Handler et al., 2013, Mani and Juliano, 2013, Simkin et al., 2013, Vazquez-Pianzola and Suter, 2012, Castillo et al., 2011, Janic et al., 2010, Malone et al., 2009, Robine et al., 2009)

montecristo

(Barbosa, 2007.2.25, Barbosa et al., 2007, Barbosa et al., 2007)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 43 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

36804

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

A1ZAC4

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

A1ZAC4

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

A1ZAC4

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0034098

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

36804/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0034098

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0034098

FlyMine - An integrated database for Drosophila genomics

FBgn0034098

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG15707

MARRVEL_MODEL - MARRVEL (model organism gene)

36804

PDB - An information portal to biological macromolecular structures

Linkouts

BioGRID - A database of protein and genetic interactions.

62523

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0034098

DroID - A comprehensive database of gene and protein interactions.

FBgn0034098

DRSC - Results frm RNAi screens

FBgn0034098

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

krimp_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0034098

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0034098

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG15707

Flygut - An atlas of the Drosophila adult midgut

FBgn0034098

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

MIST (protein-protein) - An integrated Molecular Interaction Database

36804

References (106)