FlyBase Gene Report: Dmel\papi

General Information

Symbol

Dmel\papi

Species

D. melanogaster

Name

papi

Annotation Symbol

CG7082

Feature Type

protein_coding_gene

FlyBase ID

FBgn0031401

Gene Model Status

Current

Stock Availability

20 publicly available

Gene Summary

Involved in the piwi-interacting RNA (piRNA) metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins, and governs the methylation and subsequent repression of transposons which is essential for germline integrity (PubMed:21447556, PubMed:29531043). Likely to act by recruiting Piwi proteins such as AGO3 and piwi to the piRNA biogenesis machinery in the nuage (PubMed:21447556, PubMed:29531043). Required for the final steps of primary piRNA biogenesis by participating in the 3' end-trimming of piwi-bound intermediates into mature piRNAs (PubMed:29531043). (UniProt, Q9VQ91)

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
UniProtKB
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

22D4-22D4

Sequence location

2L:2,220,748..2,225,544 [+]

Recombination map

2-5

RefSeq locus

NT_033779 REGION:2220748..2225544

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (11 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables protein binding

inferred from physical interaction with FLYBASE:me31B; FB:FBgn0004419

(Liu et al., 2011)

inferred from physical interaction with FLYBASE:tral; FB:FBgn0041775

(Liu et al., 2011)

inferred from physical interaction with FLYBASE:TER94; FB:FBgn0286784

(Liu et al., 2011)

inferred from physical interaction with UniProtKB:Q9VKM1

(Zhang et al., 2018)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables nucleic acid binding

inferred from electronic annotation with InterPro:IPR004087

(InterPro Project Members, 2004-)

enables RNA binding

inferred from electronic annotation with InterPro:IPR004088, InterPro:IPR036612

(InterPro Project Members, 2004-)

Biological Process (5 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

involved_in piRNA processing

inferred from mutant phenotype

(Zhang et al., 2018)

involved_in primary piRNA processing

inferred from physical interaction with FLYBASE:piwi; FB:FBgn0004872

(Zhang et al., 2018)

involved_in transposable element silencing

inferred from mutant phenotype

(Liu et al., 2011)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in P granule organization

inferred from biological aspect of ancestor with PANTHER:PTN002741755

(GO Reference Genome Project, 2011-)

involved_in piRNA processing

inferred from biological aspect of ancestor with PANTHER:PTN002741755

(GO Reference Genome Project, 2011-)

involved_in spermatogenesis

inferred from biological aspect of ancestor with PANTHER:PTN002741755

(GO Reference Genome Project, 2011-)

Cellular Component (3 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

is_active_in mitochondrion

inferred from direct assay

(Hayashi et al., 2016)

located_in P granule

inferred from direct assay

(Liu et al., 2011)

part_of protein-containing complex

inferred from direct assay

(Zhang et al., 2018)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in P granule

inferred from biological aspect of ancestor with PANTHER:PTN002741755

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

Protein Family (UniProt)

Belongs to the Tdrkh family. (Q9VQ91)

Protein Signatures (InterPro)

Summaries

Protein Function (UniProtKB)

(UniProt, Q9VQ91)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\papi for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VQ91)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

PDB - An information portal to biological macromolecular structures

Comments on Gene Model

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.44

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

papi-RA

FBtr0077836

NM_164461

2325

576

papi-RB

FBtr0077838

NM_164462

2235

576

papi-RC

FBtr0077837

NM_134813

2331

576

papi-RD

FBtr0077839

NM_164463

2112

576

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

papi-PA

FBpp0077508

63.8

576

6.22

FBpp0077510

63.8

576

6.22

FBpp0077509

63.8

576

6.22

FBpp0077511

63.8

576

6.22

Q9VQ91

NP_722775

AAN10450

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

576 aa isoforms: papi-PA, papi-PB, papi-PC, papi-PD

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Subunit Structure (UniProtKB)

Interacts (via C-terminus) with AGO3 (via the N-terminal region when symmetrically methylated on arginine residues); this interaction is RNA-independent and may be required for AGO3 localization to the nuage (PubMed:21447556). Interacts (via Tudor domain) with piwi (via N-terminus) (PubMed:21447556, PubMed:29531043). Interacts with tral and me31B (PubMed:21447556).

(UniProt, Q9VQ91)

Domain

The Tudor domain is sufficient for binding to the N-terminus (1-14) of both unmethylated piwi or piwi symmetrically dimethylated at 'Arg-10' (PubMed:29531043). However, it may not be sufficient for binding to symmetrically dimethylated AGO3, instead this interaction may require a larger region of the C-terminus which includes the Tudor domain (257-576) (PubMed:21447556, PubMed:29531043).

(UniProt, Q9VQ91)

Crossreferences

InterPro - A database of protein families, domains and functional sites

PDB - An information portal to biological macromolecular structures

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VQ91

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\papi using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

4.14

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

embryonic stage 11 -- 12

anterior midgut primordium

(Fisher et al., 2012)

hindgut proper primordium

(Fisher et al., 2012)

posterior midgut primordium

(Fisher et al., 2012)

trunk mesoderm

(Fisher et al., 2012)

embryonic stage 13 -- 16

dorsal pharyngeal muscle cell

(Fisher et al., 2012)

embryonic hindgut

(Fisher et al., 2012)

embryonic/larval midgut

(Fisher et al., 2012)

RT-PCR

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

organism

(Liu et al., 2011)

third instar larval stage

(Liu et al., 2011)

(Liu et al., 2011)

Comment: carcass minus testis

(Liu et al., 2011)

testis

(Liu et al., 2011)

adult stage | female

organism

Comment: carcass minus ovary

(Liu et al., 2011)

ovary

(Liu et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 4

organism

(Liu et al., 2011)

oogenesis

female germline stem cell

(Liu et al., 2011)

(Liu et al., 2011)

(Liu et al., 2011)

(Liu et al., 2011)

(Liu et al., 2011)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

In adult fly ovaries papi is predominantly present in the the cytoplasm of both germarium cells and somatic follicle cells. It is present in germline stem cells and germline cyst cells, as well as in nurse cells and oocytes with a strong accumulation in region IIb germline cysts in the germarium. In post-germarial egg chambers, papi accumulates in perinuclear loci that appear to be the nuage. In early embryos, papi is the cytoplasm throughout the whole embryo, including the pole cells. No specific localization was observed in embryos. Colocalization of papi with AGO3 was seen, particularly in the cytoplasm of germline stem cells, differentiating cysts, and postgermarial egg chambers. It is particularly pronounced in the nuage of nurse cells. In early embryos, they colocalize in the cytoplasm.

(Liu et al., 2011)

Marker for

Subcellular Localization

CV Term

Evidence

References

is_active_in mitochondrion

inferred from direct assay

(Hayashi et al., 2016)

located_in P granule

inferred from direct assay

(Liu et al., 2011)

part_of protein-containing complex

inferred from direct assay

(Zhang et al., 2018)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\papi in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\papi

View exonic expression by tissue for Dmel\papi

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0031401

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33401/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0031401

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0031401

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0031401

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG7082

Flygut - An atlas of the Drosophila adult midgut

FBgn0031401

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\papi

Stages(s) 1-3
Stages(s) 4-6
Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 20 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 18 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of papi

Transgenic constructs containing regulatory region of papi

Aberrations (Deficiencies and Duplications) ( 2 )

Inferred from experimentation ( 2 )

Gene disrupted in

Df(2L)Exel6007

(Ryder, 2004.4.26)

Df(2L)Exel7009

(Ryder, 2004.4.26)

Inferred from location ( 14 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

papi^GD828

viable, with Scer\GAL4^Mef2.PR

papi^GD828

viable, with Scer\GAL4^pnr-MD237

papi^GD828

viable, with Scer\GAL4^tin.CΔ4

papi^GD828

Sterility

Allele

male sterile | heat sensitive, with Scer\GAL4^αTub84B.PL

papi^{RNAi.UAS.THFC}

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (15)

Hsap\TDRKH

12 of 14

Yes

Hsap\AKAP1

3 of 14

Hsap\RNF17

2 of 14

Hsap\TDRD10

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (12)

Rnor\Tdrkh

12 of 14

Yes

3 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (13)

Mmus\Tdrkh

11 of 14

Yes

3 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (10)

Xtro\tdrkh

10 of 13

Yes

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\tdrd15

1 of 13

Danio rerio (Zebrafish) (15)

Drer\tdrkh

13 of 14

Yes

3 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

Drer\si:ch211-189e2.3

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (5)

Cele\akap-1

1 of 14

Yes

Cele\ekl-1

1 of 14

Yes

Cele\eri-5

1 of 14

Yes

Cele\fubl-4

1 of 14

Yes

Cele\hrpk-2

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (9)

Agam\AgaP_AGAP010171

11 of 12

Yes

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (4)

Atha\AT1G33680

1 of 13

Yes

Atha\HEN4

1 of 13

Yes

Atha\Tudor1

1 of 13

Yes

Atha\Tudor2

1 of 13

Yes

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\snd1

1 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:papi. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (11)

qin

3 of 13

spoon

3 of 13

tapas

2 of 13

tud

2 of 13

CG15042

1 of 13

CG15930

1 of 13

Imp

1 of 13

Kots

1 of 13

krimp

1 of 13

tej

1 of 13

vret

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

azoospermia (postulated), TDRKH-related

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Allele

Disease

Evidence

References

papi^{RNAi.UAS.THFC}

model of azoospermia

CEA

(Yu et al., 2015)

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

TDRKH; tudor and KH domain containing

12 of 14

609501

AKAP1; A-kinase anchoring protein 1

3 of 14

602449

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

papi - AGO3

anti bait coimmunoprecipitation, western blot, two hybrid

(Liu et al., 2011)

papi - TER94

anti bait coimmunoprecipitation, western blot

(Liu et al., 2011)

papi - aub

anti bait coimmunoprecipitation, western blot, isothermal titration calorimetry, predetermined participant, two hybrid

(Zhang et al., 2018, Liu et al., 2011)

papi - me31B

anti bait coimmunoprecipitation, western blot

(Liu et al., 2011)

papi - piwi

two hybrid, anti tag coimmunoprecipitation, anti tag western blot, x-ray crystallography, isothermal titration calorimetry, predetermined participant, pull down, western blot, Identification by mass spectrometry, anti bait coimmunoprecipitation, molecular weight estimation by staining

(Zhang et al., 2018, Liu et al., 2011)

papi - tral

anti bait coimmunoprecipitation, western blot

(Liu et al., 2011)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Subunit Structure (UniProtKB)

(UniProt, Q9VQ91 )

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0031401

MIST (protein-protein) - An integrated Molecular Interaction Database

33401

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-5

Cytogenetic map

22D4-22D4

Sequence location

2L:2,220,748..2,225,544 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

22D4-22D4

Limits computationally determined from genome sequence between P{lacW}s4989 and P{lacW}Rab5^k08232

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-5

(FlyBase, 2016)

2-4.5

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (20)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

85422

w¹¹¹⁸; P{XP}papi^d02929

38216

y¹ v¹; P{TRiP.GL00657}attP40

65642

w¹¹¹⁸; PBac{IT.GAL4}papi^1257-G4/CyO

14093

y¹ w^67c23; P{SUPor-P}papi^KG04134

Kyoto

123088

w¹¹¹⁸; P{RS3}papi^CB-0243-3

123165

w¹¹¹⁸; P{RS3}papi^CB-0425-3

123212

w¹¹¹⁸; P{RS3}papi^CB-0509-3

NIG-Fly

7082R-1

P{NIG.7082R}1

M2L-0439

y¹ w¹¹¹⁸; papi^SK5 P{neoFRT}40A/CyO-Tb

VDRC

v103708

P{KK100642}VIE-260B

v2554

w¹¹¹⁸ P{GD828}v2554

v318857

PBac{fTRG01352.sfGFP-TVPTBF}VK00033

More stocks available...

Genomic Clones (15)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (40)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

GH18329

Other clones

DPiM_GH18329

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0031401

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0031401

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Zhang et al., 2018, Liu et al., 2011)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

papi interacts most strongly with piwi, strongly with AGO3 and weakly with aub, but fails to interact with AGO1 and AGO2.

(Liu et al., 2011)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: papi CG7082

(Handler et al., 2011)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Name Synonyms

Papi

(Hirakata and Siomi, 2016)

Partner of PIWIs

(Liu et al., 2011)

papi

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 68 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

33401

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VQ91

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9VQ91

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VQ91

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0031401

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33401/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0031401

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0031401

FlyMine - An integrated database for Drosophila genomics

FBgn0031401

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG7082

MARRVEL_MODEL - MARRVEL (model organism gene)

33401

PDB - An information portal to biological macromolecular structures

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0031401

DroID - A comprehensive database of gene and protein interactions.

FBgn0031401

DRSC - Results frm RNAi screens

FBgn0031401

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0031401

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0031401

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG7082

Flygut - An atlas of the Drosophila adult midgut

FBgn0031401

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0031401

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

MIST (protein-protein) - An integrated Molecular Interaction Database

33401

References (62)

The following external sites may use different assemblies or annotations than FlyBase.

4.14

Report Sections