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FB2026_01
,
released March 12, 2026
alpha-Man-I, mas-1, α-Man-I, Man'ase, alpha-mannosidase
Please see the JBrowse view of Dmel\α-Man-Ia for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.55
Gene model reviewed during 5.45
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
6.8, 3.8, 3.3 (northern blot)
The group(s) of polypeptides indicated below share identical sequence to each other.
667, 643 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\α-Man-Ia using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
Comment: 0-3 hr AEL
JBrowse - Visual display of RNA-Seq signals
View Dmel\α-Man-Ia in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
New annotation (CG32682) in release 3 of the genome annotation.
Null mutations only show subtle developmental defects, suggesting that the mannose trimming pathway of N-linked glycoprotein processing is genetically and biochemically redundant.
Structural gene encoding α-mannosidase I; The absence of an obvious mutant phenotype suggests that the mannose trimming pathway of N-linked glycoprotein processing is genetically and biochemically redundant.
Presumptive null or hypomorphic mutations may show only subtle defects of the ommatidia and wing veins (FBrf0080155).
Source for merge of: α-Man-I CG32682
Source for merge of: α-Man-I CG18799
Annotations CG32682 and CG32684 merged as CG42275 in release 5.8 of the genome annotation.
Annotations CG17809 and CG18799 merged as CG32684 in release 3 of the genome annotation.
Source for identity of: α-Man-Ia α-Man-I
