FlyBase Gene Report: Dmel\Mlp60A

General Information

Symbol

Dmel\Mlp60A

Species

D. melanogaster

Name

Muscle LIM protein at 60A

Annotation Symbol

CG42309

Feature Type

protein_coding_gene

FlyBase ID

FBgn0259209

Gene Model Status

Current

Stock Availability

9 publicly available

Gene Summary

Muscle LIM protein at 60A (Mlp60A) encodes a Zinc-ion binding protein, expressed strongly in the Z-band region of the sarcomere. It is involved in development and maintenance of the embryonic and flight muscles. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
UniProtKB
Interactive Fly

Also Known As

DmLIM-2, DMlp1

Key Links

Genomic Location

Cytogenetic map

60B8-60B8

Sequence location

2R:24,074,602..24,078,223 [+]

Recombination map

2-106

RefSeq locus

NT_033778 REGION:24074602..24078223

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (4 terms)

Molecular Function (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in muscle tissue development

inferred from expression pattern

(Stronach et al., 1996)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (3 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

colocalizes_with actin cytoskeleton

inferred from direct assay

(Stronach et al., 1996)

located_in nucleus

inferred from direct assay

(Arber and Caroni, 1996)

located_in Z disc

inferred from high throughput direct assay

(Sarov et al., 2016)

inferred from direct assay

(Firdaus et al., 2015)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Zinc finger, LIM-type

Summaries

Gene Snapshot

Protein Function (UniProtKB)

Positive regulator of myogenesis.

(UniProt, P53777)

Summary (Interactive Fly)

cytoskeletal LIM-domain protein, zinc-ion binding Cys-rich protein a protein - expressed strongly in the Z-band region of the sarcomere - involved in development and maintenance of the embryonic and flight muscles - promotes myogenic differentiation

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Mlp60A for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry P53777)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.52

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.55

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Mlp60A-RB

FBtr0299697

NM_001144278

2058

486

Mlp60A-RC

FBtr0343338

NM_001299892

2468

486

FBtr0299696

440

FBtr0344996

670

Additional Transcript Data and Comments

Reported size (kB)

0.5 (northern blot)

(Stronach et al., 1996)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Mlp60A-PB

FBpp0288975

53.0

486

8.18

FBpp0309996

53.0

486

8.18

FBpp0288974

10.0

8.33

FBpp0311250

10.0

8.33

P53777

NP_001286820

AHN56615

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

92 aa isoforms: Mlp60A-PE, Mlp60A-PF

486 aa isoforms: Mlp60A-PB, Mlp60A-PC

Additional Polypeptide Data and Comments

Reported size (kDa)

9 (kD)

(Stronach et al., 1996)

92 (aa)

(Arber et al., 1994)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Zinc finger, LIM-type

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Mlp60A using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.63

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 16

dorsal pharyngeal muscle cell

(Fisher et al., 2012)

larval muscle system

(Fisher et al., 2012)

larval somatic muscle cell

(Fisher et al., 2012)

larval visceral muscle cell

(Fisher et al., 2012)

embryonic stage 13 -- 17

somatic trunk mesoderm

(Arber et al., 1994)

visceral trunk mesoderm

(Arber et al., 1994)

embryonic stage 16

larval somatic muscle cell

(Stronach et al., 1996)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

pharyngeal muscle cell

(Stronach et al., 1996)

embryonic stage -- adult stage

(Stronach et al., 1996)

embryonic stage 14 -- 17

visceral trunk mesoderm

(Stronach et al., 1996)

somatic trunk mesoderm

(Stronach et al., 1996)

Additional Descriptive Data

Mlp60A transcripts are first detected by northern blot analysis in 8-12hr embryos, peak in 16-24hr embryos, are present in low levels in larvae, show a second peak of expression in pupae, and persist in adults. They are detected by in situ hybridization starting in embryonic stage 14 in the growing syncytial myotubes. They are present in the completed pattern of somatic muscles in stage 16 embryos where they are distributed throughout the mature myotubes. Transcripts are also expressed in the visceral mesoderm and the pharyngeal muscle.

(Stronach et al., 1996)

Mlp60A transcripts are detected from stage 13 in the developing muscles of the somatic and visceral mesoderm, subsequent to the formation of muscle precursor cells.

(Arber et al., 1994)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

larval visceral muscle cell

(Stronach et al., 1996)

larval somatic muscle cell

(Stronach et al., 1996)

pharyngeal muscle cell

(Stronach et al., 1996)

embryonic stage 16

larval visceral muscle cell

(Stronach et al., 1999)

larval somatic muscle cell

(Stronach et al., 1999)

pharyngeal muscle cell

(Stronach et al., 1999)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Mlp60A protein is detected beginning in stage 14 embryos in somatic, visceral and pharyngeal muscles. Protein is found throughout the myotube. Mlp60A protein appears to associate with linear cytoplasmic elements in the muscle cell syncytium that are thought to be the sarcomeric actin filament network.

(Stronach et al., 1996)

Marker for

Subcellular Localization

CV Term

Evidence

References

colocalizes_with actin cytoskeleton

inferred from direct assay

(Stronach et al., 1996)

located_in nucleus

inferred from direct assay

(Arber and Caroni, 1996)

located_in Z disc

inferred from high throughput direct assay

(Sarov et al., 2016)

inferred from direct assay

(Firdaus et al., 2015)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Mlp60A in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Mlp60A

View exonic expression by tissue for Dmel\Mlp60A

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0259209

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

37853/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0259209

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0259209

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0259209

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG33149

Flygut - An atlas of the Drosophila adult midgut

FBgn0259209

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 6 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 11 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Mlp60A

Transgenic constructs containing regulatory region of Mlp60A

Aberrations (Deficiencies and Duplications) ( 2 )

Inferred from experimentation ( 2 )

Gene disrupted in

Df(2R)Exel6081

(Ryder, 2004.4.26)

Gene partially disrupted in

Df(2R)Mlp60A^UR-2.9.17

(Wishard et al., 2023)

Inferred from location ( 1 )

Df(2R)BSC356

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

viable, with Scer\GAL4^Mef2.PR

viable, with Scer\GAL4^pnr-MD237

viable, with Scer\GAL4^tin.CΔ4

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (25)

Hsap\CSRP3

7 of 14

Yes

Hsap\CSRP2

6 of 14

Hsap\CRIP2

5 of 14

Yes

Hsap\CSRP1

5 of 14

Hsap\CRIP1

4 of 14

Yes

Hsap\CRIP3

4 of 14

Yes

Hsap\LIMA1

2 of 14

Yes

Hsap\LIMD2

2 of 14

Yes

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (10)

Rnor\Csrp3

8 of 14

Yes

Rnor\Csrp1

6 of 14

Rnor\Csrp2

6 of 14

Rnor\Crip1

5 of 14

Yes

Rnor\Crip2

5 of 14

Yes

Rnor\Crip3

4 of 14

Yes

Rnor\RGD1563606

3 of 14

Yes

Rnor\Limd2

1 of 14

Rnor\Mical1

1 of 14

Rnor\Tgfb1i1

1 of 14

Mus musculus (laboratory mouse) (12)

Mmus\Csrp3

8 of 14

Yes

Mmus\Csrp2

6 of 14

Mmus\Crip1

5 of 14

Yes

Mmus\Crip2

5 of 14

Yes

Mmus\Csrp1

5 of 14

Mmus\Crip3

4 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (22)

Xtro\csrp3

6 of 13

Yes

Xtro\csrp1

4 of 13

Xtro\csrp2

4 of 13

Xtro\crip2

3 of 13

Yes

Xtro\crip1

2 of 13

Yes

Xtro\crip3

2 of 13

Yes

Xtro\foxe3

2 of 13

Xtro\LOC101734738

2 of 13

Yes

Xtro\c4h3orf84

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\snx33

1 of 13

Danio rerio (Zebrafish) (13)

Drer\csrp1a

7 of 14

Yes

Drer\csrp1b

7 of 14

Yes

Drer\csrp3

7 of 14

Yes

Drer\csrp2

6 of 14

Drer\crip1

5 of 14

Yes

Drer\crip2

5 of 14

Yes

Drer\crip2l

5 of 14

Yes

Drer\zgc:195282

5 of 14

Yes

Drer\crip3

4 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (12)

Cele\mlp-1

9 of 14

Yes

4 of 14

4 of 14

2 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (14)

Agam\AgaP_AGAP012305

6 of 12

Yes

3 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (6)

Atha\PLIM2a

5 of 13

Yes

Atha\PLIM2b

5 of 13

Yes

Atha\PLIM2c

5 of 13

Yes

Atha\WLIM1

5 of 13

Yes

Atha\WLIM2a

5 of 13

Yes

Atha\WLIM2b

4 of 13

Yes

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\rga4

1 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Mlp60A. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (17)

Mlp84B

8 of 13

Mical

3 of 13

Rassf

3 of 13

Awh

1 of 13

CG31624

1 of 13

CG33521

1 of 13

esn

1 of 13

Hil

1 of 13

jub

1 of 13

Lasp

1 of 13

Lim3

1 of 13

MICAL-like

1 of 13

Pax

1 of 13

Unc-115a

1 of 13

Unc-115b

1 of 13

Zasp52

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 2 )

Human Ortholog

Disease

Evidence

References

CSRP3; cysteine and glycine rich protein 3

model of dilated cardiomyopathy 1M

IEA

(FlyBase, 2019-)

model of hypertrophic cardiomyopathy 12

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

CSRP3; cysteine and glycine rich protein 3

7 of 14

600824

CSRP2; cysteine and glycine rich protein 2

6 of 14

601871

CRIP2; cysteine rich protein 2

5 of 14

601183

CSRP1; cysteine and glycine rich protein 1

5 of 14

123876

CRIP1; cysteine rich protein 1

4 of 14

123875

CRIP3; cysteine rich protein 3

4 of 14

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Mlp60A - CG10209

two hybrid

(Hu et al., 2017.6.13)

Mlp60A - hale

two hybrid

(Hu et al., 2017.6.13)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0259209

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-106

Cytogenetic map

60B8-60B8

Sequence location

2R:24,074,602..24,078,223 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

60B8-60B8

Limits computationally determined from genome sequence between P{lacW}Phm^k07623&P{lacW}tsr^k05633 and P{EP}EP503

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

60A-60A

(Beckerle, 1995.9.9)

60A-60B

(Arber, 1994.8.22, Stronach et al., 1994)

60A5-60B11

(determined by in situ hybridisation)

(Stronach et al., 1996)

Experimentally Determined Recombination Data

Location

2-106

(FlyBase, 2016)

2-109.9

(Comeron et al., 2012)

(Beckerle, 1995.9.9, Arber, 1994.8.22)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (9)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

29381

y¹ v¹; P{TRiP.JF03313}attP2

27185

y¹ w^*; P{EP}Mlp60A^G5733

27970

y¹ w^*; P{EP}Mlp60A^G7762

42108

y¹ w^*; Mi{MIC}Mlp60A^MI05746

NIG-Fly

30174R-1

P{NIG.30174R}1

30179R-1

P{NIG.30179R}1

2RG-0703

y² VhaAC39-1^cho-1 v¹; P{U6-Mlp60A.NIG.sgRNA}attP40/CyO

VDRC

v101898

P{KK110175}VIE-260B

v102757

P{KK112356}VIE-260B

Genomic Clones (15)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (62)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0259209

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0259209

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Wishard et al., 2023, Firdaus et al., 2015, Stronach et al., 1996)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Mlp60A protein is identified and developmental expression pattern determined. Results reveal a striking conservation of sequence, timing of gene expression, tissue distribution of gene products and subcellular localisation among LIM proteins of vertebrates and invertebrates.

(Stronach et al., 1996)

Protein has a single LIM domain and is expressed in the muscle.

(Stronach, 1996.2.12)

During embryogenesis Mlp60A expression is associated with developing muscles of the visceral and somatic mesoderm subsequent to the formation of muscle precursor cells.

(Arber et al., 1994)

Relationship to Other Genes

Source for database merge of

Source for merge of: Mlp60A CG30174 CG30179

(FlyBase Genome Annotators, 2008)

Source for merge of: Mlp60A BcDNA:RH74176

(FlyBase, 1996-)

Source for merge of: Mlp60A BcDNA:RE14544

(FlyBase, 1996-)

Additional comments

Annotations CG33149, CG30174 and CG30179 merged as CG42309 in release 5.9 of the genome annotation.

(FlyBase Genome Annotators, 2008)

Source for merge of Mlp60A BcDNA:RH74176 was a shared cDNA ( date:030728 ).

(FlyBase Genome Annotators, 2002-2003, FlyBase, 1996-)

Source for merge of Mlp60A BcDNA:RE14544 was a shared cDNA ( date:030728 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: Mlp60A CG3220

(Wang, 1999.11)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (23)

Reported As

Symbol Synonym

BcDNA:RE14544

BcDNA:RH74176

CG30174

(Japanese National Institute of Genetics, 2012.5.21, Zhang et al., 2010, Keleman et al., 2009.8.5)

CG30179

(Japanese National Institute of Genetics, 2012.5.21, Zhang et al., 2010, Keleman et al., 2009.8.5)

CG3220

(Whitfield, 2001.2.19, Whitfield, 2000.12.19)

CG33149

(Cammarato et al., 2011, Keleman et al., 2009.8.5, Perkins et al., 2009)

CG42309

(National Institute of Genetics Fly Stocks, 2022-, FlyBase Genome Annotators, 2008)

DLim-2

DMLP1

(Lin et al., 1997, Arber and Caroni, 1996)

DMlp1

(Weiskirchen and Gunther, 2003, Arber et al., 1994)

DmLIM-2

(Stronach et al., 1996, Stronach et al., 1995, Stronach et al., 1994)

FBgn0259209

(Tikhonov et al., 2013)

MLIM 60A

(Pankotai et al., 2013)

MLP

MLP1

(Arber, 1994.8.22)

MLP60A

(Bordet et al., 2021)

Mlp1

Mlp60

(Schönbauer et al., 2011)

Mlp60A

(Xu et al., 2025, Trujillo et al., 2024, Wishard et al., 2023, She et al., 2021, Moskalev et al., 2019, Hu et al., 2017.6.13, Firdaus et al., 2015, Ma et al., 2015, Toret et al., 2014, Crona et al., 2013, Bulchand et al., 2010, Xun et al., 2008, Clark et al., 2007, Junion et al., 2007, Montana and Littleton, 2006, Sandmann et al., 2006)

dMlp60A

(Weiskirchen and Gunther, 2003)

Name Synonyms

CG30174

CG30179

CG42309

(FlyBase Genome Annotators, 2008)

Muscle LIM protein 60A

(Bulchand et al., 2010)

Muscle LIM protein at 60A

(Crona et al., 2013, Cammarato et al., 2011, Xun et al., 2008, Sandmann et al., 2006)

Muscle-specific LIM protein at 60A

(Stronach et al., 1996)

Secondary FlyBase IDs

FBgn0011643
FBgn0013299
FBgn0014862
FBgn0047165
FBgn0053149
FBgn0062900
FBgn0050174
FBgn0050179

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 47 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

37853

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

P53777

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

P53777

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

P53777

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0259209

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

37853/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0259209

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0259209

InterPro - A database of protein families, domains and functional sites

Zinc finger, LIM-type

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG42309

MARRVEL_MODEL - MARRVEL (model organism gene)

37853

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0259209

DroID - A comprehensive database of gene and protein interactions.

FBgn0259209

DRSC - Results frm RNAi screens

FBgn0259209

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0259209

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0259209

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG33149

Flygut - An atlas of the Drosophila adult midgut

FBgn0259209

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

References (76)

The following external sites may use different assemblies or annotations than FlyBase.

-0.63

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