FlyBase Allele Report: Dmel\l(1)sc[UAS.cHa]

General Information

Symbol

Dmel\l(1)sc^UAS.cHa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Hinz

FlyBase ID

FBal0045936

Feature type

allele

Associated gene

Dmel\l(1)sc

Associated Insertion(s)

Carried in Construct

P{UAS-l(1)sc.LSC}

Also Known As

UAS-l'sc, UAS-l''sc

Key Links

Transgenic product class

cDNA

(Hinz et al., 1994)

wild_type

(Hinz et al., 1994)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Hinz et al., 1994)

wild_type

(Hinz et al., 1994)

Mutagen

in vitro construct

(Klein and Campos-Ortega, 1997, Hinz et al., 1994, Hinz et al., 1993)

Progenitor genotype

Carried in construct

P{UAS-l(1)sc.LSC}

Cytology

Description

Expression of l(1)sc cDNA is governed by UAS regulatory sequences.

(Hinz et al., 1994)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

l(1)sc

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval maxillary chordotonal organ with two scolopidia, with Scer\GAL4^da.G32

(Giebel et al., 1997)

embryonic/larval optic lobe | larval stage | somatic clone, with Scer\GAL4^Tub.PU

(Nguyen and Cheng, 2024)

lamina | larval stage, with Scer\GAL4^pxb-rN346

(Akiba et al., 2024)

larval neuroblast | ectopic, with Scer\GAL4^pxb-rN346

(Akiba et al., 2024)

macrochaeta & abdominal sternite 1, with Scer\GAL4^sca-537.4

(Hinz et al., 1994)

macrochaeta & abdominal sternite 2, with Scer\GAL4^sca-537.4

(Hinz et al., 1994)

macrochaeta & abdominal sternite 3, with Scer\GAL4^sca-537.4

(Hinz et al., 1994)

macrochaeta & abdominal sternite 4, with Scer\GAL4^sca-537.4

(Hinz et al., 1994)

macrochaeta & abdominal sternite 5, with Scer\GAL4^sca-537.4

(Hinz et al., 1994)

macrochaeta & abdominal sternite 6, with Scer\GAL4^sca-537.4

(Hinz et al., 1994)

macrochaeta & mesothoracic laterotergite, with Scer\GAL4^hry-540.3

(Hinz et al., 1994)

macrochaeta & metathoracic laterotergite, with Scer\GAL4^hry-540.3

(Hinz et al., 1994)

macrochaeta & pronotum, with Scer\GAL4^hry-540.3

(Hinz et al., 1994)

macrochaeta & scutellum, with Scer\GAL4^455.2

(Hinz et al., 1994)

macrochaeta & scutum, with Scer\GAL4^hry-540.3

(Hinz et al., 1994)

macrochaeta & wing, with Scer\GAL4^564.2

(Hinz et al., 1994)

macrochaeta | ectopic, with Scer\GAL4^sca-537.4

(Nagel et al., 2000)

medulla forming neuroblast | P-stage | decreased number | somatic clone, with Scer\GAL4^Tub.PU

(Nguyen and Cheng, 2024)

microchaeta, with Scer\GAL4^527.3

(Hinz et al., 1994)

microchaeta & mesothoracic laterotergite, with Scer\GAL4^hry-540.3

(Hinz et al., 1994)

microchaeta & metathoracic laterotergite, with Scer\GAL4^hry-540.3

(Hinz et al., 1994)

microchaeta & pronotum, with Scer\GAL4^hry-540.3

(Hinz et al., 1994)

microchaeta & scutum, with Scer\GAL4^hry-540.3

(Hinz et al., 1994)

microchaeta | ectopic, with Scer\GAL4^ptc-559.1

(Apidianakis et al., 1999)

monoscolopidial chordotonal organ, with Scer\GAL4^da.G32

(Giebel et al., 1997)

scutellar bristle, with Scer\GAL4^455.2

(Rottgen et al., 1998)

scutellar bristle | ectopic, with Scer\GAL4^455.2

(Rottgen et al., 1998, Giebel and Campos-Ortega, 1997)

scutellar bristle | ectopic, with Scer\GAL4^ptc-559.1

(Apidianakis et al., 1999)

scutellum & microchaeta, with Scer\GAL4^ptc-559.1

(Apidianakis et al., 1999)

sensory mother cell & dorsal mesothoracic disc, with Scer\GAL4^ap-md544

(Apidianakis et al., 1999)

stage 1 neuroblast, with Scer\GAL4^da.G32

(Stollewerk, 2000)

ventral neurectoderm intermediate zone, with Scer\GAL4^da.G32

(Stollewerk, 2000)

ventral neurectoderm lateral zone, with Scer\GAL4^da.G32

(Stollewerk, 2000)

ventral neurectoderm medial zone, with Scer\GAL4^da.G32

(Stollewerk, 2000)

wing vein, with Scer\GAL4^527.3

(Hinz et al., 1994)

Detailed Description

Statement

Reference

At stage 11 expression of l(1)sc^UAS.cHa under the control of Scer\GAL4^da.G32 does not lead to any changes in neuroblast numbers when compared to control embryos.

(Arefin et al., 2019)

When l(1)sc^Scer\UAS.cHa is driven by Scer\GAL4^sca-537.4 complete ectopic mechano-sensory bristles are seen.

(Nagel et al., 2000)

Before delamination of the SI neuroblasts, the ventral neuroectoderm (VNE) of embryos expressing l(1)sc^Scer\UAS.cHa under the control of Scer\GAL4^da.G32 can be subdivided into three longitudinal regions based on average cell size, as in wild-type embryos. More enlarged cells are detected in all regions of the VNE compared to wild type; 81% in the medial, 65% in the intermediate and 71% in the lateral region (wild-type numbers are 63%, 20% and 64% respectively). The morphologies and cell sizes of the neuroblasts are altered compared to wild type; whereas in wild-type embryos the delaminating neuroblasts have small apical surfaces and are basally bloated, almost all SI neuroblasts in the VNE of embryos expressing l(1)sc^Scer\UAS.cHa under the control of Scer\GAL4^da.G32 are basally and apically bloated. As in wild-type embryos, the neuroectodermal cells that have become enlarged decrease in size during delamination of the SI neuroblasts.

(Stollewerk, 2000)

Flies with l(1)sc^Scer\UAS.cHa under the control of Scer\GAL4^ptc-559.1 form multiple ectopic macrochaetae and microchaetae on the scutellum. l(1)sc^Scer\UAS.cHa, when driven by Scer\GAL4^ap-md544, creates a pattern of discrete sensory organ precursors randomly dispersed throughout the dorsal half of the wing pouch in the wing disc.

(Apidianakis et al., 1999)

In strain ZB1.4 the activator insertion Scer\GAL4^455.2 is combined with l(1)sc^Scer\UAS.cHa causing the development of 10 ectopic scutellar macrochaetes.

(Giebel and Campos-Ortega, 1997)

Neural hypoplasia of the CNS and PNS in Df(1)260-1 hemizygous embryos is strongly reduced by Scer\GAL4^da.G32-mediated expression of l(1)sc^Scer\UAS.cHa. Scer\GAL4^da.G32-mediated expression is not sufficient to promote the development of ectopic nerve cells in wild type embryos, but does cause defects in internal sensory organs.

(Giebel et al., 1997)

Ectopic external sense organs develop, macrochaetae, microchaetae and campaniform sensilla, on virtually every part of the body. Extra veins with microchaetae also develop on the wing blade.

(Hinz et al., 1994)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by Delta⁰³⁹³⁵

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by Delta⁰⁶⁶⁰⁶

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by E(spl)m8-HLH^R-B251

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by hry⁴¹

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by hry⁰⁰⁶⁸²

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by hry⁰⁸²⁴⁷

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by mam^E343-5

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by mam^k11208

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by mam²¹

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by ptc^E227-2

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by ptc^E291-6

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by ptc^E470-3

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by ptc^X234-1

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by ptc^X253-4

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by ptc^X291-5

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by eIF4A^k09406

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by Hrb27C⁰²⁶⁴⁷

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by Hr3^k09242

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by jumu^06142a

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by Acsl^k06526

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by Acsl^k10306

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by Acsl⁰⁷⁴⁴⁷

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by Acsl^k10313

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by Acsl^E481-3

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by Acsl^E305-3

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by emc^E12

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, enhanceable by emc⁰⁴³²²

(Rottgen et al., 1998)

Suppressed by

Statement

Reference

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, suppressible by H^E276-2

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, suppressible by H^E311-4

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, suppressible by H^X200-1

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, suppressible by H^X234-4

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, suppressible by H^X257-3

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, suppressible by da^IIP106

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, suppressible by da^E253-2

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, suppressible by da^E321-6

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, suppressible by da^X293-4

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, suppressible by H²

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has visible phenotype, suppressible by H^E222-2

(Rottgen et al., 1998)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by Delta⁰³⁹³⁵

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by Delta⁰⁶⁶⁰⁶

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by E(spl)m8-HLH^R-B251

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by hry⁴¹

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by hry⁰⁰⁶⁸²

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by hry⁰⁸²⁴⁷

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by mam^E343-5

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by mam^k11208

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by mam²¹

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by ptc^E227-2

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by ptc^E291-6

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by ptc^E470-3

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by ptc^X234-1

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by ptc^X253-4

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by ptc^X291-5

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by eIF4A^k09406

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by Hrb27C⁰²⁶⁴⁷

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by Hr3^k09242

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by jumu^06142a

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by Acsl^k06526

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by Acsl^k10306

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by Acsl⁰⁷⁴⁴⁷

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by Acsl^k10313

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by Acsl^E481-3

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by Acsl^E305-3

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by emc^E12

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, enhanceable by emc⁰⁴³²²

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle | ectopic phenotype, enhanceable by E(spl)m8-HLH^+,stop.UAS, Scer\GAL4^455.2

(Giebel and Campos-Ortega, 1997)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle | ectopic phenotype, enhanceable by E(spl)m8-HLH^1,stop.UAS, Scer\GAL4^455.2

(Giebel and Campos-Ortega, 1997)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle | ectopic phenotype, enhanceable by E(spl)m8-HLH^1.UAS, Scer\GAL4^455.2

(Giebel and Campos-Ortega, 1997)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle | ectopic phenotype, enhanceable by E(spl)m8-HLH^bHLH.UAS, Scer\GAL4^455.2

(Giebel and Campos-Ortega, 1997)

NOT Enhanced by

Statement

Reference

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle | ectopic phenotype, non-enhanceable by E(spl)m8-HLH^ΔbHIII.UAS, Scer\GAL4^455.2

(Giebel and Campos-Ortega, 1997)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle | ectopic phenotype, non-enhanceable by E(spl)m8-HLH^P-L.UAS, Scer\GAL4^455.2

(Giebel and Campos-Ortega, 1997)

Suppressed by

Statement

Reference

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, suppressible by da^IIP106

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, suppressible by da^E253-2

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, suppressible by da^E321-6

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, suppressible by da^X293-4

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, suppressible by H²

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, suppressible by H^E222-2

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, suppressible by H^E276-2

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, suppressible by H^E311-4

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, suppressible by H^X200-1

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, suppressible by H^X234-4

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle phenotype, suppressible by H^X257-3

(Rottgen et al., 1998)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle | ectopic phenotype, suppressible by E(spl)m8-HLH^ΔbHIV.UAS, Scer\GAL4^455.2

(Giebel and Campos-Ortega, 1997)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle | ectopic phenotype, suppressible by E(spl)m8-HLH^ΔbHLH.UAS, Scer\GAL4^455.2

(Giebel and Campos-Ortega, 1997)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle | ectopic phenotype, suppressible by E(spl)m8-HLH^UAS.cGa, Scer\GAL4^455.2

(Giebel and Campos-Ortega, 1997)

NOT suppressed by

Statement

Reference

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle | ectopic phenotype, non-suppressible by E(spl)m8-HLH^ΔbHIII.UAS, Scer\GAL4^455.2

(Giebel and Campos-Ortega, 1997)

Scer\GAL4^455.2, l(1)sc^UAS.cHa has scutellar bristle | ectopic phenotype, non-suppressible by E(spl)m8-HLH^P-L.UAS, Scer\GAL4^455.2

(Giebel and Campos-Ortega, 1997)

NOT Suppressor of

Statement

Reference

l(1)sc^UAS.cHa/da^UAS.cGa, Scer\GAL4^da.G32 is a non-suppressor of muscle founder cell phenotype of N^int.SH.UAS, Scer\GAL4^da.G32

(Giebel, 1999)

l(1)sc^UAS.cHa/da^UAS.cGa, Scer\GAL4^da.G32 is a non-suppressor of presumptive embryonic/larval nervous system phenotype of N^ΔE.UAS, Scer\GAL4^da.G32

(Giebel et al., 1997)

Other

Statement

Reference

Scer\GAL4^da.G32, da^UAS.cGa, l(1)sc^UAS.cHa has larval somatic muscle cell phenotype

(Giebel, 1999)

Scer\GAL4^da.G32, da^UAS.cGa, l(1)sc^UAS.cHa has peripheral nervous system phenotype

(Giebel, 1999)

Scer\GAL4^da.G32, da^UAS.cGa, l(1)sc^UAS.cHa has Malpighian tubule tip cell phenotype

(Hoch and Jackle, 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of l(1)sc^Scer\UAS.cHa and da^Scer\UAS.cGa driven by Scer\GAL4^da.G32 results in minor muscle and PNS pattern formation defects and in very rare cases, muscle duplication. The addition of l(1)sc^Scer\UAS.cHa and da^Scer\UAS.cGa does not rescue the mesoderm phenotype of N^{int.SH.Scer\UAS} driven by Scer\GAL4^da.G32.

(Giebel, 1999)

Some embryos coexpressing l(1)sc^Scer\UAS.cHa and da^Scer\UAS.cGa under the control of Scer\GAL4^da.G32 develop multiple Malpighian tubule tip cells.

(Hoch and Jackle, 1998)

Scer\GAL4^455.2-mediated expression leads to an increase in the number of scutellar bristles, on average 6 to 7 ectopic bristles can be counted. Phenotype can be suppressed by mutations of da and H and enhanced by mutations of emc, Dl, E(spl), h, mam, eIF-4a, ptc, Hrb27C, l(2)44DEa, Hr46, jumu and N.

(Rottgen et al., 1998)

Scer\GAL4^da.G32-mediated expression of Dl::N^{ΔECN.Scer\UAS} generates aneural embryos. Simultaneous expression of da^Scer\UAS.cGa and l(1)sc^Scer\UAS.cHa does not rescue the phenotype.

(Giebel et al., 1997)

One copy of da^IIP106 or a deficiency of da can suppress the wing phenotype, the presence of a third copy of da enhances the phenotype.

(Hinz et al., 1994)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

51670

w^*; P{UAS-l(1)sc.LSC}2; P{UAS-l(1)sc.LSC}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

l(1)sc^Scer\UAS.cHa

l(1)sc^UAS.cHa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Hinz

(Hinz et al., 1993)

Secondary FlyBase IDs

References (17)

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